| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tenosynovitis | D013717 | 3 associated lipids |
| Splenic Diseases | D013158 | 5 associated lipids |
| Hernia, Hiatal | D006551 | 3 associated lipids |
| Chlamydial Pneumonia | D061387 | 2 associated lipids |
| Leprosy, Lepromatous | D015440 | 2 associated lipids |
| Gastritis, Hypertrophic | D005758 | 1 associated lipids |
| Hypoproteinemia | D007019 | 1 associated lipids |
| Cutaneous Fistula | D017577 | 1 associated lipids |
| Tuberculosis, Ocular | D014392 | 1 associated lipids |
| Euthyroid Sick Syndromes | D005067 | 1 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kruppa A et al. | Immediate reaction to roxithromycin and prick test cross-sensitization to erythromycin and clarithromycin. | 1998 | Dermatology (Basel) | pmid:9621142 |
| Ishii K et al. | Comparative study of pharmacokinetic parameters between clarithromycin and erythromycin stearate in relation to their physicochemical properties. | 1998 | Drug Dev Ind Pharm | pmid:15605442 |
| Rosário M et al. | [Profile of the resistance to macrolides and imidazoles of Helicobacter pylori in a sample of the Portuguese population]. | 1998 | Acta Med Port | pmid:10192979 |
| Highleyman L | FDA issues Hismanal warning. Food and Drug Administration. | 1998 | BETA | pmid:11365263 |
| Finkenbine RD and Frye MD | Case of psychosis due to prednisone-clarithromycin interaction. | 1998 | Gen Hosp Psychiatry | pmid:9788033 |
| Borody TJ | Helicobacter pylori eradication failure--'salvage' therapies needed. | 1998 | Ital J Gastroenterol Hepatol | pmid:9789131 |
| Coudron PE and Stratton CW | The bactericidal activity of clarithromycin versus ampicillin alone and in combination with omeprazole and/or bismuth against clarithromycin-susceptible and clarithromycin-resistant strains of Helicobacter pylori. | 1998 | Diagn. Microbiol. Infect. Dis. | pmid:9791756 |
| Niang M et al. | [Painful nodular lesions]. | 1998 | Rev Med Interne | pmid:9793156 |
| Saika T et al. | [A mechanism of clarithromycin resistance in Helicobacter pylori]. | 1998 | Kansenshogaku Zasshi | pmid:9796191 |
| Abouesh A and Hobbs WR | Clarithromycin-induced mania. | 1998 | Am J Psychiatry | pmid:9812131 |
| Shimoyama T et al. | Healing of cimetidine-resistant Ménétrier's disease by eradication of Helicobacter pylori infection. | 1998 | J. Clin. Gastroenterol. | pmid:9855268 |
| Siu LK et al. | Evaluation of a selective transport medium for gastric biopsy specimens to be cultured for Helicobacter pylori. | 1998 | J. Clin. Microbiol. | pmid:9738066 |
| Sevin E et al. | Co-detection of Helicobacter pylori and of its resistance to clarithromycin by PCR. | 1998 | FEMS Microbiol. Lett. | pmid:9742711 |
| Hiratsuka T et al. | [Severe bronchorrhea accompanying alveolar cell carcinoma: treatment with clarithromycin and inhaled beclomethasone]. | 1998 | Nihon Kokyuki Gakkai Zasshi | pmid:9742869 |
| Hynes B | Contact granulomas. | 1998 | J Otolaryngol | pmid:9800633 |
| Fischer BP et al. | [Tsutsugamushi fever. Rare rickettsiosis after a stay in the Philippines]. | 1998 | Dtsch. Med. Wochenschr. | pmid:9615696 |
| Torresani C | Clarithromycin: a new perspective in rosacea treatment. | 1998 | Int. J. Dermatol. | pmid:9620480 |
| Lygren I et al. | [Treatment of Helicobacter pylori infection]. | 1998 | Tidsskr. Nor. Laegeforen. | pmid:9889634 |
| Einarson A et al. | A prospective controlled multicentre study of clarithromycin in pregnancy. | 1998 | Am J Perinatol | pmid:9890248 |
| Tsuneoka H et al. | [Sensitivity of Helicobacter pylori to amoxicillin and clarythromycin with special reference to eradication therapy]. | 1998 | Kansenshogaku Zasshi | pmid:9621560 |
