| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tenosynovitis | D013717 | 3 associated lipids |
| Splenic Diseases | D013158 | 5 associated lipids |
| Hernia, Hiatal | D006551 | 3 associated lipids |
| Chlamydial Pneumonia | D061387 | 2 associated lipids |
| Leprosy, Lepromatous | D015440 | 2 associated lipids |
| Gastritis, Hypertrophic | D005758 | 1 associated lipids |
| Hypoproteinemia | D007019 | 1 associated lipids |
| Cutaneous Fistula | D017577 | 1 associated lipids |
| Tuberculosis, Ocular | D014392 | 1 associated lipids |
| Euthyroid Sick Syndromes | D005067 | 1 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| FDA approves Biaxin for MAC prophylaxis. Food and Drug Administration. | 1995 | J Int Assoc Physicians AIDS Care | pmid:11363096 | |
| Jaup BH and Norrby A | Low dose, short-term triple therapy for cure of Helicobacter pylori infection and healing of peptic ulcers. | 1995 | Am. J. Gastroenterol. | pmid:7771426 |
| Musher DM | Clarithromycin therapy for Mycobacterium avium complex bacteremia. | 1995 | Ann. Intern. Med. | pmid:7778830 |
| van der Meer JT and Danner SA | Clarithromycin therapy for Mycobacterium avium complex bacteremia. | 1995 | Ann. Intern. Med. | pmid:7778831 |
| Burette A and Glupczynski Y | Helicobacter pylori: the place of the new macrolides in the eradication of the bacteria in peptic ulcer disease. | 1995 | Infection | pmid:7782116 |
| Savarino V et al. | Helicobacter pylori eradication and reinfection. | 1995 | Lancet | pmid:7783564 |
| Comley JC and Sterling AM | Effect of atovaquone and atovaquone drug combinations on prophylaxis of Pneumocystis carinii pneumonia in SCID mice. | 1995 | Antimicrob. Agents Chemother. | pmid:7785975 |
| Odenholt-Tornqvist I et al. | Postantibiotic effects and postantibiotic sub-MIC effects of roxithromycin, clarithromycin, and azithromycin on respiratory tract pathogens. | 1995 | Antimicrob. Agents Chemother. | pmid:7695310 |
| Struillou L et al. | Activities of roxithromycin against Mycobacterium avium infections in human macrophages and C57BL/6 mice. | 1995 | Antimicrob. Agents Chemother. | pmid:7785988 |
| Fong IW et al. | Clarithromycin versus cefaclor in lower respiratory tract infections. The Canadian Bronchitis Study Group. | 1995 | Clin Invest Med | pmid:7788958 |
| Goddard A and Logan R | One-week low-dose triple therapy: new standards for Helicobacter pylori treatment. | 1995 | Eur J Gastroenterol Hepatol | pmid:7866804 |
| Weits J and Sprenger HG | [Surgical treatment of lymphadenitis caused by non-tuberculous mycobacteria in children]. | 1995 | Ned Tijdschr Geneeskd | pmid:8524431 |
| RamÃrez Ramos A | [Treatment of Helicobacter pylori infection: current status]. | 1995 | Rev Gastroenterol Peru | pmid:8520021 |
| Lee D et al. | Localized Mycobacterium avium-intracellulare mastitis in an immunocompetent woman with silicone breast implants. | 1995 | Plast. Reconstr. Surg. | pmid:7809228 |
| Midoneck SR and Etingin OR | Clarithromycin-related toxic effects of digoxin. | 1995 | N. Engl. J. Med. | pmid:7477159 |
| Forslund T et al. | Disseminated cutaneous infection due to Mycobacterium chelonae in a patient with rheumatoid arthritis, amyloidosis, and renal failure. | 1995 | Nephrol. Dial. Transplant. | pmid:7478131 |
| Cavalieri SJ et al. | Synergistic activities of clarithromycin and antituberculous drugs against multidrug-resistant Mycobacterium tuberculosis. | 1995 | Antimicrob. Agents Chemother. | pmid:7492101 |
