MeSH term | MeSH ID | Detail |
---|---|---|
Myxoma | D009232 | 1 associated lipids |
Kleine-Levin Syndrome | D017593 | 1 associated lipids |
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Tietz A et al. | Fulminant liver failure associated with clarithromycin. | 2003 | Ann Pharmacother | pmid:12503933 |
Gerónimo-Pardo M et al. | Clarithromycin-nifedipine interaction as possible cause of vasodilatory shock. | 2005 | Ann Pharmacother | pmid:15703161 |
Marra F et al. | A comparison of antibiotic use in children between Canada and Denmark. | 2007 | Ann Pharmacother | pmid:17374628 |
Juurlink DN and Ito S | Comment: clarithromycin-digoxin interaction. | 1999 | Ann Pharmacother | pmid:10630847 |
Rao KB et al. | Enhanced hypoprothrombinemia with warfarin due to azithromycin. | 2004 | Ann Pharmacother | pmid:15084685 |
Sipe BE et al. | Rhabdomyolysis causing AV blockade due to possible atorvastatin, esomeprazole, and clarithromycin interaction. | 2003 | Ann Pharmacother | pmid:12773066 |
Basyigit I et al. | The effect of clarithromycin on inflammatory markers in chronic obstructive pulmonary disease: preliminary data. | 2004 | Ann Pharmacother | pmid:15252191 |
De Bruin ML et al. | Use of cisapride with contraindicated drugs in The Netherlands. | 2002 | Ann Pharmacother | pmid:11847959 |
Varner TR et al. | Role of rifampin-based combination therapy for severe community-acquired Legionella pneumophila pneumonia. | 2011 | Ann Pharmacother | pmid:21775694 |
Courter JD et al. | Increased clinical failures when treating acute otitis media with macrolides: a meta-analysis. | 2010 | Ann Pharmacother | pmid:20150506 |
Bahal N and Nahata MC | The new macrolide antibiotics: azithromycin, clarithromycin, dirithromycin, and roxithromycin. | 1992 | Ann Pharmacother | pmid:1318761 |
Rollot F et al. | Acute colchicine intoxication during clarithromycin administration. | 2004 | Ann Pharmacother | pmid:15494379 |
Ibrahim RB et al. | Tacrolimus-clarithromycin interaction in a patient receiving bone marrow transplantation. | 2002 | Ann Pharmacother | pmid:12452763 |
Tseng AL and Walmsley SL | Rifabutin-associated uveitis. | 1995 | Ann Pharmacother | pmid:8573961 |
Kahri AJ et al. | Rhabdomyolysis associated with concomitant use of simvastatin and clarithromycin. | 2004 | Ann Pharmacother | pmid:14966253 |
Tanaka H et al. | Effect of clarithromycin on steady-state digoxin concentrations. | 2003 | Ann Pharmacother | pmid:12549942 |
Gavura SR and Nusinowitz S | Leukocytoclastic vasculitis associated with clarithromycin. | 1998 | Ann Pharmacother | pmid:9606474 |
Lee AJ and Maddix DS | Rhabdomyolysis secondary to a drug interaction between simvastatin and clarithromycin. | 2001 | Ann Pharmacother | pmid:11197581 |
Sturgill MG and Rapp RP | Clarithromycin: review of a new macrolide antibiotic with improved microbiologic spectrum and favorable pharmacokinetic and adverse effect profiles. | 1992 | Ann Pharmacother | pmid:1421677 |
Giannattasio A et al. | Steroid therapy for a case of severe drug-induced cholestasis. | 2006 | Ann Pharmacother | pmid:16720710 |
Tracy TS and Johns M | Comment: delirium probably induced by clarithromycin in a patient receiving fluoxetine. | 1996 | Ann Pharmacother | pmid:8893135 |
Sungur C | Acute rheumatic fever despite clarithromycin treatment of beta-hemolytic streptococcal tonsillitis. | 1994 | Ann Pharmacother | pmid:7841580 |
Nawarskas JJ et al. | Digoxin toxicity secondary to clarithromycin therapy. | 1997 Jul-Aug | Ann Pharmacother | pmid:9220047 |
Recker MW and Kier KL | Potential interaction between clarithromycin and warfarin. | 1997 | Ann Pharmacother | pmid:9296238 |
Laberge P and Martineau P | Clarithromycin-induced digoxin intoxication. | 1997 | Ann Pharmacother | pmid:9296239 |
Widgerow AD et al. | Atypical Mycobacterium and breast surgery. | 1995 | Ann Plast Surg | pmid:7486746 |
Issa H et al. | Bleeding duodenal ulcer after Roux-en-Y gastric bypass surgery: the value of laparoscopic gastroduodenoscopy. | Ann Saudi Med | pmid:20103961 | |
