clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

Cross Reference

Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Hypercholesterolemia D006937 91 associated lipids
Bradycardia D001919 13 associated lipids
Endometriosis D004715 29 associated lipids
Myocardial Infarction D009203 21 associated lipids
Proteinuria D011507 30 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Arteriosclerosis D001161 86 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Fractures, Open D005597 3 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Fibrosis D005355 23 associated lipids
Tooth Discoloration D014075 7 associated lipids
Sinusitis D012852 9 associated lipids
Fusobacterium Infections D005674 3 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Psoriasis D011565 47 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Cross Infection D003428 9 associated lipids
Pseudomonas Infections D011552 25 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Per page 10 20 50 100 | Total 7636
Authors Title Published Journal PubMed Link
High-dose clarithromycin should be avoided. 1996 AIDS Alert pmid:11363723
Pot shots. 1996 Notes Undergr pmid:11363915
Bowersox J CPCRA researchers present OI studies at Vancouver. 1996 NIAID AIDS Agenda pmid:11363924
MAC management. 1996 PI Perspect pmid:11363967
Hultén K et al. New pharmacokinetic in vitro model for studies of antibiotic activity against intracellular microorganisms. 1996 Antimicrob. Agents Chemother. pmid:9124830
Xu G et al. Effect of macrolide antibiotics on macrophage functions. 1996 Microbiol. Immunol. pmid:8865152
Young LS Treatment and prophylaxis of Mycobacterium avium complex. 1996 Int J STD AIDS pmid:8652724
McCutchan JA Azithromycin in the prophylaxis of opportunistic infections in AIDS. 1996 Int J STD AIDS pmid:8652726
Flisch CW et al. [A case of arthritis of the wrist caused by Mycobacterium marinum. Review of the literature]. 1996 Ann Chir Main Memb Super pmid:9026056
Alarcón T et al. In vitro activity of omeprazole in combination with several antimicrobial agents against clinical isolates of Helicobacter pylori. 1996 Eur. J. Clin. Microbiol. Infect. Dis. pmid:9031877
Burucoa C et al. Western blot monitoring of disseminated Nocardia nova infection treated with clarithromycin, imipenem, and surgical drainage. 1996 Eur. J. Clin. Microbiol. Infect. Dis. pmid:9031879
Drouet M et al. [Unusual clinical form of amoxicillin allergy]. 1996 Allerg Immunol (Paris) pmid:9011169
Adachi T et al. Eosinophil apoptosis caused by theophylline, glucocorticoids, and macrolides after stimulation with IL-5. 1996 J. Allergy Clin. Immunol. pmid:8977529
Kondoh K et al. Inhibitory activity of clarithromycin on biofilm synthesis with Pseudomonas aeruginosa. 1996 Acta Otolaryngol Suppl pmid:8908271
Moreno JA et al. Significant increase in eradication rates of Helicobacter pylori infection with two consecutive dual therapies (omeprazole and amoxycillin or omeprazole and clarithromycin). A randomized study in 450 Spanish patients. 1996 J. Gastroenterol. pmid:8959519
Satoh K et al. Efficacy of clarithromycin in eradicating Helicobacter pylori. 1996 J. Gastroenterol. pmid:8959520
Shimoyama T et al. Ecabet sodium eradicates Helicobacter pylori infection in gastric ulcer patients. 1996 J. Gastroenterol. pmid:8959522
Tonokatsu Y et al. Eradication of Helicobacter pylori followed by reinfection. 1996 J. Gastroenterol. pmid:8959526
Murakami K et al. Atopic dermatitis successfully treated by eradication of Helicobacter pylori. 1996 J. Gastroenterol. pmid:8959527
Géhanno P et al. [Clarithromycin versus amoxicillin-clavulanic acid in the treatment of acute maxillary sinusitis in adults]. 1996 Pathol. Biol. pmid:8763594
Jordan WC Clarithromycin prophylaxis against Cryptosporidium enteritis in patients with AIDS. 1996 J Natl Med Assoc pmid:8764523
Xu G et al. [Effect of clarithromycin on cytocidal activity against Pseudomonas aeruginosa in mice peritoneal cavity]. 1996 Kansenshogaku Zasshi pmid:8822058
Pijpers E et al. A clarithromycin-induced myasthenic syndrome. 1996 Clin. Infect. Dis. pmid:8824993
Yousfi MM et al. Resolution of a metaplastic duodenal polyp after cure of Helicobacter pylori infection. 1996 J. Clin. Gastroenterol. pmid:8835902
