clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Stomach Diseases D013272 7 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Skin Neoplasms D012878 12 associated lipids
Colitis D003092 69 associated lipids
Leishmaniasis, Visceral D007898 13 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Khurana R et al. An update on anti-Helicobacter pylori treatment in children. 2005 Can. J. Gastroenterol. pmid:16010308
Chiba N et al. Ranitidine bismuth citrate. 2001 Can. J. Gastroenterol. pmid:11429668
Chiba N and Marshall CP Omeprazole once or twice daily with clarithromycin and metronidazole for Helicobacter pylori. 2000 Can. J. Gastroenterol. pmid:10655024
Hunt RH et al. Implications of antibiotic resistance in the management of Helicobacter pylori infection: Canadian Helicobacter Study Group. 2000 Can. J. Gastroenterol. pmid:11111109
Smaill F Antibiotic susceptibility and resistance testing: an overview. 2000 Can. J. Gastroenterol. pmid:11111110
Fallone CA Epidemiology of the antibiotic resistance of Helicobacter pylori in Canada. 2000 Can. J. Gastroenterol. pmid:11111111
Chiba N Effects of in vitro antibiotic resistance on treatment: bismuth-containing regimens. 2000 Can. J. Gastroenterol. pmid:11111112
Yoh M et al. Effect of subinhibitory concentrations of antimicrobial agents (quinolones and macrolide) on the production of verotoxin by enterohemorrhagic Escherichia coli O157:H7. 1999 Can. J. Microbiol. pmid:10526400
Altman E et al. Lipopolysaccharide glycotyping of clarithromycin-resistant and clarithromycin-susceptible Canadian isolates of Helicobacter pylori. 2014 Can. J. Microbiol. pmid:24392924
Slany M et al. Mycobacterium marinum infections in humans and tracing of its possible environmental sources. 2012 Can. J. Microbiol. pmid:22182182
Can F et al. Diagnosis of Helicobacter pylori infection and determination of clarithromycin resistance by fluorescence in situ hybridization from formalin-fixed, paraffin-embedded gastric biopsy specimens. 2005 Can. J. Microbiol. pmid:16175205
Lee SB et al. Fourth-generation fluoroquinolones in the treatment of mycobacterial infectious keratitis after laser-assisted in situ keratomileusis surgery. 2005 Can. J. Ophthalmol. pmid:16391641
Chan EY and Dell SD Pediatric interstitial lung disease masquerading as difficult asthma: management dilemmas for rare lung disease in children. 2005 Can. Respir. J. pmid:16247529
Glezos JD et al. Pneumonitis after inhalation of mercury vapours. 2006 Can. Respir. J. pmid:16642230
Sandrini A et al. Diffuse panbronchiolitis in a Caucasian man in Canada. 2003 Nov-Dec Can. Respir. J. pmid:14679410
Weiss K et al. Clinical characteristics at initial presentation and impact of dual therapy on the outcome of bacteremic Streptococcus pneumoniae pneumonia in adults. 2004 Nov-Dec Can. Respir. J. pmid:15611810
Marrie TJ et al. Symptom resolution in patients with Mycoplasma pneumoniae pneumonia. 2004 Nov-Dec Can. Respir. J. pmid:15611807
Torresin A et al. Vinca alkaloids and macrolides in human immunodeficiency virus-related malignancies: a safe association. 1996 Cancer Chemother. Pharmacol. pmid:8995518
Grosso F et al. A comprehensive safety analysis confirms rhabdomyolysis as an uncommon adverse reaction in patients treated with trabectedin. 2012 Cancer Chemother. Pharmacol. pmid:22484722
Makihara K et al. Clarithromycin co-administration does not increase irinotecan (CPT-11) toxicity in colorectal cancer patients. 2017 Cancer Chemother. Pharmacol. pmid:28711984
Chen Y et al. In vitro assessment of cytochrome P450 inhibition and induction potential of azacitidine. 2010 Cancer Chemother. Pharmacol. pmid:20119716
Kane CL et al. Disseminated cutaneous Mycobacterium chelonae infection. 2000 Mar-Apr Cancer Control pmid:10783823
Sarihan S et al. Evaluation of infections in non-small cell lung cancer patients treated with radiotherapy. 2005 Cancer Detect. Prev. pmid:15829379
Uemura N et al. Effect of Helicobacter pylori eradication on subsequent development of cancer after endoscopic resection of early gastric cancer. 1997 Cancer Epidemiol. Biomarkers Prev. pmid:9264278
