| MeSH term | MeSH ID | Detail |
|---|---|---|
| Bacterial Infections | D001424 | 21 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Stomach Diseases | D013272 | 7 associated lipids |
| Lung Diseases | D008171 | 37 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Skin Neoplasms | D012878 | 12 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Leishmaniasis, Visceral | D007898 | 13 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Stolte M et al. | Cure of autoimmune gastritis by Helicobacter pylori eradication in a 21-year-old male. | 1998 | Z Gastroenterol | pmid:9773482 |
| Adamek RJ and Bethke TD | Cure of Helicobacter pylori infection and healing of duodenal ulcer: comparison of pantoprazole-based one-week modified triple therapy versus two-week dual therapy. The International Pantoprazole HP Study Group. | 1998 | Am. J. Gastroenterol. | pmid:9772056 |
| Stack WA et al. | Safety and efficacy of rabeprazole in combination with four antibiotic regimens for the eradication of Helicobacter pylori in patients with chronic gastritis with or without peptic ulceration. | 1998 | Am. J. Gastroenterol. | pmid:9772054 |
| Mukunda BN et al. | Clarithromycin therapy for bacillary peliosis did not prevent bacillary angiomatosis. | 1998 | Clin. Infect. Dis. | pmid:9770180 |
| Laine L et al. | Low rate of emergence of clarithromycin-resistant Helicobacter pylori with amoxycillin co-therapy. | 1998 | Aliment. Pharmacol. Ther. | pmid:9768532 |
| Louw JA et al. | Helicobacter pylori eradication and ulcer healing with daily lansoprazole, plus 1 or 2 weeks co-therapy with amoxycillin and clarithromycin. | 1998 | Aliment. Pharmacol. Ther. | pmid:9768531 |
| Pipkin GA et al. | Review article: one-week clarithromycin triple therapy regimens for eradication of Helicobacter pylori. | 1998 | Aliment. Pharmacol. Ther. | pmid:9768524 |
| Horgen L et al. | Postantibiotic effect of amikacin, rifampin, sparfloxacin, clofazimine and clarithromycin against Mycobacterium avium. | 1997 | Res. Microbiol. | pmid:9765852 |
| Heald AE et al. | Taste and smell complaints in HIV-infected patients. | 1998 | AIDS | pmid:9764787 |
| Mégraud F and Doermann HP | Clinical relevance of resistant strains of Helicobacter pylori: a review of current data. | 1998 | Gut | pmid:9764043 |
| Hawkey CJ et al. | Randomised controlled trial of Helicobacter pylori eradication in patients on non-steroidal anti-inflammatory drugs: HELP NSAIDs study. Helicobacter Eradication for Lesion Prevention. | 1998 | Lancet | pmid:9759744 |
| Pontani D et al. | Susceptibility of European respiratory tract isolates to trovafloxacin, ciprofloxacin, clarithromycin, azithromycin and ampicillin. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9758284 |
| Kubas G and Gospodarek T | [The use of clarithromycin and amoxycillin in pediatric acute otitis media]. | 1997 | Otolaryngol Pol | pmid:9757683 |
| Denys A | [Theoretical basis for the antibiotic therapy of the upper part of the respiratory system]. | 1997 | Otolaryngol Pol | pmid:9757681 |
| Greenblatt DJ et al. | Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences. | 1998 | Clin. Pharmacol. Ther. | pmid:9757151 |
| Debets-Ossenkopp YJ et al. | Explaining the bias in the 23S rRNA gene mutations associated with clarithromycin resistance in clinical isolates of Helicobacter pylori. | 1998 | Antimicrob. Agents Chemother. | pmid:9756790 |
| Gikas A et al. | In vitro susceptibility of Coxiella burnetii to trovafloxacin in comparison with susceptibilities to pefloxacin, ciprofloxacin, ofloxacin, doxycycline, and clarithromycin. | 1998 | Antimicrob. Agents Chemother. | pmid:9756789 |
| Apseloff G et al. | Comparison of azithromycin and clarithromycin in their interactions with rifabutin in healthy volunteers. | 1998 | J Clin Pharmacol | pmid:9753212 |
| Huang WH et al. | New one-week, low-dose triple therapy for the treatment of duodenal ulcer with Helicobacter pylori infection. | 1998 | Zhonghua Yi Xue Za Zhi (Taipei) | pmid:9745160 |
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| Sevin E et al. | Co-detection of Helicobacter pylori and of its resistance to clarithromycin by PCR. | 1998 | FEMS Microbiol. Lett. | pmid:9742711 |
