clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

Cross Reference

Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Hyperemesis Gravidarum D006939 2 associated lipids
Empyema, Pleural D016724 2 associated lipids
Mastoiditis D008417 2 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Scrub Typhus D012612 3 associated lipids
Tuberculosis, Avian D014379 2 associated lipids
Typhoid Fever D014435 2 associated lipids
Central Nervous System Protozoal Infections D020808 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Choi SJ et al. Column-switching high-performance liquid chromatographic determination of clarithromycin in human plasma with electrochemical detection. 2001 Talanta pmid:18968261
Li W et al. Determination of clarithromycin in rat plasma by HPLC-UV method with pre-column derivatization. 2007 Talanta pmid:19071316
Vu DH et al. Simultaneous determination of rifampicin, clarithromycin and their metabolites in dried blood spots using LC-MS/MS. 2014 Talanta pmid:24607103
Moayyedi P and Murphy B Helicobacter pylori: a clinical update. 2001 Symp Ser Soc Appl Microbiol pmid:11422568
Kusters JG and Kuipers EJ Antibiotic resistance of Helicobacter pylori. 2001 Symp Ser Soc Appl Microbiol pmid:11422569
Schulzke S et al. Mycobacterium bohemicum--a cause of paediatric cervical lymphadenitis. 2004 Swiss Med Wkly pmid:15190440
Piso RJ et al. Coverage of atypical pathogens for hospitalised patients with community-acquired pneumonia is not guided by clinical parameters. 2013 Swiss Med Wkly pmid:24089030
Wang B et al. In-vitro characterisation of a novel antimicrobial agent, TNP-2092, against Helicobacter pylori clinical isolates. Swiss Med Wkly pmid:30044468
Soltermann A et al. Assessment of Helicobacter pylori clarithromycin resistance mutations in archival gastric biopsy samples. 2005 Swiss Med Wkly pmid:16034687
Cone LA et al. Delirium in the elderly resulting from azithromycin therapy. 2003 Surg Neurol pmid:12826358
Nzeako BC and Al-Namaani F The antibacterial activity of honey on helicobacter pylori. 2006 Sultan Qaboos Univ Med J pmid:21748138
Lee HY et al. Survey of methadone-drug interactions among patients of methadone maintenance treatment program in Taiwan. 2012 Subst Abuse Treat Prev Policy pmid:22429858
Earl AM et al. High quality draft genome sequence of Segniliparus rugosus CDC 945(T)= (ATCC BAA-974(T)). 2011 Stand Genomic Sci pmid:22675588
Sikorski J et al. Complete genome sequence of Segniliparus rotundus type strain (CDC 1076). 2010 Stand Genomic Sci pmid:21304703
Lotfy HM and Abdel-Monem Hagazy M Comparative study of novel spectrophotometric methods manipulating ratio spectra: an application on pharmaceutical ternary mixture of omeprazole, tinidazole and clarithromycin. 2012 Spectrochim Acta A Mol Biomol Spectrosc pmid:22683662
Ahmed S and Atia NN Simultaneous determination of triple therapy for Helicobacter pylori in human plasma by reversed phase chromatography with online wavelength switching. 2015 Spectrochim Acta A Mol Biomol Spectrosc pmid:25459696
Sadeghifard N et al. Survey in Iran of clarithromycin resistance in Helicobacter pylori isolates by PCR-RFLP. 2013 Southeast Asian J. Trop. Med. Public Health pmid:23682442
Kumala W and Rani A Patterns of Helicobacter pylori isolate resistance to fluoroquinolones, amoxicillin, clarithromycin and metronidazoles. 2006 Southeast Asian J. Trop. Med. Public Health pmid:17333742
Iamsawat S et al. Multiplex PCR for detection of clarithromycin resistance and simultaneous species identification of Mycobacterium avium complex. 2010 Southeast Asian J. Trop. Med. Public Health pmid:20578547
Waites K et al. In vitro activities of oral antimicrobial agents against penicillin-resistant Streptococcus pneumoniae: implications for outpatient treatment. 1997 South. Med. J. pmid:9191739
Krishna M and Lalmuanpuii J Helicobacter pylori treatment. 2005 South. Med. J. pmid:16351026
Gurbuz AK et al. Effect of N-acetyl cysteine on Helicobacter pylori. 2005 South. Med. J. pmid:16351030
Kanbay M et al. Hyponatremia due to an additive effect of carbamazepine and clarithromycin. 2007 South. Med. J. pmid:17330699
