clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Castro-Silva AN et al. | Cutaneous Mycobacterium haemophilum infection in a kidney transplant recipient after acupuncture treatment. | 2011 | Transpl Infect Dis | pmid:20534038 |
Baluch A et al. | Successful management of Mycobacterium haemophilum lower extremity cutaneous infection in a matched-unrelated donor stem cell transplant recipient. | 2017 | Transpl Infect Dis | pmid:27775824 |
Ho TA et al. | Nontuberculous mycobacterial pulmonary infection in renal transplant recipients. | 2010 | Transpl Infect Dis | pmid:19929882 |
Lyons J et al. | An unusual lung mass post stem cell transplantation. | 2014 | Transpl Infect Dis | pmid:24995624 |
Lu KJ et al. | Mycobacterium genavense duodenitis following allogeneic peripheral blood stem cell transplantation. | 2009 | Transpl Infect Dis | pmid:19656345 |
Pea F et al. | Everolimus overexposure in a heart transplant patient receiving clarithromycin for the treatment of pneumonia. | 2015 | Transpl Infect Dis | pmid:26296391 |
de Jong JJ et al. | Atypical mycobacterium infection with dermatological manifestation in a renal transplant recipient. | 1999 | Transpl. Int. | pmid:10080410 |
Morales P et al. | Successful recovery after disseminated infection due to mycobacterium abscessus in a lung transplant patient: subcutaneous nodule as first manifestation--a case report. | 2007 | Transplant. Proc. | pmid:17889205 |
Sezer S et al. | Association of helicobacter pylori infection with nutritional status in hemodialysis patients. | 2004 Jan-Feb | Transplant. Proc. | pmid:15013297 |
Qvist T et al. | First report of lung transplantation in a patient with active pulmonary Mycobacterium simiae infection. | 2013 | Transplant. Proc. | pmid:23267789 |
Fujiwara T et al. | Helicobacter pylori infection in renal transplant recipients. | 2000 | Transplant. Proc. | pmid:11120026 |
Bhaloo S and Prasad GV | Severe reduction in tacrolimus levels with rifampin despite multiple cytochrome P450 inhibitors: a case report. | 2003 | Transplant. Proc. | pmid:14611983 |
Lasmar EP et al. | Mucosa-associated lymphoid tissue gastric lymphoma regression in a renal transplant patient after conversion of the immunosuppression to sirolimus: a case report. | 2009 | Transplant. Proc. | pmid:19376398 |
Freudenberger RS and Simafranca SM | Cutaneous infection with rapidly-growing mycobacterial infection following heart transplant: a case report and review of the literature. | 2006 | Transplant. Proc. | pmid:16797350 |
Ogawa M et al. | Matrix metalloproteinase suppression induced by clarithromycin in murine cardiac allografts. | 2009 Jan-Feb | Transplant. Proc. | pmid:19249565 |
Gómez G et al. | Acute tacrolimus nephrotoxicity in renal transplant patients treated with clarithromycin. | 1999 | Transplant. Proc. | pmid:10500563 |
Tokgöz B et al. | Effects of azithromycin on cyclosporine-induced gingival hyperplasia in renal transplant patients. | 2004 | Transplant. Proc. | pmid:15621128 |
Naik S et al. | Successful treatment of Nocardia nova bacteremia and multilobar pneumonia with clarithromycin in a heart transplant patient. | 2007 | Transplant. Proc. | pmid:17580232 |
Benden C and Boehler A | Long-term clarithromycin therapy in the management of lung transplant recipients. | 2009 | Transplantation | pmid:19461491 |
Ferrari SL et al. | The interaction between clarithromycin and cyclosporine in kidney transplant recipients. | 1994 | Transplantation | pmid:7940695 |