clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Hyperemesis Gravidarum D006939 2 associated lipids
Empyema, Pleural D016724 2 associated lipids
Mastoiditis D008417 2 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Scrub Typhus D012612 3 associated lipids
Tuberculosis, Avian D014379 2 associated lipids
Typhoid Fever D014435 2 associated lipids
Central Nervous System Protozoal Infections D020808 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Berg-Candolfi M and Candolfi E Depression of the N-demethylation of erythromycin, azithromycin, clarithromycin and clindamycin in murine Toxoplasma infection. 1996 Int. J. Parasitol. pmid:9024879
Griffith DE et al. Varying dosages of rifabutin affect white blood cell and platelet counts in human immunodeficiency virus--negative patients who are receiving multidrug regimens for pulmonary Mycobacterium avium complex disease. 1996 Clin. Infect. Dis. pmid:8953085
Dalla Libera M et al. High effectiveness and safety of one-week antibiotic regimen in Helicobacter pylori eradication. 1996 Aliment. Pharmacol. Ther. pmid:8730251
Labenz J et al. One-week triple therapy with omeprazole, amoxycillin and either clarithromycin or metronidazole for cure of Helicobacter pylori infection. 1996 Aliment. Pharmacol. Ther. pmid:8730252
Pellegrin I et al. Activity of rifabutin, clarithromycin, ethambutol, sparfloxacin and amikacin, alone and in combination, against Mycobacterium avium complex in human macrophages. 1996 J. Antimicrob. Chemother. pmid:9182107
Matsuoka N et al. Inhibitory effect of clarithromycin on costimulatory molecule expression and cytokine production by synovial fibroblast-like cells. 1996 Clin. Exp. Immunol. pmid:9099936
van der Hulst RW et al. Therapeutic options after failed Helicobacter pylori eradication therapy. 1996 Am. J. Gastroenterol. pmid:8931413
Alder JD et al. Relevance of the ferret model of Helicobacter-induced gastritis to evaluation of antibacterial therapies. 1996 Am. J. Gastroenterol. pmid:8931416
Kuo CC et al. In vitro activities of azithromycin, clarithromycin, and other antibiotics against Chlamydia pneumoniae. 1996 Antimicrob. Agents Chemother. pmid:8913488
Aoyama T et al. Efficacy of short-term treatment of pertussis with clarithromycin and azithromycin. 1996 J. Pediatr. pmid:8917247
Koeck JL et al. Disseminated Mycobacterium simiae infection in a patient with AIDS: clinical features and treatment. 1996 Clin. Infect. Dis. pmid:8909856
Liviu L et al. Pancreatitis induced by clarithromycin. 1996 Ann. Intern. Med. pmid:8849171
Ramirez Mayans JA et al. [Elimination of Helicobacter pylori in patients with recurrent abdominal pain with simultaneous administration of ranitidine, bismuth subsalicylate and clarithromycin]. 1996 Acta Gastroenterol. Latinoam. pmid:9363265
Cammarota G et al. Helicobacter pylori eradication using one-week low-dose lansoprazole plus amoxycillin and either clarithromycin or azithromycin. 1996 Aliment. Pharmacol. Ther. pmid:8971300
Pilotto A et al. Cure of Helicobacter pylori infection in the elderly: effects of eradication on gastritis and serological markers. 1996 Aliment. Pharmacol. Ther. pmid:8971305
Adachi T et al. Eosinophil apoptosis caused by theophylline, glucocorticoids, and macrolides after stimulation with IL-5. 1996 J. Allergy Clin. Immunol. pmid:8977529
Murakami K et al. Atopic dermatitis successfully treated by eradication of Helicobacter pylori. 1996 J. Gastroenterol. pmid:8959527
Diemer PR et al. [Rifabutin-induced hypopyon iritis in HIV infection]. 1996 Klin Monbl Augenheilkd pmid:8965476
Labenz J [Current developments in Helicobacter pylori therapy]. 1996 Leber Magen Darm pmid:8965606
Grau E et al. Interaction between clarithromycin and oral anticoagulants. 1996 Ann Pharmacother pmid:8968465
Muñoz N et al. Chemoprevention trial on precancerous lesions of the stomach in Venezuela: summary of study design and baseline data. 1996 IARC Sci. Publ. pmid:8923024
Dhaenens L et al. In-vitro activities of clarithromycin and other antimicrobial agents against Helicobacter pylori isolated from children. 1996 J. Antimicrob. Chemother. pmid:8877551