Welsh L et al. In vitro activities of azithromycin, clarithromycin, erythromycin, and tetracycline against 13 strains of Chlamydia pneumoniae. 1996 Antimicrob. Agents Chemother. pmid:8787907
Lebrun L et al. Evaluation of the Etest for rapid susceptibility testing of Mycobacterium avium to clarithromycin. 1996 J. Antimicrob. Chemother. pmid:8737150
Brenciaglia MI et al. Inhibitory and bactericidal activity of rokitamycin against Helicobacter pylori and morphological alterations. 1996 J Chemother pmid:8981182
Markham A and McTavish D Clarithromycin and omeprazole as helicobacter pylori eradication therapy in patients with H. pylori-associated gastric disorders. 1996 Drugs pmid:8741237
Unge P Review of Helicobacter pylori eradication regimens. 1996 Scand. J. Gastroenterol. Suppl. pmid:8722388
Bazzoli F Italian omeprazole triple therapy--a 1-week regimen. 1996 Scand. J. Gastroenterol. Suppl. pmid:8722395
Goddard AF and Logan RP Antimicrobial resistance and Helicobacter pylori. 1996 J. Antimicrob. Chemother. pmid:8722530
Pinzani V et al. [Occurrence of anterior uveitis in a HIV patient treated with rifabutin, ethambutol, clarithromycin]. 1995 Sep-Oct Therapie pmid:8571297
Dalston MO et al. [Clarithromycin combined with pyrimethamine in cerebral toxoplasmosis--a report of 2 cases]. 1995 Oct-Dec Rev. Soc. Bras. Med. Trop. pmid:8668843
Sternon J et al. Azithromycin compared with clarithromycin in the treatment of adult patients with acute purulent tracheobronchitis: a cost of illness study. 1995 Nov-Dec J. Int. Med. Res. pmid:8746608
Stein GE et al. A preliminary study of clarithromycin versus doxycycline in the treatment of nongonococcal urethritis and mucopurulent cervicitis. 1995 Nov-Dec Pharmacotherapy pmid:8602379
Hashisaki GT Update on macrolide antibiotics. 1995 May-Jun Am J Otolaryngol pmid:7661309
Kees F et al. Serum and cellular pharmacokinetics of clarithromycin 500 mg q.d. and 250 mg b.i.d. in volunteers. 1995 May-Jun Infection pmid:7499006
Claussen DW The most commonly prescribed medications in the United States: Part 3. 1995 Jul-Aug Gastroenterol Nurs pmid:7654815
van der Meer JT and Danner SA Clarithromycin therapy for Mycobacterium avium complex bacteremia. 1995 Ann. Intern. Med. pmid:7778831
Burette A and Glupczynski Y Helicobacter pylori: the place of the new macrolides in the eradication of the bacteria in peptic ulcer disease. 1995 Infection pmid:7782116
Labenz J et al. One-week low-dose triple therapy for the eradication of Helicobacter pylori infection. 1995 Eur J Gastroenterol Hepatol pmid:7866820
Gill CJ et al. In vivo evaluation of three acid-stable azalide compounds, L-701,677, L-708,299 and L-708,365 compared to erythromycin, azithromycin and clarithromycin. 1995 J. Antibiot. pmid:7490222
Englishby VL Case reports of death associated with pseudomembranous colitis and clarithromycin. 1995 Eur J Gastroenterol Hepatol pmid:7496875
Schepp W [Omeprazole + clarithromycin + metronidazole--a new standard for eradication of Helicobacter pylori]. 1995 Z Gastroenterol pmid:7502558
Fabry W et al. Comparison of the E test and a proportion dilution method for susceptibility testing of Mycobacterium tuberculosis. 1995 Zentralbl. Bakteriol. pmid:9810662
Saito H et al. Therapeutic effect of KRM-1648 with various antimicrobials against Mycobacterium avium complex infection in mice. 1995 Tuber. Lung Dis. pmid:7718848
Hedenmo M and Eriksson BM Liquid chromatographic determination of the macrolide antibiotics roxithromycin and clarithromycin in plasma by automated solid-phase extraction and electrochemical detection. 1995 J Chromatogr A pmid:7719451
Atkinson BA et al. Treatment of Mycobacterium haemophilum infection in a murine model with clarithromycin, rifabutin, and ciprofloxacin. 1995 Antimicrob. Agents Chemother. pmid:8619588
Piersimoni C et al. Activity of seven antimicrobial agents, alone and in combination, against AIDS-associated isolates of Mycobacterium avium complex. 1995 J. Antimicrob. Chemother. pmid:8830013
Van Asselt GJ et al. Susceptibility of Streptococcus pyogenes to azithromycin, clarithromycin, erythromycin and roxithromycin in vitro. 1995 J. Med. Microbiol. pmid:7563004