| Citron DM et al. | Activity of ampicillin/sulbactam, ticarcillin/clavulanate, clarithromycin, and eleven other antimicrobial agents against anaerobic bacteria isolated from infections in children. | 1995 | Clin. Infect. Dis. | pmid:7548597 |
| Ishii K et al. | A new pharmacokinetic model including in vivo dissolution and gastrointestinal transit parameters. | 1995 | Biol. Pharm. Bull. | pmid:7550125 |
| Harris AW et al. | Eradication of Helicobacter pylori with lansoprazole and clarithromycin. | 1995 | Aliment. Pharmacol. Ther. | pmid:7605863 |
| Katelaris PH et al. | A randomized prospective comparison of clarithromycin versus amoxycillin in combination with omeprazole for eradication of Helicobacter pylori. | 1995 | Aliment. Pharmacol. Ther. | pmid:7605864 |
| Yousfi MM et al. | Metronidazole, omeprazole and clarithromycin: an effective combination therapy for Helicobacter pylori infection. | 1995 | Aliment. Pharmacol. Ther. | pmid:7605865 |
| Chevalley GF et al. | [Uveitis associated with rifabutin treatment. Apropos of 3 patients]. | 1995 | Klin Monbl Augenheilkd | pmid:7609395 |
| Blum AL et al. | [Functional dyspepsia: approaches to Helicobacter pylori eradication therapy]. | 1995 | Leber Magen Darm | pmid:7609589 |
| Labenz J et al. | [Short-term triple therapy with pantoprazole, clarithromycin and metronidazole in eradication of Helicobacter pylori]. | 1995 | Leber Magen Darm | pmid:7609590 |
| Reppun JI | From prontolyn to biaxin: the half-century of antibiotics. | 1995 | Hawaii Med J | pmid:7628918 |
| Chin DP and Hopewell PC | How to treat bacteraemic Mycobacterium avium complex disease. | 1995 | Lancet | pmid:7564723 |
| Kuhn SM et al. | Treatment of Mycobacterium marinum facial abscess using clarithromycin. | 1995 | Pediatr. Infect. Dis. J. | pmid:7567299 |
| Pollak PT et al. | Delirium probably induced by clarithromycin in a patient receiving fluoxetine. | 1995 | Ann Pharmacother | pmid:7655131 |
| Ozmen MM and Johnson CD | Is short-term triple therapy with lansoprazole, clarithromycin, and metronidazole a definitive answer for Helicobacter pylori eradication? | 1995 | Am. J. Gastroenterol. | pmid:7661197 |
| Savarino V et al. | New insight in the mechanism of omeprazole antimicrobial combinations to eradicate Helicobacter pylori. | 1995 | Am. J. Gastroenterol. | pmid:7717343 |
| Saito H et al. | Therapeutic effect of KRM-1648 with various antimicrobials against Mycobacterium avium complex infection in mice. | 1995 | Tuber. Lung Dis. | pmid:7718848 |
| Hedenmo M and Eriksson BM | Liquid chromatographic determination of the macrolide antibiotics roxithromycin and clarithromycin in plasma by automated solid-phase extraction and electrochemical detection. | 1995 | J Chromatogr A | pmid:7719451 |
| Tseng AL and Walmsley SL | Rifabutin-associated uveitis. | 1995 | Ann Pharmacother | pmid:8573961 |
| Moayyedi P et al. | Efficacy and optimum dose of omeprazole in a new 1-week triple therapy regimen to eradicate Helicobacter pylori. | 1995 | Eur J Gastroenterol Hepatol | pmid:8574714 |
| Fujioka T et al. | Peptic ulcer recurrence after Helicobacter pylori eradication: a 5-year follow-up study. | 1995 | Eur J Gastroenterol Hepatol | pmid:8574733 |
| Deltenre M et al. | Omeprazole-based antimicrobial therapies: results in 198 Helicobacter pylori-positive patients. | 1995 | Eur J Gastroenterol Hepatol | pmid:8574734 |
| Fukuda Y et al. | Combination therapy with mucosal protective agent for the eradication of Helicobacter pylori. | 1995 | Eur J Gastroenterol Hepatol | pmid:8574735 |