Tursi A et al. Helicobacter pylori eradication helps resolve pyloric and duodenal stenosis. 1996 J. Clin. Gastroenterol. pmid:8877648
Thor P et al. Dysfunction in gastric myoelectric and motor activity in Helicobacter pylori positive gastritis patients with non-ulcer dyspesia. 1996 J. Physiol. Pharmacol. pmid:8877902
Ji B et al. Bactericidal activity of single dose of clarithromycin plus minocycline, with or without ofloxacin, against Mycobacterium leprae in patients. 1996 Antimicrob. Agents Chemother. pmid:8878595
Chen S et al. [Omeprazole, clarithromycin and amoxicillin therapy for Helicobacter pylori infection]. 1996 Zhonghua Nei Ke Za Zhi pmid:9592303
Liu W et al. [Clarithromycin combined short-term triple therapies for eradication of Helicobacter pylori infection]. 1996 Zhonghua Nei Ke Za Zhi pmid:9592304
Tursi A et al. Short-term low-dose triple therapy with lansoprazole plus amoxycillin and clarithromycin for Helicobacter pylori eradication. 1996 Am. J. Gastroenterol. pmid:8759696
Debets-Ossenkopp YJ et al. Mechanism of clarithromycin resistance in clinical isolates of Helicobacter pylori. 1996 FEMS Microbiol. Lett. pmid:8759787
Géhanno P et al. [Clarithromycin versus amoxicillin-clavulanic acid in the treatment of acute maxillary sinusitis in adults]. 1996 Pathol. Biol. pmid:8763594
Jordan WC Clarithromycin prophylaxis against Cryptosporidium enteritis in patients with AIDS. 1996 J Natl Med Assoc pmid:8764523
Xu G et al. [Effect of clarithromycin on cytocidal activity against Pseudomonas aeruginosa in mice peritoneal cavity]. 1996 Kansenshogaku Zasshi pmid:8822058
Pijpers E et al. A clarithromycin-induced myasthenic syndrome. 1996 Clin. Infect. Dis. pmid:8824993
Webb DD Practice guidelines for treatment of peptic ulcer disease. 1996 JAMA pmid:8827959
Three new studies expand understanding of MAC therapy. 1996 Am J Health Syst Pharm pmid:8899122
Riff DS et al. Triple therapy with lansoprazole, clarithromycin, and amoxicillin for the cure of Helicobacter pylori infection: a short report. 1996 Helicobacter pmid:9398874
Harford W et al. Double-blind, multicenter evaluation of lansoprazole and amoxicillin dual therapy for the cure of Helicobacter pylori infection. 1996 Helicobacter pmid:9398875
Schwartz H et al. Seven-day triple therapy with lansoprazole, clarithromycin, and metronidazole for the cure of Helicobacter pylori infection: a short report. 1996 Helicobacter pmid:9398876
Jaup BK Duodenal ulcer healing after 7-day treatment: a pilot study with lansoprazole, amoxicillin, and clarithromycin. 1996 Helicobacter pmid:9398878
Moayyedi P et al. Comparison of one or two weeks of lansoprazole, amoxicillin, and clarithromycin in the treatment of Helicobacter pylori. 1996 Helicobacter pmid:9398880
Mégraud F and Malfertheiner P Treatment of Helicobacter pylori infection: summary of a meeting at the Fourth United European Gastroenterology Week, September 20, 1995. 1996 Helicobacter pmid:9398889
O'Morain C et al. Double-blind, multicenter, placebo-controlled evaluation of clarithromycin and omeprazole for Helicobacter pylori-associated duodenal ulcer. 1996 Helicobacter pmid:9398893
Deltenre M et al. [How to eradicate Helicobacter pylori in 1995? Critical review of available treatments]. 1996 Gastroenterol. Clin. Biol. pmid:8734370
Cayla R [How to eradicate Helicobacter pylori?]. 1996 Gastroenterol. Clin. Biol. pmid:8734380
Koga T et al. In-vitro and in-vivo antibacterial activity of plaunotol, a cytoprotective antiulcer agent, against Helicobacter pylori. 1996 J. Antimicrob. Chemother. pmid:8737142
Lebrun L et al. Evaluation of the Etest for rapid susceptibility testing of Mycobacterium avium to clarithromycin. 1996 J. Antimicrob. Chemother. pmid:8737150
Markham A and McTavish D Clarithromycin and omeprazole as helicobacter pylori eradication therapy in patients with H. pylori-associated gastric disorders. 1996 Drugs pmid:8741237
Unge P Review of Helicobacter pylori eradication regimens. 1996 Scand. J. Gastroenterol. Suppl. pmid:8722388
Bazzoli F Italian omeprazole triple therapy--a 1-week regimen. 1996 Scand. J. Gastroenterol. Suppl. pmid:8722395
Goddard AF and Logan RP Antimicrobial resistance and Helicobacter pylori. 1996 J. Antimicrob. Chemother. pmid:8722530