MeSH term | MeSH ID | Detail |
---|---|---|
Myxoma | D009232 | 1 associated lipids |
Kleine-Levin Syndrome | D017593 | 1 associated lipids |
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Gui J et al. | [Drug sensitivity analysis of Mycobacterium chelonae and Mycobacterium abscessus and evaluation of Etest for susceptibility testing]. | 2013 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:24252731 |
AvÅŸar E et al. | A multicenter, randomized, prospective study of 14-day ranitidine bismuth citrate- vs. lansoprazole-based triple therapy for the eradication of Helicobacter pylori in dyspeptic patients. | 2013 | Turk J Gastroenterol | pmid:24254262 |
Smiley R et al. | Comparative proteomics analysis of sarcosine insoluble outer membrane proteins from clarithromycin resistant and sensitive strains of Helicobacter pylori. | 2013 | J. Microbiol. | pmid:24173641 |
Morgan DR et al. | Risk of recurrent Helicobacter pylori infection 1 year after initial eradication therapy in 7 Latin American communities. | 2013 | JAMA | pmid:23403682 |
Naserpour Farivar T et al. | Prevalence of clarithromycin-resistant Helicobacter pylori in patients with chronic tonsillitis by allele-specific Scorpion real-time polymerase chain reaction assay. | 2013 | Laryngoscope | pmid:23404672 |
Koh WJ et al. | Treatment of refractory Mycobacterium avium complex lung disease with a moxifloxacin-containing regimen. | 2013 | Antimicrob. Agents Chemother. | pmid:23478956 |
Ohe M and Hashino S | Successful treatment of recurrent follicular B-cell lymphoma with clarithromycin, prednisolone, and cyclophosphamide. | 2013 | Korean J. Intern. Med. | pmid:23682236 |
Sadeghifard N et al. | Survey in Iran of clarithromycin resistance in Helicobacter pylori isolates by PCR-RFLP. | 2013 | Southeast Asian J. Trop. Med. Public Health | pmid:23682442 |
Togami K et al. | Subcellular distribution of azithromycin and clarithromycin in rat alveolar macrophages (NR8383) in vitro. | 2013 | Biol. Pharm. Bull. | pmid:23995662 |
Liu X et al. | Clarithromycin-loaded liposomes offering high drug loading and less irritation. | 2013 | Int J Pharm | pmid:23337631 |
Kim MS et al. | Long-term follow-up Helicobacter pylori reinfection rate and its associated factors in Korea. | 2013 | Helicobacter | pmid:23066652 |
Markert C et al. | Interaction of ambrisentan with clarithromycin and its modulation by polymorphic SLCO1B1. | 2013 | Eur. J. Clin. Pharmacol. | pmid:23748747 |
Faraji F et al. | The effect of Helicobacter pylori eradication on migraine: a randomized, double blind, controlled trial. | 2012 Nov-Dec | Pain Physician | pmid:23159967 |
Eremenko AA et al. | [Effect of clarithromycin on the systemic inflammatory response syndrome severity in patients after myocardial revascularization surgery]. | 2012 May-Jun | Anesteziol Reanimatol | pmid:22993930 |
Singh V et al. | Vesicular palmoplantar pityriasis rosea. | 2012 Mar-Apr | Skinmed | pmid:22545332 |
Gutiérrez-Castrellón P et al. | Efficacy and safety of clarithromycin in pediatric patients with upper respiratory infections: a systematic review with meta-analysis. | 2012 Mar-Apr | Rev. Invest. Clin. | pmid:22991774 |
Rajendiran S et al. | Increased protein carbonylation and decreased antioxidant status in anemic H. pylori infected patients: effect of treatment. | 2012 Jul-Aug | Saudi J Gastroenterol | pmid:22824768 |
