| MeSH term | MeSH ID | Detail |
|---|---|---|
| Myxoma | D009232 | 1 associated lipids |
| Kleine-Levin Syndrome | D017593 | 1 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- J. Antimicrob. Chemother. (1)
- Clin. Diagn. Lab. Immunol. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mikamo H et al. | In vitro and in vivo antibacterial activities of telithromycin. | 2003 | Chemotherapy | pmid:12714813 |
| Sargýn M et al. | Type 2 diabetes mellitus affects eradication rate of Helicobacter pylori. | 2003 | World J. Gastroenterol. | pmid:12717872 |
| Liebowitz LD et al. | National surveillance programme on susceptibility patterns of respiratory pathogens in South Africa: moxifloxacin compared with eight other antimicrobial agents. | 2003 | J. Clin. Pathol. | pmid:12719453 |
| Dimopoulos MA et al. | Treatment of Waldenstrom's macroglobulinemia with single-agent thalidomide or with the combination of clarithromycin, thalidomide and dexamethasone. | 2003 | Semin. Oncol. | pmid:12720150 |
| Coleman M et al. | Treatment of Waldenstrom's macroglobulinemia with clarithromycin, low-dose thalidomide, and dexamethasone. | 2003 | Semin. Oncol. | pmid:12720151 |
| Nagai H | [Nontuberculous mycobacteriosis]. | 2003 | Nippon Rinsho | pmid:12722274 |
| Asaka M | [Guidelines in the management of Helicobacter pylori infection in Japan]. | 2003 | Nippon Rinsho | pmid:12722304 |
| Marzio L et al. | Triple therapy for 7 days vs. triple therapy for 7 days plus omeprazole for 21 days in treatment of active duodenal ulcer with Helicobacter pylori infection. A double blind placebo controlled trial. | 2003 | Dig Liver Dis | pmid:12725603 |
| Yang WK et al. | Mycobacterium avium complex-associated hemophagocytic syndrome in systemic lupus erythematosus patient: report of one case. | 2003 | Lupus | pmid:12729056 |
| Matsuo K et al. | Smoking and polymorphisms of fucosyltransferase gene Le affect success of H. pylori eradication with lansoprazole, amoxicillin, and clarithromycin. | 2003 | Epidemiol. Infect. | pmid:12729191 |
| Zhao Y et al. | A novel bicyclic ketolide derivative. | 2003 | Bioorg. Med. Chem. Lett. | pmid:12729669 |
| Hoban D et al. | Antimicrobial susceptibility of community-acquired respiratory tract pathogens in North America in 1999-2000: findings of the PROTEKT surveillance study. | 2003 | Diagn. Microbiol. Infect. Dis. | pmid:12729995 |
| Furuta T et al. | Therapeutic impact of CYP2C19 pharmacogenetics on proton pump inhibitor-based eradication therapy for Helicobacter pylori. | 2003 | Methods Find Exp Clin Pharmacol | pmid:12731459 |
| Krause R et al. | Puumala virus infection with acute disseminated encephalomyelitis and multiorgan failure. | 2003 | Emerging Infect. Dis. | pmid:12737748 |
| Wada S et al. | [Antimicrobial susceptibility tests and resistant strain of Helicobacter pylori]. | 2003 | Kansenshogaku Zasshi | pmid:12739371 |
| Kaise M et al. | Helicobacter pylori stimulates inducible nitric oxide synthase in diverse topographical patterns in various gastroduodenal disorders. | 2003 | Dig. Dis. Sci. | pmid:12741449 |
| Asaka M et al. | Follow-up survey of a large-scale multicenter, double-blind study of triple therapy with lansoprazole, amoxicillin, and clarithromycin for eradication of Helicobacter pylori in Japanese peptic ulcer patients. | 2003 | J. Gastroenterol. | pmid:12743773 |
| Miyamoto M et al. | Isolated granulomatous gastritis successfully treated by Helicobacter pylori eradication: a possible association between granulomatous gastritis and Helicobacter pylori. | 2003 | J. Gastroenterol. | pmid:12743778 |
