clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Tenosynovitis D013717 3 associated lipids
Splenic Diseases D013158 5 associated lipids
Hernia, Hiatal D006551 3 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Leprosy, Lepromatous D015440 2 associated lipids
Gastritis, Hypertrophic D005758 1 associated lipids
Hypoproteinemia D007019 1 associated lipids
Cutaneous Fistula D017577 1 associated lipids
Tuberculosis, Ocular D014392 1 associated lipids
Euthyroid Sick Syndromes D005067 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Maurin M and Raoult D In vitro susceptibilities of spotted fever group rickettsiae and Coxiella burnetti to clarithromycin. 1993 Antimicrob. Agents Chemother. pmid:8109928
Scaglione F et al. Immunostimulation by clarithromycin in healthy volunteers and chronic bronchitis patients. 1993 J Chemother pmid:8229150
Andrews J and Wise R Disk susceptibility testing for clarithromycin. 1993 Eur. J. Clin. Microbiol. Infect. Dis. pmid:8187799
Calhoun KH and Hokanson JA Multicenter comparison of clarithromycin and amoxicillin in the treatment of acute maxillary sinusitis. 1993 Arch Fam Med pmid:8111512
Saint-Marc T et al. [Mycobacterium avium intracellulare infections. Treatment with a clarithromycin-clofazimine combination. 18 cases]. 1993 Presse Med pmid:8121903
Akiyama H et al. Interaction of Staphylococcus aureus cells and silk threads in vitro and in mouse skin. 1993 J. Dermatol. Sci. pmid:8136322
Dautzenberg B et al. Clarithromycin and other antimicrobial agents in the treatment of disseminated Mycobacterium avium infections in patients with acquired immunodeficiency syndrome. 1993 Arch. Intern. Med. pmid:8427539
Clinical Perspectives on Clarithromycin in Pediatric Infections. Symposium proceedings. February 19-20, 1993. 1993 Pediatr. Infect. Dis. J. pmid:7905199
Guay DR and Craft JC Overview of the pharmacology of clarithromycin suspension in children and a comparison with that in adults. 1993 Pediatr. Infect. Dis. J. pmid:8295810
Hebert AA et al. Comparative safety and efficacy of clarithromycin and cefadroxil suspensions in the treatment of mild to moderate skin and skin structure infections in children. 1993 Pediatr. Infect. Dis. J. pmid:8295811
Pukander JS et al. Clarithromycin vs. amoxicillin suspensions in the treatment of pediatric patients with acute otitis media. 1993 Pediatr. Infect. Dis. J. pmid:8295812
McCarty JM et al. Comparative safety and efficacy of clarithromycin and amoxicillin/clavulanate in the treatment of acute otitis media in children. 1993 Pediatr. Infect. Dis. J. pmid:8295813
Gooch WM et al. Clarithromycin and cefaclor suspensions in the treatment of acute otitis media in children. 1993 Pediatr. Infect. Dis. J. pmid:8295814
Still JG et al. Comparison of clarithromycin and penicillin VK suspensions in the treatment of children with streptococcal pharyngitis and review of currently available alternative antibiotic therapies. 1993 Pediatr. Infect. Dis. J. pmid:8295815
Craft JC and Siepman N Overview of the safety profile of clarithromycin suspension in pediatric patients. 1993 Pediatr. Infect. Dis. J. pmid:8295816
Klein JO Clarithromycin: where do we go from here? 1993 Pediatr. Infect. Dis. J. pmid:8295817
Hardy DJ Extent and spectrum of the antimicrobial activity of clarithromycin. 1993 Pediatr. Infect. Dis. J. pmid:8295818
de Vega T et al. Clarithromycin-induced leukocytoclastic vasculitis. 1993 Eur. J. Clin. Microbiol. Infect. Dis. pmid:8404922
Chu S et al. Single- and multiple-dose pharmacokinetics of clarithromycin, a new macrolide antimicrobial. 1993 J Clin Pharmacol pmid:8408732
Barradell LB et al. Clarithromycin. A review of its pharmacological properties and therapeutic use in Mycobacterium avium-intracellulare complex infection in patients with acquired immune deficiency syndrome. 1993 Drugs pmid:7691518