clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- FEMS Immunol. Med. Microbiol. (1)
- J. Antimicrob. Chemother. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| De Wit S et al. | Acquired resistance to clarithromycin as combined therapy in Mycobacterium avium intracellulare infection. | 1993 | Lancet | pmid:8093299 |
| Maurin M and Raoult D | In vitro susceptibilities of spotted fever group rickettsiae and Coxiella burnetti to clarithromycin. | 1993 | Antimicrob. Agents Chemother. | pmid:8109928 |
| Alba D et al. | [Clarithromycin in the treatment of cerebral toxoplasmosis associated with HIV infection]. | 1993 | Rev Clin Esp | pmid:8516514 |
| Alder J et al. | Clarithromycin therapy of experimental Treponema pallidum infections in hamsters. | 1993 | Antimicrob. Agents Chemother. | pmid:8494384 |
| Franck N et al. | Treatment of Mycobacterium chelonae-induced skin infection with clarithromycin. | 1993 | J. Am. Acad. Dermatol. | pmid:8496448 |
| Tomioka H et al. | [In vitro antimycobacterial activity of clarithromycin and its therapeutic efficacy against Mycobacterium intracellulare infection induced in mice]. | 1993 | Kekkaku | pmid:8497119 |
| Monteforte JS and Wood CA | Pneumonia caused by Nocardia nova and Aspergillus fumigatus after cardiac transplantation. | 1993 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8500477 |
| Yasuda H et al. | Interaction between biofilms formed by Pseudomonas aeruginosa and clarithromycin. | 1993 | Antimicrob. Agents Chemother. | pmid:8239580 |
| Lazard T et al. | Clarithromycin, minocycline, and rifabutin treatments before and after infection of C57BL/6 mice with Mycobacterium avium. | 1993 | Antimicrob. Agents Chemother. | pmid:8215285 |
| Helm CJ et al. | Comparison of topical antibiotics for treating Mycobacterium fortuitum keratitis in an animal model. | 1993 | Am. J. Ophthalmol. | pmid:8250072 |
| Green PA et al. | Mycobacterium avium complex parotid lymphadenitis: successful therapy with clarithromycin and ethambutol. | 1993 | Pediatr. Infect. Dis. J. | pmid:8346008 |
| Pialoux G et al. | Combination antibiotic treatment with clarithromycin for human immunodeficiency virus-associated Rhodococcus equi infection. | 1993 | Clin. Infect. Dis. | pmid:8218702 |
| Foltzer MA et al. | Bronchopulmonary bacillary angiomatosis. | 1993 | Chest | pmid:8365330 |
| Fraschini F et al. | Clarithromycin clinical pharmacokinetics. | 1993 | Clin Pharmacokinet | pmid:8222460 |
| Sedlmayr T et al. | [Clarithromycin, a new macrolide antibiotic. Effectiveness in puerperal infections and pharmacokinetics in breast milk]. | 1993 | Geburtshilfe Frauenheilkd | pmid:8370491 |
| Braga PC and Piatti G | Sub-lethal concentrations of clarithromycin interfere with the expression of Staphylococcus aureus adhesiveness to human cells. | 1993 | J Chemother | pmid:8371124 |
| Macklin JL et al. | A single-blind, randomised, comparative study of clarithromycin and amoxycillin suspensions in the treatment of children with lower respiratory tract infections. | 1993 | J Chemother | pmid:8371127 |
| Ragnaud JM et al. | [Cerebral toxoplasmosis in AIDS. 73 cases. Clinical Epidemiology Group on AIDS in Aquitania]. | 1993 | Presse Med | pmid:8378280 |
| Hoffner SE et al. | Susceptibility of Mycobacterium malmoense to antibacterial drugs and drug combinations. | 1993 | Antimicrob. Agents Chemother. | pmid:8392308 |
| Gevaudan MJ et al. | In-vitro evaluation of clarithromycin, temafloxacin, and ethambutol in combination against Mycobacterium avium complex. | 1993 | J. Antimicrob. Chemother. | pmid:8392998 |
| Wallace RJ et al. | Clinical trial of clarithromycin for cutaneous (disseminated) infection due to Mycobacterium chelonae. | 1993 | Ann. Intern. Med. | pmid:8357113 |
| Ruf B et al. | Effectiveness of the macrolide clarithromycin in the treatment of Mycobacterium avium complex infection in HIV-infected patients. | 1992 Sep-Oct | Infection | pmid:1428183 |
| Friend DR | Polyacrylate resin microcapsules for taste masking of antibiotics. | 1992 Oct-Dec | J Microencapsul | pmid:1403495 |
| de Campora E et al. | Comparative efficacy and safety of roxithromycin and clarithromycin in upper respiratory tract infections. | 1992 May-Jun | Diagn. Microbiol. Infect. Dis. | pmid:1535578 |
