clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Choi SJ et al. | Column-switching high-performance liquid chromatographic determination of clarithromycin in human plasma with electrochemical detection. | 2001 | Talanta | pmid:18968261 |
| Li W et al. | Determination of clarithromycin in rat plasma by HPLC-UV method with pre-column derivatization. | 2007 | Talanta | pmid:19071316 |
| Vu DH et al. | Simultaneous determination of rifampicin, clarithromycin and their metabolites in dried blood spots using LC-MS/MS. | 2014 | Talanta | pmid:24607103 |
| Moayyedi P and Murphy B | Helicobacter pylori: a clinical update. | 2001 | Symp Ser Soc Appl Microbiol | pmid:11422568 |
| Kusters JG and Kuipers EJ | Antibiotic resistance of Helicobacter pylori. | 2001 | Symp Ser Soc Appl Microbiol | pmid:11422569 |
| Schulzke S et al. | Mycobacterium bohemicum--a cause of paediatric cervical lymphadenitis. | 2004 | Swiss Med Wkly | pmid:15190440 |
| Piso RJ et al. | Coverage of atypical pathogens for hospitalised patients with community-acquired pneumonia is not guided by clinical parameters. | 2013 | Swiss Med Wkly | pmid:24089030 |
| Wang B et al. | In-vitro characterisation of a novel antimicrobial agent, TNP-2092, against Helicobacter pylori clinical isolates. | Swiss Med Wkly | pmid:30044468 | |
| Soltermann A et al. | Assessment of Helicobacter pylori clarithromycin resistance mutations in archival gastric biopsy samples. | 2005 | Swiss Med Wkly | pmid:16034687 |
| Cone LA et al. | Delirium in the elderly resulting from azithromycin therapy. | 2003 | Surg Neurol | pmid:12826358 |
| Nzeako BC and Al-Namaani F | The antibacterial activity of honey on helicobacter pylori. | 2006 | Sultan Qaboos Univ Med J | pmid:21748138 |
| Lee HY et al. | Survey of methadone-drug interactions among patients of methadone maintenance treatment program in Taiwan. | 2012 | Subst Abuse Treat Prev Policy | pmid:22429858 |
| Earl AM et al. | High quality draft genome sequence of Segniliparus rugosus CDC 945(T)= (ATCC BAA-974(T)). | 2011 | Stand Genomic Sci | pmid:22675588 |
| Sikorski J et al. | Complete genome sequence of Segniliparus rotundus type strain (CDC 1076). | 2010 | Stand Genomic Sci | pmid:21304703 |
| Lotfy HM and Abdel-Monem Hagazy M | Comparative study of novel spectrophotometric methods manipulating ratio spectra: an application on pharmaceutical ternary mixture of omeprazole, tinidazole and clarithromycin. | 2012 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:22683662 |
| Ahmed S and Atia NN | Simultaneous determination of triple therapy for Helicobacter pylori in human plasma by reversed phase chromatography with online wavelength switching. | 2015 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:25459696 |
| Sadeghifard N et al. | Survey in Iran of clarithromycin resistance in Helicobacter pylori isolates by PCR-RFLP. | 2013 | Southeast Asian J. Trop. Med. Public Health | pmid:23682442 |
| Kumala W and Rani A | Patterns of Helicobacter pylori isolate resistance to fluoroquinolones, amoxicillin, clarithromycin and metronidazoles. | 2006 | Southeast Asian J. Trop. Med. Public Health | pmid:17333742 |
| Iamsawat S et al. | Multiplex PCR for detection of clarithromycin resistance and simultaneous species identification of Mycobacterium avium complex. | 2010 | Southeast Asian J. Trop. Med. Public Health | pmid:20578547 |
| Waites K et al. | In vitro activities of oral antimicrobial agents against penicillin-resistant Streptococcus pneumoniae: implications for outpatient treatment. | 1997 | South. Med. J. | pmid:9191739 |
| Krishna M and Lalmuanpuii J | Helicobacter pylori treatment. | 2005 | South. Med. J. | pmid:16351026 |
| Gurbuz AK et al. | Effect of N-acetyl cysteine on Helicobacter pylori. | 2005 | South. Med. J. | pmid:16351030 |
| Kanbay M et al. | Hyponatremia due to an additive effect of carbamazepine and clarithromycin. | 2007 | South. Med. J. | pmid:17330699 |
| Ermis F et al. | Second-line levofloxacin-based triple therapy's efficiency for Helicobacter pylori eradication in patients with peptic ulcer. | 2011 | South. Med. J. | pmid:21886067 |
| Bégué RE et al. | Effect of Helicobacter pylori eradication in the glycemia of children with type 1 diabetes: a preliminary study. | 2002 | South. Med. J. | pmid:12190218 |
