| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- FEMS Immunol. Med. Microbiol. (1)
- J. Antimicrob. Chemother. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wang F et al. | [Five-day rabeprazole-based triple therapy for helicobacter pylori infection]. | 2004 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:16137055 |
| Li Y et al. | [Efficacy of 4 kinds of triple strategy for Helicobacter pylori eradication]. | 2008 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:19141980 |
| Wu S et al. | [Anti-Helicobacter pylori treatment in patients with idiopathic thrombocytopenic purpura]. | 2009 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:20045922 |
| Wang F et al. | [Antibiotic resistance of Helicobacter pylori]. | 2007 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:17611323 |
| Tang D et al. | [Efficacy of bismuth containing quadruple therapies on Helicobacter pylori eradication in patients with history of antibiotic treatment]. | 2018 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:30124214 |
| Gamova NA | [Drug sensitivity of Ureaplasma urealyticum, persisting in patients with chronic inflammatory diseases of the urogenital tract]. | 2003 Jul-Aug | Zh. Mikrobiol. Epidemiol. Immunobiol. | pmid:12966887 |
| Fabry W et al. | Comparison of the E test and a proportion dilution method for susceptibility testing of Mycobacterium tuberculosis. | 1995 | Zentralbl. Bakteriol. | pmid:9810662 |
| Alter P et al. | [Impediment of cellular immune response under treatment with ticlopidine in a patient with Staphylococcus aureus endocarditis]. | 2000 | Z Kardiol | pmid:11013974 |
| Knothe H | [Short-term therapy of acute respiratory and ORL infections with Clarithromycin]. | 1992 | Z Gesamte Inn Med | pmid:9022402 |
| Hellmeyer L et al. | [Q Fever in pregnancy: a case report and review of the literature]. | 2002 Sep-Oct | Z Geburtshilfe Neonatol | pmid:12395293 |
| Knippig C et al. | Prevalence of H. pylori-infection in family members of H. pylori positive and its influence on the reinfection rate after successful eradication therapy: a two-year follow-up. | 2002 | Z Gastroenterol | pmid:12055660 |
| Lüth S et al. | 4-day triple therapy with rabeprazole, amoxicillin and clarithromycin in the eradication of Helicobacter pylori in patients with peptic ulcer disease--A pilot study. | 2001 | Z Gastroenterol | pmid:11367976 |
| Fritzsch J et al. | [Eosinophilic gastritis after helicobacter pylori eradication]. | 2008 | Z Gastroenterol | pmid:19053006 |
| Bayerdörffer E | [The MACH2 Study: value of inhibiting gastric acid secretion in eradication of Helicobacter pylori with a one week triple therapy protocol]. | 2000 | Z Gastroenterol | pmid:10689750 |
| Schepp W | [Omeprazole + clarithromycin + metronidazole--a new standard for eradication of Helicobacter pylori]. | 1995 | Z Gastroenterol | pmid:7502558 |
| Regnath T et al. | [Real-time PCR assay for rapid detection of clarithromycin-resistant helicobacter pylori in gastric biopsy specimens]. | 2004 | Z Gastroenterol | pmid:15592960 |
| Stolte M et al. | Cure of autoimmune gastritis by Helicobacter pylori eradication in a 21-year-old male. | 1998 | Z Gastroenterol | pmid:9773482 |
| Labenz J and Stolte M | [Is lack of stomach carcinoma prevention by Helicobacter pylori eradication unethical?]. | 1999 | Z Gastroenterol | pmid:10458014 |
| Schilling D et al. | [Eradication of helicobacter pylori: symptomatic treatment of reflux disease?]. | 2002 | Z Gastroenterol | pmid:12122605 |
| Krasz S et al. | [Current value of quinolones in Helicobacter pylori therapy]. | 2011 | Z Gastroenterol | pmid:21811951 |
| Bojarski C et al. | Patients with dyspepsia benefit from eradication of Helicobacter pylori if other organic causes for dyspepsia were carefully ruled out. | 2000 | Z Gastroenterol | pmid:10768243 |
| Schütze K and Hentschel E | Duodenal ulcer healing after 7-day treatment: a pilot study with lansoprazole, amoxicillin and clarithromycin. | 1995 | Z Gastroenterol | pmid:8600661 |
| Tillenburg B et al. | [Helicobacter pylori: pretherapeutic resistance status in Germany (Ruhr area)]. | 1997 | Z Gastroenterol | pmid:9173687 |
| Lee SH et al. | Sequential bilateral lung resection in a patient with Mycobacterium abscessus lung disease refractory to medical treatment. | 2010 | Yonsei Med. J. | pmid:20046529 |
