MeSH term | MeSH ID | Detail |
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Buruli Ulcer | D054312 | 1 associated lipids |
Gastritis, Hypertrophic | D005758 | 1 associated lipids |
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Savarino V et al. | What is the meaning of ranitidine in successful triple-therapy against Helicobacter pylori infection? | 1995 | Am. J. Gastroenterol. | pmid:8540537 |
Gustavson LE et al. | Effect of omeprazole on concentrations of clarithromycin in plasma and gastric tissue at steady state. | 1995 | Antimicrob. Agents Chemother. | pmid:8540719 |
Gelber RH | Successful treatment of a lepromatous patient with clarithromycin. | 1995 | Int. J. Lepr. Other Mycobact. Dis. | pmid:7730711 |
Schepp W | [Omeprazole + clarithromycin + metronidazole--a new standard for eradication of Helicobacter pylori]. | 1995 | Z Gastroenterol | pmid:7502558 |
Widgerow AD et al. | Atypical Mycobacterium and breast surgery. | 1995 | Ann Plast Surg | pmid:7486746 |
Tamaoki J et al. | Effect of clarithromycin on sputum production and its rheological properties in chronic respiratory tract infections. | 1995 | Antimicrob. Agents Chemother. | pmid:7486901 |
Mushatt DM and Witzig RS | Successful treatment of Mycobacterium abscessus infections with multidrug regimens containing clarithromycin. | 1995 | Clin. Infect. Dis. | pmid:7620048 |
Vance E et al. | Pharmacokinetics of clarithromycin and zidovudine in patients with AIDS. | 1995 | Antimicrob. Agents Chemother. | pmid:7574530 |
Singh N and Yu VL | Clarithromycin therapy for Mycobacterium avium complex bacteremia. | 1995 | Ann. Intern. Med. | pmid:7632282 |
Metz DC and Getz HD | Helicobacter pylori gastritis therapy with omeprazole and clarithromycin increases serum carbamazepine levels. | 1995 | Dig. Dis. Sci. | pmid:7720489 |
Atkinson BA et al. | Treatment of Mycobacterium haemophilum infection in a murine model with clarithromycin, rifabutin, and ciprofloxacin. | 1995 | Antimicrob. Agents Chemother. | pmid:8619588 |
Ford A et al. | Clarithromycin-induced digoxin toxicity in a patient with AIDS. | 1995 | Clin. Infect. Dis. | pmid:8645810 |
Gidoh M and Saito H | [Present status of studies on antileprosy drugs]. | 1995 | Nihon Rai Gakkai Zasshi | pmid:8582877 |
Gioulekas J and Hall A | Uveitis associated with rifabutin therapy. | 1995 | Aust N Z J Ophthalmol | pmid:11980079 |
Parasakthi N and Goh KL | Primary and acquired resistance to clarithromycin among Helicobacter pylori strains in Malaysia. | 1995 | Am. J. Gastroenterol. | pmid:7872306 |
Kadayifçi A et al. | Low dose clarithromycin plus omeprazole eradicates Helicobacter pylori in duodenal ulcer disease. | 1995 | Am. J. Gastroenterol. | pmid:7872307 |
Cama VA et al. | Treatment of acute and chronic Cryptosporidium parvum infections in mice using clarithromycin and 14-OH clarithromycin. | 1994 Sep-Oct | J. Eukaryot. Microbiol. | pmid:7804227 |
O'Connor NK and Fris J | Clarithromycin-carbamazepine interaction in a clinical setting. | 1994 Nov-Dec | J Am Board Fam Pract | pmid:7847111 |
Scaglione F et al. | Effect of antibiotics on Bordetella pertussis adhering activity: hypothesis regarding mechanism of action. | 1994 May-Jun | Chemotherapy | pmid:7515782 |
Gersema LM et al. | Suspected drug interaction between cyclosporine and clarithromycin. | 1994 Mar-Apr | J. Heart Lung Transplant. | pmid:8031821 |
Heifets LB | Quantitative cultures and drug susceptibility testing of Mycobacterium avium clinical isolates before and during the antimicrobial therapy. | 1994 Mar-Apr | Res. Microbiol. | pmid:7809471 |
Dautzenberg B | Clinical trials in Mycobacterium avium therapy: lessons to take home. | 1994 Mar-Apr | Res. Microbiol. | pmid:7809472 |
Winter J | Intravenous clarithromycin. | 1994 Mar 16-Apr 5 | Br J Hosp Med | pmid:8032567 |
Mor N et al. | Accumulation of clarithromycin in macrophages infected with Mycobacterium avium. | 1994 Jan-Feb | Pharmacotherapy | pmid:8159593 |
Tessier MH et al. | Clarithromycin for atypical mycobacterial lymphadenitis in non-immunocompromised children. | 1994 Dec 24-31 | Lancet | pmid:7997032 |