| Siu LK et al. | Evaluation of a selective transport medium for gastric biopsy specimens to be cultured for Helicobacter pylori. | 1998 | J. Clin. Microbiol. | pmid:9738066 |
| Alder JD et al. | Dynamics of clarithromycin and azithromycin efficacies against experimental Haemophilus influenzae pulmonary infection. | 1998 | Antimicrob. Agents Chemother. | pmid:9736568 |
| Lamouliatte H et al. | Dual therapy using a double dose of lansoprazole with amoxicillin versus triple therapy using a double dose of lansoprazole, amoxicillin, and clarithromycin to eradicate Helicobacter pylori infection: results of a prospective randomized open study. | 1998 | Am. J. Gastroenterol. | pmid:9732938 |
| Chu KM et al. | A prospective randomized trial comparing the use of omeprazole-based dual and triple therapy for eradication of Helicobacter pylori. | 1998 | Am. J. Gastroenterol. | pmid:9732921 |
| Vakil N et al. | Clarithromycin-resistant Helicobacter pylori in patients with duodenal ulcer in the United States. | 1998 | Am. J. Gastroenterol. | pmid:9732920 |
| Lanza FL et al. | Ranitidine bismuth citrate plus clarithromycin: a dual therapy regimen for patients with duodenal ulcer. | 1998 | Helicobacter | pmid:9731994 |
| Bazzoli F et al. | Efficacy of lansoprazole in eradicating Helicobacter pylori: a meta-analysis. | 1998 | Helicobacter | pmid:9731991 |
| Graham DY et al. | Effect of H. pylori infection and CagA status on leukocyte counts and liver function tests: extra-gastric manifestations of H. pylori infection. | 1998 | Helicobacter | pmid:9731987 |
| Barzilai A et al. | Successful treatment of disseminated Mycobacterium simiae infection in AIDS patients. | 1998 | Scand. J. Infect. Dis. | pmid:9730300 |
| Gorski JC et al. | The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin. | 1998 | Clin. Pharmacol. Ther. | pmid:9728893 |
| Bermudez LE et al. | Clarithromycin significantly improves interleukin-12-mediated anti-Mycobacterium avium activity and abolishes toxicity in mice. | 1998 | J. Infect. Dis. | pmid:9728568 |
| Bayoumi AM and Redelmeier DA | Preventing Mycobacterium avium complex in patients who are using protease inhibitors: a cost-effectiveness analysis. | 1998 | AIDS | pmid:9727572 |
| Harris AW et al. | Incidence of duodenal ulcer healing after 1 week of proton pump inhibitor triple therapy for eradication of Helicobacter pylori. The Lansoprazole Helicobacter Study Group. | 1998 | Aliment. Pharmacol. Ther. | pmid:9726387 |
| Pazzi P et al. | Short-term low-dose pantoprazole-based triple therapy for cure of Helicobacter pylori infection in duodenal ulcer patients. | 1998 | Aliment. Pharmacol. Ther. | pmid:9726385 |
| Sung JJ et al. | One-week use of ranitidine bismuth citrate, amoxycillin and clarithromycin for the treatment of Helicobacter pylori-related duodenal ulcer. | 1998 | Aliment. Pharmacol. Ther. | pmid:9726384 |
| Nelson KG et al. | Results of operation in Mycobacterium avium-intracellulare lung disease. | 1998 | Ann. Thorac. Surg. | pmid:9725364 |
| Venuta A et al. | Azithromycin compared with clarithromycin for the treatment of streptococcal pharyngitis in children. | 1998 Jun-Jul | J. Int. Med. Res. | pmid:9718470 |
| Tanahashi T et al. | Analysis of the 13C-urea breath test for detection of Helicobacter pylori infection based on the kinetics of delta-13CO2 using laser spectroscopy. | 1998 | J. Gastroenterol. Hepatol. | pmid:9715426 |
| Cecchi R and Torelli E | Schönlein-Henoch purpura in association with duodenal ulcer and gastric Helicobacter pylori infection. | 1998 | J. Dermatol. | pmid:9714985 |
| Améndola R et al. | [Is dental plaque a normal Helicobacter pylori reservoir?]. | 1998 | Acta Gastroenterol. Latinoam. | pmid:9713656 |
| Bergmann JS and Woods GL | In vitro activity of antimicrobial combinations against clinical isolates of susceptible and resistant Mycobacterium tuberculosis. | 1998 | Int. J. Tuberc. Lung Dis. | pmid:9712275 |
| Fernández Bermejo M and GarcÃa Grávalos R | [Ebrotidine in the eradicating treatment of H. pylori]. | 1998 Jun-Jul | Gastroenterol Hepatol | pmid:9711019 |
| Burman WJ et al. | Long-term outcomes of treatment of Mycobacterium avium complex bacteremia using a clarithromycin-containing regimen. | 1998 | AIDS | pmid:9708410 |
