MeSH term | MeSH ID | Detail |
---|---|---|
Myxoma | D009232 | 1 associated lipids |
Kleine-Levin Syndrome | D017593 | 1 associated lipids |
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Yeh I et al. | Cutaneous mycobacterial spindle cell pseudotumor: a potential mimic of soft tissue neoplasms. | 2011 | Am J Dermatopathol | pmid:21712686 |
Song H et al. | Cutaneous nontuberculous mycobacterial infection: a clinicopathological study of 7 cases. | 2009 | Am J Dermatopathol | pmid:19384062 |
Lai J et al. | Epithelioid histiocytic infiltrate caused by Mycobacterium scrofulaceum infection: a potential mimic of various neoplastic entities. | 2013 | Am J Dermatopathol | pmid:22935892 |
Sketris IS et al. | Comparison of anti-infective drug use in elderly persons in Manitoba, Nova Scotia, and Saskatchewan, Canada: relationship to drug insurance reimbursement policies. | 2004 | Am J Geriatr Pharmacother | pmid:15555476 |
Hsu O et al. | Decreased plasma efavirenz concentrations in a patient receiving rifabutin. | 2010 | Am J Health Syst Pharm | pmid:20852162 |
Johnson TJ and Hedge DD | Esomeprazole: a clinical review. | 2002 | Am J Health Syst Pharm | pmid:12132559 |
Halpern MT et al. | Cost-effectiveness of gemifloxacin: results from the GLOBE study. | 2002 | Am J Health Syst Pharm | pmid:12132563 |
Chahine C et al. | Ultrashort regimen of lansoprazole-amoxicillin-azithromycin for eradicating Helicobacter pylori. | 2001 | Am J Health Syst Pharm | pmid:11596697 |
Henneman A and Thornby KA | Risk of hypotension with concomitant use of calcium-channel blockers and macrolide antibiotics. | 2012 | Am J Health Syst Pharm | pmid:22644980 |
Kaeser YA et al. | Severe hypotension and bradycardia associated with verapamil and clarithromycin. | 1998 | Am J Health Syst Pharm | pmid:9825040 |
Three new studies expand understanding of MAC therapy. | 1996 | Am J Health Syst Pharm | pmid:8899122 | |
Peloquin CA and Berning SE | Advice on treatment of Mycobacterium avium complex infection. | 1997 | Am J Health Syst Pharm | pmid:9161632 |
H. pylori treatment recognized by FDA. | 1996 | Am J Health Syst Pharm | pmid:8725200 | |
Sonnenberg A et al. | Antibiotic therapy of Helicobacter pylori infection reduces healthcare expenditures related to duodenal ulcer. | 1999 | Am J Manag Care | pmid:10345967 |
Lilley LL and Guanci R | A dangerous combination. | 1998 | Am J Nurs | pmid:9612423 |
Antibiotic gets FDA nod for MAC treatment. | 1994 | Am J Nurs | pmid:8304386 | |
Evans AK and Cunningham MJ | Atypical mycobacterial cervicofacial lymphadenitis in children: a disease as old as mankind, yet a persistent challenge. | 2005 Sep-Oct | Am J Otolaryngol | pmid:16137534 |
Hashisaki GT | Update on macrolide antibiotics. | 1995 May-Jun | Am J Otolaryngol | pmid:7661309 |
Einarson A et al. | A prospective controlled multicentre study of clarithromycin in pregnancy. | 1998 | Am J Perinatol | pmid:9890248 |
Jacoby EB and Porter KB | Helicobacter pylori infection and persistent hyperemesis gravidarum. | 1999 | Am J Perinatol | pmid:10355915 |
Abouesh A and Hobbs WR | Clarithromycin-induced mania. | 1998 | Am J Psychiatry | pmid:9812131 |
Brooks JO and Hoblyn JC | Secondary mania in older adults. | 2005 | Am J Psychiatry | pmid:16263839 |
Keicho N and Kudoh S | Diffuse panbronchiolitis: role of macrolides in therapy. | 2002 | Am J Respir Med | pmid:14720066 |
Darkes MJ and Perry CM | Clarithromycin extended-release tablet: a review of its use in the management of respiratory tract infections. | 2003 | Am J Respir Med | pmid:14720016 |
Tohnai A et al. | Clarithromycin suppresses proliferation of rat nasal epithelium exposed to endotoxin. | 1998 Nov-Dec | Am J Rhinol | pmid:9883303 |
Zeng M et al. | Comparison of efficacy of mometasone furoate versus clarithromycin in the treatment of chronic rhinosinusitis without nasal polyps in Chinese adults. | 2011 Nov-Dec | Am J Rhinol Allergy | pmid:22185725 |
