| MeSH term | MeSH ID | Detail |
|---|---|---|
| Myxoma | D009232 | 1 associated lipids |
| Kleine-Levin Syndrome | D017593 | 1 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- Clin. Infect. Dis. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Li Y et al. | Liposomal co-delivery of daptomycin and clarithromycin at an optimized ratio for treatment of methicillin-resistant Staphylococcus aureus infection. | 2015 | Drug Deliv | pmid:24471983 |
| Gunjan S et al. | Clarithromycin enhances the antimalarial efficacy of mefloquine via its increased bioavailability and disrupting P. falciparum apicoplast. | 2015 | Life Sci. | pmid:26164186 |
| Tongtawee T et al. | Effect of Pretreatment with Lactobacillus delbrueckii and Streptococcus thermophillus on Tailored Triple Therapy for Helicobacter pylori Eradication: A Prospective Randomized Controlled Clinical Trial. | 2015 | Asian Pac. J. Cancer Prev. | pmid:26163609 |
| Fujimura S et al. | Antimicrobial efficacy of combined clarithromycin plus daptomycin against biofilms-formed methicillin-resistant Staphylococcus aureus on titanium medical devices. | 2015 | J. Infect. Chemother. | pmid:26162777 |
| Cavkaytar S et al. | Clarithromycin regresses endometriotic implants in rat endometriosis model. | 2015 | J Obstet Gynaecol | pmid:26156575 |
| Bai P et al. | Susceptibility of Helicobacter pylori to antibiotics in Chinese patients. | 2015 | J Dig Dis | pmid:26147515 |
| Nie W et al. | Species Identification and Clarithromycin Susceptibility Testing of 278 Clinical Nontuberculosis Mycobacteria Isolates. | 2015 | Biomed Res Int | pmid:26146620 |
| Kozan G et al. | Effect of systemic clarithromycin and prednisolone on histamine-induced otitis media in guinea pigs. | 2015 | Acta Otolaryngol. | pmid:26143935 |
| Ferro BE et al. | Time-kill kinetics of slowly growing mycobacteria common in pulmonary disease. | 2015 | J. Antimicrob. Chemother. | pmid:26142475 |
| Honda M et al. | Preoperative vs Postoperative Eradication of Helicobacter pylori in 150 Patients with Gastric Cancer: A Randomized Controlled Trial. | 2015 | J. Am. Coll. Surg. | pmid:26141464 |
| Reveiz L and Cardona AF | Antibiotics for acute laryngitis in adults. | 2015 | Cochrane Database Syst Rev | pmid:26002823 |
| Ahmed S and Atia NN | Simultaneous determination of triple therapy for Helicobacter pylori in human plasma by reversed phase chromatography with online wavelength switching. | 2015 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:25459696 |
| Klain V and Timmerman L | Comment on The dangers of gastritis: a case of clarithromycin-associated brief psychotic episode. | 2015 | J. Nerv. Ment. Dis. | pmid:26034875 |
| Prapitpaiboon H et al. | High Efficacy of Levofloxacin-Dexlansoprazole-Based Quadruple Therapy as a First Line Treatment for Helicobacter pylori Eradication in Thailand. | 2015 | Asian Pac. J. Cancer Prev. | pmid:26028098 |
| Nayyar E and Taimur S | Sporotrichoid lesions: an age-old conundrum. | 2015 | Am. J. Med. | pmid:26021809 |
| Harb AH et al. | Systematic review and meta-analysis: full- vs. half-dose anti-microbials in clarithromycin-based regimens for Helicobacter pylori eradication. | 2015 | Aliment. Pharmacol. Ther. | pmid:26011564 |
| Rose SJ et al. | Mycobacterium avium Possesses Extracellular DNA that Contributes to Biofilm Formation, Structural Integrity, and Tolerance to Antibiotics. | 2015 | PLoS ONE | pmid:26010725 |
| Srivastava AK et al. | In Silico Profiling of the Potentiality of Curcumin and Conventional Drugs for CagA Oncoprotein Inactivation. | 2015 | Arch. Pharm. (Weinheim) | pmid:25996140 |
| Koh WJ et al. | Response to Switch from Intermittent Therapy to Daily Therapy for Refractory Nodular Bronchiectatic Mycobacterium avium Complex Lung Disease. | 2015 | Antimicrob. Agents Chemother. | pmid:25987622 |
| Heo J et al. | Concomitant and hybrid therapy for Helicobacter pylori infection: A randomized clinical trial. | 2015 | J. Gastroenterol. Hepatol. | pmid:25867608 |
| Sugita S et al. | EGFR-independent autophagy induction with gefitinib and enhancement of its cytotoxic effect by targeting autophagy with clarithromycin in non-small cell lung cancer cells. | 2015 | Biochem. Biophys. Res. Commun. | pmid:25858318 |
