clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Myxoma D009232 1 associated lipids
Kleine-Levin Syndrome D017593 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


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Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

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What genes are associated with clarithromycin?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Barth J and Hahne W Review article: rabeprazole-based therapy in Helicobacter pylori eradication. 2002 Aliment. Pharmacol. Ther. pmid:11849125
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Sharara AI et al. Prevalence of Helicobacter pylori resistance to metronidazole, clarithromycin, amoxycillin and tetracycline in Lebanon. 2002 Int. J. Antimicrob. Agents pmid:11850169
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Choi IJ et al. Efficacy of low-dose clarithromycin triple therapy and tinidazole-containing triple therapy for Helicobacter pylori eradication. 2002 Aliment. Pharmacol. Ther. pmid:11856089
Bazzoli F et al. Low-dose lansoprazole and clarithromycin plus metronidazole vs. full-dose lansoprazole and clarithromycin plus amoxicillin for eradication of Helicobacter pylori infection. 2002 Aliment. Pharmacol. Ther. pmid:11856090
Rhomberg PR and Jones RN In vitro activity of 11 antimicrobial agents, including gatifloxacin and GAR936, tested against clinical isolates of Mycobacterium marinum. 2002 Diagn. Microbiol. Infect. Dis. pmid:11858912
Malfertheiner P et al. Current concepts in the management of Helicobacter pylori infection--the Maastricht 2-2000 Consensus Report. 2002 Aliment. Pharmacol. Ther. pmid:11860399
Kim JS et al. Effect of Helicobacter pylori eradication on duodenal ulcer scar in patients with no clinical history of duodenal ulcer. 2002 Aliment. Pharmacol. Ther. pmid:11860410
Poon SK et al. Primary resistance to antibiotics and its clinical impact on the efficacy of Helicobacter pylori lansoprazole-based triple therapies. 2002 Aliment. Pharmacol. Ther. pmid:11860412
Peitz U et al. High rate of post-therapeutic resistance after failure of macrolide-nitroimidazole triple therapy to cure Helicobacter pylori infection: impact of two second-line therapies in a randomized study. 2002 Aliment. Pharmacol. Ther. pmid:11860415
Masiá M et al. Fulminant hepatitis and fatal toxic epidermal necrolysis (Lyell disease) coincident with clarithromycin administration in an alcoholic patient receiving disulfiram therapy. 2002 Arch. Intern. Med. pmid:11863483
Lim JA et al. Prevalence of resistance to macrolide, lincosamide and streptogramin antibiotics in Gram-positive cocci isolated in a Korean hospital. 2002 J. Antimicrob. Chemother. pmid:11864949
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Levy M et al. Conservative treatment of primary gastric low-grade B-cell lymphoma of mucosa-associated lymphoid tissue: predictive factors of response and outcome. 2002 Am. J. Gastroenterol. pmid:11866264
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Kumar D et al. Pre and post eradication gastric inflammation in Helicobacter pylori-associated duodenal ulcer. 2002 Jan-Feb Indian J Gastroenterol pmid:11871846
Colebunders R and Florence E Neuropsychiatric reaction induced by clarithromycin. 2002 Sex Transm Infect pmid:11872875
Khan J and Javed M The incidence of non ulcer dyspepsia and its response to treatment. 2001 Oct-Dec J Ayub Med Coll Abbottabad pmid:11873428
Dabernat H et al. [in vitro activity of telithromycin against Haemophilus influenzae]. 2002 Pathol. Biol. pmid:11873632
Di Caro S et al. Mono, dual and triple moxifloxacin-based therapies for Helicobacter pylori eradication. 2002 Aliment. Pharmacol. Ther. pmid:11876707
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Georgopoulos SD et al. Effectiveness of two quadruple, tetracycline- or clarithromycin-containing, second-line, Helicobacter pylori eradication therapies. 2002 Aliment. Pharmacol. Ther. pmid:11876712
Elizalde JI et al. Influence of Helicobacter pylori infection and eradication on blood lipids and fibrinogen. 2002 Aliment. Pharmacol. Ther. pmid:11876713
Okada S et al. Angiocentric immunoproliferative lesions of the lung associated with diffuse renal involvement. 2002 Am. J. Kidney Dis. pmid:11877592
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Ecclissato C et al. Increased primary resistance to recommended antibiotics negatively affects Helicobacter pylori eradication. 2002 Helicobacter pmid:11886474
van Rooyen GF et al. Sensitive liquid chromatography-tandem mass spectrometry method for the determination of clarithromycin in human plasma. 2002 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:11890168
Murata Y et al. [Study on the detection methods of Helicobacter pylori from clinical specimens]. 2002 Rinsho Biseibutshu Jinsoku Shindan Kenkyukai Shi pmid:11895427
Klein JL et al. Prosthetic valve endocarditis caused by Bartonella quintana. 2002 Emerging Infect. Dis. pmid:11897074
