| MeSH term | MeSH ID | Detail |
|---|---|---|
| Bacterial Infections | D001424 | 21 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Stomach Diseases | D013272 | 7 associated lipids |
| Lung Diseases | D008171 | 37 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Skin Neoplasms | D012878 | 12 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Leishmaniasis, Visceral | D007898 | 13 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tanaka H et al. | Effect of clarithromycin on steady-state digoxin concentrations. | 2003 | Ann Pharmacother | pmid:12549942 |
| Soriano F and Rodriguez-Cerrato V | Pharmacodynamic and kinetic basis for the selection of pneumococcal resistance in the upper respiratory tract. | 2002 | J. Antimicrob. Chemother. | pmid:12556434 |
| [Patient with increased stomach cancer risk. Helicobacter can cause damage here]. | 2002 | MMW Fortschr Med | pmid:12557832 | |
| Johnson DA | Review of esomeprazole in the treatment of acid disorders. | 2003 | Expert Opin Pharmacother | pmid:12562316 |
| Loughlin MF et al. | Monotherapy with mastic does not eradicate Helicobacter pylori infection from mice. | 2003 | J. Antimicrob. Chemother. | pmid:12562704 |
| Torres A et al. | Effectiveness of oral moxifloxacin in standard first-line therapy in community-acquired pneumonia. | 2003 | Eur. Respir. J. | pmid:12570122 |
| Doucet-Populaire F et al. | Natural and acquired macrolide resistance in mycobacteria. | 2002 | Curr Drug Targets Infect Disord | pmid:12570741 |
| Woods GL et al. | Multisite reproducibility of results obtained by two broth dilution methods for susceptibility testing of Mycobacterium avium complex. | 2003 | J. Clin. Microbiol. | pmid:12574258 |
| Rüssmann H et al. | Detection of Helicobacter pylori in paraffin-embedded and in shock-frozen gastric biopsy samples by fluorescent in situ hybridization. | 2003 | J. Clin. Microbiol. | pmid:12574289 |
| Matsumoto R et al. | [Case of pulmonary MALT lymphoma successfully treated with clarithromycin]. | 2001 | Jpn J Antibiot | pmid:12575409 |
| Hori S et al. | [Effect of clarithromycin on lipopolysaccharide-induced anorexia]. | 2001 | Jpn J Antibiot | pmid:12575411 |
| Iino Y | [Efficacy of macrolide therapy for children with serous otitis media]. | 2001 | Jpn J Antibiot | pmid:12575412 |
| Ichiyama T et al. | [Inhibitory effect of clarithromycin on NF-kappaB activation]. | 2001 | Jpn J Antibiot | pmid:12575416 |
| Ushigai M et al. | [Effects of clarithromycin on cytokine expression and NF-kappaB activation in nasal-mucosa derived cultured cells]. | 2001 | Jpn J Antibiot | pmid:12575417 |
| Hashiba M et al. | [Effect of macrolide therapy on microbes in nasal cavity and larynx of patients with chronic paranasal sinusitis]. | 2001 | Jpn J Antibiot | pmid:12575431 |
| Sauter C and Blum S | Regression of lung lesions in Hodgkin's disease by antibiotics: case report and hypothesis on the etiology of Hodgkin's disease. | 2003 | Am. J. Clin. Oncol. | pmid:12576932 |
| Bodasing N and Kennedy D | Moraxella catarrhalis bacteraemia associated with Mycoplasma pneumoniae infection and pneumonia. | 2002 | Scand. J. Infect. Dis. | pmid:12578160 |
| Freitas D et al. | An outbreak of Mycobacterium chelonae infection after LASIK. | 2003 | Ophthalmology | pmid:12578767 |
| Weiss K and Vanjaka A | An open-label, randomized, multicenter, comparative study of the efficacy and safety of 7 days of treatment with clarithromycin extended-release tablets versus clarithromycin immediate-release tablets for the treatment of patients with acute bacterial exacerbation of chronic bronchitis. | 2002 | Clin Ther | pmid:12581548 |
