| MeSH term | MeSH ID | Detail |
|---|---|---|
| Sacroiliitis | D058566 | 1 associated lipids |
| Chlamydial Pneumonia | D061387 | 2 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Versalovic J et al. | Point mutations in the 23S rRNA gene of Helicobacter pylori associated with different levels of clarithromycin resistance. | 1997 | J. Antimicrob. Chemother. | pmid:9301997 |
| Hoffman JS | Pharmacological therapy of Helicobacter pylori infection. | 1997 | Semin. Gastrointest. Dis. | pmid:9232728 |
| Sano M et al. | [A clinical study on combination therapy of antimicrobial agents for complicated urinary tract infection--with special reference to combination with clarithromycin]. | 1997 | Nippon Hinyokika Gakkai Zasshi | pmid:9234616 |
| Saluja A et al. | A surgical wound infection due to Mycobacterium chelonae successfully treated with clarithromycin. | 1997 | Dermatol Surg | pmid:9236871 |
| Gisbert JP et al. | [One-week treatment with omeprazole, clarithromycin and amoxicillin: high efficacy in the eradication of Helicobacter pylori and cicatrization of duodenal ulcer]. | 1997 | Med Clin (Barc) | pmid:9190436 |
| Damianos AJ and McGarrity TJ | Treatment strategies for Helicobacter pylori infection. | 1997 | Am Fam Physician | pmid:9191460 |
| Ebell MH et al. | Evaluation of the dyspeptic patient: a cost-utility study. | 1997 | J Fam Pract | pmid:9191627 |
| Griffith DE | Nontuberculous mycobacteria. | 1997 | Curr Opin Pulm Med | pmid:9193860 |
| Villanueva A et al. | Report on an outbreak of postinjection abscesses due to Mycobacterium abscessus, including management with surgery and clarithromycin therapy and comparison of strains by random amplified polymorphic DNA polymerase chain reaction. | 1997 | Clin. Infect. Dis. | pmid:9195073 |
| Woo MS et al. | Pediatric transplant grand rounds. A case presentation: skin lesions in a post-lung transplant patient. | 1997 | Pediatr Transplant | pmid:10084776 |
| Taylor DE et al. | Cloning and sequence analysis of two copies of a 23S rRNA gene from Helicobacter pylori and association of clarithromycin resistance with 23S rRNA mutations. | 1997 | Antimicrob. Agents Chemother. | pmid:9420030 |
| Reed PI and Johnston BJ | Treatment of Helicobacter pylori infection. | 1997 | Biomed. Pharmacother. | pmid:9084725 |
| Plemmons RM et al. | Osteomyelitis due to Mycobacterium haemophilum in a cardiac transplant patient: case report and analysis of interactions among clarithromycin, rifampin, and cyclosporine. | 1997 | Clin. Infect. Dis. | pmid:9142810 |
| Khan AA et al. | Activity of trovafloxacin in combination with other drugs for treatment of acute murine toxoplasmosis. | 1997 | Antimicrob. Agents Chemother. | pmid:9145840 |
| Collins L and Franzblau SG | Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium. | 1997 | Antimicrob. Agents Chemother. | pmid:9145860 |
| Lounis N et al. | Comparative activities of amikacin against Mycobacterium avium complex in nude and beige mice. | 1997 | Antimicrob. Agents Chemother. | pmid:9145892 |
| Spinzi G et al. | Randomized study comparing omeprazole plus amoxycillin versus omeprazole plus clarithromycin for eradication of Helicobacter pylori. | 1997 | Aliment. Pharmacol. Ther. | pmid:9146769 |
| Peterson WL | The role of antisecretory drugs in the treatment of Helicobacter pylori infection. | 1997 | Aliment. Pharmacol. Ther. | pmid:9146787 |
| Pendland SL et al. | Comparison of charcoal- and starch-based media for testing susceptibilities of Legionella species to macrolides, azalides, and fluoroquinolones. | 1997 | J. Clin. Microbiol. | pmid:9350781 |
| Banerjee DK et al. | Experimental evaluation of possible new short-term drug regimens for treatment of multibacillary leprosy. | 1997 | Antimicrob. Agents Chemother. | pmid:9021187 |
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| Wang XM et al. | [Time course of disappearance of Helicobacter pylori after topical therapy and new triple therapy]. | 1997 | Nihon Shokakibyo Gakkai Zasshi | pmid:9028149 |
| MacÃas J et al. | Rhodococcus or mycobacterium? An example of misdiagnosis in HIV infection. | 1997 | AIDS | pmid:9030376 |