| Sánchez F et al. | Is azithromycin the first-choice macrolide for treatment of community-acquired pneumonia? | 2003 | Clin. Infect. Dis. | pmid:12746768 |
| Quinn J et al. | Efficacy and tolerability of 5-day, once-daily telithromycin compared with 10-day, twice-daily clarithromycin for the treatment of group A beta-hemolytic streptococcal tonsillitis/pharyngitis: a multicenter, randomized, double-blind, parallel-group study. | 2003 | Clin Ther | pmid:12749505 |
| Vega AE et al. | [Detection of resistance to clarithromycin in clinical isolates of Helicobacter pylori from children and adults]. | 2003 | Rev Esp Quimioter | pmid:12750757 |
| Gordillo RM et al. | [Susceptibility of Streptococcus pyogenes isolates from pharyngeal exudates in Cordoba (Spain)]. | 2003 | Rev Esp Quimioter | pmid:12750758 |
| Eisig JN et al. | Therapeutic efficacy of ranitidine bismuth citrate with clarithromycin for seven days in the eradication of Helicobacter pylori in Brazilian peptic ulcer patients. | 2003 | Sao Paulo Med J | pmid:12751338 |
| Malfertheiner P et al. | Helicobacter pylori eradication and gastric ulcer healing--comparison of three pantoprazole-based triple therapies. | 2003 | Aliment. Pharmacol. Ther. | pmid:12752349 |
| Gené E et al. | Triple vs. quadruple therapy for treating Helicobacter pylori infection: a meta-analysis. | 2003 | Aliment. Pharmacol. Ther. | pmid:12752350 |
| Kim JJ et al. | Mixed-infection of antibiotic susceptible and resistant Helicobacter pylori isolates in a single patient and underestimation of antimicrobial susceptibility testing. | 2003 | Helicobacter | pmid:12752732 |
| Ohno T et al. | Antimicrobial activity of essential oils against Helicobacter pylori. | 2003 | Helicobacter | pmid:12752733 |
| Pachot JI et al. | Experimental estimation of the role of P-Glycoprotein in the pharmacokinetic behaviour of telithromycin, a novel ketolide, in comparison with roxithromycin and other macrolides using the Caco-2 cell model. | J Pharm Pharm Sci | pmid:12753725 | |
| Graham DY et al. | Meta-analysis: proton pump inhibitor or H2-receptor antagonist for Helicobacter pylori eradication. | 2003 | Aliment. Pharmacol. Ther. | pmid:12755836 |
| Sheu BS et al. | The selection of triple therapy for Helicobacter pylori eradication in chronic renal insufficiency. | 2003 | Aliment. Pharmacol. Ther. | pmid:12755841 |
| Ives TJ et al. | Disposition and functions of clarithromycin in human THP-1 monocytes during stimulated and unstimulated conditions. | 2001 | Res. Commun. Mol. Pathol. Pharmacol. | pmid:12760488 |
| Boixeda D et al. | Seven-day proton pump inhibitor, amoxicillin and clarithromycin triple therapy. factors that influence Helicobacter pylori eradications success. | 2003 | Rev Esp Enferm Dig | pmid:12760710 |
| Gisbert JP et al. | Validation of the 13c-urea breath test for the initial diagnosis of helicobacter pylori infection and to confirm eradication after treatment. | 2003 | Rev Esp Enferm Dig | pmid:12760719 |
| Yamaguchi H et al. | Chlamydia pneumoniae resists antibiotics in lymphocytes. | 2003 | Antimicrob. Agents Chemother. | pmid:12760877 |
| Parsad D et al. | A guide to selection and appropriate use of macrolides in skin infections. | 2003 | Am J Clin Dermatol | pmid:12762831 |
| Hon KL et al. | Clinical presentations and outcome of severe acute respiratory syndrome in children. | 2003 | Lancet | pmid:12767737 |
| Eun CS et al. | Changing pattern of antimicrobial resistance of Helicobacter pylori in Korean patients with peptic ulcer diseases. | 2003 | J. Gastroenterol. | pmid:12768385 |
| Miwa H and Sato N | Reality and false premises of antimicrobial susceptibility testing for Helicobacter pylori. | 2003 | J. Gastroenterol. | pmid:12768400 |