| Graham DY | Clarithromycin for treatment of Helicobacter pylori infections. | 1995 | Eur J Gastroenterol Hepatol | pmid:8574737 |
| Takimoto T et al. | Dual therapy with lansoprazole and clarithromycin for eradication of Helicobacter pylori. | 1995 | Eur J Gastroenterol Hepatol | pmid:8574739 |
| Uemura N et al. | Effect of Helicobacter pylori eradication on the healing and recurrence of peptic ulcer: combination therapy with low-dose omeprazole and clarithromycin. | 1995 | Eur J Gastroenterol Hepatol | pmid:8574740 |
| Ishii K et al. | In vitro dissolution tests corresponding to the in vivo dissolution of clarithromycin tablets in the stomach and intestine. | 1995 | Chem. Pharm. Bull. | pmid:8575034 |
| Diehl HG | [One week triple therapy for eradication of Helicobacter pylori infection: simple and effective]. | 1995 | Leber Magen Darm | pmid:8577220 |
| Götz JM et al. | Triple therapy with ranitidine, clarithromycin, and metronidazole in the treatment of Helicobacter pylori. | 1995 | Scand. J. Gastroenterol. Suppl. | pmid:8578230 |
| Pavlopoulou J et al. | Randomized controlled study of clarithromycin versus cefaclor suspensions in the treatment of acute otitis media in children. | 1995 | J Chemother | pmid:8904139 |
| Nishi K et al. | [Effect of clarithromycin on symptoms and mucociliary transport in patients with sino-bronchial syndrome]. | 1995 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:8821993 |
| Smart T | Cryptosporidiosis at ICAAC. | 1995 | GMHC Treat Issues | pmid:11362913 |
| Researchers find new drugs to fight MAC. | 1995 | AIDS Alert | pmid:11362925 | |
| Claussen DW | The most commonly prescribed medications in the United States: Part 3. | 1995 Jul-Aug | Gastroenterol Nurs | pmid:7654815 |
| Hashisaki GT | Update on macrolide antibiotics. | 1995 May-Jun | Am J Otolaryngol | pmid:7661309 |
| Kees F et al. | Serum and cellular pharmacokinetics of clarithromycin 500 mg q.d. and 250 mg b.i.d. in volunteers. | 1995 May-Jun | Infection | pmid:7499006 |
| Sternon J et al. | Azithromycin compared with clarithromycin in the treatment of adult patients with acute purulent tracheobronchitis: a cost of illness study. | 1995 Nov-Dec | J. Int. Med. Res. | pmid:8746608 |
| Stein GE et al. | A preliminary study of clarithromycin versus doxycycline in the treatment of nongonococcal urethritis and mucopurulent cervicitis. | 1995 Nov-Dec | Pharmacotherapy | pmid:8602379 |
| Dalston MO et al. | [Clarithromycin combined with pyrimethamine in cerebral toxoplasmosis--a report of 2 cases]. | 1995 Oct-Dec | Rev. Soc. Bras. Med. Trop. | pmid:8668843 |
| Pinzani V et al. | [Occurrence of anterior uveitis in a HIV patient treated with rifabutin, ethambutol, clarithromycin]. | 1995 Sep-Oct | Therapie | pmid:8571297 |
| Morikawa K et al. | Modulatory effect of antibiotics on cytokine production by human monocytes in vitro. | 1996 | Antimicrob. Agents Chemother. | pmid:8726002 |
| Arain TM et al. | Bioluminescence screening in vitro (Bio-Siv) assays for high-volume antimycobacterial drug discovery. | 1996 | Antimicrob. Agents Chemother. | pmid:8726034 |
| Shafran SD et al. | A comparison of two regimens for the treatment of Mycobacterium avium complex bacteremia in AIDS: rifabutin, ethambutol, and clarithromycin versus rifampin, ethambutol, clofazimine, and ciprofloxacin. Canadian HIV Trials Network Protocol 010 Study Group. | 1996 | N. Engl. J. Med. | pmid:8676931 |
| Shimoyama T et al. | Validity of various diagnostic tests to evaluate cure of Helicobacter pylori infection. | 1996 | J. Gastroenterol. | pmid:8680535 |