| Amsden GW et al. | Oral cimetidine prolongs clarithromycin absorption. | 1998 | Antimicrob. Agents Chemother. | pmid:9660986 |
| Spinzi GC et al. | Comparison of omeprazole and lansoprazole in short-term triple therapy for Helicobacter pylori infection. | 1998 | Aliment. Pharmacol. Ther. | pmid:9663722 |
| Bazzoli F et al. | Evaluation of short-term low-dose triple therapy for the eradication of Helicobacter pylori by factorial design in a randomized, double-blind, controlled study. | 1998 | Aliment. Pharmacol. Ther. | pmid:9663723 |
| Pozzato P et al. | Ranitidine bismuth citrate plus clarithromycin 7-day regimen is effective in eradicating Helicobacter pylori in patients with duodenal ulcer. | 1998 | Aliment. Pharmacol. Ther. | pmid:9663724 |
| Hahn DL et al. | Evidence for Chlamydia pneumoniae infection in steroid-dependent asthma. | 1998 | Ann. Allergy Asthma Immunol. | pmid:9475566 |
| Butt AA | Cervical adenitis due to Mycobacterium fortuitum in patients with acquired immunodeficiency syndrome. | 1998 | Am. J. Med. Sci. | pmid:9427575 |
| Sonnenberg A et al. | Cost savings in duodenal ulcer therapy through Helicobacter pylori eradication compared with conventional therapies: results of a randomized, double-blind, multicenter trial. Gastrointestinal Utilization Trial Study Group. | 1998 | Arch. Intern. Med. | pmid:9570170 |
| Dal Bo' N et al. | Low dose of clarithromycin in triple therapy for the eradication of Helicobacter pylori: one or two weeks? | 1998 | J. Gastroenterol. Hepatol. | pmid:9570242 |
| O'Connor HJ et al. | Lansoprazole triple therapy for Helicobacter pylori--is 5 days enough? | 1998 | Aliment. Pharmacol. Ther. | pmid:9570262 |
| Scott BB | Bismuth-containing single-antibiotic 1-week triple therapy for Helicobacter pylori eradication. | 1998 | Aliment. Pharmacol. Ther. | pmid:9570263 |
| Jarboe E et al. | Evaluation of a disk diffusion method for determining susceptibility of Mycobacterium avium complex to clarithromycin. | 1998 | Diagn. Microbiol. Infect. Dis. | pmid:9572027 |
| Borody TJ et al. | Eradication therapies for Helicobacter pylori. | 1998 | J. Gastroenterol. | pmid:9840019 |
| Moayyedi P et al. | Relevance of antibiotic sensitivities in predicting failure of omeprazole, clarithromycin, and tinidazole to eradicate Helicobacter pylori. | 1998 | J. Gastroenterol. | pmid:9840021 |
| Ohkusa T et al. | Disappearance of hyperplastic polyps in the stomach after eradication of Helicobacter pylori. A randomized, clinical trial. | 1998 | Ann. Intern. Med. | pmid:9841603 |
| Kato S et al. | Safety and efficacy of one-week triple therapy for eradicating Helicobacter pylori in children. | 1998 | Helicobacter | pmid:9844069 |
| Gisbert JP et al. | [Omeprazole plus 2 antibiotics for the eradication of H. pylori, are 5 days of treatment sufficient?]. | 1998 | Rev Clin Esp | pmid:9844453 |
| Gisbert JP et al. | [Role of pantoprazole in the eradicating treatment of Helicobacter pylori]. | 1998 | Rev Clin Esp | pmid:9844458 |
| Gudjonsson H et al. | High Helicobacter pylori eradication rate with a 1-week regimen containing ranitidine bismuth citrate. | 1998 | Aliment. Pharmacol. Ther. | pmid:9845401 |
| Isono K et al. | [Effects of macrolide antibiotics on neutrophil infiltration into the airway mucosa and ICAM-1 expression]. | 1998 | Jpn J Antibiot | pmid:9597480 |
| Enomoto F et al. | [Changes in adhesion molecule expressions in neutrophils caused by new macrolide administration]. | 1998 | Jpn J Antibiot | pmid:9597482 |