De Sanctis V et al. | Anti-Helicobacter pylori therapy in primary MALT lymphoma of rectum. | 2012 Jul-Aug | Tumori | pmid:23052174 |
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de Lalibera IB et al. | Meningoencephalitis associated with Mycoplasma pneumoniae. | 2012 Jan-Mar | Einstein (Sao Paulo) | pmid:23045836 |
Dhillon GS et al. | Clarithromycin for prevention of bronchiolitis obliterans syndrome in lung allograft recipients. | 2012 Jan-Feb | Clin Transplant | pmid:21352378 |
Onsun N et al. | Impact of Helicobacter pylori infection on severity of psoriasis and response to treatment. | 2012 Jan-Feb | Eur J Dermatol | pmid:22063790 |
Montero-Tinnirello J et al. | [Pulmonary hemorrhage due to leptospirosis]. | 2012 Jan-Feb | Med Intensiva | pmid:21592620 |
Dai WQ et al. | The eradicating Helicobacter pylori infection in duodenal ulcer patients by three short-term triple therapies in China: a multicenter clinical comparative study. | 2012 Jan-Feb | Hepatogastroenterology | pmid:22260837 |
Shojaei H et al. | Chronic pulmonary disease due to Mycobacterium monacense infection: the first case from Iran. | 2012 | Ann Lab Med | pmid:22259785 |
Kim SY et al. | Pulmonary infection caused by Mycobacterium conceptionense. | 2012 | Emerging Infect. Dis. | pmid:22257692 |
Malfertheiner P et al. | Management of Helicobacter pylori infection--the Maastricht IV/ Florence Consensus Report. | 2012 | Gut | pmid:22491499 |
Seddon G et al. | Drug design for ever, from hype to hope. | 2012 | J. Comput. Aided Mol. Des. | pmid:22252446 |
Huang YK et al. | Lansoprazole-based sequential and concomitant therapy for the first-line Helicobacter pylori eradication. | 2012 | J Dig Dis | pmid:22435509 |
Choi SJ et al. | The prevalence of vaginal microorganisms in pregnant women with preterm labor and preterm birth. | 2012 | Ann Lab Med | pmid:22563554 |
Bowers JR et al. | Dominance of multidrug resistant CC271 clones in macrolide-resistant streptococcus pneumoniae in Arizona. | 2012 | BMC Microbiol. | pmid:22251616 |
Brož P et al. | Nonirritant intradermal skin test concentrations of ciprofloxacin, clarithromycin, and rifampicin. | 2012 | Allergy | pmid:22435670 |
Sharma H et al. | Fortuitous vasculitis. | 2012 | Ren Fail | pmid:22250755 |
Hojsak I et al. | Antibiotic resistance of Helicobacter pylori in pediatric patients -- 10 years' experience. | 2012 | Eur. J. Pediatr. | pmid:22430353 |
Koutsoubari I et al. | Effect of clarithromycin on acute asthma exacerbations in children: an open randomized study. | 2012 | Pediatr Allergy Immunol | pmid:22433020 |
Lin YH and Liu TC | Mycobacterium chelonae infection involving the auricle. | 2012 | QJM | pmid:21908384 |
Padovan J et al. | Investigating the barriers to bioavailability of macrolide antibiotics in the rat. | 2012 | Eur J Drug Metab Pharmacokinet | pmid:22113743 |
Ji R et al. | Mucosal barrier defects in gastric intestinal metaplasia: in vivo evaluation by confocal endomicroscopy. | 2012 | Gastrointest. Endosc. | pmid:22325805 |
Barberán J et al. | Update on the clinical utility and optimal use of cefditoren. | 2012 | Int J Gen Med | pmid:22675264 |
Kumar R et al. | Synthesis and antibacterial activity of a novel series of acylides active against community acquired respiratory pathogens. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22153939 |
Matsueda K et al. | A placebo-controlled trial of acotiamide for meal-related symptoms of functional dyspepsia. | 2012 | Gut | pmid:22157329 |
