clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

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Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Abortion, Spontaneous D000022 12 associated lipids
Abnormalities, Drug-Induced D000014 10 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

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Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


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Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

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What genes are associated with clarithromycin?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Hoigné-Löpfe I and Jöhr M Psychiatric symptoms after anesthesia: antibiomania or Hoigné's syndrome? 2006 Paediatr Anaesth pmid:16618314
Przybylo HJ et al. Acute psychosis after anesthesia: the case for antibiomania. 2005 Paediatr Anaesth pmid:16029408
Korppi M Community-acquired pneumonia in children: issues in optimizing antibacterial treatment. 2003 Paediatr Drugs pmid:14658923
Capitano B et al. Antibacterials for the prophylaxis and treatment of bacterial endocarditis in children. 2001 Paediatr Drugs pmid:11706922
Zar HJ Neonatal chlamydial infections: prevention and treatment. 2005 Paediatr Drugs pmid:15871630
Shinkai M and Rubin BK Macrolides and airway inflammation in children. 2005 Paediatr Respir Rev pmid:16153572
Wood N and McIntyre P Pertussis: review of epidemiology, diagnosis, management and prevention. 2008 Paediatr Respir Rev pmid:18694712
Faraji F et al. The effect of Helicobacter pylori eradication on migraine: a randomized, double blind, controlled trial. 2012 Nov-Dec Pain Physician pmid:23159967
Khan MK et al. Bioequivalence study of two oral formulations of clarithromycin in human male subjects. 2011 Pak J Pharm Sci pmid:21190917
Fagoonee S et al. Efficacy of cefixime-based triple therapy for Helicobacter pylori eradication: a retrospective study. 2013 Panminerva Med pmid:24088806
Cisarò F et al. Ranitidine bismuth citrate in the first-line of Helicobacter pylori treatment. 2011 Panminerva Med pmid:21659979
Ribaldone DG et al. Efficacy of amoxycillin and clarithromycin-based triple therapy for Helicobacter pylori eradication: a 10-year trend in Turin, Italy. 2015 Panminerva Med pmid:25971330
Tursi A et al. Evaluation of the efficacy and tolerability of four different therapeutic regimens for the Helicobacter pylori eradication. 1996 Panminerva Med pmid:9009677
Barbon V On the efficacy of macrolide-based therapy for Helicobacter pylori infection. 2009 Panminerva Med pmid:19352310
Palmas F et al. Eradication of Helicobacter pylori infection with proton pump inhibitor-based triple therapy. A randomised study. 2002 Panminerva Med pmid:12032434
Tursi A et al. Decreasing efficacy of the standard seven-day triple therapy containing amoxycillin and clarithromycin in curing Helicobacter pylori infection in clinical setting in Italy: a 10-year follow-up study. 2014 Panminerva Med pmid:24637473
Hemphill A et al. Treatment of echinococcosis: albendazole and mebendazole--what else? 2014 Parasite pmid:25526545
Tripathi R et al. Clarithromycin, a cytochrome P450 inhibitor, can reverse mefloquine resistance in Plasmodium yoelii nigeriensis- infected Swiss mice. 2011 Parasitology pmid:21756423
Pandey SK et al. Antimalarial interaction of quinine and quinidine with clarithromycin. 2013 Parasitology pmid:23137860
Masuda H et al. Characteristics and trends of clarithromycin-resistant Helicobacter pylori isolates in Japan over a decade. 2004 Pathobiology pmid:15051929
Rodríguez-Sevilla G et al. Influence of three-dimensional lung epithelial cells and interspecies interactions on antibiotic efficacy against Mycobacterium abscessus and Pseudomonas aeruginosa. 2018 Pathog Dis pmid:29648588
Ploy MC et al. [Antibacterial activity of clarithromycin and its hydroxylated derivative and two other macrolides against thirty strains of Streptococcus pneumoniae]. 1994 Pathol. Biol. pmid:7824300