| Ieshiro R et al. | [Effect of clarithromycin in extending the life expectancy of patients with non-small-cell lung cancer--the second report]. | 1998 | Jpn J Antibiot | pmid:9597484 |
| Sakamoto M et al. | [Efficacy of clarithromycin (CAM) in patients with inoperable non-small-cell lung cancer]. | 1998 | Jpn J Antibiot | pmid:9597485 |
| Teramoto S et al. | [Effect of clarithromycin administration on interferon-gamma and interleukin 12 mRNA expression in the tumor tissue of non-small-cell lung cancer]. | 1998 | Jpn J Antibiot | pmid:9597486 |
| Ueta K et al. | [Evaluation of BRM (biological response modifier) action of clarithromycin (CAM)--effect on cytokine expression in a mouse lung cancer model]. | 1998 | Jpn J Antibiot | pmid:9597487 |
| Kokubo Y et al. | [Effect of clarithromycin on experimental pulmonary metastasis]. | 1998 | Jpn J Antibiot | pmid:9597488 |
| Yano S et al. | [Significance of therapeutic efficacy of clarithromycin in a model for human lung cancer metastasis and a mouse tumor system]. | 1998 | Jpn J Antibiot | pmid:9597491 |
| Sasa K et al. | [Antineoplastic therapeutic effect of clarithromycin in rats]. | 1998 | Jpn J Antibiot | pmid:9597492 |
| Schwartz H et al. | Triple versus dual therapy for eradicating Helicobacter pylori and preventing ulcer recurrence: a randomized, double-blind, multicenter study of lansoprazole, clarithromycin, and/or amoxicillin in different dosing regimens. | 1998 | Am. J. Gastroenterol. | pmid:9576452 |
| Felmingham D et al. | Antimicrobial susceptibility of community-acquired lower respiratory tract bacterial pathogens isolated in the UK during the 1995-1996 cold season. | 1998 | J. Antimicrob. Chemother. | pmid:9578171 |
| Tatsis G et al. | Efficacy and tolerance of roxithromycin versus clarithromycin in the treatment of lower respiratory tract infections. | 1998 | J. Antimicrob. Chemother. | pmid:9579716 |
| Perng CL et al. | One-week triple therapy with lansoprazole, clarithromycin, and metronidazole to cure Helicobacter pylori infection in peptic ulcer disease in Korea. | 1998 | Dig. Dis. Sci. | pmid:9539638 |
| Scheen AJ | [Drug clinics. The drug of the month. Ranitidine bismuth citrate (Pylorid)]. | 1998 | Rev Med Liege | pmid:9555183 |
| Cheng KL et al. | Effect of grapefruit juice on clarithromycin pharmacokinetics. | 1998 | Antimicrob. Agents Chemother. | pmid:9559810 |
| Ramon PM et al. | [Uveitis, arthralgia and pseudo-jaundice in a HIV seronegative patient due to rifabutin]. | 1998 | Rev Mal Respir | pmid:9608993 |
| Lilley LL and Guanci R | A dangerous combination. | 1998 | Am J Nurs | pmid:9612423 |
| Sheu BS et al. | One-week proton pump inhibitor-based triple therapy eradicates residual Helicobacter pylori after failed dual therapy. | 1998 | J. Formos. Med. Assoc. | pmid:9585678 |
| Hasegawa M et al. | [In vitro activities of faropenem against clarithromycin resistance Helicobacter pylori isolates]. | 1998 | Kansenshogaku Zasshi | pmid:9585692 |
| Carr RA et al. | Steady-state pharmacokinetics and electrocardiographic pharmacodynamics of clarithromycin and loratadine after individual or concomitant administration. | 1998 | Antimicrob. Agents Chemother. | pmid:9593146 |
| Lacy MK et al. | Comparison of bactericidal activity after multidose administration of clarithromycin, azithromycin, and ceruroxime axetil against Streptococcus pneumoniae. | 1998 | Int. J. Antimicrob. Agents | pmid:9916901 |
| Fera MT et al. | Bactericidal activity of lansoprazole and three macrolides against Helicobacter pylori strains tested by the time-kill kinetic method. | 1998 | Int. J. Antimicrob. Agents | pmid:9916902 |
