clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

Cross Reference

Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Rickettsia Infections D012282 5 associated lipids
Splenic Diseases D013158 5 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Sexually Transmitted Diseases, Bacterial D015231 5 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Dyspepsia D004415 5 associated lipids
Pyelonephritis D011704 5 associated lipids
Erythema Nodosum D004893 5 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Bronchiolitis D001988 6 associated lipids
Whooping Cough D014917 6 associated lipids
Bronchitis D001991 6 associated lipids
Meningitis, Bacterial D016920 6 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Syphilis D013587 6 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Skin Ulcer D012883 6 associated lipids
Nocardia Infections D009617 6 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Plaque, Atherosclerotic D058226 7 associated lipids
Stomach Diseases D013272 7 associated lipids
Klebsiella Infections D007710 7 associated lipids
Metaplasia D008679 7 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Tooth Discoloration D014075 7 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Bacteriuria D001437 7 associated lipids
Bronchiectasis D001987 7 associated lipids
Periodontal Attachment Loss D017622 7 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Psychoses, Substance-Induced D011605 7 associated lipids
Chlamydia Infections D002690 7 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Leprosy D007918 8 associated lipids
Fistula D005402 8 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Renal Insufficiency D051437 8 associated lipids
Lymphadenitis D008199 8 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Cross Infection D003428 9 associated lipids
Urination Disorders D014555 9 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Urethritis D014526 9 associated lipids
Sinusitis D012852 9 associated lipids
Bacteremia D016470 9 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Pilotto A et al. Efficacy of 7 day lansoprazole-based triple therapy for Helicobacter pylori infection in elderly patients. 1999 J. Gastroenterol. Hepatol. pmid:10355512
Jacoby EB and Porter KB Helicobacter pylori infection and persistent hyperemesis gravidarum. 1999 Am J Perinatol pmid:10355915
Fost DA et al. Inhibition of methylprednisolone elimination in the presence of clarithromycin therapy. 1999 J. Allergy Clin. Immunol. pmid:10359882
Gooch WM et al. Loracarbef versus clarithromycin in children with acute otitis media with effusion. 1999 Clin Ther pmid:10363736
Moshkowitz M et al. The efficacy of omeprazole-based short-term triple therapy in Helicobacter pylori-positive older patients with dyspepsia. 1999 J Am Geriatr Soc pmid:10366173
Wimsatt JH et al. Clarithromycin pharmacokinetics in the desert tortoise (Gopherus agassizii). 1999 J. Zoo Wildl. Med. pmid:10367642
Iida H et al. Hypoglycemia induced by interaction between clarithromycin and disopyramide. 1999 Jpn Heart J pmid:10370402
Bhasin DK et al. Helicobacter pylori eradication: comparison of three treatment regimens in India. 1999 J. Clin. Gastroenterol. pmid:10372934
Behrens R et al. Dual versus triple therapy of Helicobacter pylori infection: results of a multicentre trial. 1999 Arch. Dis. Child. pmid:10373140
Masa K et al. Effect of clarithromycin and other macrolides on the sulfoxidation and 5-hydroxylation of lansoprazole in dogs. 1999 Biol. Pharm. Bull. pmid:10375172
Bamford JT et al. Effect of treatment of Helicobacter pylori infection on rosacea. 1999 Arch Dermatol pmid:10376693
Alvarez-Elcoro S and Enzler MJ The macrolides: erythromycin, clarithromycin, and azithromycin. 1999 Mayo Clin. Proc. pmid:10377939
Vakil N Treatment of H. pylori infection: the reality. 1998 Mar-Apr Yale J Biol Med pmid:10378357
Delle Cave M et al. Seven days of ranitidine bismuth citrate plus two antimicrobials for Helicobacter pylori eradication. 1999 Ital J Gastroenterol Hepatol pmid:10379492
Schubert ML H. pylori and nonulcer dyspepsia: not guilty as charged. 1999 Gastroenterology pmid:10381939
Realdi G et al. Pretreatment antibiotic resistance in Helicobacter pylori infection: results of three randomized controlled studies. 1999 Helicobacter pmid:10382124
Schwartz HI et al. Twice-daily versus thrice-daily clarithromycin in combination with ranitidine bismuth citrate in the eradication of Helicobacter pylori. 1999 Helicobacter pmid:10382126
Hoellman DB et al. Anti-pneumococcal activity of gatifloxacin compared with other quinolone and non-quinolone agents. 1999 J. Antimicrob. Chemother. pmid:10382885
Steele-Moore L et al. In vitro activities of clarithromycin and azithromycin against clinical isolates of Mycobacterium avium-M. intracellulare. 1999 Antimicrob. Agents Chemother. pmid:10383373
Huang J and Hunt RH The importance of clarithromycin dose in the management of Helicobacter pylori infection: a meta-analysis of triple therapies with a proton pump inhibitor, clarithromycin and amoxycillin or metronidazole. 1999 Aliment. Pharmacol. Ther. pmid:10383500