| Rodrigues AD and Wong SL | Application of human liver microsomes in metabolism-based drug-drug interactions: in vitro-in vivo correlations and the Abbott Laboratories experience. | 1997 | Adv. Pharmacol. | pmid:9342173 |
| Yasui N et al. | Carbamazepine toxicity induced by clarithromycin coadministration in psychiatric patients. | 1997 | Int Clin Psychopharmacol | pmid:9347384 |
| May T et al. | Comparison of combination therapy regimens for treatment of human immunodeficiency virus-infected patients with disseminated bacteremia due to Mycobacterium avium. ANRS Trial 033 Curavium Group. Agence Nationale de Recherche sur le Sida. | 1997 | Clin. Infect. Dis. | pmid:9314450 |
| Wright DH | Regression of mucosa-associated lymphoid-tissue lymphoma after eradication of Helicobacter pylori. | 1997 | Lancet | pmid:9314895 |
| Picardeau M et al. | Use of different molecular typing techniques for bacteriological follow-up in a clinical trial with AIDS patients with Mycobacterium avium bacteremia. | 1997 | J. Clin. Microbiol. | pmid:9316897 |
| Chey WD et al. | Bismuth subsalicylate instead of metronidazole with lansoprazole and clarithromycin for Helicobacter pylori infection: a randomized trial. | 1997 | Am. J. Gastroenterol. | pmid:9317068 |
| Pipkin GA et al. | Clarithromycin dual therapy regimens for eradication of Helicobacter pylori: a review. | 1997 | Helicobacter | pmid:9421117 |
| Tompkins DS et al. | Failed treatment of Helicobacter pylori infection associated with resistance to clarithromycin. | 1997 | Helicobacter | pmid:9421121 |
| Taylor JL et al. | Pharmacoeconomic comparison of treatments for the eradication of Helicobacter pylori. | 1997 | Arch. Intern. Med. | pmid:8996045 |
| Drugs for treatment of peptic ulcers. | 1997 | Med Lett Drugs Ther | pmid:8996458 | |
| Stone GG et al. | A PCR-oligonucleotide ligation assay to determine the prevalence of 23S rRNA gene mutations in clarithromycin-resistant Helicobacter pylori. | 1997 | Antimicrob. Agents Chemother. | pmid:9056021 |
| Moayyedi P et al. | Patient factors that predict failure of omeprazole, clarithromycin, and tinidazole to eradicate Helicobacter pylori. | 1997 | J. Gastroenterol. | pmid:9058291 |
| Dautzenberg B | Rationale for the prevention of disseminated Mycobacterium avium-intracellulare complex disease. | 1997 | Drugs | pmid:9358194 |
| Reisner BS et al. | Electron microscopic analysis of Mycobacterium avium complex isolates exposed to ciprofloxacin, rifabutin, ethambutol and clarithromycin. | 1997 | Int. J. Tuberc. Lung Dis. | pmid:9432376 |
| Lerang F et al. | Highly effective second-line anti-Helicobacter pylori therapy in patients with previously failed metronidazole-based therapy. | 1997 | Scand. J. Gastroenterol. | pmid:9438318 |
| Akiyama H et al. | Biofilm formation of Staphylococcus aureus strains isolated from impetigo and furuncle: role of fibrinogen and fibrin. | 1997 | J. Dermatol. Sci. | pmid:9438901 |
| Bazzoli F and Pozzato P | Therapy of H. pylori infection. | 1997 | J. Physiol. Pharmacol. | pmid:9440054 |
| Dixon JS et al. | Ranitidine bismuth citrate plus clarithromycin for the eradication of H. pylori. | 1997 | J. Physiol. Pharmacol. | pmid:9440055 |
| Yatsunami J et al. | Clarithromycin is a potent inhibitor of tumor-induced angiogenesis. | 1997 | Res Exp Med (Berl) | pmid:9440137 |
| Konishi T and Nakao M | Antibiotic treatment in mice infected with Japanese Borrelia garinii: efficacy of ceftriaxone for eradicating the infection induced by Ixodes persulcatus tick bites. | 1997 | Microbiol. Immunol. | pmid:9087959 |
| GarcÃa-de-Lomas J et al. | Antimicrobial susceptibility of Streptococcus pneumoniae isolated from pediatric carriers in Spain. | 1997 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9063666 |
| Weiss I et al. | Serotyping and susceptibility to macrolides and other antimicrobial drugs of Streptococcus pyogenes isolated from patients with invasive diseases in southern Israel. | 1997 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9063669 |
| Price J and Hamilton W | Pragmatic eradication of H. pylori. | 1997 | Br J Gen Pract | pmid:9474836 |
| Feldman C et al. | Roxithromycin, clarithromycin, and azithromycin attenuate the injurious effects of bioactive phospholipids on human respiratory epithelium in vitro. | 1997 | Inflammation | pmid:9429912 |