| Kesselheim AS et al. | Reductions in Use of Colchicine after FDA Enforcement of Market Exclusivity in a Commercially Insured Population. | 2015 | J Gen Intern Med | pmid:25855479 |
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| Zhang S et al. | Early or late antibiotic intervention prevents Helicobacter pylori-induced gastric cancer in a mouse model. | 2015 | Cancer Lett. | pmid:25853150 |
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| Burton AJ et al. | Activity of clarithromycin or rifampin alone or in combination against experimental Rhodococcus equi infection in mice. | 2015 | Antimicrob. Agents Chemother. | pmid:25824218 |
| Kazama I et al. | Macroscopic haemoglobinuria associated with Mycoplasma pneumoniae infection successfully treated by clarithromycin. | 2015 | Infez Med | pmid:25819056 |
| Silva JT et al. | Mycobacterium abscessus pulmonary infection complicated with vertebral osteomyelitis in a heart transplant recipient: case report and literature review. | 2015 | Transpl Infect Dis | pmid:25816889 |
| Sugawara M et al. | Exploration of a standard treatment for Buruli ulcer through a comprehensive analysis of all cases diagnosed in Japan. | 2015 | J. Dermatol. | pmid:25809502 |
| Iino Y et al. | Clinical effects of clarithromycin on persistent inflammation following Haemophilus influenzae-positive acute otitis media. | 2015 | Acta Otolaryngol. | pmid:25649881 |
| Streetman DS and Stout SM | Is there a clinically relevant interaction between clarithromycin and statins not metabolized by cytochrome P450 3A4? | 2015 | CMAJ | pmid:25646282 |
| Ang TL et al. | Ten-day triple therapy versus sequential therapy versus concomitant therapy as first-line treatment for Helicobacter pylori infection. | 2015 | J. Gastroenterol. Hepatol. | pmid:25639278 |
| Kimko H et al. | Helicobacter pylori treatment in children: defining a dose for rabeprazole as a part of a triple therapy regimen. | 2015 | J Clin Pharmacol | pmid:25639255 |
| Berry AC et al. | Not All Helicobacter Are pylori. | 2015 | Clin. Gastroenterol. Hepatol. | pmid:25638590 |
| Dinca EB et al. | The dangers of gastritis: a case of clarithromycin-associated brief psychotic episode. | 2015 | J. Nerv. Ment. Dis. | pmid:25629665 |
| Liu Q et al. | Efficacy of real-time PCR-based detection of Helicobacter pylori infection and genotypic resistance-guided quadruple therapy as the first-line treatment for functional dyspepsia with Helicobacter pylori infection. | 2015 | Eur J Gastroenterol Hepatol | pmid:25629566 |
| Genc G et al. | Does systemic clarithromycin therapy have an inhibitory effect on tympanosclerosis? An experimental animal study. | 2015 | J Laryngol Otol | pmid:25619629 |
| Galvidis I et al. | Group determination of 14-membered macrolide antibiotics and azithromycin using antibodies against common epitopes. | 2015 | Anal. Biochem. | pmid:25256165 |
| Siekmeier R et al. | Inhalation of macrolides: a novel approach to treatment of pulmonary infections. | 2015 | Adv. Exp. Med. Biol. | pmid:25252902 |
| Jiang F et al. | The influences of CYP2D6 genotypes and drug interactions on the pharmacokinetics of venlafaxine: exploring predictive biomarkers for treatment outcomes. | 2015 | Psychopharmacology (Berl.) | pmid:25510856 |
| Kim H et al. | Efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenia patients with moderate thrombocytopenia. | 2015 | Ann. Hematol. | pmid:25501820 |
| Phan TN et al. | High rate of levofloxacin resistance in a background of clarithromycin- and metronidazole-resistant Helicobacter pylori in Vietnam. | 2015 | Int. J. Antimicrob. Agents | pmid:25499186 |
| Adebisi AO et al. | Formulation and evaluation of floating mucoadhesive alginate beads for targeting Helicobacter pylori. | 2015 | J. Pharm. Pharmacol. | pmid:25496042 |
| Tsay FW et al. | Reverse sequential therapy achieves a similar eradication rate as standard sequential therapy for Helicobacter pylori eradication: a randomized controlled trial. | 2015 | Helicobacter | pmid:25495272 |
| Mourad-Baars PE et al. | Low antibiotic resistance of Helicobacter pylori in The Netherlands. | 2015 | Helicobacter | pmid:25495199 |
