clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Stomach Diseases D013272 7 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Skin Neoplasms D012878 12 associated lipids
Colitis D003092 69 associated lipids
Leishmaniasis, Visceral D007898 13 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Per page 10 20 50 100 | Total 7636
Authors Title Published Journal PubMed Link
Sugihara J et al. [Efficacy of clarithromycin on chronic paranasal sinusitis--a comparison between children and adult]. 1997 Jpn J Antibiot pmid:9597431
Hamada K et al. [Evaluation of antineoplastic effect of CAM (clarithromycin) in a mouse model inoculated with lung cancer cells]. 1997 Jpn J Antibiot pmid:9597434
Kokubo Y et al. [Effects of clarithromycin on experimental pulmonary metastasis]. 1997 Jpn J Antibiot pmid:9597436
Sakamoto M et al. [Efficacy of clarithromycin on cancer cachexia in patients with primary non-small cell lung cancer]. 1997 Jpn J Antibiot pmid:9597437
Teramoto S et al. [Fluctuation in the cytokine m-RNA content in primary non-small cell lung cancer caused by clarithromycin (CAM) administration]. 1997 Jpn J Antibiot pmid:9597438
Mikasa K et al. [Effect of clarithromycin on prolonging the life expectancy of patients with primary lung cancer]. 1997 Jpn J Antibiot pmid:9597439
Takeda H et al. [Macrolide antibiotic actions on bacteria and cultured airway cells]. 1997 Jpn J Antibiot pmid:9597448
Mita Y et al. [Vitamin D3 induction of differentiation of HL-60 cells to monocyte- like cells and their aggregation--a dynamic culture method and clarithromycin]. 1997 Jpn J Antibiot pmid:9597462
Yanagihara K et al. [Analysis of chronic respiratory tract infection by using an intubation model--evaluation based on fluctuations in cytokine content]. 1997 Jpn J Antibiot pmid:9597463
Konishi M et al. [Log-term administration of clarithromycin as a possible adjuvant therapy of HIV infections]. 1997 Jpn J Antibiot pmid:9597467
Iino Y et al. [Immunohistochemical study of the paranasal sinus mucosa of patients being treated with macrolide antibiotics--effects of antigen-presenting cells on the expression of a costimulator]. 1998 Jpn J Antibiot pmid:9597477
Salgado CG et al. [Study on the effects of macrolide antibiotics on the expression of B7-1, B7-2, and CD40 on epidermal Langerhans cells]. 1998 Jpn J Antibiot pmid:9597478
Isono K et al. [Effects of macrolide antibiotics on neutrophil infiltration into the airway mucosa and ICAM-1 expression]. 1998 Jpn J Antibiot pmid:9597480
Enomoto F et al. [Changes in adhesion molecule expressions in neutrophils caused by new macrolide administration]. 1998 Jpn J Antibiot pmid:9597482
Ieshiro R et al. [Effect of clarithromycin in extending the life expectancy of patients with non-small-cell lung cancer--the second report]. 1998 Jpn J Antibiot pmid:9597484
Sakamoto M et al. [Efficacy of clarithromycin (CAM) in patients with inoperable non-small-cell lung cancer]. 1998 Jpn J Antibiot pmid:9597485
Teramoto S et al. [Effect of clarithromycin administration on interferon-gamma and interleukin 12 mRNA expression in the tumor tissue of non-small-cell lung cancer]. 1998 Jpn J Antibiot pmid:9597486
Ueta K et al. [Evaluation of BRM (biological response modifier) action of clarithromycin (CAM)--effect on cytokine expression in a mouse lung cancer model]. 1998 Jpn J Antibiot pmid:9597487
Kokubo Y et al. [Effect of clarithromycin on experimental pulmonary metastasis]. 1998 Jpn J Antibiot pmid:9597488
Yano S et al. [Significance of therapeutic efficacy of clarithromycin in a model for human lung cancer metastasis and a mouse tumor system]. 1998 Jpn J Antibiot pmid:9597491
Sasa K et al. [Antineoplastic therapeutic effect of clarithromycin in rats]. 1998 Jpn J Antibiot pmid:9597492
Miyamoto N et al. [Test to set dosages for long-term administration of clarithromycin to treat chronic paranasal sinusitis]. 1998 Jpn J Antibiot pmid:9597498
Fujita K et al. [Neutrophil count and IL-8 level of nasal secretion of patients with chronic paranasal sinusitis and the effects of macrolide antibiotics]. 1998 Jpn J Antibiot pmid:9597505