Galarza M et al. Pediatric granulomatous cerebral amebiasis: a delayed diagnosis. 2002 Pediatr. Neurol. pmid:11897483
Ménard A et al. PCR-restriction fragment length polymorphism can also detect point mutation A2142C in the 23S rRNA gene, associated with Helicobacter pylori resistance to clarithromycin. 2002 Antimicrob. Agents Chemother. pmid:11897613
Grove DI and Koutsouridis G Increasing resistance of Helicobacter pylori to clarithromycin: is the horse bolting? 2002 Pathology pmid:11902451
Kornacker M et al. Occurrence of sarcoidosis subsequent to chemotherapy for non-Hodgkin's lymphoma: report of two cases. 2002 Ann. Hematol. pmid:11907791
McNulty C et al. Helicobacter pylori susceptibility testing by disc diffusion. 2002 J. Antimicrob. Chemother. pmid:11909833
Thiermann S et al. Comparison of phenotypic and genotypic methods for the detection of clarithromycin resistance in Mycobacterium avium. 2002 J. Antimicrob. Chemother. pmid:11909844
Kalach N et al. [Acquisition of secondary resistance after failure of a first treatment of Helicobacter pylori infection in children]. 2002 Arch Pediatr pmid:11915493
Kawakami E et al. Triple therapy with clarithromycin, amoxicillin and omeprazole for Helicobacter pylori eradication in children and adolescents. 2001 Jul-Sep Arq Gastroenterol pmid:11917721
Odaka T et al. Evaluation of the Helicobacter pylori stool antigen test for monitoring eradication therapy. 2002 Am. J. Gastroenterol. pmid:11922552
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Morimoto T et al. [Cost-effectiveness analysis of ambulatory treatment for adult patients with community-acquired pneumonia: according to Japanese Respiratory Society guidelines]. 2002 Nihon Kokyuki Gakkai Zasshi pmid:11925912
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Ciancio G et al. Regression of duodenal gastric metaplasia in Helicobacter pylori positive patients with duodenal ulcer disease. 2002 Dig Liver Dis pmid:11926569
Borody TJ et al. Treatment of severe Crohn's disease using antimycobacterial triple therapy--approaching a cure? 2002 Dig Liver Dis pmid:11926571
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Sinisalo J et al. Effect of 3 months of antimicrobial treatment with clarithromycin in acute non-q-wave coronary syndrome. 2002 Circulation pmid:11927522
Pilotto A and Malfertheiner P Review article: an approach to Helicobacter pylori infection in the elderly. 2002 Aliment. Pharmacol. Ther. pmid:11929385
Wong WM et al. One-week omeprazole, furazolidone and amoxicillin rescue therapy after failure of Helicobacter pylori eradication with standard triple therapies. 2002 Aliment. Pharmacol. Ther. pmid:11929398
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Nakamura T [The outline of medical treatment of peptic ulcer]. 2002 Nippon Rinsho pmid:11979808
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Kato M et al. [Guidelines for the management of Helicobacter pylori infection in Japan]. 2002 Nippon Rinsho pmid:11979813
Kato S [Guidelines of Helicobacter pylori eradication in children]. 2002 Nippon Rinsho pmid:11979815
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Fu HY et al. [Dual therapy for Helicobacter pylori resistance to anti microbial agents]. 2002 Nippon Rinsho pmid:11979819
Ohkusa T and Sato N [Proton pump inhibitor-based quadruple therapy regimen for Helicobacter pylori infection]. 2002 Nippon Rinsho pmid:11979821
Nagahara A et al. [Effect of PPI/AM re-treatment regimen for the patients with Helicobacter pylori infection after failure of first line eradication therapy by PPI/AC regimens]. 2002 Nippon Rinsho pmid:11979822
Shirai N and Furuta T [High dose dual PPI/AMPC therapy for the treatment of Helicobacter pylori infection after failure of usual standard triple PPI/AMPC/CAM therapy: CYP2C19 polymorphism]. 2002 Nippon Rinsho pmid:11979823
Tokunaga K and Takahashi S [Second line treatment regimen of PPI + AMPC + MNZ for patients with clarithromycin-resistant Helicobacter pylori infection]. 2002 Nippon Rinsho pmid:11979824
Sato R et al. [Minocycline-containing eradication therapy for patients with clarithromycin-resistant Helicobacter pylori infection]. 2002 Nippon Rinsho pmid:11979825
Mitsuno Y and Yoshida H [Triple therapy with faropenem, proton pump inhibitor (PPI), and amoxicillin for clarithromycin-resistant H. pylori eradication]. 2002 Nippon Rinsho pmid:11979826
Kagaya H et al. [Ecabet sodium (ECA) + PPI + AMPC therapy for clarithromycin-resistant Helicobacter pylori infections]. 2002 Nippon Rinsho pmid:11979827
Inoue K and Sugano K [Eradication therapy for clarithromycin-resistant and metronidazole-resistant Helicobacter pylori infection]. 2002 Nippon Rinsho pmid:11979828
Miwa H et al. [Adverse effects of H. pylori eradication therapy and its measure]. 2002 Nippon Rinsho pmid:11979829
Sakaki N [Acute mucosal lesion of the upper-gastrointestinal tract observed after H. pylori-eradication]. 2002 Nippon Rinsho pmid:11979830
Haruma K et al. [H. pylori eradication therapy and natural history of peptic ulcer]. 2002 Nippon Rinsho pmid:11979833