MeSH term | MeSH ID | Detail |
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Myxoma | D009232 | 1 associated lipids |
Kleine-Levin Syndrome | D017593 | 1 associated lipids |
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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[Experience with treatment of chronic polypoid rhinosinusitis using low doses of clarithromycin in the postoperative period]. | 2012 | Vestn. Otorinolaringol. | pmid:22678641 | |
Robinson JG | Management of complex lipid abnormalities with a fixed dose combination of simvastatin and extended release niacin. | 2009 | Vasc Health Risk Manag | pmid:19436666 |
Kones R | Recent advances in the management of chronic stable angina II. Anti-ischemic therapy, options for refractory angina, risk factor reduction, and revascularization. | 2010 | Vasc Health Risk Manag | pmid:20859545 |
Bronander KA and Bloch MJ | Potential role of the endocannabinoid receptor antagonist rimonabant in the management of cardiometabolic risk: a narrative review of available data. | 2007 | Vasc Health Risk Manag | pmid:17580728 |
Wolbrette D et al. | Dronedarone for the treatment of atrial fibrillation and atrial flutter: approval and efficacy. | 2010 | Vasc Health Risk Manag | pmid:20730068 |
Falk JA et al. | The emergence of oral tadalafil as a once-daily treatment for pulmonary arterial hypertension. | 2010 | Vasc Health Risk Manag | pmid:20479949 |
Edmonds M | The treatment of diabetic foot infections: focus on ertapenem. | 2009 | Vasc Health Risk Manag | pmid:19997576 |
Laks T et al. | Achieving lipid goals with rosuvastatin compared with simvastatin in high risk patients in real clinical practice: a randomized, open-label, parallel-group, multi-center study: the DISCOVERY-Beta study. | 2008 | Vasc Health Risk Manag | pmid:19337553 |
Lee CK et al. | Immunization with recombinant Helicobacter pylori urease decreases colonization levels following experimental infection of rhesus monkeys. | 1999 | Vaccine | pmid:10195786 |
Rendi-Wagner P et al. | National paediatric immunization program of high risk groups: no effect on the incidence of invasive pneumococcal diseases. | 2009 | Vaccine | pmid:19393711 |
Gao M et al. | The effects of transrectal radiofrequency hyperthermia on patients with chronic prostatitis and the changes of MDA, NO, SOD, and Zn levels in pretreatment and posttreatment. | 2012 | Urology | pmid:22100490 |
El-Garem Y et al. | Seminal Helicobacter pylori treatment improves sperm motility in infertile asthenozoospermic men. | 2014 | Urology | pmid:25432826 |
Lange JN et al. | Sensitivity of human strains of Oxalobacter formigenes to commonly prescribed antibiotics. | 2012 | Urology | pmid:22656407 |
NeÄmark AI et al. | [Efficacy of low-intensity laser radiation and antibacterial therapy in the treatment of chronic prostatitis in the presence of sexually transmitted infections]. | 2007 May-Jun | Urologiia | pmid:17724830 |
Yoshida K et al. | Chlamydia trachomatis infection in the semen of asymptomatic infertile men: detection of the antigen by in situ hybridization. | 1994 | Urol. Int. | pmid:7855940 |
Velho PE et al. | Severe anemia, panserositis, and cryptogenic hepatitis in an HIV patient infected with Bartonella henselae. | 2007 Nov-Dec | Ultrastruct Pathol | pmid:18098054 |
Schouenborg P | [Clarithromycin]. | 1996 | Ugeskr. Laeg. | pmid:8686028 |
Schmidt BJ and Hermansen MN | [Late debut of neonatal pneumonia caused by Chlamydia trachomatis]. | 2013 | Ugeskr. Laeg. | pmid:23428270 |
Petersen AM et al. | [Resistance of Helicobacter pylori to clarithomycin]. | 1998 | Ugeskr. Laeg. | pmid:9627511 |
Buch T and Andersen SE | [Combination therapy with fluconazole and other QTc-prolonging drugs increase the QTc interval]. | 2015 | Ugeskr. Laeg. | pmid:26471025 |