Gevaudan MJ et al. [Evaluation of the extra- and intracellular activity of clarithromycin against Mycobacterium chelonae]. 1994 Pathol. Biol. pmid:7824305
Dauendorffer JN et al. In vitro sensitivity of Mycobacterium xenopi to five antibiotics. 2002 Pathol. Biol. pmid:12504367
Ximenes E et al. [Ciprofloxacin, clarithromycin, rifampin: in vitro bactericidal activity of double and triple drug combinations against strains of atypical mycobacteria]. 1993 Pathol. Biol. pmid:8233629
Dabernat H et al. [in vitro activity of telithromycin against Haemophilus influenzae]. 2002 Pathol. Biol. pmid:11873632
Heurtin C et al. [Comparative study of the bacteriostatic and bactericidal activity of levofloxacin against Pasteurella strains isolated from man]. 2001 Pathol. Biol. pmid:11692747
Mariani-Kurkdjian P et al. [Emergence of macrolide resistant Streptococcus pyogenes strains in pediatric patients in France]. 2004 Pathol. Biol. pmid:15465270
Géhanno P et al. [Clarithromycin versus amoxicillin-clavulanic acid in the treatment of acute maxillary sinusitis in adults]. 1996 Pathol. Biol. pmid:8763594
Tankovic J et al. Clarithromycin resistance of Helicobacter pylori has a major impact on the efficacy of the omeprazole-amoxicillin-clarithromycin therapy. 2001 Pathol. Biol. pmid:11642014
Okiyama Y et al. Helicobacter heilmannii infection: clinical, endoscopic and histopathological features in Japanese patients. 2005 Pathol. Int. pmid:15982214
Chang WJ et al. Successful salvage treatment of steroid-refractory bronchiolar COP with low-dose macrolides. 2012 Pathol. Int. pmid:22243785
Suzuki T et al. Localization of antigen-presenting cells in Helicobacter pylori-infected gastric mucosa. 2002 Pathol. Int. pmid:12031081
Schulz S et al. Molecular diagnosis of a Mycobacterium chelonae infection. 2001 Pathol. Res. Pract. pmid:11261816
Grove DI and Koutsouridis G Increasing resistance of Helicobacter pylori to clarithromycin: is the horse bolting? 2002 Pathology pmid:11902451
Grove DI et al. Comparison of culture, histopathology and urease testing for the diagnosis of Helicobacter pylori gastritis and susceptibility to amoxycillin, clarithromycin, metronidazole and tetracycline. 1998 Pathology pmid:9643503
Midolo PD et al. Antimicrobial resistance testing of Helicobacter pylori: a comparison of Etest and disk diffusion methods. 1997 Pathology pmid:9423225
McLean S and Sheikh A Effectiveness, tolerability and safety of azithromycin 1% in DuraSite for acute bacterial conjunctivitis. 2010 Patient Prefer Adherence pmid:20517467
Zhang XR et al. Pharmacokinetics of clarithromycin citrate salt after oral administration to beagle dogs and food effects on its absorption. 2008 Nov-Dec PDA J Pharm Sci Technol pmid:19634347
Koutsoubari I et al. Effect of clarithromycin on acute asthma exacerbations in children: an open randomized study. 2012 Pediatr Allergy Immunol pmid:22433020
Akelma AZ et al. Clarithromycin in treatment of acute asthma exacerbations: principles of appropriate antibiotic use. 2012 Pediatr Allergy Immunol pmid:22984834
Novembre E et al. Systemic treatment of rhinosinusitis in children. 2007 Pediatr Allergy Immunol pmid:17767611
Andrianov M et al. A 15-year-old boy with abdominal pain, growth retardation, and anemia secondary to Helicobacter pylori-associated peptic ulcer. 2015 Pediatr Ann pmid:25806733
Russo G et al. Effect of eradication of Helicobacter pylori in children with chronic immune thrombocytopenia: a prospective, controlled, multicenter study. 2011 Pediatr Blood Cancer pmid:20830773
van Doorn HR et al. Widened coronary arteries in a feverish child. 2006 Jul-Aug Pediatr Cardiol pmid:16830076
Mytinger JR et al. Henoch-Schönlein purpura associated with Helicobacter pylori infection in a child. 2008 Nov-Dec Pediatr Dermatol pmid:19067870
Nanda S et al. Multidrug-resistant cutaneous tuberculosis: response to therapy. 2003 Nov-Dec Pediatr Dermatol pmid:14651584