| MacConnachie AM | Clarithromycin (klaricid, Abbott). | 1996 | Intensive Crit Care Nurs | pmid:8696027 |
| O'Hara K and Yamamoto K | Reaction of roxithromycin and clarithromycin with macrolide-inactivating enzymes from highly erythromycin-resistant Escherichia coli. | 1996 | Antimicrob. Agents Chemother. | pmid:8849224 |
| Flurer CL | Analysis of macrolide antibiotics by capillary electrophoresis. | 1996 | Electrophoresis | pmid:8900943 |
| Pellegrin I et al. | Activity of rifabutin, clarithromycin, ethambutol, sparfloxacin and amikacin, alone and in combination, against Mycobacterium avium complex in human macrophages. | 1996 | J. Antimicrob. Chemother. | pmid:9182107 |
| Vermot D et al. | Efficacy of clarithromycin versus that of clindamycin for single-dose prophylaxis of experimental streptococcal endocarditis. | 1996 | Antimicrob. Agents Chemother. | pmid:8851620 |
| Hultén K et al. | New pharmacokinetic in vitro model for studies of antibiotic activity against intracellular microorganisms. | 1996 | Antimicrob. Agents Chemother. | pmid:9124830 |
| Xu G et al. | Effect of macrolide antibiotics on macrophage functions. | 1996 | Microbiol. Immunol. | pmid:8865152 |
| Matsuoka N et al. | Inhibitory effect of clarithromycin on costimulatory molecule expression and cytokine production by synovial fibroblast-like cells. | 1996 | Clin. Exp. Immunol. | pmid:9099936 |
| van der Hulst RW et al. | Therapeutic options after failed Helicobacter pylori eradication therapy. | 1996 | Am. J. Gastroenterol. | pmid:8931413 |
| Koeck JL et al. | Disseminated Mycobacterium simiae infection in a patient with AIDS: clinical features and treatment. | 1996 | Clin. Infect. Dis. | pmid:8909856 |
| Ramirez Mayans JA et al. | [Elimination of Helicobacter pylori in patients with recurrent abdominal pain with simultaneous administration of ranitidine, bismuth subsalicylate and clarithromycin]. | 1996 | Acta Gastroenterol. Latinoam. | pmid:9363265 |
| Dammann HG | Therapy with omeprazole and clarithromycin increases serum carbamazepine levels in patients with H. pylori gastritis. | 1996 | Dig. Dis. Sci. | pmid:8617126 |
| Meyboom RH et al. | [Possible potentiation of phenprocoumon by clarithromycin and roxithromycin]. | 1996 | Ned Tijdschr Geneeskd | pmid:8628425 |
| Hunt RH | Eradication of Helicobacter pylori infection. | 1996 | Am. J. Med. | pmid:8644782 |
| Diemer PR et al. | [Rifabutin-induced hypopyon iritis in HIV infection]. | 1996 | Klin Monbl Augenheilkd | pmid:8965476 |
| Labenz J | [Current developments in Helicobacter pylori therapy]. | 1996 | Leber Magen Darm | pmid:8965606 |
| Grau E et al. | Interaction between clarithromycin and oral anticoagulants. | 1996 | Ann Pharmacother | pmid:8968465 |
| Muñoz N et al. | Chemoprevention trial on precancerous lesions of the stomach in Venezuela: summary of study design and baseline data. | 1996 | IARC Sci. Publ. | pmid:8923024 |
| Dhaenens L et al. | In-vitro activities of clarithromycin and other antimicrobial agents against Helicobacter pylori isolated from children. | 1996 | J. Antimicrob. Chemother. | pmid:8877551 |
| Tursi A et al. | Helicobacter pylori eradication helps resolve pyloric and duodenal stenosis. | 1996 | J. Clin. Gastroenterol. | pmid:8877648 |
| Thor P et al. | Dysfunction in gastric myoelectric and motor activity in Helicobacter pylori positive gastritis patients with non-ulcer dyspesia. | 1996 | J. Physiol. Pharmacol. | pmid:8877902 |
