MeSH term | MeSH ID | Detail |
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Abortion, Spontaneous | D000022 | 12 associated lipids |
Abnormalities, Drug-Induced | D000014 | 10 associated lipids |
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Ramzy I et al. | GENETIC MUTATIONS AFFECTING THE FIRST LINE ERADICATION THERAPY OF Helicobacter pylori-INFECTED EGYPTIAN PATIENTS. | 2016 | Rev. Inst. Med. Trop. Sao Paulo | pmid:27982354 |
Noda H et al. | A Novel Potassium-Competitive Acid Blocker Improves the Efficacy of Clarithromycin-containing 7-day Triple Therapy against Helicobacter pylori. | 2016 | J Gastrointestin Liver Dis | pmid:27689190 |
Donzelli A | Helicobacter pylori Eradication? | 2016 | Gastroenterology | pmid:27590693 |
Patton PH et al. | Anti-tuberculous therapy for maintenance of remission in Crohn's disease. | 2016 | Cochrane Database Syst Rev | pmid:27444319 |
Christl I et al. | Clarithromycin and Tetracycline Binding to Soil Humic Acid in the Absence and Presence of Calcium. | 2016 | Environ. Sci. Technol. | pmid:27438991 |
Luo XF et al. | Establishment of a nested-ASP-PCR method to determine the clarithromycin resistance of Helicobacter pylori. | 2016 | World J. Gastroenterol. | pmid:27433095 |
Hirasawa K et al. | Macrolide Antibiotics Exhibit Cytotoxic Effect under Amino Acid-Depleted Culture Condition by Blocking Autophagy Flux in Head and Neck Squamous Cell Carcinoma Cell Lines. | 2016 | PLoS ONE | pmid:27977675 |
Mougari F et al. | Infections caused by Mycobacterium abscessus: epidemiology, diagnostic tools and treatment. | 2016 | Expert Rev Anti Infect Ther | pmid:27690688 |
Laird-Fick HS et al. | Gastric adenocarcinoma: the role of Helicobacter pylori in pathogenesis and prevention efforts. | 2016 | Postgrad Med J | pmid:27222587 |
Phiphatpatthamaamphan K et al. | Effect of IL-1 Polymorphisms, CYP2C19 Genotype and Antibiotic Resistance on Helicobacter pylori Eradication Comparing Between 10-day Sequential Therapy and 14-day Standard Triple Therapy with Four-Times-Daily-Dosing of Amoxicillin in Thailand: a Prospective Randomized Study. | 2016 | Asian Pac. J. Cancer Prev. | pmid:27221874 |
Kim SY et al. | Successful antibiotic treatment of pulmonary disease caused by Mycobacterium abscessus subsp. abscessus with C-to-T mutation at position 19 in erm(41) gene: case report. | 2016 | BMC Infect. Dis. | pmid:27188784 |
Klesiewicz K et al. | Anti-Helicobacter pylori activity of some newly synthesized derivatives of xanthone. | 2016 | J. Antibiot. | pmid:27025351 |
Kawashima K et al. | Successful eradication of Helicobacter pylori infection with vonoprazan-based triple therapy after failure of PPI-based triple therapy. | 2016 | Dig Liver Dis | pmid:27012448 |
Belz D et al. | Mycobacterium marinum infection initially diagnosed as metastatic Crohn's disease. | 2016 | J Eur Acad Dermatol Venereol | pmid:25510444 |
Vannarath S et al. | Antibiotic Resistant Pattern of Helicobacter Pylori Infection Based on Molecular Tests in Laos. | 2016 | Asian Pac. J. Cancer Prev. | pmid:26838225 |
Miyamoto S et al. | Analysis of Helicobacter pylori genotypes in clinical gastric wash samples. | 2016 | Tumour Biol. | pmid:26825980 |
Bohnert JA et al. | Novel Piperazine Arylideneimidazolones Inhibit the AcrAB-TolC Pump in Escherichia coli and Simultaneously Act as Fluorescent Membrane Probes in a Combined Real-Time Influx and Efflux Assay. | 2016 | Antimicrob. Agents Chemother. | pmid:26824939 |
Shin WG et al. | Eradication Rates of Helicobacter pylori in Korea Over the Past 10 years and Correlation of the Amount of Antibiotics Use: Nationwide Survey. | 2016 | Helicobacter | pmid:26470999 |
Yoon H et al. | Effects of N-acetylcysteine on First-Line Sequential Therapy for Helicobacter pylori Infection: A Randomized Controlled Pilot Trial. | 2016 | Gut Liver | pmid:26347514 |
Liou JM et al. | Sequential therapy for 10 days versus triple therapy for 14 days in the eradication of in the community and hospital populations: a randomised trial. | 2016 | Gut | pmid:26338825 |