Martire B et al. Persistent B-cell lymphopenia, multiorgan disease, and erythema multiforme caused by Mycoplasma pneumoniae infection. 2005 Nov-Dec Pediatr Dermatol pmid:16354262
Bilgili SG et al. Phototoxic dermatitis due to Chenopodium album in a child. 2011 Nov-Dec Pediatr Dermatol pmid:21854411
Lindeboom JA Facial Skin Lesions in Children Caused by Nontuberculous Mycobacteria. Pediatr Dermatol pmid:26823205
Brantley JS et al. Cutaneous Infection with Mycobacterium abscessus in a child. 2006 Mar-Apr Pediatr Dermatol pmid:16650219
Jang HS et al. Successful treatment of localized cutaneous infection caused by Mycobacterium scrofulaceum with clarithromycin. 2005 Sep-Oct Pediatr Dermatol pmid:16191006
Kurekci AE et al. Complete platelet recovery after treatment of Helicobacter pylori infection in a child with chronic immune thrombocytopenic purpura: a case report. 2004 Oct-Nov Pediatr Hematol Oncol pmid:15626015
Bay A et al. Helicobacter pylori infection-related pancytopenia in a young boy. 2011 Pediatr Hematol Oncol pmid:21728722
Hayashi H et al. Helicobacter pylori infection in children with chronic idiopathic thrombocytopenic purpura. 2005 Pediatr Int pmid:15910453
Ciftçi E et al. Investigation of risk factors for tonsillopharyngitis with macrolide resistant Streptococcus pyogenes in Turkish children. 2002 Pediatr Int pmid:12421263
Kato S and Fujimura S Primary antimicrobial resistance of Helicobacter pylori in children during the past 9 years. 2010 Pediatr Int pmid:19563459
Suzuki R et al. Sinobronchial syndrome treated as intractable asthma. 2018 Pediatr Int pmid:30320426
Okuda M et al. Nationwide survey of Helicobacter pylori treatment for children and adolescents in Japan. 2017 Pediatr Int pmid:27223686
Nishio N et al. Cat scratch disease with encephalopathy in a 9-year-old girl. 2008 Pediatr Int pmid:19067901
Defilippi AC et al. Changes in blood eosinophil numbers during Mycoplasma pneumoniae infection in wheezing and non-wheezing, atopic and non-atopic children. 2008 Pediatr Int pmid:19261132
Sasaoka Y et al. Neonatal apnea with Chlamydia pneumoniae infection. 2017 Pediatr Int pmid:28102626
Wiedermann BL Macrolides: clarithromycin and azithromycin. 1998 Pediatr Rev pmid:9654947
Woo MS et al. Pediatric transplant grand rounds. A case presentation: skin lesions in a post-lung transplant patient. 1997 Pediatr Transplant pmid:10084776
Kalman S et al. Mycoplasma pneumoniae infection in a child after renal transplantation. 2004 Pediatr Transplant pmid:15367286
Cohen M et al. Histologic findings in "ex- Helicobacter pylori" gastric biopsies of pediatric patients. 2005 Jul-Aug Pediatr. Dev. Pathol. pmid:16010501
von König CH Use of antibiotics in the prevention and treatment of pertussis. 2005 Pediatr. Infect. Dis. J. pmid:15876929
Syrogiannopoulos GA et al. High prevalence of erythromycin resistance of Streptococcus pyogenes in Greek children. 2001 Pediatr. Infect. Dis. J. pmid:11734765
Baughman AL and Bisgard KM Need for equivalence testing of efficacy of alternative antibiotics for treatment of pertussis. 2003 Pediatr. Infect. Dis. J. pmid:12586986
Petersen JP et al. Community outbreak of perianal group A streptococcal infection in Denmark. 2003 Pediatr. Infect. Dis. J. pmid:12586971
Block S et al. Mycoplasma pneumoniae and Chlamydia pneumoniae in pediatric community-acquired pneumonia: comparative efficacy and safety of clarithromycin vs. erythromycin ethylsuccinate. 1995 Pediatr. Infect. Dis. J. pmid:7667050
Lopes AI et al. Antibiotic-resistant Helicobacter pylori strains in Portuguese children. 2005 Pediatr. Infect. Dis. J. pmid:15876938
Nightingale CH Pharmacokinetics and pharmacodynamics of newer macrolides. 1997 Pediatr. Infect. Dis. J. pmid:9109156
Tarlow MJ et al. Future indications for macrolides. 1997 Pediatr. Infect. Dis. J. pmid:9109159
Green PA et al. Mycobacterium avium complex parotid lymphadenitis: successful therapy with clarithromycin and ethambutol. 1993 Pediatr. Infect. Dis. J. pmid:8346008