Noonan KA et al. Targeting immune suppression with PDE5 inhibition in end-stage multiple myeloma. 2014 Cancer Immunol Res pmid:24878583
Yatsunami J et al. Roxithromycin and clarithromycin, 14-membered ring macrolides, potentiate the antitumor activity of cytotoxic agents against mouse B16 melanoma cells. 1999 Cancer Lett. pmid:10660084
Zhang S et al. Early or late antibiotic intervention prevents Helicobacter pylori-induced gastric cancer in a mouse model. 2015 Cancer Lett. pmid:25853150
Oakman C et al. Role of lapatinib in the first-line treatment of patients with metastatic breast cancer. 2010 Cancer Manag Res pmid:21188093
Lee CW et al. Helicobacter pylori eradication prevents progression of gastric cancer in hypergastrinemic INS-GAS mice. 2008 Cancer Res. pmid:18441088
Cao X et al. Eradication of Helicobacter pylori induces apoptosis and inhibits proliferation of heterotopic proliferative glands in infected Mongolian gerbils. 2004 Cancer Sci. pmid:15546504
Pan-In P et al. Ethyl cellulose nanoparticles: clarithomycin encapsulation and eradication of H. pylori. 2014 Carbohydr Polym pmid:24815396
Zhang Y et al. Helicobacter pylori, cyclooxygenase-2 and evolution of gastric lesions: results from an intervention trial in China. 2015 Carcinogenesis pmid:26449252
Thun MJ et al. The global burden of cancer: priorities for prevention. 2010 Carcinogenesis pmid:19934210
Dingemanse C et al. Akkermansia muciniphila and Helicobacter typhlonius modulate intestinal tumor development in mice. 2015 Carcinogenesis pmid:26320104
Escalante CP and Zalpour A Vascular endothelial growth factor inhibitor-induced hypertension: basics for primary care providers. 2011 Cardiol Res Pract pmid:21629798
Winkel P et al. Excess sudden cardiac deaths after short-term clarithromycin administration in the CLARICOR trial: why is this so, and why are statins protective? 2011 Cardiology pmid:21447948
Gluud C et al. Clarithromycin for 2 weeks for stable coronary heart disease: 6-year follow-up of the CLARICOR randomized trial and updated meta-analysis of antibiotics for coronary heart disease. 2008 Cardiology pmid:18451646
Paz A and Potasman I Mycoplasma-associated carditis. Case reports and review. 2002 Cardiology pmid:11978954
Andersen SS et al. Clarithromycin use and risk of death in patients with ischemic heart disease. 2010 Cardiology pmid:20523043
Page RL et al. An alternative salvage regimen for Helicobacter pylori-resistant patients with heart failure. 2008 Cardiology pmid:17971660
Wang YH et al. Effects of multiple doses of clarithromycin on the pharmacokinetics of laropiprant in healthy subjects. 2011 Cardiovasc Ther pmid:20337634
Suzuki M et al. A case of yellow nail syndrome with dramatically improved nail discoloration by oral clarithromycin. 2011 Case Rep Dermatol pmid:22220146
Salik D and Del Marmol V Refractory Hand Ulceration: A Case of Chronic Ulceration and Sporotrichoid Spread in a Fish Tank Hobbyist following Mycobacterium marinum Infection. 2011 Case Rep Dermatol pmid:21792350
Wongkitisophon P et al. Cutaneous Mycobacterium abscessus Infection Associated with Mesotherapy Injection. 2011 Case Rep Dermatol pmid:21487459
Kamijo F et al. A Case of Mycobacterial Skin Disease Caused by Mycobacterium peregrinum, and a Review of Cutaneous Infection. 2012 Case Rep Dermatol pmid:22548041
Pasha SF et al. Hemosuccus Pancreaticus in the Era of Capsule Endoscopy and Double Balloon Enteroscopy Complicated by Multifocal Mycobacterium chelonae/abscessus Infection. 2007 Case Rep Gastroenterol pmid:21487470
Abe Y et al. Esophageal Adenocarcinoma Developing after Eradication of Helicobacter pylori. 2011 Case Rep Gastroenterol pmid:21769287
Asano N et al. Signet Ring Cell Gastric Cancer Occurring after Radiation Therapy for Helicobacter pylori-Uninfected Mucosa-Associated Lymphoid Tissue Lymphoma. 2011 Case Rep Gastroenterol pmid:21712948
