clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

Cross Reference

Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Splenic Diseases D013158 5 associated lipids
Sexually Transmitted Diseases, Bacterial D015231 5 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Dyspepsia D004415 5 associated lipids
Erythema Nodosum D004893 5 associated lipids
Pyelonephritis D011704 5 associated lipids
Hand Dermatoses D006229 5 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Skin Ulcer D012883 6 associated lipids
Meningitis, Bacterial D016920 6 associated lipids
Nocardia Infections D009617 6 associated lipids
Bronchitis D001991 6 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Syphilis D013587 6 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Bronchiolitis D001988 6 associated lipids
Whooping Cough D014917 6 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Periodontal Attachment Loss D017622 7 associated lipids
Bronchiectasis D001987 7 associated lipids
Tooth Discoloration D014075 7 associated lipids
Bacteriuria D001437 7 associated lipids
Stomach Diseases D013272 7 associated lipids
Chlamydia Infections D002690 7 associated lipids
Psychoses, Substance-Induced D011605 7 associated lipids
Plaque, Atherosclerotic D058226 7 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Klebsiella Infections D007710 7 associated lipids
Metaplasia D008679 7 associated lipids
Leprosy D007918 8 associated lipids
Fistula D005402 8 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Renal Insufficiency D051437 8 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Lymphadenitis D008199 8 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Cross Infection D003428 9 associated lipids
Urethritis D014526 9 associated lipids
Bacteremia D016470 9 associated lipids
Urination Disorders D014555 9 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Sinusitis D012852 9 associated lipids
Periodontal Pocket D010514 9 associated lipids
Obstetric Labor, Premature D007752 9 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Otitis Media with Effusion D010034 9 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Dermatitis, Exfoliative D003873 10 associated lipids
Hemophilia A D006467 10 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Ureteral Obstruction D014517 10 associated lipids
Dyspnea D004417 10 associated lipids
Abnormalities, Drug-Induced D000014 10 associated lipids
Osteomyelitis D010019 10 associated lipids
Hearing Disorders D006311 10 associated lipids
Neuromuscular Diseases D009468 10 associated lipids
Pancreatitis D010195 10 associated lipids
Liver Failure, Acute D017114 11 associated lipids
Shock, Septic D012772 11 associated lipids
Influenza, Human D007251 11 associated lipids
Uveitis, Anterior D014606 11 associated lipids
Exanthema D005076 11 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Wound Infection D014946 12 associated lipids
Otitis Media D010033 12 associated lipids
Skin Neoplasms D012878 12 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Endophthalmitis D009877 12 associated lipids
Abscess D000038 13 associated lipids
Leishmaniasis, Visceral D007898 13 associated lipids
Urticaria D014581 13 associated lipids
Rosacea D012393 13 associated lipids
Bradycardia D001919 13 associated lipids
Radiation Injuries D011832 14 associated lipids
Synovitis D013585 15 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Encephalitis D004660 15 associated lipids
HIV Seropositivity D006679 15 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Dermatomycoses D003881 17 associated lipids
Bronchial Spasm D001986 18 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Ischemia D007511 18 associated lipids
Peptic Ulcer D010437 19 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Tuberculosis D014376 20 associated lipids
Bacterial Infections D001424 21 associated lipids
Helicobacter Infections D016481 21 associated lipids
Myocardial Infarction D009203 21 associated lipids
Periodontitis D010518 22 associated lipids
Per page 10 20 50 100 | Total 242

PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with clarithromycin

Download all related citations
Per page 10 20 50 100 | Total 7636
Authors Title Published Journal PubMed Link
Vianna JS et al. The interplay between mutations in cagA, 23S rRNA, gyrA and drug resistance in Helicobacter pylori. 2018 Rev. Inst. Med. Trop. Sao Paulo pmid:29972462
Myojin S et al. Chronic otitis media caused by Mycobacterium abscessus spp. massiliense treated with tigecycline in a 10-year-old child. 2018 Int. J. Infect. Dis. pmid:29966711
Liou JM et al. Efficacies of Genotypic Resistance-Guided vs Empirical Therapy for Refractory Helicobacter pylori Infection. 2018 Gastroenterology pmid:29964036
Kwofie SK et al. Screening of Isocitrate Lyase for Novel Anti-Buruli Ulcer Natural Products Originating from Africa. 2018 Molecules pmid:29954088
Fiorini G et al. Pylera and sequential therapy for first-line Helicobacter pylori eradication: a culture-based study in real clinical practice. 2018 Eur J Gastroenterol Hepatol pmid:29481383
Zagari RM et al. Treatment of Helicobacter pylori infection: A clinical practice update. 2018 Eur. J. Clin. Invest. pmid:29144559
Liu DS et al. Primary antibiotic resistance of Helicobacter pylori in Chinese patients: a multiregion prospective 7-year study. 2018 Clin. Microbiol. Infect. pmid:29138101
Redondo JJ et al. A novel RT-PCR for the detection of Helicobacter pylori and identification of clarithromycin resistance mediated by mutations in the 23S rRNA gene. 2018 Diagn. Microbiol. Infect. Dis. pmid:29111147
Ullah S et al. Hydrophilically modified self-assembling α-tocopherol derivative as niosomal nanocarrier for improving clarithromycin oral bioavailability. 2018 Artif Cells Nanomed Biotechnol pmid:28541761
Cheung KS et al. Long-term proton pump inhibitors and risk of gastric cancer development after treatment for : a population-based study. 2018 Gut pmid:29089382