| Einarson TR et al. | An examination of the effect of cytochrome P450 drug interactions of hydroxymethylglutaryl-coenzyme A reductase inhibitors on health care utilization: a Canadian population-based study. | 2002 | Clin Ther | pmid:12581550 |
| Esteban J et al. | A comparison between disk diffusion and microdilution for susceptibility testing of Mycobacterium fortuitum complex. | 2002 | J Chemother | pmid:12583544 |
| Novelli A et al. | In vivo pharmacodynamic evaluation of clarithromycin in comparison to erythromycin. | 2002 | J Chemother | pmid:12583550 |
| Romanelli G et al. | Carbapenems in the treatment of severe community-acquired pneumonia in hospitalized elderly patients: a comparative study against standard therapy. | 2002 | J Chemother | pmid:12583553 |
| Fujiuchi S et al. | Analysis of chest CT in patients with Mycobacterium avium complex pulmonary disease. | 2003 Jan-Feb | Respiration | pmid:12584395 |
| Latorre C and Sanfeliu I | [Haemophilus influenzae: phenotype characteristics of strains isolated in 12 Catalan hospitals over one year]. | 2003 | Enferm. Infecc. Microbiol. Clin. | pmid:12586016 |
| Aracil B et al. | [Sensitivity of Haemophilus influenzae isolates in Spain to 17 oral antibiotics]. | 2003 | Enferm. Infecc. Microbiol. Clin. | pmid:12586017 |
| Toro C et al. | [Association among anti-CagA antibody detection, antibiotic susceptibility, and peptic ulcer in patients with Helicobacter pylori infection]. | 2003 | Enferm. Infecc. Microbiol. Clin. | pmid:12586018 |
| Curtis LH et al. | Prescription of QT-prolonging drugs in a cohort of about 5 million outpatients. | 2003 | Am. J. Med. | pmid:12586234 |
| Petersen JP et al. | Community outbreak of perianal group A streptococcal infection in Denmark. | 2003 | Pediatr. Infect. Dis. J. | pmid:12586971 |
| Baughman AL and Bisgard KM | Need for equivalence testing of efficacy of alternative antibiotics for treatment of pertussis. | 2003 | Pediatr. Infect. Dis. J. | pmid:12586986 |
| Alarcón T et al. | [In vitro activity of clarithromycin and metronidazole against Helicobacter pylori in different incubation atmospheres]. | 2002 | Rev Esp Quimioter | pmid:12587039 |
| Burkhardt O et al. | Single- and multiple-dose pharmacokinetics of oral moxifloxacin and clarithromycin, and concentrations in serum, saliva and faeces. | 2002 | Scand. J. Infect. Dis. | pmid:12587622 |
| Rozynek E et al. | Primary resistance of Helicobacter pylori to antimicrobial agents in Polish children. | 2002 | Acta Microbiol. Pol. | pmid:12588100 |
| Rassiat E et al. | [Acute pancreatitis after clarithromycin and beta-methasone]. | 2003 | Gastroenterol. Clin. Biol. | pmid:12594377 |
| Severe colchicine-macrolide interactions. | 2003 | Prescrire Int | pmid:12602385 | |
| Orr CF and Rowe DB | Helicobacter pylori hiccup. | 2003 | Intern Med J | pmid:12603589 |
| Mohammadi M et al. | Clarithromycin resistance in Iranian H. pylori strains before introduction of clarithromycin. | 2003 | Helicobacter | pmid:12603622 |
| Stein CR et al. | Using hospital antibiogram data to assess regional pneumococcal resistance to antibiotics. | 2003 | Emerging Infect. Dis. | pmid:12603992 |
| Peric M et al. | Effects of an efflux mechanism and ribosomal mutations on macrolide susceptibility of Haemophilus influenzae clinical isolates. | 2003 | Antimicrob. Agents Chemother. | pmid:12604536 |
| Dupont C et al. | Helicobacter pylori and antimicrobial susceptibility in children. | 2003 | J. Pediatr. Gastroenterol. Nutr. | pmid:12604967 |
