clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Bronchiolitis D001988 6 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Bronchitis D001991 6 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Chlamydia Infections D002690 7 associated lipids
Chromoblastomycosis D002862 2 associated lipids
Colitis D003092 69 associated lipids
Confusion D003221 4 associated lipids
Per page 10 20 50 100 | Total 242

PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Per page 10 20 50 100 | Total 7636
Authors Title Published Journal PubMed Link
Darling TN et al. Treatment of Mycobacterium haemophilum infection with an antibiotic regimen including clarithromycin. 1994 Br. J. Dermatol. pmid:7918014
Domschke W Omeprazole, Helicobacter pylori, and gastritis. 1994 J. Gastroenterol. pmid:7921141
Geraci AJ Empiric antibiotics in sinusitis. 1994 Arch Fam Med pmid:7921288
Rust GS Multicenter comparison of clarithromycin and amoxicillin. 1994 Arch Fam Med pmid:7921290
Sieber CC et al. [Helicobacter pylori resistance against metronidazole in Switzerland: implications for eradication therapy?]. 1994 Schweiz Med Wochenschr pmid:8091165
Dorrell L et al. Toxicity of clarithromycin in the treatment of Mycobacterium avium complex infection in a patient with AIDS. 1994 J. Antimicrob. Chemother. pmid:7868416
Funke G et al. Development of resistance to macrolide antibiotics in an AIDS patient treated with clarithromycin for Campylobacter jejuni diarrhea. 1994 Eur. J. Clin. Microbiol. Infect. Dis. pmid:7805694
Fujii R et al. [Clinical studies on clarithromycin dry syrup in the pediatric field. Pediatric Study Group of TE-031 Dry Syrup]. 1994 Jpn J Antibiot pmid:7807690
Labenz J and Stolte M [Current therapy of Helicobacter pylori infection]. 1994 Leber Magen Darm pmid:8145628
Logan RP et al. Eradication of Helicobacter pylori with clarithromycin and omeprazole. 1994 Gut pmid:8150340
Husson RN et al. Orally administered clarithromycin for the treatment of systemic Mycobacterium avium complex infection in children with acquired immunodeficiency syndrome. 1994 J. Pediatr. pmid:8176574
Alder J et al. Treatment of experimental Pneumocystis carinii infection by combination of clarithromycin and sulphamethoxazole. 1994 J. Antimicrob. Chemother. pmid:8182006
Tsang KW et al. The concentrations of clarithromycin and its 14-hydroxy metabolite in sputum of patients with bronchiectasis following single dose oral administration. 1994 J. Antimicrob. Chemother. pmid:8182010
Sundberg L and Cederberg A Penetration of clarithromycin and its 14-hydroxy metabolite into middle ear effusion in children with secretory otitis media. 1994 J. Antimicrob. Chemother. pmid:8182011
[Zeclar, a new antibiotic (clarithromycin 250 mg from Abbott laboratories]. 1994 Rev Infirm pmid:7652424
Antibiotic gets FDA nod for MAC treatment. 1994 Am J Nurs pmid:8304386
Yoshida K et al. Chlamydia trachomatis infection in the semen of asymptomatic infertile men: detection of the antigen by in situ hybridization. 1994 Urol. Int. pmid:7855940
Laing RB et al. New antimicrobials against Mycobacterium marinum infection. 1994 Br. J. Dermatol. pmid:7857853
Spiegl PV and Feiner CM Mycobacterium phlei infection of the foot: a case report. 1994 Foot Ankle Int pmid:7894643
Walker KJ et al. Evaluation of antimicrobial activities of clarithromycin and 14-hydroxyclarithromycin against three strains of Haemophilus influenzae by using an in vitro pharmacodynamic model. 1994 Antimicrob. Agents Chemother. pmid:7811010
Price DA et al. Clinical response to the addition of clarithromycin in Pneumocystis carinii pneumonia refractory to high dose co-trimoxazole. 1994 J. Antimicrob. Chemother. pmid:7814298
Tahara RW et al. The question of clarithromycin: a first-line drug for sinusitis? 1994 Arch Fam Med pmid:7818657
Pustorino S et al. [Effects of intravenous administration of clarithromycin on plasma levels of gastrin and group I pepsinogen]. 1994 Clin Ter pmid:7820984
Alder J et al. Treatment of experimental Toxoplasma gondii infection by clarithromycin-based combination therapy with minocycline or pyrimethamine. 1994 J. Acquir. Immune Defic. Syndr. pmid:7932081