| Nadir I et al. | Comparison of two different treatment protocols in Helicobacter pylori eradication. | 2011 | South. Med. J. | pmid:21206418 |
| Knower MT et al. | Clarithromycin for safe and cost-effective reduction of cyclosporine doses in lung allograft recipients. | 2000 | South. Med. J. | pmid:11095559 |
| Asnis DS et al. | Mycobacterium avium-intracellulare complex pneumonia in a non-HIV-infected individual: an increasingly recognized disease. | 1996 | South. Med. J. | pmid:8638183 |
| Demir M et al. | Clarithromycin resistance and efficacy of clarithromycin-containing triple eradication therapy for Helicobacter pylori infection in type 2 diabetes mellitus patients. | 2009 | South. Med. J. | pmid:19864973 |
| Cheng VC et al. | Two probable cases of serious drug interaction between clarithromycin and colchicine. | 2005 | South. Med. J. | pmid:16144178 |
| Randhawa K et al. | Nine-year progression of untreated pulmonary Mycobacterium szulgai infection. | 2010 | South. Med. J. | pmid:20622732 |
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| Bernstein JM and Bacheller CD | It's on the tip of my tongue. | Skinmed | pmid:16687984 | |
| Alberts JH and Boyd AS | Nocardia otitidiscaviarum: an unusual Nocardia species causing a primary lymphocutaneous infectious process in a mildly immunosuppressed patient. | 2002 Sep-Oct | Skinmed | pmid:14673241 |
| Ling KL et al. | Efficacy of a nitroimidazole containing tripletherapy regime in Singapore. | 2001 | Singapore Med J | pmid:11599627 |
| Luman W et al. | One week triple therapy for Helicobacter pylori associated duodenal ulcer disease. | 1999 | Singapore Med J | pmid:10709423 |
| Zainal Muttakin AR and Tan AM | Mycobacterium fortuitum catheter-related sepsis in acute leukaemia. | 2006 | Singapore Med J | pmid:16752025 |
| Chew CA et al. | The diagnosis and management of H. pylori infection in Singapore. | 2017 | Singapore Med J | pmid:28536725 |
| Khor CJ et al. | Recurrence of Helicobacter pylori infection and duodenal ulcer relapse, following successful eradication in an urban east Asian population. | 2000 | Singapore Med J | pmid:11256345 |
| Goh IX et al. | Cytochrome P450 drug interactions with statin therapy. | 2013 | Singapore Med J | pmid:23546024 |
| Fock KM et al. | A randomised trial of amoxycillin versus clarithromycin in combination with omeprazole for eradication of Helicobacter pylori infection in Singapore. | 2000 | Singapore Med J | pmid:11281438 |
| Mak SK et al. | A retrospective study on efficacy of proton-pump inhibitor-based triple therapy for eradication of Helicobacter pylori in patients with chronic renal failure. | 2003 | Singapore Med J | pmid:14503780 |
| Prime K and French P | Neuropsychiatric reaction induced by clarithromycin in a patient on highly active antiretroviral therapy (HAART). | 2001 | Sex Transm Infect | pmid:11463936 |
| Colebunders R and Florence E | Neuropsychiatric reaction induced by clarithromycin. | 2002 | Sex Transm Infect | pmid:11872875 |
| Zheng H et al. | Association of the in vitro susceptibility of clinical isolates of chlamydia trachomatis with serovar and duration of antibiotic exposure. | 2015 | Sex Transm Dis | pmid:25668641 |
| Abu-Khalaf N et al. | The Taste of Commercially Available Clarithromycin Oral Pharmaceutical Suspensions in the Palestinian Market: Electronic Tongue and In Vivo Evaluation. | 2018 | Sensors (Basel) | pmid:29401675 |
| Kobayashi Y et al. | Advanced taste sensors based on artificial lipids with global selectivity to basic taste qualities and high correlation to sensory scores. | 2010 | Sensors (Basel) | pmid:22319306 |
| Dimopoulos MA et al. | Treatment of Waldenstrom's macroglobulinemia with single-agent thalidomide or with the combination of clarithromycin, thalidomide and dexamethasone. | 2003 | Semin. Oncol. | pmid:12720150 |
| Coleman M et al. | Treatment of Waldenstrom's macroglobulinemia with clarithromycin, low-dose thalidomide, and dexamethasone. | 2003 | Semin. Oncol. | pmid:12720151 |
| Hoffman JS | Pharmacological therapy of Helicobacter pylori infection. | 1997 | Semin. Gastrointest. Dis. | pmid:9232728 |