clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Granda MartÃn MJ et al. | [Mycoplasma-associated acute hepatitis in an adult patient without pulmonary involvement]. | Gastroenterol Hepatol | pmid:24569138 | |
Alsohaibani F et al. | Prospective trial in Saudi Arabia comparing the 14-day standard triple therapy with the 10-day sequential therapy for treatment of Helicobacter pylori infection. | Saudi J Gastroenterol | pmid:26228365 | |
Zullo A et al. | Furazolidone-based therapies for Helicobacter pylori infection: a pooled-data analysis. | Saudi J Gastroenterol | pmid:22249086 | |
Dharmalingam S et al. | Relationship of plasmid profile with the antibiotic sensitivity pattern of Helicobacter pylori isolates from peptic ulcer disease patients in Chennai. | Indian J Med Microbiol | pmid:17643038 | |
Caliskan R et al. | Antimicrobial resistance of Helicobacter pylori strains to five antibiotics, including levofloxacin, in Northwestern Turkey. | Rev. Soc. Bras. Med. Trop. | pmid:26108005 | |
Ubhayawardana NL et al. | Detection of clarithromycin-resistant Helicobacter pylori strains in a dyspeptic patient population in Sri Lanka by polymerase chain reaction-restriction fragment length polymorphism. | Indian J Med Microbiol | pmid:26068338 | |
Dzieciatkowski T et al. | Comparison of two methods used for monitoring low-copy cytomegalovirus infection in a patient with chronic myeloid leukemia after unrelated umbilical cord blood transplantation. | Arch. Immunol. Ther. Exp. (Warsz.) | pmid:17557148 | |
Kim HY et al. | Allele-specific duplex polymerase chain reaction to differentiate Mycobacterium abscessus subspecies and to detect highly clarithromycin-resistant isolates. | Indian J Med Microbiol | pmid:27514964 | |
Yang X et al. | Comparison Between Sequential Therapy and Modified Bismuth-Included Quadruple Therapy for Helicobacter pylori Eradication in Chinese Patients. | Am J Ther | pmid:25923229 | |
Karakaya G et al. | Determining safe antibiotics for drug hypersensitive patients with the alternative method of double-triple test. | Allergol Immunopathol (Madr) | pmid:19080798 | |
Araújo-Filho I et al. | Prevalence of Helicobacter pylori infection in advanced gastric carcinoma. | Arq Gastroenterol | pmid:17406757 | |
Martins GM et al. | MOLECULAR DETECTION OF CLARITHROMYCIN AND FLUOROQUINOLONES RESISTANCE IN HELICOBACTER PYLORI INFECTION, DIRECTLY APPLIED TO GASTRIC BIOPSIES, IN AN URBAN BRAZILIAN POPULATION. | Arq Gastroenterol | pmid:27305419 | |
Wani FA et al. | Antibiotic resistance in : A mutational analysis from a tertiary care hospital in Kashmir, India. | Indian J Med Microbiol | pmid:30084422 | |
Pombo Romero J et al. | [Evaluation of the pilot program of medicine dispensation in customized doses in Galicia [Spain]]. | Gac Sanit | pmid:17306181 | |
Rech TF et al. | Helicobacter pylori eradication: influence of interleukin-1beta -31 C/T polymorphism. | Braz J Infect Dis | pmid:30048609 | |
Wang B et al. | In-vitro characterisation of a novel antimicrobial agent, TNP-2092, against Helicobacter pylori clinical isolates. | Swiss Med Wkly | pmid:30044468 | |
Lage R et al. | Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease. | An Bras Dermatol | pmid:25672306 | |
Walicka M et al. | Mycoplasma pneumoniae-induced pneumonia with Stevens-Johnson syndrome of acute atypical course. | Pol. Arch. Med. Wewn. | pmid:18714743 | |
Bartnik W | Clinical aspects of Helicobacter pylori infection. | Pol. Arch. Med. Wewn. | pmid:18714738 | |
Kempen JH | Medical management of human immunodeficiency virus infection. | Indian J Ophthalmol | pmid:18711266 | |
Feng L et al. | Sequential Therapy or Standard Triple Therapy for Helicobacter pylori Infection: An Updated Systematic Review. | Am J Ther | pmid:25569598 | |
Fernández JA et al. | [The hospital faced with a prolonged Legionella outbreak]. | Gac Sanit | pmid:15324645 | |
Arora S et al. | Amoxicillin loaded chitosan-alginate polyelectrolyte complex nanoparticles as mucopenetrating delivery system for h. Pylori. | Sci Pharm | pmid:21886911 | |
Buzás GM et al. | Six regimens for the eradication of Helicobacter pylori (Hp) in duodenal ulcer patients: three consecutive trials (1995-1999). | J. Physiol. Paris | pmid:11595472 | |
Gokhale NS | Medical management approach to infectious keratitis. | Indian J Ophthalmol | pmid:18417822 | |
Asgari B et al. | HONEY-DERIVED LACTOBACILLUS RHAMNOSUS ALLEVIATES HELICOBACTER PYLORI-INDUCED GASTRO-INTESTINAL INFECTION AND GASTRIC INFLAMMATION IN C57BL/6 MICE: AN IMMUNO-HISTOLOGIC STUDY. | Arq Gastroenterol | pmid:30540092 | |
pmid:11817788 | ||||
Torpiano P and Pace D | Clinically-diagnosed Mediterranean Spotted Fever in Malta. | Travel Med Infect Dis | pmid:29462726 | |
Bermejo Vicedo T et al. | [A pharmacoeconomic study of in-hospital treatment against community-acquired pneumonia]. | Farm Hosp | pmid:15012176 | |
Cohen ND et al. | Use of Liposomal Gentamicin for Treatment of 5 Foals with Experimentally Induced Rhodococcus equi Pneumonia. | J. Vet. Intern. Med. | pmid:26692327 | |
Zhu C et al. | Prevalence and antimicrobial susceptibility of Ureaplasma urealyticum and Mycoplasma hominis in Chinese women with genital infectious diseases. | Indian J Dermatol Venereol Leprol | pmid:22565456 | |
Doorakkers E et al. | Helicobacter pylori eradication in the Swedish population. | Scand. J. Gastroenterol. | pmid:28323552 | |
Bezmin Abadi AT et al. | Inefficiency of rapid urease test for confirmation of Helicobacter pylori. | Saudi J Gastroenterol | pmid:21196663 | |
Clark SE et al. | Identification of a multidrug efflux pump in Flavobacterium johnsoniae. | Vet. Res. | pmid:19558960 | |
Pachot JI et al. | Experimental estimation of the role of P-Glycoprotein in the pharmacokinetic behaviour of telithromycin, a novel ketolide, in comparison with roxithromycin and other macrolides using the Caco-2 cell model. | J Pharm Pharm Sci | pmid:12753725 | |
Radzikowska E et al. | Clarithromycin Decreases IL-6 Concentration in Serum and BAL Fluid in Patients with Cryptogenic Organizing Pneumonia. | Adv Clin Exp Med | pmid:28028949 |