Togami K et al. | Aerosol-based efficient delivery of clarithromycin, a macrolide antimicrobial agent, to lung epithelial lining fluid and alveolar macrophages for treatment of respiratory infections. | 2012 | J Aerosol Med Pulm Drug Deliv | pmid:22360316 |
Shiotani A et al. | H. pylori eradication did not improve dysregulation of specific oncogenic miRNAs in intestinal metaplastic glands. | 2012 | J. Gastroenterol. | pmid:22382634 |
Ding FM et al. | Low-dose clarithromycin therapy modulates CD4(+) T-cell responses in a mouse model of chronic Pseudomonas aeruginosa lung infection. | 2012 | Respirology | pmid:22404374 |
Kadayifci A et al. | Low efficacy of clarithromycin including sequential regimens for Helicobacter pylori infection. | 2012 | Helicobacter | pmid:22404442 |
Gisbert JP and McNicholl AG | Maintenance of Helicobacter pylori eradication rates with triple therapy over 12 years in a Spanish hospital. | 2012 | Helicobacter | pmid:22404448 |
Salmon JH et al. | Discitis and sacroiliitis diagnosed 15 years after iatrogenic Mycobacterium xenopi inoculation. | 2012 | Joint Bone Spine | pmid:22405857 |
Alzolibani AA and Zedan K | Macrolides in chronic inflammatory skin disorders. | 2012 | Mediators Inflamm. | pmid:22685371 |
Masekela R and Green RJ | The role of macrolides in childhood non-cystic fibrosis-related bronchiectasis. | 2012 | Mediators Inflamm. | pmid:22570510 |
Konorev MR | [Use of the immunopotentiator N-acetyl-glucosamine-N-acetylmuramyl dipeptide during triple anti-Helicobacter pylori therapy]. | 2012 | Ter. Arkh. | pmid:23479993 |
Inamo Y et al. | A 7-year-old girl with subcutaneous emphysema, pneumomediastinum, pneumothorax, and pneumoretroperitoneum caused by Mycoplasma pneumoniae pneumonia. | 2012 | J. Infect. Chemother. | pmid:21901497 |
Lee MR et al. | CNS infections caused by Mycobacterium abscessus complex: clinical features and antimicrobial susceptibilities of isolates. | 2012 | J. Antimicrob. Chemother. | pmid:21980068 |
Cuadrado-LavÃn A et al. | Antimicrobial susceptibility of Helicobacter pylori to six antibiotics currently used in Spain. | 2012 | J. Antimicrob. Chemother. | pmid:21965436 |
Ivetic Tkalcevic V et al. | Cantharidin-induced inflammation in mouse ear model for translational research of novel anti-inflammatories. | 2012 | Transl Res | pmid:22677362 |
Ngan LT et al. | Growth-inhibiting, bactericidal, and urease inhibitory effects of Paeonia lactiflora root constituents and related compounds on antibiotic-susceptible and -resistant strains of Helicobacter pylori. | 2012 | J. Agric. Food Chem. | pmid:22891951 |
Kao SS et al. | 7-Day Nonbismuth-Containing Concomitant Therapy Achieves a High Eradication Rate for Helicobacter pylori in Taiwan. | 2012 | Gastroenterol Res Pract | pmid:22888337 |
Shah M et al. | Transient Psychotic Episode Induced by Helicobacter pylori Triple Therapy Treatment. | 2012 | Case Rep Gastroenterol | pmid:22855656 |
Heeb F et al. | Organic micropollutants in rivers downstream of the megacity Beijing: sources and mass fluxes in a large-scale wastewater irrigation system. | 2012 | Environ. Sci. Technol. | pmid:22845779 |
Wu W et al. | Recent Insights into Antibiotic Resistance in Helicobacter pylori Eradication. | 2012 | Gastroenterol Res Pract | pmid:22829809 |