| Crone J et al. | Helicobacter pylori in children and adolescents: increase of primary clarithromycin resistance, 1997-2000. | 2003 | J. Pediatr. Gastroenterol. Nutr. | pmid:12604976 |
| Gościniak G et al. | Helicobacter pylori antigens in stool specimens of gastritis children before and after treatment. | 2003 | J. Pediatr. Gastroenterol. Nutr. | pmid:12604978 |
| Dinos GP et al. | Erythromycin, roxithromycin, and clarithromycin: use of slow-binding kinetics to compare their in vitro interaction with a bacterial ribosomal complex active in peptide bond formation. | 2003 | Mol. Pharmacol. | pmid:12606769 |
| Satoh K | [New triple therapy for Helicobacter pylori infection in Japan]. | 2003 | Nippon Rinsho | pmid:12607326 |
| Tanaka G et al. | [Mycoplasma pneumonia of identical twin sisters with different clinical courses depending on the treatment]. | 2002 | Kansenshogaku Zasshi | pmid:12607352 |
| Scheinfeld NS et al. | Macrolides in dermatology. | 2003 Jan-Feb | Clin. Dermatol. | pmid:12609587 |
| Montague ML et al. | Three cases of atypical mycobacterial cervical adenitis. | 2003 | J R Soc Med | pmid:12612115 |
| Arima N and Tsudo M | Extragastric mucosa-associated lymphoid tissue lymphoma showing the regression by Helicobacter pylori eradication therapy. | 2003 | Br. J. Haematol. | pmid:12614211 |
| Van Kerkhoven D et al. | Breakthrough pneumococcal bacteraemia in patients treated with clarithromycin or oral beta-lactams. | 2003 | J. Antimicrob. Chemother. | pmid:12615872 |
| Guchev IA et al. | [Evaluation of clarithromycin efficacy in the treatment of community-acquired pneumonia on the basis of the Binax NOW test results (a prospective open trial)]. | 2002 | Antibiot. Khimioter. | pmid:12619516 |
| Chatterjee A et al. | The bactericidal effects of Lactobacillus acidophilus, garcinol and Protykin compared to clarithromycin, on Helicobacter pylori. | 2003 | Mol. Cell. Biochem. | pmid:12619886 |
| Miyashita N et al. | Chlamydia pneumoniae infection in adult patients with persistent cough. | 2003 | J. Med. Microbiol. | pmid:12621093 |
| Démolis JL et al. | Effect of single and repeated oral doses of telithromycin on cardiac QT interval in healthy subjects. | 2003 | Clin. Pharmacol. Ther. | pmid:12621389 |
| Lohitnavy M et al. | Pharmacokinetic and bloequivalence studies of generic clarithromycin tablets in healthy male volunteers. | 2003 | Pharmazie | pmid:12622260 |
| Mandell DL et al. | Management of nontuberculous mycobacterial cervical lymphadenitis. | 2003 | Arch. Otolaryngol. Head Neck Surg. | pmid:12622546 |
| Wong WM et al. | Randomized controlled study of rabeprazole, levofloxacin and rifabutin triple therapy vs. quadruple therapy as second-line treatment for Helicobacter pylori infection. | 2003 | Aliment. Pharmacol. Ther. | pmid:12622764 |
| Wang WH et al. | Aspirin inhibits the growth of Helicobacter pylori and enhances its susceptibility to antimicrobial agents. | 2003 | Gut | pmid:12631656 |
| Witt A et al. | Placental passage of clarithromycin surpasses other macrolide antibiotics. | 2003 | Am. J. Obstet. Gynecol. | pmid:12634663 |
| Peric M et al. | Activity of nine oral agents against gram-positive and gram-negative bacteria encountered in community-acquired infections: use of pharmacokinetic/pharmacodynamic breakpoints in the comparative assessment of beta-lactam and macrolide antimicrobial agents. | 2003 | Clin Ther | pmid:12637118 |
| Odagiri S et al. | [Epidemiological study on patients with pneumococcal respiratory tract infection in a Japanese health facility during the past year]. | 2001 | Jpn J Antibiot | pmid:12638138 |