Ferrari SL et al. The interaction between clarithromycin and cyclosporine in kidney transplant recipients. 1994 Transplantation pmid:7940695
Wüst J and Hardegger U Penetration of clarithromycin into human saliva. 1993 Sep-Oct Chemotherapy pmid:8370320
Scaglione F et al. A new model examining intracellular and extracellular activity of amoxicillin, azithromycin, and clarithromycin in infected cells. 1993 Nov-Dec Chemotherapy pmid:8222870
Ohmori S et al. Effects of clarithromycin and its metabolites on the mixed function oxidase system in hepatic microsomes of rats. 1993 Mar-Apr Drug Metab. Dispos. pmid:8097709
Wallace RJ et al. Drug intolerance to high-dose clarithromycin among elderly patients. 1993 Mar-Apr Diagn. Microbiol. Infect. Dis. pmid:8477575
Adam D Clarithromycin 250 mg b.i.d. for 5 or 10 days in the treatment of adult patients with purulent bronchitis. 1993 Jul-Aug Infection pmid:8225636
Coles SJ et al. A comparative study of clarithromycin and amoxycillin suspensions in the treatment of pediatric patients with acute otitis media. 1993 Jul-Aug Infection pmid:8225637
Miller CA Infections, resistant microbes, and older adults. 1993 Jan-Feb Geriatr Nurs pmid:8383085
Ritchie DJ et al. In vitro activity of clarithromycin, cefprozil, and other common oral antimicrobial agents against gram-positive and gram-negative pathogens. 1993 Jan-Feb Clin Ther pmid:8458040
Albani F et al. Clarithromycin-carbamazepine interaction: a case report. 1993 Jan-Feb Epilepsia pmid:8422851
Sader HS et al. In vitro activity of cefpodoxime compared with other oral cephalosporins tested against 5556 recent clinical isolates from five medical centers. 1993 Aug-Sep Diagn. Microbiol. Infect. Dis. pmid:8243035
Humphreys JE et al. A clarithromycin sensitivity survey in the United Kingdom using Stokes' method. 1993 J. Antimicrob. Chemother. pmid:8226438
Scaglione F et al. Immunostimulation by clarithromycin in healthy volunteers and chronic bronchitis patients. 1993 J Chemother pmid:8229150
Dautzenberg B et al. Clarithromycin and other antimicrobial agents in the treatment of disseminated Mycobacterium avium infections in patients with acquired immunodeficiency syndrome. 1993 Arch. Intern. Med. pmid:8427539
Neu HC and Chick TW Efficacy and safety of clarithromycin compared to cefixime as outpatient treatment of lower respiratory tract infections. 1993 Chest pmid:8222794
Kodama R et al. [Eradication therapy of Helicobacter pylori in gastroduodenal ulcer and its long-term course]. 1993 Nippon Rinsho pmid:8283646
Ji B et al. Powerful bactericidal activities of clarithromycin and minocycline against Mycobacterium leprae in lepromatous leprosy. 1993 J. Infect. Dis. pmid:8257487
Wettengel R et al. Clarithromycin versus cefaclor for the treatment of mild-to-moderate acute bacterial bronchitis. 1993 J. Antimicrob. Chemother. pmid:8360133
Nakashio S et al. [Antimicrobial activity of clarithromycin and its effect on bacterial adherence to medical material]. 1993 Jpn J Antibiot pmid:8360978
Mor N and Heifets L MICs and MBCs of clarithromycin against Mycobacterium avium within human macrophages. 1993 Antimicrob. Agents Chemother. pmid:8431006
Tomioka H et al. In vitro antimicrobial activity of benzoxazinorifamycin, KRM-1648, against Mycobacterium avium complex, determined by the radiometric method. 1993 Antimicrob. Agents Chemother. pmid:8431020
Chu SY et al. Effect of moderate or severe hepatic impairment on clarithromycin pharmacokinetics. 1993 J Clin Pharmacol pmid:8331208
Graham DY et al. Clarithromycin for the eradication of Helicobacter pylori. 1993 J. Clin. Gastroenterol. pmid:8331260
Esvant H et al. [Primary prophylaxis of cerebral toxoplasmosis in AIDS with clarithromycin]. 1993 Presse Med pmid:8337221
Lazard T et al. Efficacy of granulocyte colony-stimulating factor and RU-40555 in combination with clarithromycin against Mycobacterium avium complex infection in C57BL/6 mice. 1993 Antimicrob. Agents Chemother. pmid:7684213
Emori M et al. Therapeutic efficacy of the benzoxazinorifamycin KRM-1648 against experimental Mycobacterium avium infection induced in rabbits. 1993 Antimicrob. Agents Chemother. pmid:7684214