| Nilsen OG et al. | Macrolide pharmacokinetics and dose scheduling of roxithromycin. | 1992 May-Jun | Diagn. Microbiol. Infect. Dis. | pmid:1535579 |
| Hoover WW et al. | Clarithromycin in vitro activity enhanced by its major metabolite, 14-hydroxyclarithromycin. | 1992 Mar-Apr | Diagn. Microbiol. Infect. Dis. | pmid:1533827 |
| Chapelsky MC et al. | Renal tubular enzyme effects of clarithromycin in comparison with gentamicin and placebo in volunteers. | 1992 Jul-Aug | Drug Saf | pmid:1355971 |
| Logan RP et al. | Clarithromycin and omeprazole for Helicobacter pylori. | 1992 | Lancet | pmid:1353155 |
| Hammerschlag MR et al. | In vitro activities of azithromycin, clarithromycin, L-ofloxacin, and other antibiotics against Chlamydia pneumoniae. | 1992 | Antimicrob. Agents Chemother. | pmid:1324650 |
| Paulsen P et al. | Influence of azithromycin and other macrolides on the intracellular killing of Staphylococcus aureus by human polymorphonuclear leucocytes of healthy donors and a patient with Chédiak-Higashi syndrome. | 1992 | Chemotherapy | pmid:1324831 |
| Ruf B et al. | Acquired resistance of MAI to clarithromycin. | 1992 | Am. Rev. Respir. Dis. | pmid:1533999 |
| Berk SL | New macrolide antibiotics. | 1992 | Ann. Intern. Med. | pmid:1386966 |
| de Lalla F et al. | Clarithromycin-ciprofloxacin-amikacin for therapy of Mycobacterium avium-Mycobacterium intracellulare bacteremia in patients with AIDS. | 1992 | Antimicrob. Agents Chemother. | pmid:1387303 |
| Calzolari E et al. | The efficacy of clarythromycin (A-56268, TE-031) in the treatment of genital chlamydial infection. | 1992 | Drugs Exp Clin Res | pmid:1306155 |
| Klemens SP et al. | Activity of clarithromycin against Mycobacterium avium complex infection in beige mice. | 1992 | Antimicrob. Agents Chemother. | pmid:1336945 |
| Ji B et al. | Bactericidal activities of single or multiple doses of various combinations of new antileprosy drugs and/or rifampin against M. leprae in mice. | 1992 | Int. J. Lepr. Other Mycobact. Dis. | pmid:1338596 |
| Omura S et al. | [Research and development of clarithromycin]. | 1992 | Yakugaku Zasshi | pmid:1469609 |
| Chu SY et al. | Clarithromycin pharmacokinetics in healthy young and elderly volunteers. | 1992 | J Clin Pharmacol | pmid:1474166 |
| Gelber RH et al. | Clarithromycin at very low levels and on intermittent administration inhibits the growth of M. leprae in mice. | 1992 | Int. J. Lepr. Other Mycobact. Dis. | pmid:1474290 |
| Heifets LB et al. | Bacteriostatic and bactericidal activities of gentamicin alone and in combination with clarithromycin against Mycobacterium avium. | 1992 | Antimicrob. Agents Chemother. | pmid:1416852 |
| Brown BA et al. | Activities of clarithromycin against eight slowly growing species of nontuberculous mycobacteria, determined by using a broth microdilution MIC system. | 1992 | Antimicrob. Agents Chemother. | pmid:1416891 |
| Biehle J and Cavalieri SJ | In vitro susceptibility of Mycobacterium kansasii to clarithromycin. | 1992 | Antimicrob. Agents Chemother. | pmid:1416897 |
| Chu SY et al. | Pharmacokinetics of clarithromycin, a new macrolide, after single ascending oral doses. | 1992 | Antimicrob. Agents Chemother. | pmid:1489187 |
| Araujo FG et al. | Activity of clarithromycin alone or in combination with other drugs for treatment of murine toxoplasmosis. | 1992 | Antimicrob. Agents Chemother. | pmid:1489188 |
| Gan VN et al. | Pharmacokinetics of a clarithromycin suspension in infants and children. | 1992 | Antimicrob. Agents Chemother. | pmid:1489191 |
| Sturgill MG and Rapp RP | Clarithromycin: review of a new macrolide antibiotic with improved microbiologic spectrum and favorable pharmacokinetic and adverse effect profiles. | 1992 | Ann Pharmacother | pmid:1421677 |
| Denny FW | Current management of streptococcal pharyngitis. | 1992 | J Fam Pract | pmid:1453145 |
| Schrock CG | Clarithromycin vs penicillin in the treatment of streptococcal pharyngitis. | 1992 | J Fam Pract | pmid:1453146 |
| Chaisson R | Clarithromycin is effective against M. avium complex in AIDS. | 1992 | Am Fam Physician | pmid:1456199 |
| Ji B et al. | Selection of resistant mutants of Mycobacterium avium in beige mice by clarithromycin monotherapy. | 1992 | Antimicrob. Agents Chemother. | pmid:1482155 |