| Holmberg SD et al. | Possible effectiveness of clarithromycin and rifabutin for cryptosporidiosis chemoprophylaxis in HIV disease. HIV Outpatient Study (HOPS) Investigators. | 1998 | JAMA | pmid:9459473 |
| Cecchi R and Torelli E | Schönlein-Henoch purpura in association with duodenal ulcer and gastric Helicobacter pylori infection. | 1998 | J. Dermatol. | pmid:9714985 |
| Dore MP et al. | Demonstration of unexpected antibiotic resistance of genotypically identical Helicobacter pylori isolates. | 1998 | Clin. Infect. Dis. | pmid:9675458 |
| Dunne EF et al. | Streptomyces pneumonia in a patient with human immunodeficiency virus infection: case report and review of the literature on invasive streptomyces infections. | 1998 | Clin. Infect. Dis. | pmid:9675460 |
| Wiedermann BL | Macrolides: clarithromycin and azithromycin. | 1998 | Pediatr Rev | pmid:9654947 |
| Tanahashi T et al. | Analysis of the 13C-urea breath test for detection of Helicobacter pylori infection based on the kinetics of delta-13CO2 using laser spectroscopy. | 1998 | J. Gastroenterol. Hepatol. | pmid:9715426 |
| Hashimoto Y | [Eradication therapies for Helicobacter pylori]. | 1998 | Kansenshogaku Zasshi | pmid:9695480 |
| Wakasugi H et al. | Effect of clarithromycin on renal excretion of digoxin: interaction with P-glycoprotein. | 1998 | Clin. Pharmacol. Ther. | pmid:9695727 |
| Hsieh PF et al. | Molecular mechanisms of clarithromycin resistance in Helicobacter pylori. | 1998 | J. Formos. Med. Assoc. | pmid:9700240 |
| Ellenrieder V et al. | Influence of clarithromycin dosage on pantoprazole combined triple therapy for eradication of Helicobacter pylori. | 1998 | Aliment. Pharmacol. Ther. | pmid:9701524 |
| Burman WJ et al. | AIDS-related Mycobacterium kansasii infection with initial resistance to clarithromycin. | 1998 | Diagn. Microbiol. Infect. Dis. | pmid:9635911 |
| Nordt SP et al. | Clarithromycin induced digoxin toxicity. | 1998 | J Accid Emerg Med | pmid:9639187 |
| Dehesa M et al. | [Comparison of 2 schedules based on pantoprazole for eradication of Helicobacter pylori in patients with active duodenal ulcer]. | 1998 Apr-Jun | Rev Gastroenterol Mex | pmid:10068730 |
| Fennerty MB et al. | A comparison of 10 and 14 days of lansoprazole triple therapy for eradication of Helicobacter pylori. | 1998 Aug 10-24 | Arch. Intern. Med. | pmid:9701099 |
| Mikamo H et al. | Effects of long-term/low-dose clarithromycin on neutrophil count and interleukin-8 level in pyometra. | 1998 Jan-Feb | Chemotherapy | pmid:9444409 |
| Ziering W and McElvaine P | Randomized comparison of once-daily ceftibuten and twice-daily clarithromycin in the treatment of acute exacerbation of chronic bronchitis. | 1998 Jan-Feb | Infection | pmid:9505188 |
| Langan C et al. | Short-course cefuroxime axetil therapy in the treatment of acute exacerbations of chronic bronchitis. | 1998 Jul-Aug | Int. J. Clin. Pract. | pmid:9796558 |
| Habu Y et al. | Triple therapy with omeprazole, amoxicillin and clarithromycin is effective against Helicobacter pylori infection in gastric ulcer patients as well as in duodenal ulcer patients. Results of a randomized controlled trial in Japan. | 1998 Jul-Aug | Digestion | pmid:9693202 |
| Shafran SD | Prevention and treatment of disseminated Mycobacterium avium complex infection in human immunodeficiency virus-infected individuals. | 1998 Jul-Sep | Int. J. Infect. Dis. | pmid:9831675 |
| Venuta A et al. | Azithromycin compared with clarithromycin for the treatment of streptococcal pharyngitis in children. | 1998 Jun-Jul | J. Int. Med. Res. | pmid:9718470 |
