clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Myxoma D009232 1 associated lipids
Kleine-Levin Syndrome D017593 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


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Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

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What genes are associated with clarithromycin?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Howden CW Treatment of Helicobacter pylori infection: is less more? 2000 J. Clin. Gastroenterol. pmid:10993423
Catalano F et al. Five-day triple therapy in Helicobacter pylori-positive duodenal ulcer: an eighteen-month follow-up. 2000 J. Clin. Gastroenterol. pmid:10993428
Testoni PA and Bagnolo F In dyspeptic patients without gastric phase III of the migrating motor complex, Helicobacter pylori eradication produces no short-term changes in interdigestive motility pattern. 2000 Scand. J. Gastroenterol. pmid:10994618
Mushiroda T et al. The involvement of flavin-containing monooxygenase but not CYP3A4 in metabolism of itopride hydrochloride, a gastroprokinetic agent: comparison with cisapride and mosapride citrate. 2000 Drug Metab. Dispos. pmid:10997945
Huang AH et al. Impact of Helicobacter pylori antimicrobial resistance on the outcome of 1-week lansoprazole-based triple therapy. 2000 J. Formos. Med. Assoc. pmid:11000734
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Bermejo F et al. [Effects of Helicobacter pylori eradication on the recurrence of gastric ulcer during a 12-month follow up]. 2000 Med Clin (Barc) pmid:11002456
Gisbert JP et al. Proton pump inhibitor, clarithromycin and either amoxycillin or nitroimidazole: a meta-analysis of eradication of Helicobacter pylori. 2000 Aliment. Pharmacol. Ther. pmid:11012477
Catalano F et al. Helicobacter pylori-positive duodenal ulcer: three-day antibiotic eradication regimen. 2000 Aliment. Pharmacol. Ther. pmid:11012478
Gomollón F et al. Third line treatment for Helicobacter pylori: a prospective, culture-guided study in peptic ulcer patients. 2000 Aliment. Pharmacol. Ther. pmid:11012479
Westphal JF Macrolide - induced clinically relevant drug interactions with cytochrome P-450A (CYP) 3A4: an update focused on clarithromycin, azithromycin and dirithromycin. 2000 Br J Clin Pharmacol pmid:11012550
Yanagihara K et al. Intrapulmonary concentrations of inflammatory cytokines in a mouse model of chronic respiratory infection caused by Pseudomonas aeruginosa. 2000 Clin. Exp. Immunol. pmid:11012620
Alter P et al. [Impediment of cellular immune response under treatment with ticlopidine in a patient with Staphylococcus aureus endocarditis]. 2000 Z Kardiol pmid:11013974
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Wolfe J et al. Mycobacterium branderi from both a hand infection and a case of pulmonary disease. 2000 J. Clin. Microbiol. pmid:11015432
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Kuper JI and D'Aprile M Drug-Drug interactions of clinical significance in the treatment of patients with Mycobacterium avium complex disease. 2000 Clin Pharmacokinet pmid:11020135
Cirioni O et al. Inhibition of growth of Pneumocystis carinii by lactoferrins alone and in combination with pyrimethamine, clarithromycin and minocycline. 2000 J. Antimicrob. Chemother. pmid:11020255
Alarcón T et al. Clarithromycin resistance stability in Helicobacter pylori: influence of the MIC and type of mutation in the 23S rRNA. 2000 J. Antimicrob. Chemother. pmid:11020260
Guyot A et al. Clarithromycin appears to be linked with Clostridium difficile-associated diarrhoea in the elderly. 2000 J. Antimicrob. Chemother. pmid:11020269
Cammarota G et al. Six-day therapy with ranitidine bismuth citrate plus low-dose clarithromycin and tinidazole to cure Helicobacter pylori infection. 2000 Jul-Aug Hepatogastroenterology pmid:11020908
Umegaki N et al. Clarithromycin-resistance and point mutations in the 23S rRNA gene in Helicobacter pylori isolates from Japan. 2000 J. Gastroenterol. Hepatol. pmid:11022832