Shih HY et al. | Comparison between Single-Dose Esomeprazole- and Pantoprazole-Based Triple Therapy on the Effectiveness for Helicobacter pylori Eradication in Taiwanese Population. | 2012 | Gastroenterol Res Pract | pmid:22829808 |
Choi GE et al. | Macrolide treatment for Mycobacterium abscessus and Mycobacterium massiliense infection and inducible resistance. | 2012 | Am. J. Respir. Crit. Care Med. | pmid:22878281 |
O'Connor MB et al. | Rituximab-induced pulmonary disease. | 2012 | Rheumatol. Int. | pmid:21892654 |
Nakagawa T et al. | [Multicenter study on clinical features and genetic characteristics of Mycobacterium avium strains from patients in Japan with lung disease caused by M. avium]. | 2012 | Kekkaku | pmid:23367826 |
Gochi M et al. | [Mycobacterium xenopi lung infection in a patient with multiple lung cysts that responded well to chemotherapy: a case report]. | 2012 | Kekkaku | pmid:23367833 |
Fujita M et al. | The clinical efficacy and safety of a fluoroquinolone-containing regimen for pulmonary MAC disease. | 2012 | J. Infect. Chemother. | pmid:21927844 |
Dobrick N et al. | [Legionnaires disease (legionella pneumonia)]. | 2012 | Praxis (Bern 1994) | pmid:23147600 |
Sano N et al. | Comprehensive Analysis of Bacterial Flora in Postoperative Maxillary Cyst Fluid by 16S rRNA Gene and Culture Methods. | 2012 | ISRN Dent | pmid:22685668 |
Lambiase A et al. | In vitro resistance to macrolides and clindamycin by Group B Streptococcus isolated from pregnant and nonpregnant women. | 2012 | Infect Dis Obstet Gynecol | pmid:22675244 |
Choi GE et al. | Activities of moxifloxacin in combination with macrolides against clinical isolates of Mycobacterium abscessus and Mycobacterium massiliense. | 2012 | Antimicrob. Agents Chemother. | pmid:22564831 |
Lu ZM et al. | Nucleosomes correlate with in vivo progression pattern of de novo methylation of p16 CpG islands in human gastric carcinogenesis. | 2012 | PLoS ONE | pmid:22558275 |
Raithatha AH and Bryden DC | Use of intravenous immunoglobulin therapy in the treatment of septic shock, in particular severe invasive group A streptococcal disease. | 2012 | Indian J Crit Care Med | pmid:22557832 |
Rudramurthy M et al. | Nasal vestibulitis due to Nocardiopsis dassonvillei in a diabetic patient. | 2012 | J. Med. Microbiol. | pmid:22556323 |
Talebi Bezmin Abadi A et al. | Primary resistance of Helicobacter pylori to levofloxacin and moxifloxacine in Iran. | 2012 | Intern Emerg Med | pmid:21437583 |
Ivetić TkalÄević V et al. | Topical azithromycin and clarithromycin inhibit acute and chronic skin inflammation in sensitized mice, with apparent selectivity for Th2-mediated processes in delayed-type hypersensitivity. | 2012 | Inflammation | pmid:21336676 |
Ichiki H et al. | [A study of adverse drug reactions in the treatment of pulmonary Mycobacterium avium complex disease]. | 2012 | Kekkaku | pmid:22993889 |
Schluger NW | Treatment of pulmonary Mycobacterium avium complex infections: do drug levels matter? | 2012 | Am. J. Respir. Crit. Care Med. | pmid:23071188 |
Li K and Haber RM | Stevens-Johnson syndrome without skin lesions (Fuchs syndrome): a literature review of adult cases with Mycoplasma cause. | 2012 | Arch Dermatol | pmid:22911206 |
Yang YH et al. | Anti-Helicobacter pylori effects of IgY from egg york of immunized hens. | 2012 | Lab Anim Res | pmid:22474475 |