| Fernández Bermejo M and GarcÃa Grávalos R | [Ebrotidine in the eradicating treatment of H. pylori]. | 1998 Jun-Jul | Gastroenterol Hepatol | pmid:9711019 |
| Oberg KC | Delayed elevation of international normalized ratio with concurrent clarithromycin and warfarin therapy. | 1998 Mar-Apr | Pharmacotherapy | pmid:9545160 |
| Vakil N | Treatment of H. pylori infection: the reality. | 1998 Mar-Apr | Yale J Biol Med | pmid:10378357 |
| Miehlke S et al. | Comparison of omeprazole, metronidazole and clarithromycin with omeprazole/amoxicillin dual-therapy for the cure of Helicobacter pylori infection. | 1998 Nov-Dec | Digestion | pmid:9813387 |
| Adelglass J et al. | A multicenter, investigator-blinded, randomized comparison of oral levofloxacin and oral clarithromycin in the treatment of acute bacterial sinusitis. | 1998 Nov-Dec | Pharmacotherapy | pmid:9855324 |
| Tohnai A et al. | Clarithromycin suppresses proliferation of rat nasal epithelium exposed to endotoxin. | 1998 Nov-Dec | Am J Rhinol | pmid:9883303 |
| Mermelstein HT | Clarithromycin-induced delirium in a general hospital. | 1998 Nov-Dec | Psychosomatics | pmid:9819955 |
| Anzueto A et al. | Etiology, susceptibility, and treatment of acute bacterial exacerbations of complicated chronic bronchitis in the primary care setting: ciprofloxacin 750 mg b.i.d. versus clarithromycin 500 mg b.i.d. Bronchitis Study Group. | 1998 Sep-Oct | Clin Ther | pmid:9829441 |
| GarcÃa-Romero E et al. | [Treatment with omeprazole, clarithromycin and amoxicillin over 6 days in patients with Helicobacter pylori-infected duodenal ulcer]. | 1999 | Gastroenterol Hepatol | pmid:10089703 |
| Giacometti A et al. | In vitro anticryptosporidial activity of ranalexin alone and in combination with other peptides and with hydrophobic antibiotics. | 1999 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:10614961 |
| Suleymanlar I et al. | Response to triple treatment with omeprazole, amoxicillin, and clarithromycin for Helicobacter pylori infections in continuous ambulatory peritoneal dialysis patients. | 1999 | Adv Perit Dial | pmid:10682076 |
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| Sato K et al. | [MICs and MBCs of levofloxacin, clarithromycin, and KRM-1648 for Mycobacterium tuberculosis and M. avium complex residing in MONO-MAC-6 human macrophage-like cell and A-549 human type II alveolar epithelial cell lines]. | 1999 | Kekkaku | pmid:10481412 |
| Blackington E | The gastric demon. An update on Helicobacter pylori infection. | 1999 | Adv Nurse Pract | pmid:10745720 |
| Owen RJ et al. | Effect of clarithromycin and omeprazole therapy on the diversity and stability of genotypes of Helicobacter pylori from duodenal ulcer patients. | 1999 | Microb. Drug Resist. | pmid:10432275 |
| Woods GL et al. | Multisite reproducibility of results obtained by the broth microdilution method for susceptibility testing of Mycobacterium abscessus, Mycobacterium chelonae, and Mycobacterium fortuitum. | 1999 | J. Clin. Microbiol. | pmid:10325306 |
| Iida H et al. | Hypoglycemia induced by interaction between clarithromycin and disopyramide. | 1999 | Jpn Heart J | pmid:10370402 |
| Gisbert JP | [Lansoprazole: a review of its role in Helicobacter pylori eradication therapy]. | 1999 | Rev Esp Enferm Dig | pmid:10231305 |
| Realdi G et al. | Pretreatment antibiotic resistance in Helicobacter pylori infection: results of three randomized controlled studies. | 1999 | Helicobacter | pmid:10382124 |
| Ku YY et al. | Synthesis and antibacterial activities of novel 12-O-methylerythromycin A derivatives. | 1999 | J. Antibiot. | pmid:10604761 |