clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Stomach Diseases D013272 7 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Skin Neoplasms D012878 12 associated lipids
Colitis D003092 69 associated lipids
Leishmaniasis, Visceral D007898 13 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Braden B The best and worst treatments for Helicobacter pylori. 2015 BMJ pmid:26290321
Li BZ et al. Comparative effectiveness and tolerance of treatments for Helicobacter pylori: systematic review and network meta-analysis. 2015 BMJ pmid:26290044
Haider RB et al. A randomized-controlled study to compare the efficacy of sequential therapy with standard triple therapy for Helicobacter pylori eradication in an Irish population. 2015 Eur J Gastroenterol Hepatol pmid:26287955
Shallom SJ et al. New Real-Time PCR Assays for Detection of Inducible and Acquired Clarithromycin Resistance in the Mycobacterium abscessus Group. 2015 J. Clin. Microbiol. pmid:26269619
Zagari RM et al. Guidelines for the management of Helicobacter pylori infection in Italy: The III Working Group Consensus Report 2015. 2015 Dig Liver Dis pmid:26253555
Sprague J et al. Cutaneous infection with Mycobacterium kansasii in a patient with myelodysplastic syndrome and Sweet syndrome. 2015 Cutis pmid:26244358
Sharara AI et al. Letter: clarithromycin dose for H. pylori therapy remains unresolved--authors' reply. 2015 Aliment. Pharmacol. Ther. pmid:26238584
Graham DY and Gisbert JP Letter: clarithromycin dose for H. pylori therapy remains unresolved. 2015 Aliment. Pharmacol. Ther. pmid:26238583
Honda M et al. Preoperative vs Postoperative Eradication of Helicobacter pylori in 150 Patients with Gastric Cancer: A Randomized Controlled Trial. 2015 J. Am. Coll. Surg. pmid:26141464
Matsumoto T et al. Mycobacterium fortuitum thoracic empyema: A case report and review of the literature. 2015 J. Infect. Chemother. pmid:26139179
Losurdo G et al. Sequential vs. prolonged 14-day triple therapy for Helicobacter pylori eradication: the meta-analysis may be influenced by 'geographical weighting'. 2015 Int. J. Clin. Pract. pmid:26138290
Zhang T Physiologically based pharmacokinetic modeling of disposition and drug-drug interactions for atorvastatin and its metabolites. 2015 Eur J Pharm Sci pmid:26116278
Fraser LA et al. Calcium channel blocker-clarithromycin drug interaction did not increase the risk of nonvertebral fracture: a population-based study. 2015 Ann Pharmacother pmid:25429094
Lee SJ et al. Clarithromycin Attenuates Radiation-Induced Lung Injury in Mice. 2015 PLoS ONE pmid:26114656
Dimer F et al. Inhalable Clarithromycin Microparticles for Treatment of Respiratory Infections. 2015 Pharm. Res. pmid:26113237
Kasai A et al. Prevalence and molecular analysis of macrolide-resistant Moraxella catarrhalis clinical isolates in Japan, following emergence of the highly macrolide-resistant strain NSH1 in 2011. 2015 J. Med. Microbiol. pmid:25934551
Chou HW et al. Risks of cardiac arrhythmia and mortality among patients using new-generation macrolides, fluoroquinolones, and β-lactam/β-lactamase inhibitors: a Taiwanese nationwide study. 2015 Clin. Infect. Dis. pmid:25409476
Mahmoudi A et al. Microbiological assay for the analysis of certain macrolides in pharmaceutical dosage forms. 2015 Int J Pharm pmid:26112961
Flores-Gonzalez JC et al. [Etiology, clinical presentation and outcome of severe viral acute childhood encephalitis (ECOVE study)]. 2015 Rev Neurol pmid:26108903
Jeong BH et al. Intermittent antibiotic therapy for nodular bronchiectatic Mycobacterium avium complex lung disease. 2015 Am. J. Respir. Crit. Care Med. pmid:25393520
