clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kelly C et al. | Macrolide antibiotics for bronchiectasis. | 2018 | Cochrane Database Syst Rev | pmid:29543980 |
Mégraud F | Antibiotic Resistance Is the Key Element in Treatment of Helicobacter pylori Infection. | 2018 | Gastroenterology | pmid:30308190 |
Mieras LF et al. | An enhanced regimen as post-exposure chemoprophylaxis for leprosy: PEP+. | 2018 | BMC Infect. Dis. | pmid:30290790 |
Liou JM et al. | Toward population specific and personalized treatment of Helicobacter pylori infection. | 2018 | J. Biomed. Sci. | pmid:30285834 |
Liu HY et al. | Bilateral Non-tuberculous Mycobacterial Keratitis After Small Incision Lenticule Extraction. | 2018 | J Refract Surg | pmid:30199569 |
Kabakambira JD et al. | Efficacy of Helicobacter pylori eradication regimens in Rwanda: a randomized controlled trial. | 2018 | BMC Gastroenterol | pmid:30165823 |
Yotsu RR et al. | Drugs for treating Buruli ulcer (Mycobacterium ulcerans disease). | 2018 | Cochrane Database Syst Rev | pmid:30136733 |
Abu-Khalaf N et al. | The Taste of Commercially Available Clarithromycin Oral Pharmaceutical Suspensions in the Palestinian Market: Electronic Tongue and In Vivo Evaluation. | 2018 | Sensors (Basel) | pmid:29401675 |
Chai KY et al. | Roxithromycin monotherapy inducing a partial response in a patient with myeloma: a case report. | 2018 | J Med Case Rep | pmid:29743095 |
Strouvalis I et al. | Early increase of VEGF-A is associated with resolution of ventilator-associated pneumonia: Clinical and experimental evidence. | 2018 | Respirology | pmid:29741298 |
Long X et al. | Bismuth improves efficacy of proton-pump inhibitor clarithromycin, metronidazole triple Helicobacter pylori therapy despite a high prevalence of antimicrobial resistance. | 2018 | Helicobacter | pmid:29696736 |
Fiorini G et al. | Antibiotic resistance pattern of Helicobacter pylori strains isolated in Italy during 2010-2016. | 2018 | Scand. J. Gastroenterol. | pmid:29688095 |
Matta AJ et al. | Punctual mutations in gene of clarithromycin-resistant in Colombian populations. | 2018 | World J. Gastroenterol. | pmid:29662291 |
Wang YH et al. | A systematic review and meta-analysis of genotypic methods for detecting antibiotic resistance in Helicobacter pylori. | 2018 | Helicobacter | pmid:29405526 |
Tso S et al. | Clarithromycin as a steroid sparing agent for the management of infantile bullous pemphigoid. | 2018 | BMJ Case Rep | pmid:29374651 |
Sahara S et al. | Efficacy of Reduced Dosage of Amoxicillin in an Eradication Therapy for Helicobacter pylori Infection in Patients on Hemodialysis: A Randomized Controlled Trial. | 2018 | Digestion | pmid:29310119 |
Marsousi N et al. | Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software. | 2018 | Biopharm Drug Dispos | pmid:28960401 |
Popovic V et al. | Mycobacterium shimoidei-cavitary pulmonary disease with favorable outcome. | 2018 | Folia Microbiol. (Praha) | pmid:28913757 |
Hosono Y et al. | The association between erythromycin monotherapy for Mycobacterium avium complex lung disease and cross-resistance to clarithromycin: A retrospective case-series study. | 2018 | J. Infect. Chemother. | pmid:29361415 |
Alenezi A et al. | Controlled release of clarithromycin from PLGA microspheres enhances bone regeneration in rabbit calvaria defects. | 2018 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:28067984 |