| Kobayashi K et al. | [A case of M. avium lung disease complicated with adenocarcinoma]. | 2003 | Nihon Kokyuki Gakkai Zasshi | pmid:12772596 |
| Sipe BE et al. | Rhabdomyolysis causing AV blockade due to possible atorvastatin, esomeprazole, and clarithromycin interaction. | 2003 | Ann Pharmacother | pmid:12773066 |
| Borrás-Blasco J et al. | Henoch-Schönlein purpura associated with clarithromycin. Case report and review of literature. | 2003 | Int J Clin Pharmacol Ther | pmid:12776812 |
| Abbas SZ et al. | Diagnosis and eradication of Helicobacter pylori in patients with duodenal ulceration in the community. | 2003 | J Pak Med Assoc | pmid:12779020 |
| Sarnelli G et al. | Acid exposure and altered acid clearance in GERD patients treated for Helicobacter pylori infection. | 2003 | Dig Liver Dis | pmid:12779068 |
| Daines BS et al. | Rapid diagnosis and treatment of mycobacterial keratitis after laser in situ keratomileusis. | 2003 | J Cataract Refract Surg | pmid:12781292 |
| Mégraud F and Lamouliatte H | Review article: the treatment of refractory Helicobacter pylori infection. | 2003 | Aliment. Pharmacol. Ther. | pmid:12786627 |
| Veldhuyzen Van Zanten S et al. | One-week triple therapy with esomeprazole, clarithromycin and metronidazole provides effective eradication of Helicobacter pylori infection. | 2003 | Aliment. Pharmacol. Ther. | pmid:12786632 |
| Waites KB et al. | Inhibitory and bactericidal activities of gemifloxacin and other antimicrobials against Mycoplasma pneumoniae. | 2003 | Int. J. Antimicrob. Agents | pmid:12791472 |
| Roblin PM et al. | In vitro activity of garenoxacin against recent clinical isolates of Chlamydia pneumoniae. | 2003 | Int. J. Antimicrob. Agents | pmid:12791473 |
| Bermudez LE et al. | Mefloquine, moxifloxacin, and ethambutol are a triple-drug alternative to macrolide-containing regimens for treatment of Mycobacterium avium disease. | 2003 | J. Infect. Dis. | pmid:12792877 |
| Unge P et al. | Do Japanese and Swedish peptic ulcer patients respond differently to Helicobacter pylori eradication therapies and what are their histological features? | 2003 | Scand. J. Gastroenterol. | pmid:12795457 |
| Roghani HS et al. | Effect of different doses of furazolidone with amoxicillin and omeprazole on eradication of Helicobacter pylori. | 2003 | J. Gastroenterol. Hepatol. | pmid:12795748 |
| Mario FD et al. | Rabeprazole in a one-week eradication therapy of Helicobacter pylori: comparison of different dosages. | 2003 | J. Gastroenterol. Hepatol. | pmid:12795749 |
| Lohitnavy M et al. | Average bioequivalence study of clarithromycin tablets in healthy male volunteers. | 2003 | J Clin Pharm Ther | pmid:12795777 |
| Sapone A et al. | The clinical role of cytochrome p450 genotypes in Helicobacter pylori management. | 2003 | Am. J. Gastroenterol. | pmid:12809821 |
| Kullavanijaya P et al. | Disseminated Mycobacterium chelonae cutaneous infection: recalcitrant to combined antibiotic therapy. | 2003 | J. Dermatol. | pmid:12810998 |
| Anderegg TR et al. | Re-evaluation of quality control guidelines for gatifloxacin and garenoxacin (BMS284756) when susceptibility testing Haemophilus influenzae and Streptococcus pneumoniae. | 2003 | Diagn. Microbiol. Infect. Dis. | pmid:12812719 |
| Hagberg L et al. | Telithromycin in the treatment of community-acquired pneumonia: a pooled analysis. | 2003 | Respir Med | pmid:12814146 |
| Ito K et al. | Prediction of the in vivo interaction between midazolam and macrolides based on in vitro studies using human liver microsomes. | 2003 | Drug Metab. Dispos. | pmid:12814973 |