| Misiewicz JJ | Management of Helicobacter pylori-related disorders. | 1997 | Eur J Gastroenterol Hepatol | pmid:9160212 |
| Williams MP et al. | Seven-day treatment for Helicobacter pylori infection: ranitidine bismuth citrate plus clarithromycin and tetracycline hydrochloride. | 1997 | Aliment. Pharmacol. Ther. | pmid:9305479 |
| Hultén K et al. | Macrolide resistance in Helicobacter pylori: mechanism and stability in strains from clarithromycin-treated patients. | 1997 | Antimicrob. Agents Chemother. | pmid:9371366 |
| Sánchez-Nuñez ML et al. | Clarithromycin in the treatment of cyclosporin-associated gingival hyperplasia. | 1997 | Nephrol. Dial. Transplant. | pmid:9306384 |
| Finkenbine R and Gill HS | Case of mania due to prednisone-clarithromycin interaction. | 1997 | Can J Psychiatry | pmid:9307841 |
| Gisbert JP et al. | Unhealed duodenal ulcers despite Helicobacter pylori eradication. | 1997 | Scand. J. Gastroenterol. | pmid:9246702 |
| Barry AL et al. | In vitro activity of the new ketolide HMR 3004 compared to an azalide and macrolides against Streptococcus pneumoniae and Haemophilus influenzae. | 1997 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9405952 |
| Fuursted K | Evaluation of the post-antibiotic effect of six anti-mycobacterial agents against Mycobacterium avium by the Bactec radiometric method. | 1997 | J. Antimicrob. Chemother. | pmid:9249202 |
| Polis MA et al. | Clarithromycin lowers plasma zidovudine levels in persons with human immunodeficiency virus infection. | 1997 | Antimicrob. Agents Chemother. | pmid:9257746 |
| Shibata K et al. | Bactericidal effect of ecabet sodium on clarithromycin- and metronidazole-resistant clinical isolates of Helicobacter pylori. | 1997 | Jpn J Antibiot | pmid:9258741 |
| Böttger EC et al. | Prophylaxis of mycobacterial infection and acquired drug resistance. | 1997 | J. Antimicrob. Chemother. | pmid:9249224 |
| Sato K et al. | [Anti-Mycobacterium avium complex activities of KRM-1648, clarithromycin and levofloxacin in 7HSF medium at peak or average blood concentrations after their oral administration of clinical dosages]. | 1997 | Kekkaku | pmid:9259129 |
| Peloquin CA and Berning SE | Advice on treatment of Mycobacterium avium complex infection. | 1997 | Am J Health Syst Pharm | pmid:9161632 |
| OÄŸuz O et al. | Conjunctival involvement in familial chronic benign pemphigus (Hailey-Hailey disease). | 1997 | Int. J. Dermatol. | pmid:9169328 |
| Mitsuyama T et al. | Neutrophil-induced endothelial cell damage: inhibition by a 14-membered ring macrolide through the action of nitric oxide. | 1997 | Int. Arch. Allergy Immunol. | pmid:9338603 |
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| Walsh D et al. | One week treatment for Helicobacter pylori infection. | 1997 | Arch. Dis. Child. | pmid:9166031 |
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| Midolo PD et al. | Antimicrobial resistance testing of Helicobacter pylori: a comparison of Etest and disk diffusion methods. | 1997 | Pathology | pmid:9423225 |
| Phull PS et al. | Lansoprazole plus clarithromycin: evaluation of a new dual therapy for Helicobacter pylori eradication. | 1996 Oct-Nov | Br J Clin Pract | pmid:9015906 |
| Peeling RW and Brunham RC | Chlamydiae as pathogens: new species and new issues. | 1996 Oct-Dec | Emerging Infect. Dis. | pmid:8969247 |
| Prescott LM | Clarithromycin for MAC prevention offers additional benefits. | 1996 May-Jun | Posit Aware | pmid:11363431 |
| Mertl SL | The role of clarithromycin in the prophylaxis of disseminated Mycobacterium avium-intracellulare infection in patients with AIDS. | 1996 May-Jun | Pharmacotherapy | pmid:8726597 |
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| Nightingale SL | From the Food and Drug Administration. | 1996 May 22-29 | JAMA | pmid:8622234 |
| Sketris IS et al. | Possible role of the intestinal P-450 enzyme system in a cyclosporine-clarithromycin interaction. | 1996 Mar-Apr | Pharmacotherapy | pmid:8820476 |
| Akamatsu H et al. | Enhanced effect of clarithromycin on neutrophil function in vitro. | 1996 Mar-Apr | J. Int. Med. Res. | pmid:8737228 |
