MeSH term | MeSH ID | Detail |
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Sacroiliitis | D058566 | 1 associated lipids |
Chlamydial Pneumonia | D061387 | 2 associated lipids |
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Parola D et al. | [Efficacy and safety of clarithromycin in the treatment of community-acquired pneumonia]. | 2000 | Recenti Prog Med | pmid:10705778 |
Fonquernie L et al. | [Pseudotumoral abdominal granuloma concomitant with immune reconstitution after antiretroviral treatment]. | 2000 | Presse Med | pmid:10705894 |
Luman W et al. | One week triple therapy for Helicobacter pylori associated duodenal ulcer disease. | 1999 | Singapore Med J | pmid:10709423 |
Coelho LG et al. | Once-daily Helicobacter pylori treatment to family members of gastric cancer patients. | 2000 | Am. J. Gastroenterol. | pmid:10710099 |
Pilotto A et al. | In vitro activity of rifabutin against strains of Helicobacter pylori resistant to metronidazole and clarithromycin. | 2000 | Am. J. Gastroenterol. | pmid:10710100 |
Kearney DJ and Brousal A | Treatment of Helicobacter pylori infection in clinical practice in the United States: results from 224 patients. | 2000 | Dig. Dis. Sci. | pmid:10711436 |
Lõivukene K et al. | Metronidazole and clarithromycin susceptibility and the subtypes of vacA of Helicobacter pylori isolates in Estonia. | 2000 | Scand. J. Infect. Dis. | pmid:10716079 |
Edlund C et al. | Comparative effects of moxifloxacin and clarithromycin on the normal intestinal microflora. | 2000 | Scand. J. Infect. Dis. | pmid:10716083 |
Ani AE et al. | Antimicrobial susceptibility test of Helicobacter pylori isolated from Jos, Nigeria. | 1999 Nov-Dec | Trans. R. Soc. Trop. Med. Hyg. | pmid:10717760 |
Tran JQ et al. | Comparison of the abilities of grepafloxacin and clarithromycin to eradicate potential bacterial pathogens from the sputa of patients with chronic bronchitis: influence of pharmacokinetic and pharmacodynamic variables. | 2000 | J. Antimicrob. Chemother. | pmid:10719007 |
Brophy DF et al. | Pharmacokinetic interaction between amprenavir and clarithromycin in healthy male volunteers. | 2000 | Antimicrob. Agents Chemother. | pmid:10722500 |
Numazaki K et al. | Therapeutic effect of clarithromycin for respiratory-tract infections in children caused by Chlamydia pneumoniae. Research Group of Sapporo for Pediatric Chlamydial Infections. | 2000 | Int. J. Antimicrob. Agents | pmid:10724028 |
Gomollón F et al. | [Does eliminating Helicobacter pylori mean the healing of the duodenal ulcer? The results of a prospective study in Spain]. | 2000 | Gastroenterol Hepatol | pmid:10726384 |
Telenti A and Iseman M | Drug-resistant tuberculosis: what do we do now? | 2000 | Drugs | pmid:10730543 |
Lehmann FS et al. | Effect of ornidazole and clarithromycin resistance on eradication of Helicobacter pylori in peptic ulcer disease. | 2000 | Aliment. Pharmacol. Ther. | pmid:10735923 |
Miwa H et al. | Cure of Helicobacter pylori infection does not improve symptoms in non-ulcer dyspepsia patients-a double-blind placebo-controlled study. | 2000 | Aliment. Pharmacol. Ther. | pmid:10735925 |
Spinzi GC et al. | Seven-day triple therapy with ranitidine bismuth citrate or omeprazole and two antibiotics for eradication of Helicobacter pylori in duodenal ulcer: a multicentre, randomized, single-blind study. | 2000 | Aliment. Pharmacol. Ther. | pmid:10735926 |
Blackington E | The gastric demon. An update on Helicobacter pylori infection. | 1999 | Adv Nurse Pract | pmid:10745720 |
Paton R et al. | Susceptibility testing of Haemophilus influenzae to clarithromycin. | 2000 | J. Antimicrob. Chemother. | pmid:10747833 |
Shashidhar H et al. | A prospective trial of lansoprazole triple therapy for pediatric Helicobacter pylori infection. | 2000 | J. Pediatr. Gastroenterol. Nutr. | pmid:10749411 |