| Mah Ming JB and Gill MJ | Drug-induced rhabdomyolysis after concomitant use of clarithromycin, atorvastatin, and lopinavir/ritonavir in a patient with HIV. | 2003 | AIDS Patient Care STDS | pmid:12816614 |
| Terzano C and Petroianni A | Clarithromycin and pulmonary infiltration with eosinophilia. | 2003 | BMJ | pmid:12816827 |
| Kaneko Y et al. | Clarithromycin inhibits overproduction of muc5ac core protein in murine model of diffuse panbronchiolitis. | 2003 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:12818892 |
| van Zanten SJ et al. | Gastric transitional zones, areas where Helicobacter treatment fails: results of a treatment trial using the Sydney strain mouse model. | 2003 | Antimicrob. Agents Chemother. | pmid:12821476 |
| Sasaki A et al. | Long-term observation of reflux oesophagitis developing after Helicobacter pylori eradication therapy. | 2003 | Aliment. Pharmacol. Ther. | pmid:12823156 |
| Miwa H et al. | Is antimicrobial susceptibility testing necessary before second-line treatment for Helicobacter pylori infection? | 2003 | Aliment. Pharmacol. Ther. | pmid:12823158 |
| Lee SJ et al. | Characterization of the first Korean isolate of a Chlamydia pneumoniae strain. | 2003 | Jpn. J. Infect. Dis. | pmid:12824688 |
| Iwao E et al. | In vitro and in vivo anti- Helicobacter pylori activity of Y-904, a new fluoroquinolone. | 2003 | J. Infect. Chemother. | pmid:12825117 |
| Cone LA et al. | Delirium in the elderly resulting from azithromycin therapy. | 2003 | Surg Neurol | pmid:12826358 |
| Ohara T et al. | Eradication therapy of Helicobacter pylori directly induces apoptosis in inflammation-related immunocytes in the gastric mucosa--possible mechanism for cure of peptic ulcer disease and MALT lymphoma with a low-grade malignancy. | 2003 May-Jun | Hepatogastroenterology | pmid:12828043 |
| Burton DY et al. | The incorporation of an ion channel gene mutation associated with the long QT syndrome (Q9E-hMiRP1) in a plasmid vector for site-specific arrhythmia gene therapy: in vitro and in vivo feasibility studies. | 2003 | Hum. Gene Ther. | pmid:12828861 |
| Shimizu T et al. | In vivo and in vitro effects of macrolide antibiotics on mucus secretion in airway epithelial cells. | 2003 | Am. J. Respir. Crit. Care Med. | pmid:12829454 |
| Spencer S and Jones PW | Time course of recovery of health status following an infective exacerbation of chronic bronchitis. | 2003 | Thorax | pmid:12832673 |
| Cynamon MH et al. | Activity of clarithromycin alone and in combination in a murine model of Mycobacterium kansasii infection. | 2003 | J. Antimicrob. Chemother. | pmid:12837729 |
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| Wheeldon TU et al. | Helicobacter pylori eradication and peptic ulcer healing: the impact of deleting the proton pump inhibitor and using a once-daily treatment. | 2003 | Aliment. Pharmacol. Ther. | pmid:12848630 |
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| Blosser-Middleton R et al. | Antimicrobial susceptibility of 840 clinical isolates of Haemophilus influenzae collected in four European countries in 2000-2001. | 2003 | Clin. Microbiol. Infect. | pmid:12848759 |
| Fernández-Cuenca F et al. | Evaluation of the WIDER I system for antimicrobial susceptibility testing of clinical isolates of Haemophilus influenzae and Streptococcus pneumoniae. | 2003 | Clin. Microbiol. Infect. | pmid:12848763 |
| Rengelshausen J et al. | Contribution of increased oral bioavailability and reduced nonglomerular renal clearance of digoxin to the digoxin-clarithromycin interaction. | 2003 | Br J Clin Pharmacol | pmid:12848773 |