| Chen S et al. | [Omeprazole, clarithromycin and amoxicillin therapy for Helicobacter pylori infection]. | 1996 | Zhonghua Nei Ke Za Zhi | pmid:9592303 |
| Liu W et al. | [Clarithromycin combined short-term triple therapies for eradication of Helicobacter pylori infection]. | 1996 | Zhonghua Nei Ke Za Zhi | pmid:9592304 |
| Webb DD | Practice guidelines for treatment of peptic ulcer disease. | 1996 | JAMA | pmid:8827959 |
| Erah PO et al. | Ion-pair high-performance liquid chromatographic assay method for the assessment of clarithromycin stability in aqueous solution and in gastric juice. | 1996 | J. Chromatogr. B, Biomed. Appl. | pmid:8832427 |
| Vangala R and Cernek PK | Hypersensitivity reaction to clarithromycin. | 1996 | Ann Pharmacother | pmid:8833572 |
| Ji B et al. | Bactericidal activities of combinations of new drugs against Mycobacterium leprae in nude mice. | 1996 | Antimicrob. Agents Chemother. | pmid:8834886 |
| Yamamoto T et al. | Activity of KRM-1648 alone or in combination with both ethambutol and kanamycin or clarithromycin against Mycobacterium intracellulare infections in beige mice. | 1996 | Antimicrob. Agents Chemother. | pmid:8834892 |
| Ji B et al. | How effective is KRM-1648 in treatment of disseminated Mycobacterium avium complex infections in beige mice? | 1996 | Antimicrob. Agents Chemother. | pmid:8834894 |
| Dattwyler RJ et al. | Clarithromycin in treatment of early Lyme disease: a pilot study. | 1996 | Antimicrob. Agents Chemother. | pmid:8834900 |
| Riff DS et al. | Triple therapy with lansoprazole, clarithromycin, and amoxicillin for the cure of Helicobacter pylori infection: a short report. | 1996 | Helicobacter | pmid:9398874 |
| Harford W et al. | Double-blind, multicenter evaluation of lansoprazole and amoxicillin dual therapy for the cure of Helicobacter pylori infection. | 1996 | Helicobacter | pmid:9398875 |
| Schwartz H et al. | Seven-day triple therapy with lansoprazole, clarithromycin, and metronidazole for the cure of Helicobacter pylori infection: a short report. | 1996 | Helicobacter | pmid:9398876 |
| Jaup BK | Duodenal ulcer healing after 7-day treatment: a pilot study with lansoprazole, amoxicillin, and clarithromycin. | 1996 | Helicobacter | pmid:9398878 |
| Moayyedi P et al. | Comparison of one or two weeks of lansoprazole, amoxicillin, and clarithromycin in the treatment of Helicobacter pylori. | 1996 | Helicobacter | pmid:9398880 |
| Mégraud F and Malfertheiner P | Treatment of Helicobacter pylori infection: summary of a meeting at the Fourth United European Gastroenterology Week, September 20, 1995. | 1996 | Helicobacter | pmid:9398889 |
| O'Morain C et al. | Double-blind, multicenter, placebo-controlled evaluation of clarithromycin and omeprazole for Helicobacter pylori-associated duodenal ulcer. | 1996 | Helicobacter | pmid:9398893 |
| Welsh L et al. | In vitro activities of azithromycin, clarithromycin, erythromycin, and tetracycline against 13 strains of Chlamydia pneumoniae. | 1996 | Antimicrob. Agents Chemother. | pmid:8787907 |
| Mehaffey PC et al. | Evaluation of in vitro spectra of activity of azithromycin, clarithromycin, and erythromycin tested against strains of Neisseria gonorrhoeae by reference agar dilution, disk diffusion, and Etest methods. | 1996 | J. Clin. Microbiol. | pmid:8789046 |
| Barry AL et al. | Reassessment of methods for testing the susceptibility of Haemophilus influenzae to clarithromycin. | 1996 | J. Antimicrob. Chemother. | pmid:8722555 |
| H. pylori treatment recognized by FDA. | 1996 | Am J Health Syst Pharm | pmid:8725200 |