Shah M et al. Transient Psychotic Episode Induced by Helicobacter pylori Triple Therapy Treatment. 2012 Case Rep Gastroenterol pmid:22855656
Hasosah M et al. Mucosa-associated lymphoid tissue lymphoma of the lacrimal gland: sustained remission after eradication of helicobacter pylori infection. 2011 Case Rep Gastrointest Med pmid:22606434
Shimabukuro-Vornhagen A et al. Acquired Long QT Syndrome and Torsade de Pointes Associated with HIV Infection. 2010 Case Rep Med pmid:20827440
Namendys-Silva SA et al. Acute respiratory distress syndrome caused by influenza B virus infection in a patient with diffuse large B-cell lymphoma. 2011 Case Rep Med pmid:22110513
Bamias G et al. Atypical mycobacterial infection presenting as persistent skin lesion in a patient with ulcerative colitis. 2011 Case Rep Med pmid:22007233
Folaranmi SE et al. Suspected intestinal tuberculosis might be Crohn's disease. 2010 Case Rep Med pmid:20490287
Kurugol Z et al. Severe Hemolytic Anemia Associated with Mild Pneumonia Caused by Mycoplasma pneumonia. 2012 Case Rep Med pmid:23049568
Cetin M et al. Clarithromycin-Induced Long QT Syndrome: A Case Report. 2012 Case Rep Med pmid:22489247
Eruz ED et al. A case of brucellosis presenting with multiple hypodense splenic lesions and bilateral pleural effusions. 2011 Case Rep Med pmid:21687542
Zenone T Systemic Bartonella henselae Infection in Immunocompetent Adult Presenting as Fever of Unknown Origin. 2011 Case Rep Med pmid:21629850
Papacharalampous GX et al. Bilateral Peritonsillar Abscesses: A Case Presentation and Review of the Current Literature with regard to the Controversies in Diagnosis and Treatment. 2011 Case Rep Med pmid:21629820
Ablanedo-Terrazas Y et al. Palatal Actinomycosis and Kaposi Sarcoma in an HIV-Infected Subject with Disseminated Mycobacterium avium-intracellulare Infection. 2012 Case Rep Med pmid:22481952
Samet JD et al. Cronkhite-Canada Syndrome: Gastric Involvement Diagnosed by MDCT. 2009 Case Rep Med pmid:19721708
Melo N et al. Bordetella pertussis, an agent not to forget: a case report. 2009 Cases J pmid:19200362
Navaravong L et al. Cigarettes-induced acute eosinophilic pneumonia: a case report. 2008 Cases J pmid:19102783
Del Castillo Y et al. Interstitial lung disease associated to erlotinib treatment: a case report. 2010 Cases J pmid:20509858
Riordan AI et al. Successful treatment with azithromycin and rifampicin of penicillin and cephalosporin insensitive pneumococcal osteomyelitis in a child with HIV infection: a case report. 2008 Cases J pmid:18959805
Christianakis E et al. Pelvic plastron secondary to acute appendicitis in a child presented as appendiceal intussusception. A case report. 2008 Cases J pmid:18761733
Adejumo A et al. Fatal dual infection with Salmonella and Mycobacterium avium complex infection in a patient with advanced acquired immunodeficiency syndrome: a case report. 2009 Cases J pmid:20181177
Ersoz F et al. MALT lymphoma of the rectum, presenting with rectal prolapsus: a case report. 2010 Cases J pmid:20180989
Popalzai MJ et al. Chronic fungal sinusitis leading to disastrous cerebral aspergillosis: a case report. 2009 Cases J pmid:20069073
Kassha K et al. Severe Legionnaires disease complicated by multi-organ dysfunction in a previously healthy patient: a case report. 2009 Cases J pmid:20062668
Wiedmann M et al. Sudden elevation of liver enzymes in a 64-year-old patient: a case report. 2009 Cases J pmid:19946449
Shaikh S et al. Incomplete, atypical kawasaki disease or evolving systemic juvenile idiopathic arthritis: a case report. 2009 Cases J pmid:19918500
Frye SA and Decou JM Pediatric bronchogenic cyst complicated by atypical mycobacterium infection: a case report. 2009 Cases J pmid:19918449
Abbott GW et al. MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia. 1999 Cell pmid:10219239
Suzuki M et al. Diversity of Cl(-) channels. 2006 Cell. Mol. Life Sci. pmid:16314923
Jakubů V et al. Trends in the Minimum Inhibitory Concentrations of Erythromycin, Clarithromycin, Azithromycin, Ciprofloxacin, and Trimethoprim/Sulfamethoxazole for Strains of Bordetella pertussis isolated in the Czech Republic in 1967-2015. 2017 Cent. Eur. J. Public Health pmid:29346850