| van der Wouden EJ et al. | One-week triple therapy with ranitidine bismuth citrate, clarithromycin and metronidazole versus two-week dual therapy with ranitidine bismuth citrate and clarithromycin for Helicobacter pylori infection: a randomized, clinical trial. | 1998 | Am. J. Gastroenterol. | pmid:9707042 |
| Wang G et al. | Genotypic characterization of clarithromycin-resistant and -susceptible Helicobacter pylori strains from the same patient demonstrates existence of two unrelated isolates. | 1998 | J. Clin. Microbiol. | pmid:9705423 |
| Ellenrieder V et al. | Influence of clarithromycin dosage on pantoprazole combined triple therapy for eradication of Helicobacter pylori. | 1998 | Aliment. Pharmacol. Ther. | pmid:9701524 |
| Takizawa H et al. | Erythromycin and clarithromycin attenuate cytokine-induced endothelin-1 expression in human bronchial epithelial cells. | 1998 | Eur. Respir. J. | pmid:9701415 |
| Fennerty MB et al. | A comparison of 10 and 14 days of lansoprazole triple therapy for eradication of Helicobacter pylori. | 1998 Aug 10-24 | Arch. Intern. Med. | pmid:9701099 |
| Hsieh PF et al. | Molecular mechanisms of clarithromycin resistance in Helicobacter pylori. | 1998 | J. Formos. Med. Assoc. | pmid:9700240 |
| Wakasugi H et al. | Effect of clarithromycin on renal excretion of digoxin: interaction with P-glycoprotein. | 1998 | Clin. Pharmacol. Ther. | pmid:9695727 |
| Hashimoto Y | [Eradication therapies for Helicobacter pylori]. | 1998 | Kansenshogaku Zasshi | pmid:9695480 |
| Habu Y et al. | Triple therapy with omeprazole, amoxicillin and clarithromycin is effective against Helicobacter pylori infection in gastric ulcer patients as well as in duodenal ulcer patients. Results of a randomized controlled trial in Japan. | 1998 Jul-Aug | Digestion | pmid:9693202 |
| Dobrilla G et al. | Ranitidine bismuth citrate with either clarithromycin 1 g/day or 1.5 g/day is equally effective in the eradication of H. pylori and healing of duodenal ulcer. | 1998 | Aliment. Pharmacol. Ther. | pmid:9692703 |
| Catalano F et al. | Ranitidine bismuth citrate versus omeprazole triple therapy for the eradication of Helicobacter pylori and healing of duodenal ulcer. | 1998 | Aliment. Pharmacol. Ther. | pmid:9692702 |
| Bardhan KD et al. | Pantoprazole-based 10-day triple therapy is effective in Helicobacter pylori eradication. | 1998 | Aliment. Pharmacol. Ther. | pmid:9692693 |
| Soepandi P et al. | The pattern of micro-organisms and the efficacy of new macrolide in acute lower respiratory tract infections. | 1998 | Respirology | pmid:9692520 |
| Bigard MA et al. | One-week triple therapy using omeprazole, amoxycillin and clarithromycin for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia: influence of dosage of omeprazole and clarithromycin. | 1998 | Aliment. Pharmacol. Ther. | pmid:9690730 |
| Portaels F et al. | In vitro susceptibility of Mycobacterium ulcerans to clarithromycin. | 1998 | Antimicrob. Agents Chemother. | pmid:9687409 |
| Martin SJ and Pendland SL | Bactericidal activity and postantibiotic effect of clarithromycin and 14-hydroxyclarithromycin, alone and in combination, against Legionella pneumophila. | 1998 | J. Antimicrob. Chemother. | pmid:9687103 |
| Bordet AL et al. | [Mycobacterium chelonae cutaneous infection: efficacy of prolonged treatment by clarithromycin]. | 1997 | Ann Dermatol Venereol | pmid:9686059 |
| Tonai A et al. | [Clarithromycin suppression of DNA synthesis by rat nasal mucosal cells enhanced by endotoxin instillation]. | 1997 | Jpn J Antibiot | pmid:9678983 |
| Grübel P and Cave DR | Factors affecting solubility and penetration of clarithromycin through gastric mucus. | 1998 | Aliment. Pharmacol. Ther. | pmid:9678818 |
| Ahuja V et al. | Lansoprazole and secnidazole with clarithromycin, amoxycillin or pefloxacin in the eradication of Helicobacter pylori in a developing country. | 1998 | Aliment. Pharmacol. Ther. | pmid:9678815 |
| Louw JA et al. | Two-week course of pantoprazole combined with 1 week of amoxycillin and clarithromycin is effective in Helicobacter pylori eradication and duodenal ulcer healing. | 1998 | Aliment. Pharmacol. Ther. | pmid:9678814 |
| Cammarota G et al. | One-week therapy for Helicobacter pylori eradication: ranitidine bismuth citrate plus medium-dose clarithromycin and either tinidazole or amoxycillin. | 1998 | Aliment. Pharmacol. Ther. | pmid:9678813 |
