| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hyperemesis Gravidarum | D006939 | 2 associated lipids |
| Empyema, Pleural | D016724 | 2 associated lipids |
| Mastoiditis | D008417 | 2 associated lipids |
| Pityriasis Rosea | D017515 | 3 associated lipids |
| Duodenogastric Reflux | D004383 | 2 associated lipids |
| Tuberculosis, Multidrug-Resistant | D018088 | 6 associated lipids |
| Scrub Typhus | D012612 | 3 associated lipids |
| Tuberculosis, Avian | D014379 | 2 associated lipids |
| Typhoid Fever | D014435 | 2 associated lipids |
| Central Nervous System Protozoal Infections | D020808 | 3 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tietz A et al. | Fulminant liver failure associated with clarithromycin. | 2003 | Ann Pharmacother | pmid:12503933 |
| Grunden JW and Fisher KA | Lovastatin-induced rhabdomyolysis possibly associated with clarithromycin and azithromycin. | 1997 Jul-Aug | Ann Pharmacother | pmid:9220046 |
| Fraser LA et al. | Calcium channel blocker-clarithromycin drug interaction did not increase the risk of nonvertebral fracture: a population-based study. | 2015 | Ann Pharmacother | pmid:25429094 |
| Wintermeyer SM et al. | Dirithromycin: a new macrolide. | 1996 | Ann Pharmacother | pmid:8893122 |
| Marra F et al. | A comparison of antibiotic use in children between Canada and Denmark. | 2007 | Ann Pharmacother | pmid:17374628 |
| Juurlink DN and Ito S | Comment: clarithromycin-digoxin interaction. | 1999 | Ann Pharmacother | pmid:10630847 |
| Rao KB et al. | Enhanced hypoprothrombinemia with warfarin due to azithromycin. | 2004 | Ann Pharmacother | pmid:15084685 |
| Sipe BE et al. | Rhabdomyolysis causing AV blockade due to possible atorvastatin, esomeprazole, and clarithromycin interaction. | 2003 | Ann Pharmacother | pmid:12773066 |
| Basyigit I et al. | The effect of clarithromycin on inflammatory markers in chronic obstructive pulmonary disease: preliminary data. | 2004 | Ann Pharmacother | pmid:15252191 |
| De Bruin ML et al. | Use of cisapride with contraindicated drugs in The Netherlands. | 2002 | Ann Pharmacother | pmid:11847959 |
| Varner TR et al. | Role of rifampin-based combination therapy for severe community-acquired Legionella pneumophila pneumonia. | 2011 | Ann Pharmacother | pmid:21775694 |
| Courter JD et al. | Increased clinical failures when treating acute otitis media with macrolides: a meta-analysis. | 2010 | Ann Pharmacother | pmid:20150506 |
| Pollak PT et al. | Delirium probably induced by clarithromycin in a patient receiving fluoxetine. | 1995 | Ann Pharmacother | pmid:7655131 |
| Bahal N and Nahata MC | The new macrolide antibiotics: azithromycin, clarithromycin, dirithromycin, and roxithromycin. | 1992 | Ann Pharmacother | pmid:1318761 |
| Ibrahim RB et al. | Tacrolimus-clarithromycin interaction in a patient receiving bone marrow transplantation. | 2002 | Ann Pharmacother | pmid:12452763 |
| Tseng AL and Walmsley SL | Rifabutin-associated uveitis. | 1995 | Ann Pharmacother | pmid:8573961 |
| González Carro P et al. | Acute pancreatitis and modified-release clarithromycin. | 2004 | Ann Pharmacother | pmid:14755067 |
| Tanaka H et al. | Effect of clarithromycin on steady-state digoxin concentrations. | 2003 | Ann Pharmacother | pmid:12549942 |
| Yano R et al. | Evaluation of potential interaction between vinorelbine and clarithromycin. | 2009 | Ann Pharmacother | pmid:19261952 |
| Gavura SR and Nusinowitz S | Leukocytoclastic vasculitis associated with clarithromycin. | 1998 | Ann Pharmacother | pmid:9606474 |
| Lee AJ and Maddix DS | Rhabdomyolysis secondary to a drug interaction between simvastatin and clarithromycin. | 2001 | Ann Pharmacother | pmid:11197581 |
| Tracy TS and Johns M | Comment: delirium probably induced by clarithromycin in a patient receiving fluoxetine. | 1996 | Ann Pharmacother | pmid:8893135 |
| Rapp RP et al. | New macrolide antibiotics: usefulness in infections caused by mycobacteria other than Mycobacterium tuberculosis. | 1994 | Ann Pharmacother | pmid:7849341 |
| Sungur C | Acute rheumatic fever despite clarithromycin treatment of beta-hemolytic streptococcal tonsillitis. | 1994 | Ann Pharmacother | pmid:7841580 |
| Chouhan UM et al. | Simvastatin interaction with clarithromycin and amiodarone causing myositis. | 2005 | Ann Pharmacother | pmid:16159992 |