| Papp J et al. | Efficacy of nizatidine, clarithromycin and bismuth subcitrate therapy for Helicobacter pylori eradication in duodenal ulcer patients--a preliminary report. | 1996 Jul-Aug | Br J Clin Pract | pmid:8794601 |
| Tursi A et al. | One-week low-dose triple therapy vs. two-week medium-dose double therapy for H.pylori infection. | 1996 Jul-Aug | Hepatogastroenterology | pmid:8884304 |
| Amsden GW | Erythromycin, clarithromycin, and azithromycin: are the differences real? | 1996 Jan-Feb | Clin Ther | pmid:8851453 |
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| Morikawa K et al. | Modulatory effect of antibiotics on cytokine production by human monocytes in vitro. | 1996 | Antimicrob. Agents Chemother. | pmid:8726002 |
| Arain TM et al. | Bioluminescence screening in vitro (Bio-Siv) assays for high-volume antimycobacterial drug discovery. | 1996 | Antimicrob. Agents Chemother. | pmid:8726034 |
| Berg-Candolfi M and Candolfi E | Depression of the N-demethylation of erythromycin, azithromycin, clarithromycin and clindamycin in murine Toxoplasma infection. | 1996 | Int. J. Parasitol. | pmid:9024879 |
| Griffith DE et al. | Varying dosages of rifabutin affect white blood cell and platelet counts in human immunodeficiency virus--negative patients who are receiving multidrug regimens for pulmonary Mycobacterium avium complex disease. | 1996 | Clin. Infect. Dis. | pmid:8953085 |
| Matsuoka N et al. | Inhibitory effect of clarithromycin on costimulatory molecule expression and cytokine production by synovial fibroblast-like cells. | 1996 | Clin. Exp. Immunol. | pmid:9099936 |
| Kuo CC et al. | In vitro activities of azithromycin, clarithromycin, and other antibiotics against Chlamydia pneumoniae. | 1996 | Antimicrob. Agents Chemother. | pmid:8913488 |
| Aoyama T et al. | Efficacy of short-term treatment of pertussis with clarithromycin and azithromycin. | 1996 | J. Pediatr. | pmid:8917247 |
| Dammann HG | Therapy with omeprazole and clarithromycin increases serum carbamazepine levels in patients with H. pylori gastritis. | 1996 | Dig. Dis. Sci. | pmid:8617126 |
| Kondoh K et al. | Inhibitory activity of clarithromycin on biofilm synthesis with Pseudomonas aeruginosa. | 1996 | Acta Otolaryngol Suppl | pmid:8908271 |
| Moreno JA et al. | Significant increase in eradication rates of Helicobacter pylori infection with two consecutive dual therapies (omeprazole and amoxycillin or omeprazole and clarithromycin). A randomized study in 450 Spanish patients. | 1996 | J. Gastroenterol. | pmid:8959519 |
| Satoh K et al. | Efficacy of clarithromycin in eradicating Helicobacter pylori. | 1996 | J. Gastroenterol. | pmid:8959520 |
| Shimoyama T et al. | Ecabet sodium eradicates Helicobacter pylori infection in gastric ulcer patients. | 1996 | J. Gastroenterol. | pmid:8959522 |
| Chen S et al. | [Omeprazole, clarithromycin and amoxicillin therapy for Helicobacter pylori infection]. | 1996 | Zhonghua Nei Ke Za Zhi | pmid:9592303 |
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| Webb DD | Practice guidelines for treatment of peptic ulcer disease. | 1996 | JAMA | pmid:8827959 |
| Erah PO et al. | Ion-pair high-performance liquid chromatographic assay method for the assessment of clarithromycin stability in aqueous solution and in gastric juice. | 1996 | J. Chromatogr. B, Biomed. Appl. | pmid:8832427 |
| Vangala R and Cernek PK | Hypersensitivity reaction to clarithromycin. | 1996 | Ann Pharmacother | pmid:8833572 |
| Riff DS et al. | Triple therapy with lansoprazole, clarithromycin, and amoxicillin for the cure of Helicobacter pylori infection: a short report. | 1996 | Helicobacter | pmid:9398874 |
| Harford W et al. | Double-blind, multicenter evaluation of lansoprazole and amoxicillin dual therapy for the cure of Helicobacter pylori infection. | 1996 | Helicobacter | pmid:9398875 |
| Schwartz H et al. | Seven-day triple therapy with lansoprazole, clarithromycin, and metronidazole for the cure of Helicobacter pylori infection: a short report. | 1996 | Helicobacter | pmid:9398876 |
| Barry AL et al. | Reassessment of methods for testing the susceptibility of Haemophilus influenzae to clarithromycin. | 1996 | J. Antimicrob. Chemother. | pmid:8722555 |
| H. pylori treatment recognized by FDA. | 1996 | Am J Health Syst Pharm | pmid:8725200 |