Hill FJ et al. From a fish tank injury to hospital haemodialysis: the serious consequences of drug interactions. 2015 BMJ Case Rep pmid:26106178
Yu T et al. Study on clarithromycin lactobionate based dual selector systems for the enantioseparation of basic drugs in capillary electrophoresis. 2015 J Sep Sci pmid:26097042
Tojima I et al. Anti-inflammatory effects of a novel non-antibiotic macrolide, EM900, on mucus secretion of airway epithelium. 2015 Auris Nasus Larynx pmid:25769240
Nonaka L et al. Novel macrolide-resistance genes, mef(C) and mph(G), carried by plasmids from Vibrio and Photobacterium isolated from sediment and seawater of a coastal aquaculture site. 2015 Lett. Appl. Microbiol. pmid:25765542
Koh WJ et al. Response to Switch from Intermittent Therapy to Daily Therapy for Refractory Nodular Bronchiectatic Mycobacterium avium Complex Lung Disease. 2015 Antimicrob. Agents Chemother. pmid:25987622
Tsunemine H et al. [Successful treatment of relapsed and refractory multiple myeloma by using clarithromycin-lenalidomide, low-dose dexamethasone(BiRd), and melphalan-prednisolone(MP)]. 2015 Gan To Kagaku Ryoho pmid:25981655
Ribaldone DG et al. Efficacy of amoxycillin and clarithromycin-based triple therapy for Helicobacter pylori eradication: a 10-year trend in Turin, Italy. 2015 Panminerva Med pmid:25971330
Thellin O et al. In vitro approach to study the synergistic effects of tobramycin and clarithromycin against Pseudomonas aeruginosa biofilms using prokaryotic or eukaryotic culture media. 2015 Int. J. Antimicrob. Agents pmid:25963337
Hwang JJ et al. Efficacy of moxifloxacin-based sequential therapy for first-line eradication of Helicobacter pylori infection in gastrointestinal disease. 2015 World J. Gastroenterol. pmid:25945019
Liou JM et al. The Primary Resistance of Helicobacter pylori in Taiwan after the National Policy to Restrict Antibiotic Consumption and Its Relation to Virulence Factors-A Nationwide Study. 2015 PLoS ONE pmid:25942450
Ferreri AJ et al. High-dose clarithromycin is an active monotherapy for patients with relapsed/refractory extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT): the HD-K phase II trial. 2015 Ann. Oncol. pmid:25935794
Ito A et al. Increase in SCCmec type IV strains affects trends in antibiograms of meticillin-resistant Staphylococcus aureus at a tertiary-care hospital. 2015 J. Med. Microbiol. pmid:25934550
AktaÅŸ B et al. The impact of amalgam dental fillings on the frequency of Helicobacter pylori infection and H. pylori eradication rates in patients treated with concomitant, quadruple, and levofloxacin-based therapies. 2015 Eur J Gastroenterol Hepatol pmid:25919773
Sugawara M et al. Exploration of a standard treatment for Buruli ulcer through a comprehensive analysis of all cases diagnosed in Japan. 2015 J. Dermatol. pmid:25809502
Andrianov M et al. A 15-year-old boy with abdominal pain, growth retardation, and anemia secondary to Helicobacter pylori-associated peptic ulcer. 2015 Pediatr Ann pmid:25806733
Zhao C et al. [Resistance surveillance of major pathogens for adult community-acquired respiratory tract infections in China: a multicenter study 2012]. 2015 Zhonghua Jie He He Hu Xi Za Zhi pmid:25791651
Molina-Infante J et al. Optimised empiric triple and concomitant therapy for Helicobacter pylori eradication in clinical practice: the OPTRICON study. 2015 Aliment. Pharmacol. Ther. pmid:25776067