de Silva HA et al. Comparison of one week and two weeks of triple therapy for the eradication of Helicobacter pylori in a Sri Lankan population: a randomised, controlled study. 2004 Ceylon Med J pmid:15693450
Lin TY et al. An open-label, randomized comparison of levofloxacin and amoxicillin/clavulanate plus clarithromycin for the treatment of hospitalized patients with community-acquired pneumonia. Chang Gung Med J pmid:17939262
El-Enany NM et al. Spectrofluorimetric determination of sertraline in dosage forms and human plasma through derivatization with 9-fluorenylmethyl chloroformate. 2011 Chem Cent J pmid:21978386
Sadeghi-Khomami A et al. Glycosidase inhibition by macrolide antibiotics elucidated by STD-NMR spectroscopy. 2008 Chem. Biol. pmid:18635010
Nishimoto A et al. Studies on macrolide antibiotics I. Synthesis and antibacterial activity of erythromycin A 9-O-substituted oxime ether derivatives against Mycobacterium avium complex. 2001 Chem. Pharm. Bull. pmid:11558597
Ishizaka T et al. Bitterness evaluation of medicines for pediatric use by a taste sensor. 2004 Chem. Pharm. Bull. pmid:15304986
Rajinikanth PS et al. Formulation and evaluation of clarithromycin microspheres for eradication of Helicobacter pylori. 2008 Chem. Pharm. Bull. pmid:19043235
Tanigake A et al. The bitterness intensity of clarithromycin evaluated by a taste sensor. 2003 Chem. Pharm. Bull. pmid:14600366
Zhang X et al. Effect of pore former on the properties of casted film prepared from blends of Eudragit NE 30 D and Eudragit L 30 D-55. 2007 Chem. Pharm. Bull. pmid:17666856
Fujiki S et al. Stabilization mechanism of clarithromycin tablets under gastric pH conditions. 2011 Chem. Pharm. Bull. pmid:21532191
Yajima T et al. Method of evaluation of the bitterness of clarithromycin dry syrup. 2002 Chem. Pharm. Bull. pmid:11848199
Tozuka Y et al. Characterization and quantitation of clarithromycin polymorphs by powder X-ray diffractometry and solid-state NMR spectroscopy. 2002 Chem. Pharm. Bull. pmid:12192153
Tsuji E et al. Evaluation of bitterness suppression of macrolide dry syrups by jellies. 2006 Chem. Pharm. Bull. pmid:16508183
Rajinikanth PS and Mishra B Stomach-site specific drug delivery system of clarithromycin for eradication of Helicobacter pylori. 2009 Chem. Pharm. Bull. pmid:19801860
Ishii K et al. In vitro dissolution tests corresponding to the in vivo dissolution of clarithromycin tablets in the stomach and intestine. 1995 Chem. Pharm. Bull. pmid:8575034
Yajima T et al. Optimum heat treatment conditions for masking the bitterness of the clarithromycin wax matrix. 2003 Chem. Pharm. Bull. pmid:14600362
Ishizaka T et al. The suppression of enhanced bitterness intensity of macrolide dry syrup mixed with an acidic powder. 2007 Chem. Pharm. Bull. pmid:17917288
Ishizaka T et al. Quality of twelve clarithromycin dry syrup formulations-bitterness, grittiness and uniformity of drug loading. 2008 Chem. Pharm. Bull. pmid:18827376
Gattani SG et al. Floating-mucoadhesive beads of clarithromycin for the treatment of Helicobacter pylori infection. 2010 Chem. Pharm. Bull. pmid:20522987
Koide T et al. Analysis of Distribution of Ingredients in Commercially Available Clarithromycin Tablets Using Near-Infrared Chemical Imaging with Principal Component Analysis and Partial Least Squares. 2015 Chem. Pharm. Bull. pmid:26329859
Yajima T et al. Optimum spray congealing conditions for masking the bitter taste of clarithromycin in wax matrix. 1999 Chem. Pharm. Bull. pmid:10071855
Li H et al. Prediction of genotoxicity of chemical compounds by statistical learning methods. 2005 Chem. Res. Toxicol. pmid:15962942
Hur J et al. Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. 2015 Chem. Res. Toxicol. pmid:25811541
Loganathan B et al. Contamination profiles and mass loadings of macrolide antibiotics and illicit drugs from a small urban wastewater treatment plant. 2009 Chemosphere pmid:19121838