| Widgerow AD et al. | Atypical Mycobacterium and breast surgery. | 1995 | Ann Plast Surg | pmid:7486746 |
| Issa H et al. | Bleeding duodenal ulcer after Roux-en-Y gastric bypass surgery: the value of laparoscopic gastroduodenoscopy. | Ann Saudi Med | pmid:20103961 | |
| Varghese B et al. | First case report of chronic pulmonary lung disease caused by Mycobacterium abscessus in two immunocompetent patients in Saudi Arabia. | Ann Saudi Med | pmid:22588446 | |
| Moosavian M et al. | Rapid detection of clarithromycin-resistant Helicobacter pylori in patients with dyspepsia by fluorescent in situ hybridization (FISH) compared with the E-test. | 2007 Mar-Apr | Ann Saudi Med | pmid:17356313 |
| Al-Benwan K et al. | Diagnosis of endocarditis caused by Mycobacterium abscessus. | 2010 Sep-Oct | Ann Saudi Med | pmid:20697162 |
| Kikuchi R et al. | A case of Good's syndrome: a rare acquired immunodeficiency associated with thymoma. | 2011 | Ann Thorac Cardiovasc Surg | pmid:21587135 |
| Wali S | Mycobacterium chelonae empyema with bronchopleural fistula in an immunocompetent patient. | 2009 | Ann Thorac Med | pmid:19881169 |
| Tanih NF et al. | Characterisation of the genes encoding resistance to metronidazole (rdxA and frxA) and clarithromycin (the 23S-rRNA genes) in South African isolates of Helicobacter pylori. | 2011 | Ann Trop Med Parasitol | pmid:21801504 |
| Tan HH et al. | Cutaneous Mycobacterium haemophilum infections in immunocompromised patients in a dermatology clinic in Singapore. | 2004 | Ann. Acad. Med. Singap. | pmid:15329772 |
| Lee HY et al. | Unresolving furunculosis in a diabetic patient: cutaneous Mycobacterium abscessus infection. | 2009 | Ann. Acad. Med. Singap. | pmid:19271048 |
| Amayasu H et al. | Clarithromycin suppresses bronchial hyperresponsiveness associated with eosinophilic inflammation in patients with asthma. | 2000 | Ann. Allergy Asthma Immunol. | pmid:10875487 |
| Dubini M et al. | Multiple drug allergy: A case of anaphylaxis to levofloxacin but tolerance to ciprofloxacin. | 2016 | Ann. Allergy Asthma Immunol. | pmid:27009438 |
| Fonseca-Aten M et al. | Effect of clarithromycin on cytokines and chemokines in children with an acute exacerbation of recurrent wheezing: a double-blind, randomized, placebo-controlled trial. | 2006 | Ann. Allergy Asthma Immunol. | pmid:17069099 |
| Hahn DL et al. | Evidence for Chlamydia pneumoniae infection in steroid-dependent asthma. | 1998 | Ann. Allergy Asthma Immunol. | pmid:9475566 |
| Swamy N et al. | Successful clarithromycin desensitization in a multiple macrolide-allergic patient. | 2010 | Ann. Allergy Asthma Immunol. | pmid:21130389 |
| McCarty JM and Pierce PF | Five days of cefprozil versus 10 days of clarithromycin in the treatment of an acute exacerbation of chronic bronchitis. | 2001 | Ann. Allergy Asthma Immunol. | pmid:11686426 |
| Spahn JD et al. | Clarithromycin potentiates glucocorticoid responsiveness in patients with asthma: results of a pilot study. | 2001 | Ann. Allergy Asthma Immunol. | pmid:11770698 |
| Mori F et al. | Sensitivity and specificity of skin tests in the diagnosis of clarithromycin allergy. | 2010 | Ann. Allergy Asthma Immunol. | pmid:20486332 |
| Morisset J et al. | A case of difficult-to-treat eosinophilic asthma controlled with clarithromycin. | 2012 | Ann. Allergy Asthma Immunol. | pmid:22727169 |
| Randhawa I and Klaustermeyer WB | Oral corticosteroid-dependent asthma: a 30-year review. | 2007 | Ann. Allergy Asthma Immunol. | pmid:17941275 |
| Sevin E et al. | [Helicobacter pylori: identification and detection of clarithromycin resistance by gene amplification]. | 2000 Jan-Feb | Ann. Biol. Clin. (Paris) | pmid:10673617 |
| Heifets L et al. | Capreomycin is active against non-replicating M. tuberculosis. | 2005 | Ann. Clin. Microbiol. Antimicrob. | pmid:15804353 |
| Destura RV et al. | Laboratory diagnosis and susceptibility profile of Helicobacter pylori infection in the Philippines. | 2004 | Ann. Clin. Microbiol. Antimicrob. | pmid:15546485 |
| Seck A et al. | Primary antibiotic resistance and associated mechanisms in Helicobacter pylori isolates from Senegalese patients. | 2013 | Ann. Clin. Microbiol. Antimicrob. | pmid:23298145 |
| Ribeiro ML et al. | Mutations in the 23S rRNA gene are associated with clarithromycin resistance in Helicobacter pylori isolates in Brazil. | 2003 | Ann. Clin. Microbiol. Antimicrob. | pmid:14633281 |