Li H et al. | [Clarithromycin combined with tanshinone for rhinosinusal and laryngeal radiation injury in patients with nasopharyngeal carcinoma after radiotherapy]. | 2012 | Nan Fang Yi Ke Da Xue Xue Bao | pmid:22931614 |
Lee MR et al. | Otitis media and otomastoiditis caused by Mycobacterium massiliense (Mycobacterium abscessus subsp. bolletii). | 2012 | J. Clin. Microbiol. | pmid:22933592 |
van de Streek J | Reinterpretation of the monohydrate of clarithromycin from X-ray powder diffraction data as a trihydrate. | 2012 | Acta Crystallogr C | pmid:22935507 |
Grosso F et al. | A comprehensive safety analysis confirms rhabdomyolysis as an uncommon adverse reaction in patients treated with trabectedin. | 2012 | Cancer Chemother. Pharmacol. | pmid:22484722 |
Federico A et al. | Efficacy of 5-day levofloxacin-containing concomitant therapy in eradication of Helicobacter pylori infection. | 2012 | Gastroenterology | pmid:22484118 |
Arora S and Budhiraja RD | Chitosan-alginate microcapsules of amoxicillin for gastric stability and mucoadhesion. | 2012 | J Adv Pharm Technol Res | pmid:22470897 |
Ablanedo-Terrazas Y et al. | Palatal Actinomycosis and Kaposi Sarcoma in an HIV-Infected Subject with Disseminated Mycobacterium avium-intracellulare Infection. | 2012 | Case Rep Med | pmid:22481952 |
Humphrey B et al. | Fitness of Escherichia coli strains carrying expressed and partially silent IncN and IncP1 plasmids. | 2012 | BMC Microbiol. | pmid:22475035 |
Rozza AL et al. | Morphologic and pharmacological investigations in the epicatechin gastroprotective effect. | 2012 | Evid Based Complement Alternat Med | pmid:22666296 |
Noto MJ and Wheeler AP | Macrolides for acute lung injury. | 2012 | Chest | pmid:22553255 |
Martins TG et al. | Local and regional re-establishment of cellular immunity during curative antibiotherapy of murine Mycobacterium ulcerans infection. | 2012 | PLoS ONE | pmid:22393444 |
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Kobashi Y et al. | Pulmonary Mycobacterium kyorinense disease showed clinical improvement following combined therapy with clarithromycin and levofloxacin. | 2012 | Intern. Med. | pmid:22821114 |
Li Y et al. | A data-driven predictive approach for drug delivery using machine learning techniques. | 2012 | PLoS ONE | pmid:22384063 |
Hong SJ | The Role of Mycoplasma pneumoniae Infection in Asthma. | 2012 | Allergy Asthma Immunol Res | pmid:22379599 |
Morisset J et al. | A case of difficult-to-treat eosinophilic asthma controlled with clarithromycin. | 2012 | Ann. Allergy Asthma Immunol. | pmid:22727169 |
Cavusoglu C et al. | Evaluation of antimicrobial susceptibilities of rapidly growing mycobacteria by Sensititre RAPMYCO panel. | 2012 | New Microbiol. | pmid:22378556 |
Sezikli M et al. | Efficacy of the Combination of Tetracycline, Amoxicillin, and Lansoprazole in the Eradication of Helicobacter pylori in Treatment-Naïve Patients and in Patients Who Are Not Responsive to Clarithromycin-Based Regimens: A Pilot Study. | 2012 | Gut Liver | pmid:22375169 |
Youn YS and Lee KY | Mycoplasma pneumoniae pneumonia in children. | 2012 | Korean J Pediatr | pmid:22375148 |
Gisbert JP et al. | Fourth-line rescue therapy with rifabutin in patients with three Helicobacter pylori eradication failures. | 2012 | Aliment. Pharmacol. Ther. | pmid:22372560 |
Terada M et al. | Antimicrobial efficacies of several antibiotics against uterine cervicitis caused by Mycoplasma genitalium. | 2012 | J. Infect. Chemother. | pmid:22020630 |