clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Tenosynovitis D013717 3 associated lipids
Splenic Diseases D013158 5 associated lipids
Hernia, Hiatal D006551 3 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Leprosy, Lepromatous D015440 2 associated lipids
Gastritis, Hypertrophic D005758 1 associated lipids
Hypoproteinemia D007019 1 associated lipids
Cutaneous Fistula D017577 1 associated lipids
Tuberculosis, Ocular D014392 1 associated lipids
Euthyroid Sick Syndromes D005067 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Furusyo N et al. Rapidly growing primary gastric B-cell lymphoma after eradication of Helicobacter pylori. 1999 Intern. Med. pmid:10526942
Chérin P et al. Macrophagic myofasciitis: improvement with antibiotic therapy. 1999 J. Rheumatol. pmid:10529163
Moola S et al. A multicenter study of grepafloxacin and clarithromycin in the treatment of patients with community-acquired pneumonia. 1999 Chest pmid:10531162
Gonzalez Cueto D et al. [Gastric solitary plasmacytoma associated with +Helicobacter pylori infection]. 1999 Acta Gastroenterol. Latinoam. pmid:10533659
Saito H et al. [Chemoprophylaxis against Mycobacterium avium complex infection induced in mice]. 1999 Kekkaku pmid:10535281
Gisbert JP et al. Seven-day 'rescue' therapy after Helicobacter pylori treatment failure: omeprazole, bismuth, tetracycline and metronidazole vs. ranitidine bismuth citrate, tetracycline and metronidazole. 1999 Aliment. Pharmacol. Ther. pmid:10540045
Hammett DC and Evans MF Functional (non-ulcer) dyspepsia and Helicobacter pylori infection. To treat or not to treat? 1999 Can Fam Physician pmid:10540692
Sassa K et al. Differential modulatory effects of clarithromycin on the production of cytokines by a tumor. 1999 Antimicrob. Agents Chemother. pmid:10543765
Goldstein EJ et al. Activities of telithromycin (HMR 3647, RU 66647) compared to those of erythromycin, azithromycin, clarithromycin, roxithromycin, and other antimicrobial agents against unusual anaerobes. 1999 Antimicrob. Agents Chemother. pmid:10543769
Unal M et al. Ocular toxicity of intravitreal clarithromycin. 1999 Retina (Philadelphia, Pa.) pmid:10546942
Woo PC et al. Antibiotics modulate vaccine-induced humoral immune response. 1999 Clin. Diagn. Lab. Immunol. pmid:10548572
Adamsson I et al. Comparative effects of omeprazole, amoxycillin plus metronidazole versus omeprazole, clarithromycin plus metronidazole on the oral, gastric and intestinal microflora in Helicobacter pylori-infected patients. 1999 J. Antimicrob. Chemother. pmid:10552979
Cirioni O et al. In-vitro activity of rifabutin and albendazole singly and in combination with other clinically used antimicrobial agents against Pneumocystis carinii. 1999 J. Antimicrob. Chemother. pmid:10552982
Yoshida Y et al. Synthesis and anti-Helicobacter pylori activity of FR182024, a new cephem derivative. 1999 Bioorg. Med. Chem. Lett. pmid:10560737
Valencia IC et al. Disseminated cutaneous Mycobacterium chelonae infection after injection of bovine embryonic cells. 1999 Int. J. Dermatol. pmid:10561050
Martín de Argila C and Boixeda D [A ration proposal for the eradicating treatment of Helicobacter pylori infection]. 1999 Med Clin (Barc) pmid:10562929
Adeyemi EO et al. The outcome of a 2-week treatment of Helicobacter pylori-positive duodenal ulcer with omeprazole-based antibiotic regimen in a region with high metronidazole resistance rate. 1999 Eur J Gastroenterol Hepatol pmid:10563537
Sharma VK et al. A survey of gastroenterologists' perceptions and practices related to Helicobacter pylori infection. 1999 Am. J. Gastroenterol. pmid:10566709
Fattorini L et al. Activities of eighteen antimicrobial regimens against Mycobacterium avium infection in beige mice. 1999 Microb. Drug Resist. pmid:10566874
Lamouliatte H et al. Double vs. single dose of pantoprazole in combination with clarithromycin and amoxycillin for 7 days, in eradication of Helicobacter pylori in patients with non-ulcer dyspepsia. 1999 Aliment. Pharmacol. Ther. pmid:10571611