clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- J. Antimicrob. Chemother. (1)
- Clin. Diagn. Lab. Immunol. (1)
- Others (2)
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Huang CC et al. | In vitro activity of aminoglycosides, clofazimine, d-cycloserine and dapsone against 83 Mycobacterium avium complex clinical isolates. | 2018 | J Microbiol Immunol Infect | pmid:28705770 |
| Tang D et al. | [Efficacy of bismuth containing quadruple therapies on Helicobacter pylori eradication in patients with history of antibiotic treatment]. | 2018 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:30124214 |
| Byeon JY et al. | Effects of genetic polymorphisms of CYP2C19 on the pharmacokinetics of zolpidem. | 2018 | Arch. Pharm. Res. | pmid:30117082 |
| Park CG et al. | Clinical relevance of point mutations in the 23S rRNA gene in Helicobacter pylori eradication: A prospective, observational study. | 2018 | Medicine (Baltimore) | pmid:30113472 |
| Morgene MF et al. | HaCaT epithelial cells as an innovative novel model of rhinovirus infection and impact of clarithromycin treatment on infection kinetics. | 2018 | Virology | pmid:30077071 |
| Shinozaki S et al. | Pre-treatment with proton pump inhibitors decreases the success of primary Helicobacter pylori eradication using a vonoprazan-based regimen. | 2018 | Kaohsiung J. Med. Sci. | pmid:30041763 |
| Iannone A et al. | New fecal test for non-invasive detection: A diagnostic accuracy study. | 2018 | World J. Gastroenterol. | pmid:30038469 |
| Heffernan CB et al. | Does Clarithromycin Cause Hearing Loss? A 12-Year Review of Clarithromycin Therapy for Nontuberculous Mycobacterial Lymphadenitis in Children. | 2018 | Ann. Otol. Rhinol. Laryngol. | pmid:30032669 |
| Hamza D et al. | Genotyping and antimicrobial resistance patterns of Helicobacter pylori in human and dogs associated with A2142G and A2143G point mutations in clarithromycin resistance. | 2018 | Microb. Pathog. | pmid:30031039 |
| Vianna JS et al. | The interplay between mutations in cagA, 23S rRNA, gyrA and drug resistance in Helicobacter pylori. | 2018 | Rev. Inst. Med. Trop. Sao Paulo | pmid:29972462 |
| Myojin S et al. | Chronic otitis media caused by Mycobacterium abscessus spp. massiliense treated with tigecycline in a 10-year-old child. | 2018 | Int. J. Infect. Dis. | pmid:29966711 |
| Liou JM et al. | Efficacies of Genotypic Resistance-Guided vs Empirical Therapy for Refractory Helicobacter pylori Infection. | 2018 | Gastroenterology | pmid:29964036 |
| Kwofie SK et al. | Screening of Isocitrate Lyase for Novel Anti-Buruli Ulcer Natural Products Originating from Africa. | 2018 | Molecules | pmid:29954088 |
| RodrÃguez-Sevilla G et al. | Influence of three-dimensional lung epithelial cells and interspecies interactions on antibiotic efficacy against Mycobacterium abscessus and Pseudomonas aeruginosa. | 2018 | Pathog Dis | pmid:29648588 |
| Namkoong H et al. | Clarithromycin expands CD11b+Gr-1+ cells via the STAT3/Bv8 axis to ameliorate lethal endotoxic shock and post-influenza bacterial pneumonia. | 2018 | PLoS Pathog. | pmid:29621339 |
| Berende A et al. | Cost-effectiveness of longer-term versus shorter-term provision of antibiotics in patients with persistent symptoms attributed to Lyme disease. | 2018 | PLoS ONE | pmid:29608590 |
| Mabe K et al. | Randomized controlled trial: PPI-based triple therapy containing metronidazole versus clarithromycin as first-line treatment for Helicobacter pylori in adolescents and young adults in Japan. | 2018 | J. Infect. Chemother. | pmid:29605555 |
| Chen SA et al. | HLA-A*02:07 Allele Associates with Clarithromycin-Induced Cutaneous Adverse Drug Reactions in Chinese Patients. | 2018 | Basic Clin. Pharmacol. Toxicol. | pmid:29575644 |
| van Dyk M et al. | Assessment of inter-racial variability in CYP3A4 activity and inducibility among healthy adult males of Caucasian and South Asian ancestries. | 2018 | Eur. J. Clin. Pharmacol. | pmid:29572563 |
| Chen J et al. | Application of next-generation sequencing to characterize novel mutations in clarithromycin-susceptible Helicobacter pylori strains with A2143G of 23S rRNA gene. | 2018 | Ann. Clin. Microbiol. Antimicrob. | pmid:29562911 |
| RodrÃguez-Sevilla G et al. | Non-Tuberculous Mycobacteria multispecies biofilms in cystic fibrosis: development of an in vitro Mycobacterium abscessus and Pseudomonas aeruginosa dual species biofilm model. | 2018 | Int. J. Med. Microbiol. | pmid:29555180 |
| Leung WK et al. | Effects of Helicobacter pylori Treatment on Incidence of Gastric Cancer in Older Individuals. | 2018 | Gastroenterology | pmid:29550592 |
| Kusuki M et al. | Determination of the antimicrobial susceptibility and molecular profile of clarithromycin resistance in the Mycobacterium abscessus complex in Japan by variable number tandem repeat analysis. | 2018 | Diagn. Microbiol. Infect. Dis. | pmid:29550059 |