Varghese B et al. | First case report of chronic pulmonary lung disease caused by Mycobacterium abscessus in two immunocompetent patients in Saudi Arabia. | Ann Saudi Med | pmid:22588446 | |
Moosavian M et al. | Rapid detection of clarithromycin-resistant Helicobacter pylori in patients with dyspepsia by fluorescent in situ hybridization (FISH) compared with the E-test. | 2007 Mar-Apr | Ann Saudi Med | pmid:17356313 |
Al-Benwan K et al. | Diagnosis of endocarditis caused by Mycobacterium abscessus. | 2010 Sep-Oct | Ann Saudi Med | pmid:20697162 |
Kikuchi R et al. | A case of Good's syndrome: a rare acquired immunodeficiency associated with thymoma. | 2011 | Ann Thorac Cardiovasc Surg | pmid:21587135 |
Wali S | Mycobacterium chelonae empyema with bronchopleural fistula in an immunocompetent patient. | 2009 | Ann Thorac Med | pmid:19881169 |
Tanih NF et al. | Characterisation of the genes encoding resistance to metronidazole (rdxA and frxA) and clarithromycin (the 23S-rRNA genes) in South African isolates of Helicobacter pylori. | 2011 | Ann Trop Med Parasitol | pmid:21801504 |
Tan HH et al. | Cutaneous Mycobacterium haemophilum infections in immunocompromised patients in a dermatology clinic in Singapore. | 2004 | Ann. Acad. Med. Singap. | pmid:15329772 |
Lee HY et al. | Unresolving furunculosis in a diabetic patient: cutaneous Mycobacterium abscessus infection. | 2009 | Ann. Acad. Med. Singap. | pmid:19271048 |
Amayasu H et al. | Clarithromycin suppresses bronchial hyperresponsiveness associated with eosinophilic inflammation in patients with asthma. | 2000 | Ann. Allergy Asthma Immunol. | pmid:10875487 |
Dubini M et al. | Multiple drug allergy: A case of anaphylaxis to levofloxacin but tolerance to ciprofloxacin. | 2016 | Ann. Allergy Asthma Immunol. | pmid:27009438 |
Fonseca-Aten M et al. | Effect of clarithromycin on cytokines and chemokines in children with an acute exacerbation of recurrent wheezing: a double-blind, randomized, placebo-controlled trial. | 2006 | Ann. Allergy Asthma Immunol. | pmid:17069099 |
Hahn DL et al. | Evidence for Chlamydia pneumoniae infection in steroid-dependent asthma. | 1998 | Ann. Allergy Asthma Immunol. | pmid:9475566 |
Swamy N et al. | Successful clarithromycin desensitization in a multiple macrolide-allergic patient. | 2010 | Ann. Allergy Asthma Immunol. | pmid:21130389 |
McCarty JM and Pierce PF | Five days of cefprozil versus 10 days of clarithromycin in the treatment of an acute exacerbation of chronic bronchitis. | 2001 | Ann. Allergy Asthma Immunol. | pmid:11686426 |
Spahn JD et al. | Clarithromycin potentiates glucocorticoid responsiveness in patients with asthma: results of a pilot study. | 2001 | Ann. Allergy Asthma Immunol. | pmid:11770698 |
Mori F et al. | Sensitivity and specificity of skin tests in the diagnosis of clarithromycin allergy. | 2010 | Ann. Allergy Asthma Immunol. | pmid:20486332 |
Morisset J et al. | A case of difficult-to-treat eosinophilic asthma controlled with clarithromycin. | 2012 | Ann. Allergy Asthma Immunol. | pmid:22727169 |
Randhawa I and Klaustermeyer WB | Oral corticosteroid-dependent asthma: a 30-year review. | 2007 | Ann. Allergy Asthma Immunol. | pmid:17941275 |
Sevin E et al. | [Helicobacter pylori: identification and detection of clarithromycin resistance by gene amplification]. | 2000 Jan-Feb | Ann. Biol. Clin. (Paris) | pmid:10673617 |
Destura RV et al. | Laboratory diagnosis and susceptibility profile of Helicobacter pylori infection in the Philippines. | 2004 | Ann. Clin. Microbiol. Antimicrob. | pmid:15546485 |
Valentini P et al. | An uncommon presentation for a severe invasive infection due to methicillin-resistant Staphylococcus aureus clone USA300 in Italy: a case report. | 2008 | Ann. Clin. Microbiol. Antimicrob. | pmid:18447939 |
Ribeiro ML et al. | Mutations in the 23S rRNA gene are associated with clarithromycin resistance in Helicobacter pylori isolates in Brazil. | 2003 | Ann. Clin. Microbiol. Antimicrob. | pmid:14633281 |
Jenkins SG et al. | Trends in antibacterial resistance among Streptococcus pneumoniae isolated in the USA: update from PROTEKT US Years 1-4. | 2008 | Ann. Clin. Microbiol. Antimicrob. | pmid:18190701 |