| MeSH term | MeSH ID | Detail |
|---|---|---|
| Gram-Negative Bacterial Infections | D016905 | 16 associated lipids |
| Angiomatosis, Bacillary | D016917 | 2 associated lipids |
| Meningitis, Bacterial | D016920 | 6 associated lipids |
| Common Variable Immunodeficiency | D017074 | 4 associated lipids |
| AIDS-Related Opportunistic Infections | D017088 | 9 associated lipids |
| IgA Deficiency | D017098 | 2 associated lipids |
| Liver Failure, Acute | D017114 | 11 associated lipids |
| Skin Diseases, Bacterial | D017192 | 8 associated lipids |
| Dermatitis, Phototoxic | D017484 | 4 associated lipids |
| Pityriasis Rosea | D017515 | 3 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Herr H and You CH | Relationship between Helicobacter pylori and rosacea: it may be a myth. | 2000 | J. Korean Med. Sci. | pmid:11068993 |
| Chow LW et al. | Clarithromycin attenuates mastectomy-induced acute inflammatory response. | 2000 | Clin. Diagn. Lab. Immunol. | pmid:11063500 |
| Seppälä K et al. | Cure of Helicobacter pylori infection after failed primary treatment: one-center results from 120 patients. | 2000 | Scand. J. Gastroenterol. | pmid:11063151 |
| Edlund C et al. | Pharmacokinetics and comparative effects of telithromycin (HMR 3647) and clarithromycin on the oropharyngeal and intestinal microflora. | 2000 | J. Antimicrob. Chemother. | pmid:11062193 |
| Bhasin DK et al. | Drug resistance in Helicobacter pylori infection. | 2000 | Indian J Gastroenterol | pmid:11060974 |
| Giannini E et al. | Influence of Helicobacter pylori eradication therapy on 13C aminopyrine breath test: comparison among omeprazole-, lansoprazole-, or pantoprazole-containing regimens. | 2000 | Am. J. Gastroenterol. | pmid:11051345 |
| Kelley MA et al. | Breakthrough pneumococcal bacteremia in patients being treated with azithromycin and clarithromycin. | 2000 | Clin. Infect. Dis. | pmid:11049784 |
| Frank F et al. | Helicobacter pylori infection in recurrent abdominal pain. | 2000 | J. Pediatr. Gastroenterol. Nutr. | pmid:11045841 |
| McWhinney PH et al. | Failure to produce detectable antibodies to Legionella pneumophila by an immunocompetent adult. | 2000 | J. Infect. | pmid:11041710 |
| Rea TH | Trials of daily, long-term minocycline and rifampin or clarithromycin and rifampin in the treatment of borderline lepromatous and lepromatous leprosy. | 2000 | Int. J. Lepr. Other Mycobact. Dis. | pmid:11036492 |
| Giacometti A et al. | In-vitro activity and killing effect of polycationic peptides on methicillin-resistant Staphylococcus aureus and interactions with clinically used antibiotics. | 2000 | Diagn. Microbiol. Infect. Dis. | pmid:11035243 |
| Giacometti A et al. | Combination studies between polycationic peptides and clinically used antibiotics against Gram-positive and Gram-negative bacteria. | 2000 | Peptides | pmid:11035200 |
| Goh K et al. | Efficacy of a 1-week pantoprazole triple therapy in eradicating Helicobacter pylori in Asian patients. | 2000 | J. Gastroenterol. Hepatol. | pmid:11022833 |
| Umegaki N et al. | Clarithromycin-resistance and point mutations in the 23S rRNA gene in Helicobacter pylori isolates from Japan. | 2000 | J. Gastroenterol. Hepatol. | pmid:11022832 |
| Cammarota G et al. | Six-day therapy with ranitidine bismuth citrate plus low-dose clarithromycin and tinidazole to cure Helicobacter pylori infection. | 2000 Jul-Aug | Hepatogastroenterology | pmid:11020908 |
| Guyot A et al. | Clarithromycin appears to be linked with Clostridium difficile-associated diarrhoea in the elderly. | 2000 | J. Antimicrob. Chemother. | pmid:11020269 |
| Alarcón T et al. | Clarithromycin resistance stability in Helicobacter pylori: influence of the MIC and type of mutation in the 23S rRNA. | 2000 | J. Antimicrob. Chemother. | pmid:11020260 |
| Cirioni O et al. | Inhibition of growth of Pneumocystis carinii by lactoferrins alone and in combination with pyrimethamine, clarithromycin and minocycline. | 2000 | J. Antimicrob. Chemother. | pmid:11020255 |
| Kuper JI and D'Aprile M | Drug-Drug interactions of clinical significance in the treatment of patients with Mycobacterium avium complex disease. | 2000 | Clin Pharmacokinet | pmid:11020135 |
| Lamouliatte H et al. | [Treatment of Helicobacter pylori infection]. | 2000 | Rev Prat | pmid:11019637 |
| Saint-Blancard P et al. | [Cutaneous nodular infection with hemopathy]. | 2000 | Ann Pathol | pmid:11015652 |
| Wolfe J et al. | Mycobacterium branderi from both a hand infection and a case of pulmonary disease. | 2000 | J. Clin. Microbiol. | pmid:11015432 |
| Makristathis A et al. | Two enzyme immunoassays and PCR for detection of Helicobacter pylori in stool specimens from pediatric patients before and after eradication therapy. | 2000 | J. Clin. Microbiol. | pmid:11015388 |