Takahashi C et al. Observation of antibacterial effect of biodegradable polymeric nanoparticles on Staphylococcus epidermidis biofilm using FE-SEM with an ionic liquid. 2015 Microscopy (Oxf) pmid:25757698
Metanat HA et al. Comparison Between 10- and 14-Day Hybrid Regimens for Helicobacter pylori Eradication: A Randomized Clinical Trial. 2015 Helicobacter pmid:25752357
Essilfie AT et al. Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma. 2015 Thorax pmid:25746630
Bouilhat N et al. High-level primary clarithromycin resistance of Helicobacter pylori in Morocco: a prospective multicenter molecular study. 2015 Helicobacter pmid:25735573
Guzman Vinasco L et al. Acute suppurative parotitis caused by Streptococcus pneumoniae in an HIV-infected man. 2015 BMJ Case Rep pmid:25733094
Mitsui Y et al. Gastric inflammatory fibroid polyp morphologically changed by Helicobacter pylori eradication. 2015 Clin J Gastroenterol pmid:25733031
Ben Chaabane N and Al-Adhba HS Ciprofloxacin-containing versus clarithromycin-containing sequential therapy for Helicobacter pylori eradication: A randomized trial. 2015 Indian J Gastroenterol pmid:25721770
Townsell MY et al. Pathology in practice. Canine distemper virus disease in a dog. 2015 J. Am. Vet. Med. Assoc. pmid:25719842
Zhou Z et al. Macrolide-resistant Mycoplasma pneumoniae in adults in Zhejiang, China. 2015 Antimicrob. Agents Chemother. pmid:25451048
Hur J et al. Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. 2015 Chem. Res. Toxicol. pmid:25811541
Genc G et al. Does systemic clarithromycin therapy have an inhibitory effect on tympanosclerosis? An experimental animal study. 2015 J Laryngol Otol pmid:25619629
Winkel P et al. Clarithromycin for stable coronary heart disease increases all-cause and cardiovascular mortality and cerebrovascular morbidity over 10years in the CLARICOR randomised, blinded clinical trial. 2015 Int. J. Cardiol. pmid:25602299
Trespalacios AA et al. Improved allele-specific PCR assays for detection of clarithromycin and fluoroquinolone resistant of Helicobacter pylori in gastric biopsies: identification of N87I mutation in GyrA. 2015 Diagn. Microbiol. Infect. Dis. pmid:25600075
Yoshida S et al. Investigation of the population structure of Mycobacterium abscessus complex strains using 17-locus variable number tandem repeat typing and the further distinction of Mycobacterium massiliense hsp65 genotypes. 2015 J. Med. Microbiol. pmid:25596119
Ontsira Ngoyi EN et al. Molecular Detection of Helicobacter pylori and its Antimicrobial Resistance in Brazzaville, Congo. 2015 Helicobacter pmid:25585658
Spaniol V et al. Moraxella catarrhalis AcrAB-OprM efflux pump contributes to antimicrobial resistance and is enhanced during cold shock response. 2015 Antimicrob. Agents Chemother. pmid:25583725
Chu HS et al. Nontuberculous mycobacterial ocular infections--comparing the clinical and microbiological characteristics between Mycobacterium abscessus and Mycobacterium massiliense. 2015 PLoS ONE pmid:25581038
Lee HJ et al. Concomitant therapy achieved the best eradication rate for Helicobacter pylori among various treatment strategies. 2015 World J. Gastroenterol. pmid:25574111
Brown-Elliott BA et al. Absence of a functional erm gene in isolates of Mycobacterium immunogenum and the Mycobacterium mucogenicum group, based on in vitro clarithromycin susceptibility. 2015 J. Clin. Microbiol. pmid:25568437
Mourad-Baars PE et al. Low antibiotic resistance of Helicobacter pylori in The Netherlands. 2015 Helicobacter pmid:25495199
Frija-Masson J et al. [Non-tuberculous mycobacterial infection of a totally implanted perfusion device]. 2015 Rev Mal Respir pmid:25480387
