MeSH term | MeSH ID | Detail |
---|---|---|
Immune Reconstitution Inflammatory Syndrome | D054019 | 1 associated lipids |
Serositis | D012700 | 1 associated lipids |
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Huang CC et al. | In vitro activity of aminoglycosides, clofazimine, d-cycloserine and dapsone against 83 Mycobacterium avium complex clinical isolates. | 2018 | J Microbiol Immunol Infect | pmid:28705770 |
Tang D et al. | [Efficacy of bismuth containing quadruple therapies on Helicobacter pylori eradication in patients with history of antibiotic treatment]. | 2018 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:30124214 |
Byeon JY et al. | Effects of genetic polymorphisms of CYP2C19 on the pharmacokinetics of zolpidem. | 2018 | Arch. Pharm. Res. | pmid:30117082 |
Park CG et al. | Clinical relevance of point mutations in the 23S rRNA gene in Helicobacter pylori eradication: A prospective, observational study. | 2018 | Medicine (Baltimore) | pmid:30113472 |
Morgene MF et al. | HaCaT epithelial cells as an innovative novel model of rhinovirus infection and impact of clarithromycin treatment on infection kinetics. | 2018 | Virology | pmid:30077071 |
Berende A et al. | Cost-effectiveness of longer-term versus shorter-term provision of antibiotics in patients with persistent symptoms attributed to Lyme disease. | 2018 | PLoS ONE | pmid:29608590 |
Mabe K et al. | Randomized controlled trial: PPI-based triple therapy containing metronidazole versus clarithromycin as first-line treatment for Helicobacter pylori in adolescents and young adults in Japan. | 2018 | J. Infect. Chemother. | pmid:29605555 |
Chen SA et al. | HLA-A*02:07 Allele Associates with Clarithromycin-Induced Cutaneous Adverse Drug Reactions in Chinese Patients. | 2018 | Basic Clin. Pharmacol. Toxicol. | pmid:29575644 |
van Dyk M et al. | Assessment of inter-racial variability in CYP3A4 activity and inducibility among healthy adult males of Caucasian and South Asian ancestries. | 2018 | Eur. J. Clin. Pharmacol. | pmid:29572563 |
Chen J et al. | Application of next-generation sequencing to characterize novel mutations in clarithromycin-susceptible Helicobacter pylori strains with A2143G of 23S rRNA gene. | 2018 | Ann. Clin. Microbiol. Antimicrob. | pmid:29562911 |
RodrÃguez-Sevilla G et al. | Non-Tuberculous Mycobacteria multispecies biofilms in cystic fibrosis: development of an in vitro Mycobacterium abscessus and Pseudomonas aeruginosa dual species biofilm model. | 2018 | Int. J. Med. Microbiol. | pmid:29555180 |
Cho EH et al. | Differences in drug susceptibility pattern between Mycobacterium avium and Mycobacterium intracellulare isolated in respiratory specimens. | 2018 | J. Infect. Chemother. | pmid:29223615 |
Compain F et al. | In vitro activity of tedizolid against the Mycobacterium abscessus complex. | 2018 | Diagn. Microbiol. Infect. Dis. | pmid:29217419 |
Li H et al. | Inappropriate treatment in Helicobacter pylori eradication failure: a retrospective study. | 2018 | Scand. J. Gastroenterol. | pmid:29214879 |
Jung JH et al. | Clinical Outcomes of Standard Triple Therapy Plus Probiotics or Concomitant Therapy for Infection. | 2018 | Gut Liver | pmid:29212313 |
Deng J et al. | Lack of additional effects of long-term, low-dose clarithromycin combined treatment compared with topical steroids alone for chronic rhinosinusitis in China: a randomized, controlled trial. | 2018 | Int Forum Allergy Rhinol | pmid:29195025 |
De Lorenzi G et al. | Mycobacterium genavense Infection in a Domestic Ferret (Mustela putorius furo). | 2018 | Top Companion Anim Med | pmid:30502861 |
McNicholl AG et al. | Probiotic supplementation with Lactobacillus plantarum and Pediococcus acidilactici for Helicobacter pylori therapy: A randomized, double-blind, placebo-controlled trial. | 2018 | Helicobacter | pmid:30141228 |
Mahachai V et al. | Helicobacter pylori management in ASEAN: The Bangkok consensus report. | 2018 | J. Gastroenterol. Hepatol. | pmid:28762251 |
Choi IJ et al. | Helicobacter pylori Therapy for the Prevention of Metachronous Gastric Cancer. | 2018 | N. Engl. J. Med. | pmid:29562147 |