Ermis F et al. Second-line levofloxacin-based triple therapy's efficiency for Helicobacter pylori eradication in patients with peptic ulcer. 2011 South. Med. J. pmid:21886067
Bégué RE et al. Effect of Helicobacter pylori eradication in the glycemia of children with type 1 diabetes: a preliminary study. 2002 South. Med. J. pmid:12190218
Nadir I et al. Comparison of two different treatment protocols in Helicobacter pylori eradication. 2011 South. Med. J. pmid:21206418
Knower MT et al. Clarithromycin for safe and cost-effective reduction of cyclosporine doses in lung allograft recipients. 2000 South. Med. J. pmid:11095559
Asnis DS et al. Mycobacterium avium-intracellulare complex pneumonia in a non-HIV-infected individual: an increasingly recognized disease. 1996 South. Med. J. pmid:8638183
Demir M et al. Clarithromycin resistance and efficacy of clarithromycin-containing triple eradication therapy for Helicobacter pylori infection in type 2 diabetes mellitus patients. 2009 South. Med. J. pmid:19864973
Cheng VC et al. Two probable cases of serious drug interaction between clarithromycin and colchicine. 2005 South. Med. J. pmid:16144178
Randhawa K et al. Nine-year progression of untreated pulmonary Mycobacterium szulgai infection. 2010 South. Med. J. pmid:20622732
Singh V et al. Vesicular palmoplantar pityriasis rosea. 2012 Mar-Apr Skinmed pmid:22545332
Bernstein JM and Bacheller CD It's on the tip of my tongue. Skinmed pmid:16687984
Alberts JH and Boyd AS Nocardia otitidiscaviarum: an unusual Nocardia species causing a primary lymphocutaneous infectious process in a mildly immunosuppressed patient. 2002 Sep-Oct Skinmed pmid:14673241
Ling KL et al. Efficacy of a nitroimidazole containing tripletherapy regime in Singapore. 2001 Singapore Med J pmid:11599627
Luman W et al. One week triple therapy for Helicobacter pylori associated duodenal ulcer disease. 1999 Singapore Med J pmid:10709423
Zainal Muttakin AR and Tan AM Mycobacterium fortuitum catheter-related sepsis in acute leukaemia. 2006 Singapore Med J pmid:16752025
Chew CA et al. The diagnosis and management of H. pylori infection in Singapore. 2017 Singapore Med J pmid:28536725
Khor CJ et al. Recurrence of Helicobacter pylori infection and duodenal ulcer relapse, following successful eradication in an urban east Asian population. 2000 Singapore Med J pmid:11256345
Goh IX et al. Cytochrome P450 drug interactions with statin therapy. 2013 Singapore Med J pmid:23546024
Fock KM et al. A randomised trial of amoxycillin versus clarithromycin in combination with omeprazole for eradication of Helicobacter pylori infection in Singapore. 2000 Singapore Med J pmid:11281438
Mak SK et al. A retrospective study on efficacy of proton-pump inhibitor-based triple therapy for eradication of Helicobacter pylori in patients with chronic renal failure. 2003 Singapore Med J pmid:14503780
Prime K and French P Neuropsychiatric reaction induced by clarithromycin in a patient on highly active antiretroviral therapy (HAART). 2001 Sex Transm Infect pmid:11463936
Colebunders R and Florence E Neuropsychiatric reaction induced by clarithromycin. 2002 Sex Transm Infect pmid:11872875
Zheng H et al. Association of the in vitro susceptibility of clinical isolates of chlamydia trachomatis with serovar and duration of antibiotic exposure. 2015 Sex Transm Dis pmid:25668641
Abu-Khalaf N et al. The Taste of Commercially Available Clarithromycin Oral Pharmaceutical Suspensions in the Palestinian Market: Electronic Tongue and In Vivo Evaluation. 2018 Sensors (Basel) pmid:29401675
Kobayashi Y et al. Advanced taste sensors based on artificial lipids with global selectivity to basic taste qualities and high correlation to sensory scores. 2010 Sensors (Basel) pmid:22319306
Dimopoulos MA et al. Treatment of Waldenstrom's macroglobulinemia with single-agent thalidomide or with the combination of clarithromycin, thalidomide and dexamethasone. 2003 Semin. Oncol. pmid:12720150
Coleman M et al. Treatment of Waldenstrom's macroglobulinemia with clarithromycin, low-dose thalidomide, and dexamethasone. 2003 Semin. Oncol. pmid:12720151
Hoffman JS Pharmacological therapy of Helicobacter pylori infection. 1997 Semin. Gastrointest. Dis. pmid:9232728