| MeSH term | MeSH ID | Detail |
|---|---|---|
| Bacterial Infections | D001424 | 21 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Stomach Diseases | D013272 | 7 associated lipids |
| Lung Diseases | D008171 | 37 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Skin Neoplasms | D012878 | 12 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Leishmaniasis, Visceral | D007898 | 13 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Katayama Y et al. | Neuroprotective effects of clarithromycin against neuronal damage in cerebral ischemia and in cultured neuronal cells after oxygen-glucose deprivation. | 2017 | Life Sci. | pmid:27825902 |
| Moj D et al. | Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug-Drug Interactions and Co-medication Regimens. | 2017 | AAPS J | pmid:27822600 |
| Akpinar Z et al. | Improving the standard sequential treatment of Helicobacter pylori with either extended treatment or by adding bismuth. | 2017 | Arab J Gastroenterol | pmid:28532623 |
| Beckman E et al. | A Novel Stool PCR Test for Helicobacter pylori May Predict Clarithromycin Resistance and Eradication of Infection at a High Rate. | 2017 | J. Clin. Microbiol. | pmid:28515219 |
| Kajihara Y et al. | Analysis of the cost-effectiveness of using vonoprazan-amoxicillin-clarithromycin triple therapy for first-line Helicobacter pylori eradication. | 2017 | Scand. J. Gastroenterol. | pmid:27806639 |
| Yan J et al. | Survey about the use of clarithromycin in an ENT outpatient department of a tertiary hospital. | 2017 | Eur Arch Otorhinolaryngol | pmid:28508178 |
| Shaulov A et al. | Progressive refractory light chain amyloidosis and multiple myeloma patients are responsive to the addition of clarithromycin to IMiD based therapy. | 2017 | Am. J. Hematol. | pmid:27804150 |
| DaCosta A et al. | Outcomes associated with antibiotic regimens for treatment of Mycobacterium abscessus in cystic fibrosis patients. | 2017 | J. Cyst. Fibros. | pmid:28495380 |
| Sharifi R et al. | Dietary PUFA Increase Apoptosis in Stomach of Patients with Dyspeptic Symptoms and Infected with H. pylori. | 2017 | Lipids | pmid:28493185 |
| Reddy AB and Reddy ND | Development of Multiple-Unit Floating Drug Delivery System of Clarithromycin: Formulation, in vitro Dissolution by Modified Dissolution Apparatus, in vivo Radiographic Studies in Human Volunteers. | 2017 | Drug Res (Stuttg) | pmid:28449156 |
| Ivanová L et al. | Estimation of amount of selected pharmaceuticals sorbed onto digested sludge from wastewater treatment plant Bratislava-Petržalka. | 2017 | Environ. Res. | pmid:28183039 |
| Giguère S et al. | Antimicrobial Resistance in . | 2017 | Microbiol Spectr | pmid:29052538 |
| Giguère S | Treatment of Infections Caused by Rhodococcus equi. | 2017 | Vet. Clin. North Am. Equine Pract. | pmid:28161038 |
| Berni E et al. | Risk of cardiovascular events, arrhythmia and all-cause mortality associated with clarithromycin versus alternative antibiotics prescribed for respiratory tract infections: a retrospective cohort study. | 2017 | BMJ Open | pmid:28115334 |
| Yatera K et al. | The additive effect of clarithromycin on influenza A infection in the elderly patients and patients with comorbid diseases. | 2017 | Respir Investig | pmid:29153420 |
| Lee MC et al. | Antimicrobial resistance in Mycobacterium abscessus complex isolated from patients with skin and soft tissue infections at a tertiary teaching hospital in Taiwan. | 2017 | J. Antimicrob. Chemother. | pmid:29091186 |
| Takahashi C et al. | Morphological study of efficacy of clarithromycin-loaded nanocarriers for treatment of biofilm infection disease. | 2017 | Med Mol Morphol | pmid:27119723 |
| Laidler N | Cutaneous infection with paucibacillary treated successfully with a modified antituberculous drug regimen. | 2017 | BMJ Case Rep | pmid:29275384 |
| Lee JS et al. | Implication of species change of Nontuberculous Mycobacteria during or after treatment. | 2017 | BMC Pulm Med | pmid:29262802 |
| Ruiter R et al. | Helicobacter pylori resistance in the Netherlands: a growing problem? | 2017 | Neth J Med | pmid:29219812 |
| Mukherjee D et al. | Vancomycin and Clarithromycin Show Synergy against . | 2017 | Antimicrob. Agents Chemother. | pmid:28923867 |
| Tsay FW et al. | A Randomized Controlled Trial Shows that both 14-Day Hybrid and Bismuth Quadruple Therapies Cure Most Patients with Helicobacter pylori Infection in Populations with Moderate Antibiotic Resistance. | 2017 | Antimicrob. Agents Chemother. | pmid:28807915 |
| Oh ES et al. | Effects of clarithromycin on the pharmacokinetics of evogliptin in healthy volunteers. | 2017 | J Clin Pharm Ther | pmid:28806472 |
| Kuo YT et al. | Primary antibiotic resistance in Helicobacter pylori in the Asia-Pacific region: a systematic review and meta-analysis. | 2017 | Lancet Gastroenterol Hepatol | pmid:28781119 |
| Ramas M et al. | Efficacy and safety of rifaximin associated with standard triple therapy (omeprazole, clarithromycin and amoxicillin) for H. pylori eradication: A phase IV pilot clinical trial. | 2017 | Gastroenterol Hepatol | pmid:28780968 |
