clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

Cross Reference

Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Stomach Diseases D013272 7 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Skin Neoplasms D012878 12 associated lipids
Colitis D003092 69 associated lipids
Leishmaniasis, Visceral D007898 13 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Per page 10 20 50 100 | Total 242

PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

Download all related citations
Per page 10 20 50 100 | Total 7636
Authors Title Published Journal PubMed Link
Lee SH et al. Sequential bilateral lung resection in a patient with Mycobacterium abscessus lung disease refractory to medical treatment. 2010 Yonsei Med. J. pmid:20046529
Jun HJ et al. Successful treatment of Mycobacterium celatum pulmonary disease in an immunocompetent patient using antimicobacterial chemotherapy and combined pulmonary resection. 2010 Yonsei Med. J. pmid:20879072
Chang JH et al. A case of acute hepatitis with Mycoplasma pneumoniae infection and transient depression of multiple coagulation factors. 2008 Yonsei Med. J. pmid:19108034
Hatipoglu ON and Tasan Y A comparative efficacy and safety study of clarithromycin, roxithromycin and erythromycin stearate in mild pneumonia. 2000 Yonsei Med. J. pmid:10957888
Sim YS et al. Standardized combination antibiotic treatment of Mycobacterium avium complex lung disease. 2010 Yonsei Med. J. pmid:20879056
Lee KY et al. Two cases of acute leukopenia induced by colchicine with concurrent immunosuppressants use in Behçet's disease. 2008 Yonsei Med. J. pmid:18306487
Qin LH and Tang X [Preparation and evaluation of clarithromycin emulsion for injection]. 2006 Yao Xue Xue Bao pmid:17184111
Zhang T et al. [Preparation and evaluation of enteric-coated and taste masking clarithromycin granules]. 2011 Yao Xue Xue Bao pmid:22375429
Ma HL et al. [Polarographic catalytic wave of clarithromycin and its applications]. 2004 Yao Xue Xue Bao pmid:15700824
Wang J et al. [Different concentrations of clarithromycin ophthalmic gel for rabbits corneal ulcers induced by Staphylococcus aureus]. 2008 Yan Ke Xue Bao pmid:18709951
Vakil N Treatment of H. pylori infection: the reality. 1998 Mar-Apr Yale J Biol Med pmid:10378357
Niioka T Clinical usefulness of limited sampling strategies for estimating AUC of proton pump inhibitors. 2011 Yakugaku Zasshi pmid:21372537
Suzuki A et al. [Clinical efficacy of kanamycin for Mycobacterium avium complex disease]. 2008 Yakugaku Zasshi pmid:18311066
Matsuo R et al. [Bitterness of the mixture of clarithromycin dry syrup and carbocisteine preparation--difference between brand name and generic drugs]. 2008 Yakugaku Zasshi pmid:18311069
Omura S et al. [Research and development of clarithromycin]. 1992 Yakugaku Zasshi pmid:1469609
Salimi A et al. Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect. 2016 Xenobiotica pmid:26068526
Pan W et al. Effects of clopidogrel and clarithromycin on the disposition of sibutramine and its active metabolites M1 and M2 in relation to CYP2B6*6 polymorphism. 2013 Xenobiotica pmid:22830954
Kanayama N et al. Drug-drug interactions in the metabolism of imidafenacin: role of the human cytochrome P450 enzymes and UDP-glucuronic acid transferases, and potential of imidafenacin to inhibit human cytochrome P450 enzymes. 2007 Xenobiotica pmid:17484517
Burt HJ et al. IC50-based approaches as an alternative method for assessment of time-dependent inhibition of CYP3A4. 2010 Xenobiotica pmid:20230210
Kubo JI et al. Pharmacokinetic evaluation of high pulmonary disposition of clarithromycin after systemic administration. 2002 Xenobiotica pmid:12419017