| Berg HF et al. | Effect of clarithromycin on inflammatory markers in patients with atherosclerosis. | 2003 | Clin. Diagn. Lab. Immunol. | pmid:12853380 |
| Scharer G et al. | Systemic inflammatory responses in children with acute otitis media due to Streptococcus pneumoniae and the impact of treatment with clarithromycin. | 2003 | Clin. Diagn. Lab. Immunol. | pmid:12853412 |
| Lai YC et al. | Density of Helicobacter pylori may affect the efficacy of eradication therapy and ulcer healing in patients with active duodenal ulcers. | 2003 | World J. Gastroenterol. | pmid:12854158 |
| Kadota J et al. | Long-term efficacy and safety of clarithromycin treatment in patients with diffuse panbronchiolitis. | 2003 | Respir Med | pmid:12854636 |
| Ushiyama A et al. | Lactobacillus gasseri OLL2716 as a probiotic in clarithromycin-resistant Helicobacter pylori infection. | 2003 | J. Gastroenterol. Hepatol. | pmid:12859730 |
| Corrêa JC et al. | Randomized, open-label, parallel-group, multicenter study of the efficacy and tolerability of IV gatifloxacin with the option for oral stepdown gatifloxacin versus IV ceftriaxone (with or without erythromycin or clarithromycin) with the option for oral stepdown clarithromycin for treatment of patients with mild to moderate community-acquired pneumonia requiring hospitalization. | 2003 | Clin Ther | pmid:12867221 |
| Mason EO et al. | Macrolide resistance among middle ear isolates of Streptococcus pneumoniae observed at eight United States pediatric centers: prevalence of M and MLSB phenotypes. | 2003 | Pediatr. Infect. Dis. J. | pmid:12867838 |
| Kamada T et al. | The long-term effect of Helicobacter pylori eradication therapy on symptoms in dyspeptic patients with fundic atrophic gastritis. | 2003 | Aliment. Pharmacol. Ther. | pmid:12869086 |
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| Keserü GM | Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. | 2003 | Bioorg. Med. Chem. Lett. | pmid:12873512 |
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| Rerksuppaphol S et al. | Antimicrobial resistance in Helicobacter pylori isolates from children. | 2003 | J Paediatr Child Health | pmid:12887661 |
| Ahn CY et al. | Effects of cysteine on the pharmacokinetics of intravenous clarithromycin in rats with protein-calorie malnutrition. | 2003 | Life Sci. | pmid:12888117 |
| Buxbaum A et al. | Comparative activity of telithromycin against typical community-acquired respiratory pathogens. | 2003 | J. Antimicrob. Chemother. | pmid:12888585 |
| Gotfried MH et al. | Steady-state plasma and bronchopulmonary characteristics of clarithromycin extended-release tablets in normal healthy adult subjects. | 2003 | J. Antimicrob. Chemother. | pmid:12888589 |
| Lohitnavy M et al. | Average bioequivalence of clarithromycin immediate released tablet formulations in healthy male volunteers. | 2003 | Drug Dev Ind Pharm | pmid:12889783 |
| Moreira A et al. | Is Helicobacter pylori infection associated with chronic idiopathic urticaria? | Allergol Immunopathol (Madr) | pmid:12890412 | |
| Prónai L and Tulassay Z | [Failure of Helicobacter pylori eradication--suggestions for further therapy]. | 2003 | Orv Hetil | pmid:12894674 |
| Chi CH et al. | Quadruple therapy containing amoxicillin and tetracycline is an effective regimen to rescue failed triple therapy by overcoming the antimicrobial resistance of Helicobacter pylori. | 2003 | Aliment. Pharmacol. Ther. | pmid:12895220 |
| Takaki M et al. | The role of nuclear factor-kappa B in interleukin-8 expression by human adenoidal fibroblasts. | 2003 | Laryngoscope | pmid:12897563 |