| Sue S et al. | The Superiority of Vonoprazan-based First-line Triple Therapy with Clarithromycin: A Prospective Multi-center Cohort Study on Helicobacter pylori Eradication. | 2017 | Intern. Med. | pmid:28566587 |
| Hu Y et al. | Novel and Effective Therapeutic Regimens for in an Era of Increasing Antibiotic Resistance. | 2017 | Front Cell Infect Microbiol | pmid:28529929 |
| Jeong SH et al. | Mycobacteriological characteristics and treatment outcomes in extrapulmonary Mycobacterium abscessus complex infections. | 2017 | Int. J. Infect. Dis. | pmid:28522316 |
| Kishida D et al. | Intractable Cutaneous Nontuberculous Mycobacteriosis (Mycobacterium abscessus) during Treatment for Systemic Lupus Erythematosus. | 2017 | Intern. Med. | pmid:28502947 |
| Jung YS et al. | Systematic review with meta-analysis: the efficacy of vonoprazan-based triple therapy on Helicobacter pylori eradication. | 2017 | Aliment. Pharmacol. Ther. | pmid:28497487 |
| Sharman MJ et al. | Gastrokine mRNA expression in gastric tissue from dogs with helicobacter colonisation but without inflammatory change during treatment. | 2017 | Vet. Immunol. Immunopathol. | pmid:28494926 |
| O'Brien CR et al. | Feline leprosy due to Candidatus 'Mycobacterium tarwinense':Further clinical and molecular characterisation of 15 previously reported cases and an additional 27 cases | 2017 | J. Feline Med. Surg. | pmid:28438086 |
| Kristin F et al. | Dissolution and dissolution/permeation experiments for predicting systemic exposure following oral administration of the BCS class II drug clarithromycin. | 2017 | Eur J Pharm Sci | pmid:28179133 |
| Chen D et al. | Phenotypic and Molecular Antimicrobial Susceptibility of Helicobacter pylori. | 2017 | Antimicrob. Agents Chemother. | pmid:28167563 |
| Olesen JS et al. | Mycobacterium chelonae hand infection after steroid injection in a patient with rheumatoid arthritis receiving long-term linezolid therapy. | 2017 | BMJ Case Rep | pmid:28137898 |
| Chang JY et al. | Triple therapy versus sequential therapy for the first-line Helicobacter pylori eradication. | 2017 | BMC Gastroenterol | pmid:28109257 |
| Huang CC et al. | In vitro activity of aminoglycosides, clofazimine, d-cycloserine and dapsone against 83 Mycobacterium avium complex clinical isolates. | 2018 | J Microbiol Immunol Infect | pmid:28705770 |
| Morgene MF et al. | HaCaT epithelial cells as an innovative novel model of rhinovirus infection and impact of clarithromycin treatment on infection kinetics. | 2018 | Virology | pmid:30077071 |
| Chen SA et al. | HLA-A*02:07 Allele Associates with Clarithromycin-Induced Cutaneous Adverse Drug Reactions in Chinese Patients. | 2018 | Basic Clin. Pharmacol. Toxicol. | pmid:29575644 |
| van Dyk M et al. | Assessment of inter-racial variability in CYP3A4 activity and inducibility among healthy adult males of Caucasian and South Asian ancestries. | 2018 | Eur. J. Clin. Pharmacol. | pmid:29572563 |
| Chen J et al. | Application of next-generation sequencing to characterize novel mutations in clarithromycin-susceptible Helicobacter pylori strains with A2143G of 23S rRNA gene. | 2018 | Ann. Clin. Microbiol. Antimicrob. | pmid:29562911 |
| RodrÃguez-Sevilla G et al. | Non-Tuberculous Mycobacteria multispecies biofilms in cystic fibrosis: development of an in vitro Mycobacterium abscessus and Pseudomonas aeruginosa dual species biofilm model. | 2018 | Int. J. Med. Microbiol. | pmid:29555180 |
| Compain F et al. | In vitro activity of tedizolid against the Mycobacterium abscessus complex. | 2018 | Diagn. Microbiol. Infect. Dis. | pmid:29217419 |
| Li H et al. | Inappropriate treatment in Helicobacter pylori eradication failure: a retrospective study. | 2018 | Scand. J. Gastroenterol. | pmid:29214879 |
| Jung JH et al. | Clinical Outcomes of Standard Triple Therapy Plus Probiotics or Concomitant Therapy for Infection. | 2018 | Gut Liver | pmid:29212313 |
| Deng J et al. | Lack of additional effects of long-term, low-dose clarithromycin combined treatment compared with topical steroids alone for chronic rhinosinusitis in China: a randomized, controlled trial. | 2018 | Int Forum Allergy Rhinol | pmid:29195025 |
| Beer-Davidson G et al. | Detection of Helicobacter pylori in stool samples of young children using real-time polymerase chain reaction. | 2018 | Helicobacter | pmid:29181860 |
| De Lorenzi G et al. | Mycobacterium genavense Infection in a Domestic Ferret (Mustela putorius furo). | 2018 | Top Companion Anim Med | pmid:30502861 |
| McNicholl AG et al. | Probiotic supplementation with Lactobacillus plantarum and Pediococcus acidilactici for Helicobacter pylori therapy: A randomized, double-blind, placebo-controlled trial. | 2018 | Helicobacter | pmid:30141228 |
| Choi IJ et al. | Helicobacter pylori Therapy for the Prevention of Metachronous Gastric Cancer. | 2018 | N. Engl. J. Med. | pmid:29562147 |