clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Hyperemesis Gravidarum D006939 2 associated lipids
Empyema, Pleural D016724 2 associated lipids
Mastoiditis D008417 2 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Scrub Typhus D012612 3 associated lipids
Tuberculosis, Avian D014379 2 associated lipids
Typhoid Fever D014435 2 associated lipids
Central Nervous System Protozoal Infections D020808 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Yakoob J et al. Antibiotic susceptibility of Helicobacter pylori in the Chinese population. 2001 J. Gastroenterol. Hepatol. pmid:11595061
Keto Y et al. Gastric mucosal changes induced by long term infection with Helicobacter pylori in Mongolian gerbils: effects of bacteria eradication. 2001 Jan-Dec J. Physiol. Paris pmid:11595471
Buzás GM et al. Six regimens for the eradication of Helicobacter pylori (Hp) in duodenal ulcer patients: three consecutive trials (1995-1999). J. Physiol. Paris pmid:11595472
Chahine C et al. Ultrashort regimen of lansoprazole-amoxicillin-azithromycin for eradicating Helicobacter pylori. 2001 Am J Health Syst Pharm pmid:11596697
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Hyde TB et al. Macrolide resistance among invasive Streptococcus pneumoniae isolates. 2001 JAMA pmid:11597287
Ling KL et al. Efficacy of a nitroimidazole containing tripletherapy regime in Singapore. 2001 Singapore Med J pmid:11599627
Lounis N et al. Efficacies of clarithromycin regimens against Mycobacterium xenopi in mice. 2001 Antimicrob. Agents Chemother. pmid:11600387
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Gikas A et al. In vitro susceptibility of Coxiella burnetii to linezolid in comparison with its susceptibilities to quinolones, doxycycline, and clarithromycin. 2001 Antimicrob. Agents Chemother. pmid:11600400
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Tankovic J et al. Clarithromycin resistance of Helicobacter pylori has a major impact on the efficacy of the omeprazole-amoxicillin-clarithromycin therapy. 2001 Pathol. Biol. pmid:11642014
Timm S et al. First successful treatment of a primary high-grade gastric MALT lymphoma by eradication therapy for Helicobacter pylori. 2001 Gastroenterology pmid:11665693
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Ozen H et al. Helicobacter pylori infection and recurrent abdominal pain in Turkish children. 2001 Helicobacter pmid:11683926
McNulty CA et al. A pilot study to determine the effectiveness of garlic oil capsules in the treatment of dyspeptic patients with Helicobacter pylori. 2001 Helicobacter pmid:11683929
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Vichev E et al. [Gastroduodenitis and ulcers--statistical study for 1998]. 2000 Vutr Boles pmid:11688321
Stratchounski LS et al. Antimicrobial susceptibility of nasopharyngeal isolates of Haemophilus influenzae from healthy children in day-care centres: results of multicentre study in Russia. 2001 Int. J. Antimicrob. Agents pmid:11691567
Zheng X et al. Clinical isolates of Streptococcus pneumoniae resistant to levofloxacin contain mutations in both gyrA and parC genes. 2001 Int. J. Antimicrob. Agents pmid:11691571
Dzierzanowska-Fangrat K et al. Primary resistance to clarithromycin in clinical strains of Helicobacter pylori isolated from children in Poland. 2001 Int. J. Antimicrob. Agents pmid:11691574
Dandekar SS and Laidlaw DA Suprachoroidal haemorrhage after addition of clarithromycin to warfarin. 2001 J R Soc Med pmid:11691898
Gisbert JP et al. Helicobacter pylori eradication therapy is more effective in peptic ulcer than in non-ulcer dyspepsia. 2001 Eur J Gastroenterol Hepatol pmid:11692055
Mayr-Kanhäuser S et al. Resolution of granulomatous rosacea after eradication of Helicobacter pylori with clarithromycin, metronidazole and pantoprazole. 2001 Eur J Gastroenterol Hepatol pmid:11692067
Horsburgh CR et al. Disseminated Mycobacterium avium complex disease among patients infected with human immunodeficiency virus, 1985-2000. 2001 Clin. Infect. Dis. pmid:11692307
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Chai D et al. [Effect of macrolides on biofilm of mucoid Pseudomonas aeruginosa]. 2001 Zhonghua Yi Xue Za Zhi pmid:11702671
Ena P et al. Rapid identification of cutaneous infections by nontubercular mycobacteria by polymerase chain reaction-restriction analysis length polymorphism of the hsp65 gene. 2001 Int. J. Dermatol. pmid:11703519
Carabias ML et al. [Are the antimicrobials used in community-acquired respiratory infection useful for preventing transmission of meningococcal disease? In vitro study]. 2001 Rev Esp Quimioter pmid:11704772
Okano A et al. Subcutaneous infection with Mycobacterium fortuitum after allogeneic bone marrow transplantation. 2001 Bone Marrow Transplant. pmid:11704796
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Komori T et al. Up-regulation by clarithromycin of alpha(1)-acid glycoprotein expression in liver and primary cultured hepatocytes. 2001 Biochem. Pharmacol. pmid:11709199
Endo H et al. Effects of lansoprazole and amoxicillin on uptake of [(14)C]clarithromycin into gastric tissue in rats. 2001 Antimicrob. Agents Chemother. pmid:11709323