| Ricciardiello L et al. | Efficacy and safety of three 7-day Helicobacter pylori eradication regimens containing ranitidine bismuth citrate. | 1998 | Aliment. Pharmacol. Ther. | pmid:9678812 |
| Talley NJ et al. | Nizatidine in combination with amoxycillin and clarithromycin in the treatment of Helicobacter pylori infection. | 1998 | Aliment. Pharmacol. Ther. | pmid:9678811 |
| Perri F et al. | Relationship between the results of pre-treatment urea breath test and efficacy of eradication of Helicobacter pylori infection. | 1998 | Ital J Gastroenterol Hepatol | pmid:9675647 |
| Dunne EF et al. | Streptomyces pneumonia in a patient with human immunodeficiency virus infection: case report and review of the literature on invasive streptomyces infections. | 1998 | Clin. Infect. Dis. | pmid:9675460 |
| Dore MP et al. | Demonstration of unexpected antibiotic resistance of genotypically identical Helicobacter pylori isolates. | 1998 | Clin. Infect. Dis. | pmid:9675458 |
| de Boer WA et al. | Optimal treatment of Helicobacter pylori with ranitidine bismuth citrate (RBC): a randomized comparison between two 7-day triple therapies and a 14-day dual therapy. | 1998 | Am. J. Gastroenterol. | pmid:9672338 |
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| Kolkman JJ et al. | Ranitidine bismuth citrate with clarithromycin versus omeprazole with amoxycillin in the cure of Helicobacter pylori infection. | 1997 | Aliment. Pharmacol. Ther. | pmid:9663840 |
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| Pozzato P et al. | Ranitidine bismuth citrate plus clarithromycin 7-day regimen is effective in eradicating Helicobacter pylori in patients with duodenal ulcer. | 1998 | Aliment. Pharmacol. Ther. | pmid:9663724 |
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| Spinzi GC et al. | Comparison of omeprazole and lansoprazole in short-term triple therapy for Helicobacter pylori infection. | 1998 | Aliment. Pharmacol. Ther. | pmid:9663722 |
| Amsden GW et al. | Oral cimetidine prolongs clarithromycin absorption. | 1998 | Antimicrob. Agents Chemother. | pmid:9660986 |
| Klein JO | Clarithromycin and azithromycin. | 1998 | Pediatr. Infect. Dis. J. | pmid:9655546 |
| Wiedermann BL | Macrolides: clarithromycin and azithromycin. | 1998 | Pediatr Rev | pmid:9654947 |
| Moshkowitz M et al. | One-week triple therapy with omeprazole, clarithromycin, and nitroimidazole for Helicobacter pylori infection in children and adolescents. | 1998 | Pediatrics | pmid:9651466 |
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| Wharton JR et al. | Erythrasma treated with single-dose clarithromycin. | 1998 | Arch Dermatol | pmid:9645634 |
| Makhani S et al. | Atypical cervico-facial mycobacterial infections in childhood. | 1998 | Br J Oral Maxillofac Surg | pmid:9643597 |
| Grove DI et al. | Comparison of culture, histopathology and urease testing for the diagnosis of Helicobacter pylori gastritis and susceptibility to amoxycillin, clarithromycin, metronidazole and tetracycline. | 1998 | Pathology | pmid:9643503 |
| Gray VS | Syncopal episodes associated with cisapride and concurrent drugs. | 1998 | Ann Pharmacother | pmid:9640482 |
| Nordt SP et al. | Clarithromycin induced digoxin toxicity. | 1998 | J Accid Emerg Med | pmid:9639187 |
| Burman WJ et al. | AIDS-related Mycobacterium kansasii infection with initial resistance to clarithromycin. | 1998 | Diagn. Microbiol. Infect. Dis. | pmid:9635911 |
| Calvet Calvo X | [Treatment of Helicobacter pylori infections]. | 1998 | Gastroenterol Hepatol | pmid:9633184 |
| Miwa H et al. | Effectiveness of omeprazole-amoxicillin-clarithromycin (OAC) therapy for Helicobacter pylori infection in a Japanese population. | 1998 | Helicobacter | pmid:9631313 |
| Battaglia G et al. | Optimal PPI-based triple therapy for the cure of Helicobacter pylori infection: a single center comparison of four 14-day schedules. | 1998 | Helicobacter | pmid:9631310 |
| Fireman Z et al. | Helicobacter pylori and peptic ulcer disease therapies: a survey of gastroenterologists in Israel. | 1998 | Helicobacter | pmid:9631306 |
| Domingo D et al. | High frequency of mutations at position 2144 of the 23S rRNA gene in clarithromycin-resistant Helicobacter pylori strains isolated in Spain. | 1998 | J. Antimicrob. Chemother. | pmid:9630414 |