Böttger EC | Resistance to drugs targeting protein synthesis in mycobacteria. | 1994 | Trends Microbiol. | pmid:7850212 |
Guelar A et al. | [Therapeutic alternatives for cases of cerebral toxoplasmosis in patients with AIDS: clarithromycin and atovaquone]. | 1994 | Enferm. Infecc. Microbiol. Clin. | pmid:8011719 |
Aspin MM et al. | Comparative study of the safety and efficacy of clarithromycin and amoxicillin-clavulanate in the treatment of acute otitis media in children. | 1994 | J. Pediatr. | pmid:8021763 |
Chaisson RE et al. | Clarithromycin therapy for bacteremic Mycobacterium avium complex disease. A randomized, double-blind, dose-ranging study in patients with AIDS. AIDS Clinical Trials Group Protocol 157 Study Team. | 1994 | Ann. Intern. Med. | pmid:7978715 |
Goldberger M and Masur H | Clarithromycin therapy for Mycobacterium avium complex disease in patients with AIDS: potential and problems. | 1994 | Ann. Intern. Med. | pmid:7978725 |
Thijs JC et al. | Short report: clarithromycin, an alternative to metronidazole in the triple therapy of Helicobacter pylori infection. | 1994 | Aliment. Pharmacol. Ther. | pmid:8186339 |
Gelber RH et al. | Minimal bactericidal concentration of clarithromycin against M. leprae. | 1994 | Int. J. Lepr. Other Mycobact. Dis. | pmid:8189083 |
Xiong JH et al. | Further study of the effectiveness of single doses of clarithromycin and minocycline against Mycobacterium leprae in mice. | 1994 | Int. J. Lepr. Other Mycobact. Dis. | pmid:8189087 |
Paffetti A et al. | [Clarithromycin in pediatric age. Personal experience]. | 1994 | Minerva Pediatr. | pmid:8084327 |
Ohgaki N | Bacterial biofilm in chronic airway infection. | 1994 | Kansenshogaku Zasshi | pmid:8138670 |
Yasuda H et al. | Interaction between clarithromycin and biofilms formed by Staphylococcus epidermidis. | 1994 | Antimicrob. Agents Chemother. | pmid:8141568 |
Uveitis associated with rifabutin therapy. | 1994 | MMWR Morb. Mortal. Wkly. Rep. | pmid:8072478 | |
Honeybourne D et al. | The levels of clarithromycin and its 14-hydroxy metabolite in the lung. | 1994 | Eur. Respir. J. | pmid:7925906 |
Gad A and Unge P | Antibacterial therapy of Helicobacter pylori-associated peptic ulcer disease: a new strategy. The Swedes go for it. | 1994 | J. Clin. Gastroenterol. | pmid:7930437 |
Braegger CP and Nadal D | Clarithromycin and pseudomembranous enterocolitis. | 1994 | Lancet | pmid:7904702 |
Nishimura M et al. | [Therapeutic study on biofilm of the urinary tract using a severely complicated bladder model (biofilm model of the urinary tract)--experimental study using an automatic simulator of urinary antimicrobial agent concentration, and clinical study]. | 1994 | Kansenshogaku Zasshi | pmid:7909830 |
Wallace RJ et al. | Initial clarithromycin monotherapy for Mycobacterium avium-intracellulare complex lung disease. | 1994 | Am. J. Respir. Crit. Care Med. | pmid:8173775 |
Bermudez LE et al. | Clarithromycin, dapsone, and a combination of both used to treat or prevent disseminated Mycobacterium avium infection in beige mice. | 1994 | Antimicrob. Agents Chemother. | pmid:7695252 |
Mor N et al. | Effects of clarithromycin and rifabutin alone and in combination on intracellular and extracellular replication of Mycobacterium avium. | 1994 | Antimicrob. Agents Chemother. | pmid:7695255 |
Calì G et al. | [Clarithromycin in the treatment of oral infections]. | 1994 | Minerva Stomatol | pmid:7700226 |
Reed PI | The ECP-IM intervention study. | 1994 | Eur. J. Cancer Prev. | pmid:7735056 |
Kodama R et al. | Combination therapy with clarithromycin and sofalcone for eradication of Helicobacter pylori. | 1994 | Eur J Gastroenterol Hepatol | pmid:7735929 |
Olliaro P et al. | In-vitro and in-vivo activity of rifabutin against Toxoplasma gondii. | 1994 | J. Antimicrob. Chemother. | pmid:7706160 |
Marco ML et al. | [Rhodococcus equi pneumonia in patients with AIDS]. | 1994 | Arch. Bronconeumol. | pmid:7827773 |
Yamada S et al. | [A child with iritis due to Chlamydia pneumoniae infection]. | 1994 | Kansenshogaku Zasshi | pmid:7876679 |