| Alter P et al. | [Impediment of cellular immune response under treatment with ticlopidine in a patient with Staphylococcus aureus endocarditis]. | 2000 | Z Kardiol | pmid:11013974 |
| Yanagihara K et al. | Intrapulmonary concentrations of inflammatory cytokines in a mouse model of chronic respiratory infection caused by Pseudomonas aeruginosa. | 2000 | Clin. Exp. Immunol. | pmid:11012620 |
| Westphal JF | Macrolide - induced clinically relevant drug interactions with cytochrome P-450A (CYP) 3A4: an update focused on clarithromycin, azithromycin and dirithromycin. | 2000 | Br J Clin Pharmacol | pmid:11012550 |
| Gomollón F et al. | Third line treatment for Helicobacter pylori: a prospective, culture-guided study in peptic ulcer patients. | 2000 | Aliment. Pharmacol. Ther. | pmid:11012479 |
| Catalano F et al. | Helicobacter pylori-positive duodenal ulcer: three-day antibiotic eradication regimen. | 2000 | Aliment. Pharmacol. Ther. | pmid:11012478 |
| Gisbert JP et al. | Proton pump inhibitor, clarithromycin and either amoxycillin or nitroimidazole: a meta-analysis of eradication of Helicobacter pylori. | 2000 | Aliment. Pharmacol. Ther. | pmid:11012477 |
| Bermejo F et al. | [Effects of Helicobacter pylori eradication on the recurrence of gastric ulcer during a 12-month follow up]. | 2000 | Med Clin (Barc) | pmid:11002456 |
| Shimizu T et al. | Case of intrafamilial Helicobacter pylori reinfection after successful eradication therapy. | 2000 | Pediatr. Infect. Dis. J. | pmid:11001123 |
| Huang AH et al. | Impact of Helicobacter pylori antimicrobial resistance on the outcome of 1-week lansoprazole-based triple therapy. | 2000 | J. Formos. Med. Assoc. | pmid:11000734 |
| Mushiroda T et al. | The involvement of flavin-containing monooxygenase but not CYP3A4 in metabolism of itopride hydrochloride, a gastroprokinetic agent: comparison with cisapride and mosapride citrate. | 2000 | Drug Metab. Dispos. | pmid:10997945 |
| Testoni PA and Bagnolo F | In dyspeptic patients without gastric phase III of the migrating motor complex, Helicobacter pylori eradication produces no short-term changes in interdigestive motility pattern. | 2000 | Scand. J. Gastroenterol. | pmid:10994618 |
| Catalano F et al. | Five-day triple therapy in Helicobacter pylori-positive duodenal ulcer: an eighteen-month follow-up. | 2000 | J. Clin. Gastroenterol. | pmid:10993428 |
| Howden CW | Treatment of Helicobacter pylori infection: is less more? | 2000 | J. Clin. Gastroenterol. | pmid:10993423 |
| Cynamon MH et al. | Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model. | 2000 | Antimicrob. Agents Chemother. | pmid:10991883 |
| Rastogi N et al. | In vitro activities of the ketolides telithromycin (HMR 3647) and HMR 3004 compared to those of clarithromycin against slowly growing mycobacteria at pHs 6.8 and 7.4. | 2000 | Antimicrob. Agents Chemother. | pmid:10991870 |
| Ohtani H et al. | Comparative pharmacodynamic analysis of Q-T interval prolongation induced by the macrolides clarithromycin, roxithromycin, and azithromycin in rats. | 2000 | Antimicrob. Agents Chemother. | pmid:10991836 |
| Bermudez LE et al. | Clarithromycin-resistant mycobacterium avium is still susceptible to treatment with clarithromycin and is virulent in mice. | 2000 | Antimicrob. Agents Chemother. | pmid:10991834 |
| Hentschel E | [Treatment of Helicobacter pylori infections]. | 2000 | Acta Med. Austriaca | pmid:10989677 |
| Komine M and Tamaki K | An open trial of oral macrolide treatment for psoriasis vulgaris. | 2000 | J. Dermatol. | pmid:10989574 |
| Denis A et al. | Beta-keto-ester chemistry and ketolides. Synthesis and antibacterial activity of 2-halogeno, 2-methyl and 2,3 enol-ether ketolides. | 2000 | Bioorg. Med. Chem. Lett. | pmid:10987440 |
| Bosne-David S et al. | Intrinsic resistance of Mycobacterium tuberculosis to clarithromycin is effectively reversed by subinhibitory concentrations of cell wall inhibitors. | 2000 | J. Antimicrob. Chemother. | pmid:10980165 |
| Sohn YT et al. | Polymorphism of clarithromycin. | 2000 | Arch. Pharm. Res. | pmid:10976587 |
| Buzás György M et al. | [Lansoprazole versus ranitidine bismuth citrate containing triple regimens for Helicobacter pylori eradication in patients with duodenal ulcer]. | 2000 | Orv Hetil | pmid:10976194 |
| Scuderi G et al. | Helicobacter pylori: use of a stool antigen detection test and a six-day triple therapy. | 2000 Jan-Feb | Dig Liver Dis | pmid:10975761 |
| Cattoli G et al. | Helicobacter acinonychis eradication leading to the resolution of gastric lesions in tigers. | 2000 | Vet. Rec. | pmid:10975334 |
| Colin AA | Eradication of mycobacterium abscessus in a chronically infected patient with cystic fibrosis. | 2000 | Pediatr. Pulmonol. | pmid:10973047 |
| Frevel M et al. | Eradication of Helicobacter pylori with pantoprazole and two antibiotics: a comparison of two short-term regimens. | 2000 | Aliment. Pharmacol. Ther. | pmid:10971231 |