clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Granda MartÃn MJ et al. | [Mycoplasma-associated acute hepatitis in an adult patient without pulmonary involvement]. | Gastroenterol Hepatol | pmid:24569138 | |
Di Mario F et al. | Use of lactoferrin for Helicobacter pylori eradication. Preliminary results. | J. Clin. Gastroenterol. | pmid:12702979 | |
Alsohaibani F et al. | Prospective trial in Saudi Arabia comparing the 14-day standard triple therapy with the 10-day sequential therapy for treatment of Helicobacter pylori infection. | Saudi J Gastroenterol | pmid:26228365 | |
Agha Z et al. | Is antibiotic prophylaxis for bacterial endocarditis cost-effective? | Med Decis Making | pmid:15951458 | |
Kekilli M et al. | Inefficacy of triple therapy and comparison of two different bismuth-containing quadruple regimens as a firstline treatment option for helicobacter pylori. | Saudi J Gastroenterol | pmid:27748322 | |
Ikeda H et al. | Severe Disseminated Mycobacterium avium Infection in a Patient with a Positive Serum Autoantibody to Interferon-γ. | Intern. Med. | pmid:27746449 | |
Ubhayawardana NL et al. | Detection of clarithromycin-resistant Helicobacter pylori strains in a dyspeptic patient population in Sri Lanka by polymerase chain reaction-restriction fragment length polymorphism. | Indian J Med Microbiol | pmid:26068338 | |
Set R and Shastri J | Laboratory aspects of clinically significant rapidly growing mycobacteria. | Indian J Med Microbiol | pmid:22120792 | |
Aoki D et al. | Roxithromycin inhibits angiogenesis of human hepatoma cells in vivo by suppressing VEGF production. | Anticancer Res. | pmid:15816530 | |
Kim HY et al. | Allele-specific duplex polymerase chain reaction to differentiate Mycobacterium abscessus subspecies and to detect highly clarithromycin-resistant isolates. | Indian J Med Microbiol | pmid:27514964 | |
Yang X et al. | Comparison Between Sequential Therapy and Modified Bismuth-Included Quadruple Therapy for Helicobacter pylori Eradication in Chinese Patients. | Am J Ther | pmid:25923229 | |
Mégraud F | [Helicobacter pylori infection: Review and practice]. | Presse Med | pmid:20627443 | |
Vicente R et al. | [Helicobacter pylori eradication in patients with peptic ulcer after two treatment failures: a prospective culture-guided study]. | Gastroenterol Hepatol | pmid:12139836 | |
Yoon HJ et al. | Nontuberculous mycobacterial tenosynovitis in the hand: two case reports with the MR imaging findings. | Korean J Radiol | pmid:22043158 | |
Wang B et al. | In-vitro characterisation of a novel antimicrobial agent, TNP-2092, against Helicobacter pylori clinical isolates. | Swiss Med Wkly | pmid:30044468 | |
Lage R et al. | Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease. | An Bras Dermatol | pmid:25672306 | |
Horiguchi T et al. | Antibacterial activity and clinical efficacy of sparfloxacin in Mycobacterium avium-intracellulare complex infection. | J. Int. Med. Res. | pmid:15458286 | |
Solé López J et al. | [Consumption of antibiotics and their possible relationship with bacterial resistance in the "Costa de Ponent" health region: analysis of evolution through the initial and end periods of the last decade]. | Aten Primaria | pmid:15274900 | |
Issa H et al. | Bleeding duodenal ulcer after Roux-en-Y gastric bypass surgery: the value of laparoscopic gastroduodenoscopy. | Ann Saudi Med | pmid:20103961 | |
Mishra A et al. | A rare debilitating neurological adverse effect of ranolazine due to drug interaction with clarithromycin. | Indian J Pharmacol | pmid:25298587 | |
Lew EA | Clarithromycin, lansoprazole, and metronidazole eradicated Helicobacter pylori infection in chronic renal insufficiency. | ACP J. Club | pmid:15122860 | |
Beck J | Efficacy of esomeprazole in patients with acid-peptic disorders. | Gastroenterol Nurs | pmid:15082946 | |
Torpiano P and Pace D | Clinically-diagnosed Mediterranean Spotted Fever in Malta. | Travel Med Infect Dis | pmid:29462726 | |
Cohen ND et al. | Use of Liposomal Gentamicin for Treatment of 5 Foals with Experimentally Induced Rhodococcus equi Pneumonia. | J. Vet. Intern. Med. | pmid:26692327 | |
Varghese B et al. | First case report of chronic pulmonary lung disease caused by Mycobacterium abscessus in two immunocompetent patients in Saudi Arabia. | Ann Saudi Med | pmid:22588446 | |
Liang CM et al. | Levofloxacin-containing second-line anti-Helicobacter pylori eradication in Taiwanese real-world practice. | Biomed J | pmid:25163495 | |
Wang J et al. | Two-week triple therapy has a higher Helicobacter pylori eradication rate than 1-week therapy: A single-center randomized study. | Saudi J Gastroenterol | pmid:26655129 | |
Pellicano R and Fagoonee S | One or two weeks of treatment with Helicobacter Pylori ''standard'' triple therapy in the year 2015? | Saudi J Gastroenterol | pmid:26655127 | |
Bernstein JM and Bacheller CD | It's on the tip of my tongue. | Skinmed | pmid:16687984 | |
Moreira C et al. | Symmetrical drug-related intertriginous and flexural exanthema induced by clarithromycin. | An Bras Dermatol | pmid:28954125 | |
Rush R and Sheth S | Fulminant toxoplasmic retinochoroiditis following intravitreal triamcinolone administration. | Indian J Ophthalmol | pmid:22446913 | |
Seitz CS et al. | Suspicion of macrolide allergy after treatment of infectious diseases including Helicobacter pylori: results of allergological testing. | Allergol Immunopathol (Madr) | pmid:21269750 | |
Doorakkers E et al. | Helicobacter pylori eradication in the Swedish population. | Scand. J. Gastroenterol. | pmid:28323552 | |
Cobos-Trigueros N et al. | [Macrolides and ketolides]. | Enferm. Infecc. Microbiol. Clin. | pmid:19625112 | |
Vaishnav P and Demain AL | Unexpected applications of secondary metabolites. | Biotechnol. Adv. | pmid:21130862 | |
Radzikowska E et al. | Clarithromycin Decreases IL-6 Concentration in Serum and BAL Fluid in Patients with Cryptogenic Organizing Pneumonia. | Adv Clin Exp Med | pmid:28028949 |