| Gisbert JP et al. | Systematic review: Rabeprazole-based therapies in Helicobacter pylori eradication. | 2003 | Aliment. Pharmacol. Ther. | pmid:12641497 |
| Lai KC et al. | Effect of treatment of Helicobacter pylori on the prevention of gastroduodenal ulcers in patients receiving long-term NSAIDs: a double-blind, placebo-controlled trial. | 2003 | Aliment. Pharmacol. Ther. | pmid:12641502 |
| Zullo A et al. | High eradication rates of Helicobacter pylori with a new sequential treatment. | 2003 | Aliment. Pharmacol. Ther. | pmid:12641522 |
| Piersimoni C et al. | Mycobacterium celatum pulmonary infection in the immunocompetent: case report and review. | 2003 | Emerging Infect. Dis. | pmid:12643843 |
| Konturek PC et al. | Gene expression of ornithine decarboxylase, cyclooxygenase-2, and gastrin in atrophic gastric mucosa infected with Helicobacter pylori before and after eradication therapy. | 2003 | Dig. Dis. Sci. | pmid:12645788 |
| Kirika NV et al. | [Clinical efficacy of combined anti-Helicobacter treatment of patients with duodenal ulcer]. | 2003 | Klin Med (Mosk) | pmid:12650094 |
| Laine L et al. | Bismuth-based quadruple therapy using a single capsule of bismuth biskalcitrate, metronidazole, and tetracycline given with omeprazole versus omeprazole, amoxicillin, and clarithromycin for eradication of Helicobacter pylori in duodenal ulcer patients: a prospective, randomized, multicenter, North American trial. | 2003 | Am. J. Gastroenterol. | pmid:12650788 |
| Yamaguchi S et al. | [Clarithromycin-induced torsades de pointes]. | 2003 | Nippon Naika Gakkai Zasshi | pmid:12652715 |
| [Fluoroquinolone superior to macrolide. Longer infection free period after acute bronchitis]. | 2003 | MMW Fortschr Med | pmid:12652830 | |
| Dietrich U et al. | Ocular manifestation of disseminated Mycobacterium simiae infection in a cat. | 2003 | J Small Anim Pract | pmid:12653327 |
| Shimizu T et al. | [Effects of antisense oligo DNA on the antimicrobial activity of reactive oxygen intermediates and antimycobacterial agents against Mycobacterium avium complex]. | 2003 | Kekkaku | pmid:12655704 |
| Furuhata M et al. | Combined effect of clarithromycin and imipenem/cilastatin against urinary biofilm infection after pyeloplasty. | 2003 | Int. J. Urol. | pmid:12657103 |
| Gluais P et al. | Comparative effects of clarithromycin on action potential and ionic currents from rabbit isolated atrial and ventricular myocytes. | 2003 | J. Cardiovasc. Pharmacol. | pmid:12658051 |
| Cvetkovic RS and Goa KL | Lopinavir/ritonavir: a review of its use in the management of HIV infection. | 2003 | Drugs | pmid:12662125 |
| Gisbert JP et al. | 'Rescue' therapy with rifabutin after multiple Helicobacter pylori treatment failures. | 2003 | Helicobacter | pmid:12662375 |
| Isomoto H et al. | Lafutidine, a novel histamine H2-receptor antagonist, vs lansoprazole in combination with amoxicillin and clarithromycin for eradication of Helicobacter pylori. | 2003 | Helicobacter | pmid:12662378 |
| Steinman MA et al. | Changing use of antibiotics in community-based outpatient practice, 1991-1999. | 2003 | Ann. Intern. Med. | pmid:12667022 |
| Juurlink DN et al. | Drug-drug interactions among elderly patients hospitalized for drug toxicity. | 2003 | JAMA | pmid:12672733 |
| Kobashi Y and Matsushima T | Clinical analysis of pulmonary Mycobacterium avium complex disease in association with corticosteroid treatment. | 2003 | J. Infect. Chemother. | pmid:12673411 |
| Karlstadt RG and Walker K | Update on prescribing information for pantoprazole. | 2003 | Am Fam Physician | pmid:12674447 |