Goh K et al. Efficacy of a 1-week pantoprazole triple therapy in eradicating Helicobacter pylori in Asian patients. 2000 J. Gastroenterol. Hepatol. pmid:11022833
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Rea TH Trials of daily, long-term minocycline and rifampin or clarithromycin and rifampin in the treatment of borderline lepromatous and lepromatous leprosy. 2000 Int. J. Lepr. Other Mycobact. Dis. pmid:11036492
McWhinney PH et al. Failure to produce detectable antibodies to Legionella pneumophila by an immunocompetent adult. 2000 J. Infect. pmid:11041710
Frank F et al. Helicobacter pylori infection in recurrent abdominal pain. 2000 J. Pediatr. Gastroenterol. Nutr. pmid:11045841
Kelley MA et al. Breakthrough pneumococcal bacteremia in patients being treated with azithromycin and clarithromycin. 2000 Clin. Infect. Dis. pmid:11049784
Giannini E et al. Influence of Helicobacter pylori eradication therapy on 13C aminopyrine breath test: comparison among omeprazole-, lansoprazole-, or pantoprazole-containing regimens. 2000 Am. J. Gastroenterol. pmid:11051345
Bhasin DK et al. Drug resistance in Helicobacter pylori infection. 2000 Indian J Gastroenterol pmid:11060974
Edlund C et al. Pharmacokinetics and comparative effects of telithromycin (HMR 3647) and clarithromycin on the oropharyngeal and intestinal microflora. 2000 J. Antimicrob. Chemother. pmid:11062193
Seppälä K et al. Cure of Helicobacter pylori infection after failed primary treatment: one-center results from 120 patients. 2000 Scand. J. Gastroenterol. pmid:11063151
Chow LW et al. Clarithromycin attenuates mastectomy-induced acute inflammatory response. 2000 Clin. Diagn. Lab. Immunol. pmid:11063500
Herr H and You CH Relationship between Helicobacter pylori and rosacea: it may be a myth. 2000 J. Korean Med. Sci. pmid:11068993
Wong BC et al. Triple therapy with clarithromycin, omeprazole, and amoxicillin for eradication of Helicobacter pylori in duodenal ulcer patients in Asia and Africa. 2000 Aliment. Pharmacol. Ther. pmid:11069326
Dunne M et al. A randomized, double-blind trial comparing azithromycin and clarithromycin in the treatment of disseminated Mycobacterium avium infection in patients with human immunodeficiency virus. 2000 Clin. Infect. Dis. pmid:11073759
Delgado M et al. [Cavitating pneumonia in a patient infected with human immunodeficiency virus]. 2000 Jun-Jul Enferm. Infecc. Microbiol. Clin. pmid:11075487
Krebs T et al. Mycobacterium genavense infection in a patient with long-standing chronic lymphocytic leukaemia. 2000 J. Intern. Med. pmid:11086646
Ferrero M et al. Factors affecting the variation in antibiotic resistance of Helicobacter pylori over a 3-year period. 2000 Int. J. Antimicrob. Agents pmid:11091043
Yoshida H et al. Reversal of intra-amniotic Chlamydia trachomatis antigen status. 2000 Gynecol. Obstet. Invest. pmid:11093054
Knower MT et al. Clarithromycin for safe and cost-effective reduction of cyclosporine doses in lung allograft recipients. 2000 South. Med. J. pmid:11095559
Lucas J et al. Mycobacterium genavense infection in two aged ferrets with conjunctival lesions. 2000 Aust. Vet. J. pmid:11098383
Witthaut J and Möhlen S [Chronic paronychia and synovialitis of extensor tendons due to Mycobacterium marinum. Is diagnosis or treatment the problem?]. 2000 Handchir Mikrochir Plast Chir pmid:11103693
Lerro P et al. CagA seropositivity and the severity of Helicobacter pylori infection in dyspeptic children. 2000 Acta Paediatr. pmid:11106041
Fock KM Clarithromycin resistance in Helicobacter pylori infection: does it matter? 2000 J. Gastroenterol. Hepatol. pmid:11106085
Hamada H et al. [A case of pneumonia caused by Mycobacterium avium complex successfully treated with clarithromycin]. 2000 Nihon Ronen Igakkai Zasshi pmid:11109848
Warner A Clarithromycin--a precipitant for acute psychotic stress. 2000 Nov-Dec Psychosomatics pmid:11110120
Hunt RH et al. Implications of antibiotic resistance in the management of Helicobacter pylori infection: Canadian Helicobacter Study Group. 2000 Can. J. Gastroenterol. pmid:11111109