| Jesus FP et al. | In Vitro and In Vivo Antimicrobial Activities of Minocycline in Combination with Azithromycin, Clarithromycin, or Tigecycline against Pythium insidiosum. | 2015 | Antimicrob. Agents Chemother. | pmid:26459895 |
| Higuchi K et al. | Efficacy and safety of 1-week Helicobacter pylori eradication therapy and 7-week rebamipide treatment after endoscopic submucosal dissection of early gastric cancer in comparison with 8-week PPI standard treatment: a randomized, controlled, prospective, multicenter study. | 2015 | Gastric Cancer | pmid:25098924 |
| Chan CC et al. | Comparison of 10-day sequential therapy with 7-day standard triple therapy for Helicobacter pylori eradication in inactive peptic ulcer disease and the efficiency of sequential therapy in inactive peptic ulcer disease and non-ulcer dyspepsia. | 2015 | BMC Gastroenterol | pmid:26635102 |
| Hsu PI et al. | A Randomized Controlled Study Comparing Reverse Hybrid Therapy and Standard Triple Therapy for Helicobacter pylori Infection. | 2015 | Medicine (Baltimore) | pmid:26632893 |
| Basyigit S et al. | The impact of bismuth addition to sequential treatment on Helicobacter pylori eradication: A pilot study. | 2015 | Bosn J Basic Med Sci | pmid:26614852 |
| Shin SH et al. | Helicobacter pylori Eradication Prevents Metachronous Gastric Neoplasms after Endoscopic Resection of Gastric Dysplasia. | 2015 | PLoS ONE | pmid:26580072 |
| Rose WE et al. | Prevention of biofilm formation by methacrylate-based copolymer films loaded with rifampin, clarithromycin, doxycycline alone or in combination. | 2015 | Pharm. Res. | pmid:24934663 |
| Buch T and Andersen SE | [Combination therapy with fluconazole and other QTc-prolonging drugs increase the QTc interval]. | 2015 | Ugeskr. Laeg. | pmid:26471025 |
| Wu IT et al. | Five-year sequential changes in secondary antibiotic resistance of Helicobacter pylori in Taiwan. | 2015 | World J. Gastroenterol. | pmid:26457027 |
| Boyanova L et al. | Linezolid susceptibility in Helicobacter pylori, including strains with multidrug resistance. | 2015 | Int. J. Antimicrob. Agents | pmid:26453146 |
| Barni S et al. | Azithromycin is more allergenic than clarithromycin in children with suspected hypersensitivity reaction to macrolides. | 2015 | J Investig Allergol Clin Immunol | pmid:25997306 |
| Zhang W et al. | Bismuth, lansoprazole, amoxicillin and metronidazole or clarithromycin as first-line Helicobacter pylori therapy. | 2015 | Gut | pmid:26338726 |
| Fasciana T et al. | Resistance to clarithromycin and genotypes in Helicobacter pylori strains isolated in Sicily. | 2015 | J. Med. Microbiol. | pmid:26338221 |
| Curth HM et al. | Effects of Helicobacter pylori Eradication in Chronic Spontaneous Urticaria: Results from a Retrospective Cohort Study. | 2015 | Am J Clin Dermatol | pmid:26334425 |
| Zhu YC et al. | Rapid prediction of inducible clarithromycin resistance in Mycobacterium abscessus. | 2015 | Mol. Cell. Probes | pmid:26334290 |
| Georgopoulos SD et al. | Treatment of Helicobacter Pylori infection: optimization strategies in a high resistance era. | 2015 | Expert Opin Pharmacother | pmid:26330278 |
| Koide T et al. | Analysis of Distribution of Ingredients in Commercially Available Clarithromycin Tablets Using Near-Infrared Chemical Imaging with Principal Component Analysis and Partial Least Squares. | 2015 | Chem. Pharm. Bull. | pmid:26329859 |
| Nozawa K et al. | Effect of surfactants or a water soluble polymer on the crystal transition of clarithromycin during a wet granulation process. | 2015 | Int J Pharm | pmid:26325306 |
| Noh HM et al. | Eradication Rate by Duration of Third-line Rescue Therapy with Levofloxacin after Helicobacter pylori Treatment Failure in Clinical Practice. | 2016 | Korean J Gastroenterol | pmid:27871162 |
| Yazdanbakhsh AR et al. | Reduction of non-Betalactam Antibiotics COD by Combined Coagulation and Advanced Oxidation Processes. | 2016 | Water Environ. Res. | pmid:28661328 |
| Fan W et al. | An unusual case of folliculitis spinulosa decalvans. | 2016 | Cutis | pmid:27814407 |