Harris A Current regimens for treatment of Helicobacter pylori infection. 1998 Br. Med. Bull. pmid:9604443
Doherty TM and Sher A IL-12 promotes drug-induced clearance of Mycobacterium avium infection in mice. 1998 J. Immunol. pmid:9605144
Moayyedi P et al. Relevance of antibiotic sensitivities in predicting failure of omeprazole, clarithromycin, and tinidazole to eradicate Helicobacter pylori. 1998 J. Gastroenterol. pmid:9605943
Gavura SR and Nusinowitz S Leukocytoclastic vasculitis associated with clarithromycin. 1998 Ann Pharmacother pmid:9606474
Ramon PM et al. [Uveitis, arthralgia and pseudo-jaundice in a HIV seronegative patient due to rifabutin]. 1998 Rev Mal Respir pmid:9608993
Lilley LL and Guanci R A dangerous combination. 1998 Am J Nurs pmid:9612423
Fischer BP et al. [Tsutsugamushi fever. Rare rickettsiosis after a stay in the Philippines]. 1998 Dtsch. Med. Wochenschr. pmid:9615696
Torresani C Clarithromycin: a new perspective in rosacea treatment. 1998 Int. J. Dermatol. pmid:9620480
Kruppa A et al. Immediate reaction to roxithromycin and prick test cross-sensitization to erythromycin and clarithromycin. 1998 Dermatology (Basel) pmid:9621142
Tsuneoka H et al. [Sensitivity of Helicobacter pylori to amoxicillin and clarythromycin with special reference to eradication therapy]. 1998 Kansenshogaku Zasshi pmid:9621560
Roussel G and Igual J Clarithromycin with minocycline and clofazimine for Mycobacterium avium intracellulare complex lung disease in patients without the acquired immune deficiency syndrome. GETIM. Groupe d'Etude et de Traitement des Infections à Mycobactéries. 1998 Int. J. Tuberc. Lung Dis. pmid:9626603
Archimandritis A et al. Clostridium difficile colitis associated with a 'triple' regimen, containing clarithromycin and metronidazole, to eradicate Helicobacter pylori. 1998 J. Intern. Med. pmid:9627163
Petersen AM et al. [Resistance of Helicobacter pylori to clarithomycin]. 1998 Ugeskr. Laeg. pmid:9627511
Domingo D et al. High frequency of mutations at position 2144 of the 23S rRNA gene in clarithromycin-resistant Helicobacter pylori strains isolated in Spain. 1998 J. Antimicrob. Chemother. pmid:9630414
Fireman Z et al. Helicobacter pylori and peptic ulcer disease therapies: a survey of gastroenterologists in Israel. 1998 Helicobacter pmid:9631306
Battaglia G et al. Optimal PPI-based triple therapy for the cure of Helicobacter pylori infection: a single center comparison of four 14-day schedules. 1998 Helicobacter pmid:9631310
Miwa H et al. Effectiveness of omeprazole-amoxicillin-clarithromycin (OAC) therapy for Helicobacter pylori infection in a Japanese population. 1998 Helicobacter pmid:9631313
Calvet Calvo X [Treatment of Helicobacter pylori infections]. 1998 Gastroenterol Hepatol pmid:9633184
Burman WJ et al. AIDS-related Mycobacterium kansasii infection with initial resistance to clarithromycin. 1998 Diagn. Microbiol. Infect. Dis. pmid:9635911
Nordt SP et al. Clarithromycin induced digoxin toxicity. 1998 J Accid Emerg Med pmid:9639187
Gray VS Syncopal episodes associated with cisapride and concurrent drugs. 1998 Ann Pharmacother pmid:9640482
Grove DI et al. Comparison of culture, histopathology and urease testing for the diagnosis of Helicobacter pylori gastritis and susceptibility to amoxycillin, clarithromycin, metronidazole and tetracycline. 1998 Pathology pmid:9643503
Makhani S et al. Atypical cervico-facial mycobacterial infections in childhood. 1998 Br J Oral Maxillofac Surg pmid:9643597
Wharton JR et al. Erythrasma treated with single-dose clarithromycin. 1998 Arch Dermatol pmid:9645634
Shimoyama T et al. [Antibiotic therapy in eradicating Helicobacter pylori infections]. 1998 Nippon Naika Gakkai Zasshi pmid:9648426
Kimura K and Sato K [Recent topics on Helicobacter pylori--Historic background and problems caused by bacteria]. 1998 Nippon Naika Gakkai Zasshi pmid:9648427
Aoyama N [Efficacy of antibiotic therapy in eradicating Helicobacter pylori]. 1998 Nippon Naika Gakkai Zasshi pmid:9648439