MeSH term | MeSH ID | Detail |
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Myxoma | D009232 | 1 associated lipids |
Kleine-Levin Syndrome | D017593 | 1 associated lipids |
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Vianna JS et al. | The interplay between mutations in cagA, 23S rRNA, gyrA and drug resistance in Helicobacter pylori. | 2018 | Rev. Inst. Med. Trop. Sao Paulo | pmid:29972462 |
Myojin S et al. | Chronic otitis media caused by Mycobacterium abscessus spp. massiliense treated with tigecycline in a 10-year-old child. | 2018 | Int. J. Infect. Dis. | pmid:29966711 |
Liou JM et al. | Efficacies of Genotypic Resistance-Guided vs Empirical Therapy for Refractory Helicobacter pylori Infection. | 2018 | Gastroenterology | pmid:29964036 |
Kwofie SK et al. | Screening of Isocitrate Lyase for Novel Anti-Buruli Ulcer Natural Products Originating from Africa. | 2018 | Molecules | pmid:29954088 |
Tanabe H et al. | Vonoprazan-based triple therapy is non-inferior to susceptibility-guided proton pump inhibitor-based triple therapy for Helicobacter pylori eradication. | 2018 | Ann. Clin. Microbiol. Antimicrob. | pmid:29950163 |
Sandri A et al. | Inhibition of Pseudomonas aeruginosa secreted virulence factors reduces lung inflammation in CF mice. | 2018 | Virulence | pmid:29938577 |
Gonzalez-Hormazabal P et al. | Prevalence of clarithromycin resistance in Helicobacter pylori in Santiago, Chile, estimated by real-time PCR directly from gastric mucosa. | 2018 | BMC Gastroenterol | pmid:29925321 |
Clarithromycin in patients with coronary artery disease. | 2018 | Med Lett Drugs Ther | pmid:29913468 | |
Fiorini G et al. | Pylera and sequential therapy for first-line Helicobacter pylori eradication: a culture-based study in real clinical practice. | 2018 | Eur J Gastroenterol Hepatol | pmid:29481383 |
Talarico S et al. | High prevalence of Helicobacter pylori clarithromycin resistance mutations among Seattle patients measured by droplet digital PCR. | 2018 | Helicobacter | pmid:29480566 |
Takemori N et al. | A novel combination of bortezomib, lenalidomide, and clarithromycin produced stringent complete response in refractory multiple myeloma complicated with diabetes mellitus - clinical significance and possible mechanisms: a case report. | 2018 | J Med Case Rep | pmid:29454372 |
Xu R et al. | Application of physiologically based pharmacokinetic modeling to the prediction of drug-drug and drug-disease interactions for rivaroxaban. | 2018 | Eur. J. Clin. Pharmacol. | pmid:29453492 |
Tsutsui A et al. | Trends and patterns of national antimicrobial consumption in Japan from 2004 to 2016. | 2018 | J. Infect. Chemother. | pmid:29428566 |
Zagari RM et al. | Treatment of Helicobacter pylori infection: A clinical practice update. | 2018 | Eur. J. Clin. Invest. | pmid:29144559 |
Liu DS et al. | Primary antibiotic resistance of Helicobacter pylori in Chinese patients: a multiregion prospective 7-year study. | 2018 | Clin. Microbiol. Infect. | pmid:29138101 |
Redondo JJ et al. | A novel RT-PCR for the detection of Helicobacter pylori and identification of clarithromycin resistance mediated by mutations in the 23S rRNA gene. | 2018 | Diagn. Microbiol. Infect. Dis. | pmid:29111147 |
Iwamoto J et al. | Effects of the Concomitant Use of Low-dose Clarithromycin with an Anti-TNFα Antibody in a Patient with Intestinal Behçet Disease. | 2018 | Intern. Med. | pmid:29093413 |
Inagaki Y et al. | Disseminated Cutaneous Infection of Mycobacterium colombiense in a Patient with Myelodysplastic Syndrome. | 2018 | Intern. Med. | pmid:29093379 |
Ullah S et al. | Hydrophilically modified self-assembling α-tocopherol derivative as niosomal nanocarrier for improving clarithromycin oral bioavailability. | 2018 | Artif Cells Nanomed Biotechnol | pmid:28541761 |
Cheung KS et al. | Long-term proton pump inhibitors and risk of gastric cancer development after treatment for : a population-based study. | 2018 | Gut | pmid:29089382 |