| Sancak S et al. | Intestinal blood flow by Doppler ultrasound: the impact of clarithromycin treatment for feeding intolerance in preterm neonates. | 2016 | J. Matern. Fetal. Neonatal. Med. | pmid:26135789 |
| Uehara H et al. | Comparison of the Anti-angiogenic and Anti-inflammatory Effects of Two Antibiotics: Clarithromycin Versus Moxifloxacin. | 2016 | Curr. Eye Res. | pmid:26125497 |
| Ohe M et al. | A case of lupus nephritis treated with clarithromycin, tacrolimus, and glucocorticoids. | 2016 | Kaohsiung J. Med. Sci. | pmid:27638410 |
| Phaw NA and Tsai HH | Eosinophilic gastroenteritis: a challenge to diagnose and treat. | 2016 | BMJ Case Rep | pmid:27613263 |
| Cosme A et al. | Antimicrobial Susceptibility-Guided Therapy Versus Empirical Concomitant Therapy for Eradication of Helicobacter pylori in a Region with High Rate of Clarithromycin Resistance. | 2016 | Helicobacter | pmid:25982426 |
| Ozeki K et al. | Association of Hay Fever with the Failure of Helicobacter pylori Primary Eradication. | 2016 | Intern. Med. | pmid:27374672 |
| Campillo A et al. | [Cuadruple concomitant non-bismuth therapy vs. classical triple therapy as first line therapy for Helicobacter pylori infection]. | 2016 | Med Clin (Barc) | pmid:27374029 |
| Khashei R et al. | High rate of A2142G point mutation associated with clarithromycin resistance among Iranian Helicobacter pylori clinical isolates. | 2016 | APMIS | pmid:27357065 |
| Alarcón-Millán J et al. | Clarithromycin resistance and prevalence of Helicobacter pylori virulent genotypes in patients from Southern México with chronic gastritis. | 2016 | Infect. Genet. Evol. | pmid:27355861 |
| Khonche A et al. | Adjunctive Therapy with Curcumin for Peptic Ulcer: a Randomized Controlled Trial. | 2016 | Drug Res (Stuttg) | pmid:27351245 |
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| Mayor S | Short term increase in neuropsychiatric events is seen with H pylori treatment containing clarithromycin. | 2016 | BMJ | pmid:27143325 |
| Shokri-Shirvani J et al. | Letter: global emergence of Helicobacter pylori antibiotic resistance - unanswered questions. | 2016 | Aliment. Pharmacol. Ther. | pmid:27137738 |
| Wong AY et al. | Association Between Acute Neuropsychiatric Events and Helicobacter pylori Therapy Containing Clarithromycin. | 2016 | JAMA Intern Med | pmid:27136661 |
| Zollner-Schwetz I et al. | Primary resistance of Helicobacter pylori is still low in Southern Austria. | 2016 | Int. J. Med. Microbiol. | pmid:27134190 |
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| Wong IC | Author's reply to Blake. | 2016 | BMJ | pmid:26957514 |
| Todo K et al. | Severe Helicobacter pylori gastritis-related thrombocytopenia and iron deficiency anemia in an adolescent female. | 2016 | Ann. Hematol. | pmid:26957356 |
| Iyer G and Alexander GC | Editorialists' reply to Blake. | 2016 | BMJ | pmid:26957321 |
| Blake Z | Study provides insufficient evidence of a link between clarithromycin and myocardial infarction. | 2016 | BMJ | pmid:26955978 |
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| Jain SK et al. | Lectin-Conjugated Clarithromycin and Acetohydroxamic Acid-Loaded PLGA Nanoparticles: a Novel Approach for Effective Treatment of H. pylori. | 2016 | AAPS PharmSciTech | pmid:26566630 |
| Di Giulio M et al. | In vitro antimicrobial susceptibility of Helicobacter pylori to nine antibiotics currently used in Central Italy. | 2016 | Scand. J. Gastroenterol. | pmid:26554617 |
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| Chen CH et al. | Mycobacterium abscessus complex bacteremia due to prostatitis after prostate biopsy. | 2016 | Indian J Tuberc | pmid:27998503 |
| Gehlot V et al. | Low prevalence of clarithromycin-resistant Helicobacter pylori isolates with A2143G point mutation in the 23S rRNA gene in North India. | 2016 | J Glob Antimicrob Resist | pmid:27530837 |
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| Siddiqui TR et al. | Emerging trends of antimicrobial resistance in Helicobacter pylori isolates obtained from Pakistani patients: The need for consideration of amoxicillin and clarithromycin. | 2016 | J Pak Med Assoc | pmid:27339574 |
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