Lee H et al. Comparison of efficacy and safety of levofloxacin-containing versus standard sequential therapy in eradication of Helicobacter pylori infection in Korea. 2015 Dig Liver Dis pmid:25467826
Kobayashi M et al. A sudden cardiac death induced by sildenafil and sexual activity in an HIV patient with drug interaction, cardiac early repolarization, and arrhythmogenic right ventricular cardiomyopathy. 2015 Int. J. Cardiol. pmid:25464498
Boltin D et al. Trends in secondary antibiotic resistance of Helicobacter pylori from 2007 to 2014: has the tide turned? 2015 J. Clin. Microbiol. pmid:25428158
Zhang L et al. [Minocycline quadruple versus tailored therapy in retreatment of Helicobacter pylori infection]. 2015 Zhonghua Nei Ke Za Zhi pmid:26887366
Moriya S et al. Targeting the integrated networks of aggresome formation, proteasome, and autophagy potentiates ER stress‑mediated cell death in multiple myeloma cells. 2015 Int. J. Oncol. pmid:25422130
Dierig A et al. Antibiotic treatment of pertussis: are 7 days really sufficient? 2015 Pediatr. Infect. Dis. J. pmid:25247586
Zhang Y et al. Helicobacter pylori, cyclooxygenase-2 and evolution of gastric lesions: results from an intervention trial in China. 2015 Carcinogenesis pmid:26449252
Mailleux M et al. Unusual pulmonary toxicity of ipilimumab treated by macrolides. 2015 Acta Clin Belg pmid:26790556
Gisbert JP et al. Helicobacter pylori first-line and rescue treatments in the presence of penicillin allergy. 2015 Dig. Dis. Sci. pmid:25236423
Ersal T et al. Fatal disseminated infection with Fusarium petroliphilum. 2015 Mycopathologia pmid:25234793
Tongtawee T et al. High Prevalence of Helicobacter pylori Resistance to Clarithromycin: a Hospital-Based Cross-Sectional Study in Nakhon Ratchasima Province, Northeast of Thailand. 2015 Asian Pac. J. Cancer Prev. pmid:26745073
Park JB et al. Modulation of microenvironmental pH and utilization of alkalizers in crystalline solid dispersion for enhanced solubility and stability of clarithromicin. 2015 Arch. Pharm. Res. pmid:25213008
Baumann M et al. Aquatic toxicity of the macrolide antibiotic clarithromycin and its metabolites. 2015 Chemosphere pmid:25051235
Shin SH et al. Helicobacter pylori Eradication Prevents Metachronous Gastric Neoplasms after Endoscopic Resection of Gastric Dysplasia. 2015 PLoS ONE pmid:26580072
Desai S et al. The Epidemiology of Invasive Haemophilus influenzae Non-Serotype B Disease in Ontario, Canada from 2004 to 2013. 2015 PLoS ONE pmid:26569613
Kakked GA et al. Pneumobilia with gastric outlet obstruction. 2015 BMJ Case Rep pmid:26552878
Kim SE et al. Trends in Helicobacter pylori eradication rates by first-line triple therapy and related factors in eradication therapy. 2015 Korean J. Intern. Med. pmid:26552455
Bang CS and Baik GH Time to learn from the past and prepare for the future in Helicobacter pylori eradication. 2015 Korean J. Intern. Med. pmid:26552453
Alimadadi M et al. Impact of creatinine clearance on Helicobacter pylori eradication rate in patients with peptic ulcer disease. 2015 Iran J Kidney Dis pmid:26552348
Karpiński TM et al. Evaluation of antimicrobial resistance of Helicobacter pylori in the last 15 years in West Poland. 2015 Acta Microbiol Immunol Hung pmid:26551571
John A et al. Does emerging Clarithromycin resistance signal an obituary to empirical standard triple therapy for Helicobacter pylori infection? 2015 Indian J Gastroenterol pmid:26541342
