clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- J. Antimicrob. Chemother. (1)
- Clin. Diagn. Lab. Immunol. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Alsohaibani F et al. | Prospective trial in Saudi Arabia comparing the 14-day standard triple therapy with the 10-day sequential therapy for treatment of Helicobacter pylori infection. | Saudi J Gastroenterol | pmid:26228365 | |
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| Rajendiran S et al. | Increased protein carbonylation and decreased antioxidant status in anemic H. pylori infected patients: effect of treatment. | 2012 Jul-Aug | Saudi J Gastroenterol | pmid:22824768 |
| Hu JL et al. | Optimized high-dose amoxicillin-proton-pump inhibitor dual therapies fail to achieve high cure rates in China. | Saudi J Gastroenterol | pmid:28937021 | |
| Abadi AT et al. | High frequency of A2143G mutation in clarithromycin-resistant Helicobacter pylori isolates recovered from dyspeptic patients in Iran. | 2011 Nov-Dec | Saudi J Gastroenterol | pmid:22064338 |
| Dajani AI et al. | Do probiotics improve eradication response to Helicobacter pylori on standard triple or sequential therapy? | 2013 May-Jun | Saudi J Gastroenterol | pmid:23680708 |
| Al Majid FM | Peritonitis due to Mycobacterium fortuitum following gastric banding. | Saudi J Gastroenterol | pmid:20339182 | |
| Shokrzadeh L et al. | Antibiotic susceptibility profile of Helicobacter pylori isolated from the dyspepsia patients in Tehran, Iran. | Saudi J Gastroenterol | pmid:21727733 | |
| Hasan SR et al. | Short-duration furazolidone therapy in combination with amoxicillin, bismuth subcitrate, and omeprazole for eradication of Helicobacter pylori. | Saudi J Gastroenterol | pmid:20065568 | |
| Wang J et al. | Two-week triple therapy has a higher Helicobacter pylori eradication rate than 1-week therapy: A single-center randomized study. | Saudi J Gastroenterol | pmid:26655129 | |
| Pellicano R and Fagoonee S | One or two weeks of treatment with Helicobacter Pylori ''standard'' triple therapy in the year 2015? | Saudi J Gastroenterol | pmid:26655127 | |
| Salem EM et al. | Comparative study of Nigella Sativa and triple therapy in eradication of Helicobacter Pylori in patients with non-ulcer dyspepsia. | 2010 Jul-Sep | Saudi J Gastroenterol | pmid:20616418 |
| Bezmin Abadi AT et al. | Inefficiency of rapid urease test for confirmation of Helicobacter pylori. | Saudi J Gastroenterol | pmid:21196663 | |
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| Kimang'a AN et al. | Helicobacter pylori: prevalence and antibiotic susceptibility among Kenyans. | 2010 | S. Afr. Med. J. | pmid:20429490 |
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| Stefansson P et al. | Cefuroxime axetil versus clarithromycin in the treatment of acute maxillary sinusitis. | 1998 | Rhinology | pmid:9923060 |
| Haruna S et al. | A study of poor responders for long-term, low-dose macrolide administration for chronic sinusitis. | 2009 | Rhinology | pmid:19382498 |
| Furuya H et al. | SAPHO syndrome-like presentation of disseminated nontuberculous mycobacterial infection in a case with neutralizing anti-IFNγ autoantibody. | 2017 | Rheumatology (Oxford) | pmid:28371927 |
| Andereya S et al. | Reactive knee and ankle joint arthritis: abnormal manifestation of Legionella pneumophila. | 2004 | Rheumatol. Int. | pmid:14513269 |
| Cohen O et al. | Colchicine-clarithromycin-induced rhabdomyolysis in Familial Mediterranean Fever patients under treatment for Helicobacter pylori. | 2015 | Rheumatol. Int. | pmid:26210999 |
| Saviola G et al. | Clarithromycin in rheumatoid arthritis: the addition to methotrexate and low-dose methylprednisolone induces a significant additive value--a 24-month single-blind pilot study. | 2013 | Rheumatol. Int. | pmid:23864141 |
| Breda L et al. | Non-tuberculous mycobacterial osteomyelitis: an unusual cause of hip pain in immunocompetent children. | 2009 | Rheumatol. Int. | pmid:19156420 |
| Saviola G et al. | Clarithromycin in adult-onset Still's disease: a study of 6 cases. | 2010 | Rheumatol. Int. | pmid:20033412 |
| O'Connor MB et al. | Rituximab-induced pulmonary disease. | 2012 | Rheumatol. Int. | pmid:21892654 |
| Haj Yahia S et al. | Colchicine intoxication in familial Mediterranean fever patients using clarithromycin for the treatment of Helicobacter pylori: a series of six patients. | 2018 | Rheumatol. Int. | pmid:28975396 |
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