Syrogiannopoulos GA et al. Two dosages of clarithromycin for five days, amoxicillin/clavulanate for five days or penicillin V for ten days in acute group A streptococcal tonsillopharyngitis. 2004 Pediatr. Infect. Dis. J. pmid:15361727
Yang YJ et al. Prevalence and rapid identification of clarithromycin-resistant Helicobacter pylori isolates in children. 2001 Pediatr. Infect. Dis. J. pmid:11465837
Guay DR and Craft JC Overview of the pharmacology of clarithromycin suspension in children and a comparison with that in adults. 1993 Pediatr. Infect. Dis. J. pmid:8295810
Hebert AA et al. Comparative safety and efficacy of clarithromycin and cefadroxil suspensions in the treatment of mild to moderate skin and skin structure infections in children. 1993 Pediatr. Infect. Dis. J. pmid:8295811
Pukander JS et al. Clarithromycin vs. amoxicillin suspensions in the treatment of pediatric patients with acute otitis media. 1993 Pediatr. Infect. Dis. J. pmid:8295812
Still JG et al. Comparison of clarithromycin and penicillin VK suspensions in the treatment of children with streptococcal pharyngitis and review of currently available alternative antibiotic therapies. 1993 Pediatr. Infect. Dis. J. pmid:8295815
Craft JC and Siepman N Overview of the safety profile of clarithromycin suspension in pediatric patients. 1993 Pediatr. Infect. Dis. J. pmid:8295816
Klein JO Clarithromycin: where do we go from here? 1993 Pediatr. Infect. Dis. J. pmid:8295817
Hardy DJ Extent and spectrum of the antimicrobial activity of clarithromycin. 1993 Pediatr. Infect. Dis. J. pmid:8295818
Bradley JS et al. Comparative study of levofloxacin in the treatment of children with community-acquired pneumonia. 2007 Pediatr. Infect. Dis. J. pmid:17901791
Kuhn SM et al. Treatment of Mycobacterium marinum facial abscess using clarithromycin. 1995 Pediatr. Infect. Dis. J. pmid:7567299
Lederer J et al. Clarithromycin treatment of posttraumatic Mycobacterium fortuitum wound infection. 1993 Pediatr. Infect. Dis. J. pmid:8414785
Lebel MH and Mehra S Efficacy and safety of clarithromycin versus erythromycin for the treatment of pertussis: a prospective, randomized, single blind trial. 2001 Pediatr. Infect. Dis. J. pmid:11740322
Dierig A et al. Antibiotic treatment of pertussis: are 7 days really sufficient? 2015 Pediatr. Infect. Dis. J. pmid:25247586
Steele RW et al. Compliance issues related to the selection of antibiotic suspensions for children. 2001 Pediatr. Infect. Dis. J. pmid:11176558
Klein JO History of macrolide use in pediatrics. 1997 Pediatr. Infect. Dis. J. pmid:9109154
Klein JO Clarithromycin and azithromycin. 1998 Pediatr. Infect. Dis. J. pmid:9655546
Al Soub H et al. Myocardial abscess and bacteremia complicating Mycobacterium fortuitum pacemaker infection: case report and review of the literature. 2009 Pediatr. Infect. Dis. J. pmid:19859019
McCracken GH Microbiologic activity of the newer macrolide antibiotics. 1997 Pediatr. Infect. Dis. J. pmid:9109155
Ferguson PJ and Saulsbury FT Successful treatment of chronic Mycobacterium abscessus otitis media with clarithromycin. 1996 Pediatr. Infect. Dis. J. pmid:8866816
Freyne B and Curtis N Mycobacterium gordonae Skin Infection in an Immunocompetent Child. 2017 Pediatr. Infect. Dis. J. pmid:28403059
Shimizu T et al. Case of intrafamilial Helicobacter pylori reinfection after successful eradication therapy. 2000 Pediatr. Infect. Dis. J. pmid:11001123
Reid R et al. Pneumococcal meningitis during therapy of otitis media with clarithromycin. 1995 Pediatr. Infect. Dis. J. pmid:8786899
Mason EO et al. Macrolide resistance among middle ear isolates of Streptococcus pneumoniae observed at eight United States pediatric centers: prevalence of M and MLSB phenotypes. 2003 Pediatr. Infect. Dis. J. pmid:12867838
Lindeboom JA et al. Esthetic outcome of surgical excision versus antibiotic therapy for nontuberculous mycobacterial cervicofacial lymphadenitis in children. 2009 Pediatr. Infect. Dis. J. pmid:19773678