| Gal E et al. | 13C-urea breath test to validate eradication of Helicobacter pylori in an Israeli population. | 2003 | Isr. Med. Assoc. J. | pmid:12674657 |
| Mensa J et al. | [Macrolides, ketolides and streptogramins]. | 2003 | Enferm. Infecc. Microbiol. Clin. | pmid:12681133 |
| Hamdan II | Comparative in vitro investigations of the interaction between some macrolides and Cu(II), Zn(II) and Fe(II). | 2003 | Pharmazie | pmid:12685822 |
| Coleman M et al. | BLT-D (clarithromycin [Biaxin], low-dose thalidomide, and dexamethasone) for the treatment of myeloma and Waldenström's macroglobulinemia. | 2002 | Leuk. Lymphoma | pmid:12685831 |
| Sasaki M et al. | [A case of pneumonia due to coinfection by Mycoplasma pneumoniae and Chlamydia pneumoniae]. | 2002 | Nihon Kokyuki Gakkai Zasshi | pmid:12692948 |
| Hawkey CJ et al. | Safety and efficacy of 7-day rabeprazole- and omeprazole-based triple therapy regimens for the eradication of Helicobacter pylori in patients with documented peptic ulcer disease. | 2003 | Aliment. Pharmacol. Ther. | pmid:12694089 |
| Malcolm C and Marrie TJ | Antibiotic therapy for ambulatory patients with community-acquired pneumonia in an emergency department setting. | 2003 | Arch. Intern. Med. | pmid:12695270 |
| Numazaki K et al. | Chlamydia trachomatis infection in early neonatal period. | 2003 | BMC Infect. Dis. | pmid:12697048 |
| Dupas JL | [First line therapy for Helicobacter pylori eradication in France]. | 2003 | Gastroenterol. Clin. Biol. | pmid:12700504 |
| Bruley des Varannes S | [How to treat after Helicobacter pylori eradication failure?]. | 2003 | Gastroenterol. Clin. Biol. | pmid:12700506 |
| McCaig LF et al. | Antimicrobial drug prescription in ambulatory care settings, United States, 1992-2000. | 2003 | Emerging Infect. Dis. | pmid:12702222 |
| Di Mario F et al. | Use of lactoferrin for Helicobacter pylori eradication. Preliminary results. | J. Clin. Gastroenterol. | pmid:12702979 | |
| Journeau P et al. | Buruli's ulcer: three cases diagnosed and treated in France. | 2003 | J Pediatr Orthop B | pmid:12703041 |
| Cascio A and Colomba C | [Macrolides in the treatment of children with Mediterranean spotted fever]. | 2002 | Infez Med | pmid:12704264 |
| Melo-Cristino J et al. | Macrolide resistance in Streptococcus pneumoniae isolated from patients with community-acquired lower respiratory tract infections in Portugal: results of a 3-year (1999-2001) multicenter surveillance study. | 2003 | Microb. Drug Resist. | pmid:12705685 |
| Neto AS et al. | Risk factors for the nasopharyngeal carriage of respiratory pathogens by Portuguese children: phenotype and antimicrobial susceptibility of Haemophilus influenzae and Streptococcus pneumoniae. | 2003 | Microb. Drug Resist. | pmid:12705689 |
| Nishiyama Y et al. | Gastric inflammatory fibroid polyp treated with Helicobacter pylori eradication therapy. | 2003 | Intern. Med. | pmid:12705792 |
| Hardy RD et al. | Antimicrobial and immunologic activities of clarithromycin in a murine model of Mycoplasma pneumoniae-induced pneumonia. | 2003 | Antimicrob. Agents Chemother. | pmid:12709330 |
| Jacks SS et al. | In vitro susceptibilities of Rhodococcus equi and other common equine pathogens to azithromycin, clarithromycin, and 20 other antimicrobials. | 2003 | Antimicrob. Agents Chemother. | pmid:12709351 |
| Cakan H et al. | Assessment of antibiotic susceptibility of Ureaplasma urealyticum from prostitutes and outpatient clinic patients using the E-test and agar dilution method. | 2003 | Chemotherapy | pmid:12714809 |