| Brennan DE et al. | Can bacterial virulence factors predict antibiotic resistant infection? | 2018 | World J. Gastroenterol. | pmid:29531461 |
| Reisfeld L et al. | Cutaneous mycobacteriosis in a captive Amazonian manatee Trichechus inunguis. | 2018 | Dis. Aquat. Org. | pmid:29516862 |
| Fiorini G et al. | Pylera and sequential therapy for first-line Helicobacter pylori eradication: a culture-based study in real clinical practice. | 2018 | Eur J Gastroenterol Hepatol | pmid:29481383 |
| Aderemi AO et al. | Oxidative stress responses and cellular energy allocation changes in microalgae following exposure to widely used human antibiotics. | 2018 | Aquat. Toxicol. | pmid:30125766 |
| Nakase K et al. | Long-term administration of oral macrolides for acne treatment increases macrolide-resistant Propionibacterium acnes. | 2018 | J. Dermatol. | pmid:29235673 |
| Cho EH et al. | Differences in drug susceptibility pattern between Mycobacterium avium and Mycobacterium intracellulare isolated in respiratory specimens. | 2018 | J. Infect. Chemother. | pmid:29223615 |
| Compain F et al. | In vitro activity of tedizolid against the Mycobacterium abscessus complex. | 2018 | Diagn. Microbiol. Infect. Dis. | pmid:29217419 |
| Li H et al. | Inappropriate treatment in Helicobacter pylori eradication failure: a retrospective study. | 2018 | Scand. J. Gastroenterol. | pmid:29214879 |
| Jung JH et al. | Clinical Outcomes of Standard Triple Therapy Plus Probiotics or Concomitant Therapy for Infection. | 2018 | Gut Liver | pmid:29212313 |
| Deng J et al. | Lack of additional effects of long-term, low-dose clarithromycin combined treatment compared with topical steroids alone for chronic rhinosinusitis in China: a randomized, controlled trial. | 2018 | Int Forum Allergy Rhinol | pmid:29195025 |
| Beer-Davidson G et al. | Detection of Helicobacter pylori in stool samples of young children using real-time polymerase chain reaction. | 2018 | Helicobacter | pmid:29181860 |
| Muñoz-Gómez P et al. | Macrolide use in the previous years is associated with failure to eradicate Helicobacter pylori with clarithromycin-containing regimens. | 2018 | Helicobacter | pmid:29178562 |
| Zagari RM et al. | Treatment of Helicobacter pylori infection: A clinical practice update. | 2018 | Eur. J. Clin. Invest. | pmid:29144559 |
| Liu DS et al. | Primary antibiotic resistance of Helicobacter pylori in Chinese patients: a multiregion prospective 7-year study. | 2018 | Clin. Microbiol. Infect. | pmid:29138101 |
| Redondo JJ et al. | A novel RT-PCR for the detection of Helicobacter pylori and identification of clarithromycin resistance mediated by mutations in the 23S rRNA gene. | 2018 | Diagn. Microbiol. Infect. Dis. | pmid:29111147 |
| De Lorenzi G et al. | Mycobacterium genavense Infection in a Domestic Ferret (Mustela putorius furo). | 2018 | Top Companion Anim Med | pmid:30502861 |
| McNicholl AG et al. | Probiotic supplementation with Lactobacillus plantarum and Pediococcus acidilactici for Helicobacter pylori therapy: A randomized, double-blind, placebo-controlled trial. | 2018 | Helicobacter | pmid:30141228 |
| Silva GM et al. | Helicobacter pylori antimicrobial resistance in a pediatric population. | 2018 | Helicobacter | pmid:30091503 |
| Mahachai V et al. | Helicobacter pylori management in ASEAN: The Bangkok consensus report. | 2018 | J. Gastroenterol. Hepatol. | pmid:28762251 |
| Bilgilier C et al. | Prospective multicentre clinical study on inter- and intrapatient genetic variability for antimicrobial resistance of Helicobacter pylori. | 2018 | Clin. Microbiol. Infect. | pmid:28669844 |
| Barros S et al. | Cat Scratch Disease: Not a Benign Condition. | 2018 | Ocul. Immunol. Inflamm. | pmid:28665750 |
| Ullah S et al. | Hydrophilically modified self-assembling α-tocopherol derivative as niosomal nanocarrier for improving clarithromycin oral bioavailability. | 2018 | Artif Cells Nanomed Biotechnol | pmid:28541761 |
| Yoshida S et al. | Association between sequevar and antibiotic treatment outcome in patients with Mycobacterium abscessus complex infections in Japan. | 2018 | J. Med. Microbiol. | pmid:29227218 |
| Cheung KS et al. | Long-term proton pump inhibitors and risk of gastric cancer development after treatment for : a population-based study. | 2018 | Gut | pmid:29089382 |
| Choi IJ et al. | Helicobacter pylori Therapy for the Prevention of Metachronous Gastric Cancer. | 2018 | N. Engl. J. Med. | pmid:29562147 |
| Ribaldone DG et al. | Helicobacter pylori eradication: poor medical compliance from East to West of the world. | 2018 | Scand. J. Gastroenterol. | pmid:29383955 |
| Suzuki K et al. | Clinical significance and epidemiologic analyses of Mycobacterium avium and Mycobacterium intracellulare lung disease from post-marketing surveillance. | 2018 | Respir Investig | pmid:29325687 |