| Jun HJ et al. | Successful treatment of Mycobacterium celatum pulmonary disease in an immunocompetent patient using antimicobacterial chemotherapy and combined pulmonary resection. | 2010 | Yonsei Med. J. | pmid:20879072 |
| Chang JH et al. | A case of acute hepatitis with Mycoplasma pneumoniae infection and transient depression of multiple coagulation factors. | 2008 | Yonsei Med. J. | pmid:19108034 |
| Koh H et al. | Nodular gastritis and pathologic findings in children and young adults with Helicobacter pylori infection. | 2007 | Yonsei Med. J. | pmid:17461522 |
| Tsai SH et al. | Hypoglycemia revisited in the acute care setting. | 2011 | Yonsei Med. J. | pmid:22028152 |
| Kwon YS et al. | Solitary pulmonary nodule due to Mycobacterium intracellulare: the first case in Korea. | 2007 | Yonsei Med. J. | pmid:17326256 |
| Park HK et al. | Clinical characteristics and treatment outcomes of Mycobacterium kansasii lung disease in Korea. | 2010 | Yonsei Med. J. | pmid:20499421 |
| Hatipoglu ON and Tasan Y | A comparative efficacy and safety study of clarithromycin, roxithromycin and erythromycin stearate in mild pneumonia. | 2000 | Yonsei Med. J. | pmid:10957888 |
| Sim YS et al. | Standardized combination antibiotic treatment of Mycobacterium avium complex lung disease. | 2010 | Yonsei Med. J. | pmid:20879056 |
| Jeen YT et al. | Differentiation between reinfection and recrudescence of helicobacter pylori strains using PCR-based restriction fragment length polymorphism analysis. | 2001 | Yonsei Med. J. | pmid:11293500 |
| Lee KY et al. | Two cases of acute leukopenia induced by colchicine with concurrent immunosuppressants use in Behçet's disease. | 2008 | Yonsei Med. J. | pmid:18306487 |
| Chin BS et al. | The characteristics of metallo-β-lactamase-producing gram-negative bacilli isolated from sputum and urine: a single center experience in Korea. | 2011 | Yonsei Med. J. | pmid:21319358 |
| Park HY et al. | Pulmonary disease caused by Mycobacterium xenopi: the first case in Korea. | 2007 | Yonsei Med. J. | pmid:17963348 |
| Qin LH and Tang X | [Preparation and evaluation of clarithromycin emulsion for injection]. | 2006 | Yao Xue Xue Bao | pmid:17184111 |
| Zhang T et al. | [Preparation and evaluation of enteric-coated and taste masking clarithromycin granules]. | 2011 | Yao Xue Xue Bao | pmid:22375429 |
| Ma HL et al. | [Polarographic catalytic wave of clarithromycin and its applications]. | 2004 | Yao Xue Xue Bao | pmid:15700824 |
| Wang J et al. | [Different concentrations of clarithromycin ophthalmic gel for rabbits corneal ulcers induced by Staphylococcus aureus]. | 2008 | Yan Ke Xue Bao | pmid:18709951 |
| Vakil N | Treatment of H. pylori infection: the reality. | 1998 Mar-Apr | Yale J Biol Med | pmid:10378357 |
| Niioka T | Clinical usefulness of limited sampling strategies for estimating AUC of proton pump inhibitors. | 2011 | Yakugaku Zasshi | pmid:21372537 |
| Suzuki A et al. | [Clinical efficacy of kanamycin for Mycobacterium avium complex disease]. | 2008 | Yakugaku Zasshi | pmid:18311066 |
| Matsuo R et al. | [Bitterness of the mixture of clarithromycin dry syrup and carbocisteine preparation--difference between brand name and generic drugs]. | 2008 | Yakugaku Zasshi | pmid:18311069 |
| Omura S et al. | [Research and development of clarithromycin]. | 1992 | Yakugaku Zasshi | pmid:1469609 |
| Salimi A et al. | Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect. | 2016 | Xenobiotica | pmid:26068526 |
| Pan W et al. | Effects of clopidogrel and clarithromycin on the disposition of sibutramine and its active metabolites M1 and M2 in relation to CYP2B6*6 polymorphism. | 2013 | Xenobiotica | pmid:22830954 |
| Kanayama N et al. | Drug-drug interactions in the metabolism of imidafenacin: role of the human cytochrome P450 enzymes and UDP-glucuronic acid transferases, and potential of imidafenacin to inhibit human cytochrome P450 enzymes. | 2007 | Xenobiotica | pmid:17484517 |
| Burt HJ et al. | IC50-based approaches as an alternative method for assessment of time-dependent inhibition of CYP3A4. | 2010 | Xenobiotica | pmid:20230210 |
| Yamamoto T et al. | Prediction of oral clearance from in vitro metabolic data using recombinant CYPs: comparison among well-stirred, parallel-tube, distributed and dispersion models. | 2005 | Xenobiotica | pmid:16192112 |