Gupta AK and Moorman CT | Nocardia nova infection after primary anterior cruciate ligament reconstruction with tibialis anterior allograft. | 2010 | Am J Sports Med | pmid:20375367 |
Yang X et al. | Comparison Between Sequential Therapy and Modified Bismuth-Included Quadruple Therapy for Helicobacter pylori Eradication in Chinese Patients. | Am J Ther | pmid:25923229 | |
Feng L et al. | Sequential Therapy or Standard Triple Therapy for Helicobacter pylori Infection: An Updated Systematic Review. | Am J Ther | pmid:25569598 | |
McCarthy DM et al. | Impact of cotherapy with some proton pump inhibitors on medical claims among HMO patients already using other common drugs also cleared by cytochrome P450. | 2003 Sep-Oct | Am J Ther | pmid:12975717 |
Chang NL et al. | Clarithromycin-Induced Torsades de Pointes. | Am J Ther | pmid:25057773 | |
Kurowski K et al. | Clarithromycin-induced alterations in vaginal flora. | 2000 | Am J Ther | pmid:11317173 |
Alkim H et al. | Role of Bismuth in the Eradication of Helicobacter pylori. | Am J Ther | pmid:26808355 | |
Jacobson TA | Comparative pharmacokinetic interaction profiles of pravastatin, simvastatin, and atorvastatin when coadministered with cytochrome P450 inhibitors. | 2004 | Am. J. Cardiol. | pmid:15518608 |
Hsu CH et al. | The lesson of supplementary treatment with Chinese medicine on severe laboratory-confirmed SARS patients. | 2006 | Am. J. Chin. Med. | pmid:17163582 |
Wang YC et al. | In vitro activity of Impatiens balsamina L. against multiple antibiotic-resistant Helicobacter pylori. | 2009 | Am. J. Chin. Med. | pmid:19655409 |
Sauter C and Blum S | Regression of lung lesions in Hodgkin's disease by antibiotics: case report and hypothesis on the etiology of Hodgkin's disease. | 2003 | Am. J. Clin. Oncol. | pmid:12576932 |
Kapadia M et al. | Invasive Streptomyces infections: six cases and literature review. | 2007 | Am. J. Clin. Pathol. | pmid:17369139 |
Buchanan Keller K and Lemberg L | Torsade. | 2008 | Am. J. Crit. Care | pmid:18158394 |
Gisbert JP et al. | Response to article by Forné et al. | 1996 | Am. J. Gastroenterol. | pmid:8561132 |
Coelho LG et al. | Once-daily Helicobacter pylori treatment to family members of gastric cancer patients. | 2000 | Am. J. Gastroenterol. | pmid:10710099 |
Pilotto A et al. | In vitro activity of rifabutin against strains of Helicobacter pylori resistant to metronidazole and clarithromycin. | 2000 | Am. J. Gastroenterol. | pmid:10710100 |
Stack WA et al. | Safety and efficacy of rabeprazole in combination with four antibiotic regimens for the eradication of Helicobacter pylori in patients with chronic gastritis with or without peptic ulceration. | 1998 | Am. J. Gastroenterol. | pmid:9772054 |
Adamek RJ and Bethke TD | Cure of Helicobacter pylori infection and healing of duodenal ulcer: comparison of pantoprazole-based one-week modified triple therapy versus two-week dual therapy. The International Pantoprazole HP Study Group. | 1998 | Am. J. Gastroenterol. | pmid:9772056 |
Vakil N and Cutler A | Ten-day triple therapy with ranitidine bismuth citrate, amoxicillin, and clarithromycin in eradicating Helicobacter pylori. | 1999 | Am. J. Gastroenterol. | pmid:10235192 |
Kawasaki M et al. | Ménétrièr's disease associated with Helicobacter pylori infection: resolution of enlarged gastric folds and hypoproteinemia after antibacterial treatment. | 1997 | Am. J. Gastroenterol. | pmid:9382064 |
Adamek RJ et al. | Pantoprazole versus omeprazole in one-week low-dose triple therapy for curve of H. pylori infection. | 1997 | Am. J. Gastroenterol. | pmid:9382084 |
Vakil N and Fennerty MB | Cost-effectiveness of treatment regimens for the eradication of Helicobacter pylori in duodenal ulcer. | 1996 | Am. J. Gastroenterol. | pmid:8607487 |
Treiber G | The influence of drug dosage on Helicobacter pylori eradication: a cost-effectiveness analysis. | 1996 | Am. J. Gastroenterol. | pmid:8607488 |
Parasakthi N and Goh KL | Primary and acquired resistance to clarithromycin among Helicobacter pylori strains in Malaysia. | 1995 | Am. J. Gastroenterol. | pmid:7872306 |