Mel-Hennawi D and Ahmed MR Outcome evaluation of clarithromycin, metronidazole and lansoprazole regimens in Helicobacter pylori positive or negative children with resistant otitis media with effusion. 2015 J Laryngol Otol pmid:26521817
Parra D et al. In vitro efficacy of daptomycin and teicoplanin combined with ethanol, clarithromycin or gentamicin as catheter lock solutions. 2015 BMC Microbiol. pmid:26518881
Rose WE et al. Prevention of biofilm formation by methacrylate-based copolymer films loaded with rifampin, clarithromycin, doxycycline alone or in combination. 2015 Pharm. Res. pmid:24934663
Nishizawa T et al. Clarithromycin Versus Metronidazole as First-line Helicobacter pylori Eradication: A Multicenter, Prospective, Randomized Controlled Study in Japan. 2015 J. Clin. Gastroenterol. pmid:24921211
Boyanova L et al. Linezolid susceptibility in Helicobacter pylori, including strains with multidrug resistance. 2015 Int. J. Antimicrob. Agents pmid:26453146
Rubio M et al. Inducible and Acquired Clarithromycin Resistance in the Mycobacterium abscessus Complex. 2015 PLoS ONE pmid:26448181
Blair PW et al. DRESS syndrome presenting after initiation of mycobacterium avium complex osteomyelitis treatment. 2015 BMJ Case Rep pmid:26438676
Chen KY et al. Hybrid vs sequential therapy for eradication of Helicobacter pylori in Taiwan: A prospective randomized trial. 2015 World J. Gastroenterol. pmid:26420970
Apiwattankul N et al. Infections Caused by Rapidly Growing Mycobacteria spp in Children and Adolescents With Cancer. 2015 J Pediatric Infect Dis Soc pmid:26407409
Hwang JJ et al. Efficacy of moxifloxacin-based sequential and hybrid therapy for first-line Helicobacter pylori eradication. 2015 World J. Gastroenterol. pmid:26401089
Weiss S et al. Efficacy of Single and Combined Antibiotic Treatments of Anthrax in Rabbits. 2015 Antimicrob. Agents Chemother. pmid:26392505
Agrawal V et al. A Case of Hypotension and Bradycardia Precipitated by Drug Interaction of Clarithromycin and Calcium-Channel Blocker. 2015 J Am Geriatr Soc pmid:26389998
Hauser G et al. Probiotics for standard triple Helicobacter pylori eradication: a randomized, double-blind, placebo-controlled trial. 2015 Medicine (Baltimore) pmid:25929897
Zhi D et al. The enhancement of cardiac toxicity by concomitant administration of Berberine and macrolides. 2015 Eur J Pharm Sci pmid:25976224
Vliegenthart AD et al. Comprehensive microRNA profiling in acetaminophen toxicity identifies novel circulating biomarkers for human liver and kidney injury. 2015 Sci Rep pmid:26489516
Koide T et al. Analysis of Distribution of Ingredients in Commercially Available Clarithromycin Tablets Using Near-Infrared Chemical Imaging with Principal Component Analysis and Partial Least Squares. 2015 Chem. Pharm. Bull. pmid:26329859
Nozawa K et al. Effect of surfactants or a water soluble polymer on the crystal transition of clarithromycin during a wet granulation process. 2015 Int J Pharm pmid:26325306
Renvoisé A et al. Assessing primary and secondary resistance to clarithromycin and amikacin in infections due to Mycobacterium avium complex. 2015 Antimicrob. Agents Chemother. pmid:26324275
Dingemanse C et al. Akkermansia muciniphila and Helicobacter typhlonius modulate intestinal tumor development in mice. 2015 Carcinogenesis pmid:26320104
Obregón-Henao A et al. Susceptibility of Mycobacterium abscessus to antimycobacterial drugs in preclinical models. 2015 Antimicrob. Agents Chemother. pmid:26303795
Pea F et al. Everolimus overexposure in a heart transplant patient receiving clarithromycin for the treatment of pneumonia. 2015 Transpl Infect Dis pmid:26296391