clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Takagi M et al. | Underlying mechanism of drug-drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8. | 2015 | Drug Metab. Pharmacokinet. | pmid:26195223 |
| Li Y et al. | Liposomal co-delivery of daptomycin and clarithromycin at an optimized ratio for treatment of methicillin-resistant Staphylococcus aureus infection. | 2015 | Drug Deliv | pmid:24471983 |
| Antony SJ | Catheter related line sepsis resulting from Mycobacterium chelonae infection in an immunocompromised host. | 2015 | Infect Disord Drug Targets | pmid:26205798 |
| Chowdhary M et al. | Intracranial abscess due to Mycobacterium avium complex in an immunocompetent host: a case report. | 2015 | BMC Infect. Dis. | pmid:26201464 |
| Zheng H et al. | Association of the in vitro susceptibility of clinical isolates of chlamydia trachomatis with serovar and duration of antibiotic exposure. | 2015 | Sex Transm Dis | pmid:25668641 |
| Jung IY et al. | A case of bronchiolitis obliterans organizing pneumonia in an HIV-infected Korean patient successfully treated with clarithromycin. | 2015 | BMC Infect. Dis. | pmid:26201392 |
| Sobajima T et al. | A Case of Pulmonary Actinomycosis Associated With Aspiration of Cedar Leaves. | 2015 | J Bronchology Interv Pulmonol | pmid:26165898 |
| Gunjan S et al. | Clarithromycin enhances the antimalarial efficacy of mefloquine via its increased bioavailability and disrupting P. falciparum apicoplast. | 2015 | Life Sci. | pmid:26164186 |
| Tongtawee T et al. | Effect of Pretreatment with Lactobacillus delbrueckii and Streptococcus thermophillus on Tailored Triple Therapy for Helicobacter pylori Eradication: A Prospective Randomized Controlled Clinical Trial. | 2015 | Asian Pac. J. Cancer Prev. | pmid:26163609 |
| Fujimura S et al. | Antimicrobial efficacy of combined clarithromycin plus daptomycin against biofilms-formed methicillin-resistant Staphylococcus aureus on titanium medical devices. | 2015 | J. Infect. Chemother. | pmid:26162777 |
| Cavkaytar S et al. | Clarithromycin regresses endometriotic implants in rat endometriosis model. | 2015 | J Obstet Gynaecol | pmid:26156575 |
| Bai P et al. | Susceptibility of Helicobacter pylori to antibiotics in Chinese patients. | 2015 | J Dig Dis | pmid:26147515 |
| Fujiki S et al. | Suppressed Release of Clarithromycin from Tablets by Crystalline Phase Transition of Metastable Polymorph Form I. | 2015 | J Pharm Sci | pmid:26053058 |
| Zeng M et al. | Clarithromycin and dexamethasone show similar anti-inflammatory effects on distinct phenotypic chronic rhinosinusitis: an explant model study. | 2015 | BMC Immunol. | pmid:26047816 |
| Converse PJ et al. | Efficacy of Rifampin Plus Clofazimine in a Murine Model of Mycobacterium ulcerans Disease. | 2015 | PLoS Negl Trop Dis | pmid:26042792 |
| Klain V and Timmerman L | Comment on The dangers of gastritis: a case of clarithromycin-associated brief psychotic episode. | 2015 | J. Nerv. Ment. Dis. | pmid:26034875 |
| Prapitpaiboon H et al. | High Efficacy of Levofloxacin-Dexlansoprazole-Based Quadruple Therapy as a First Line Treatment for Helicobacter pylori Eradication in Thailand. | 2015 | Asian Pac. J. Cancer Prev. | pmid:26028098 |
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| Rose SJ et al. | Mycobacterium avium Possesses Extracellular DNA that Contributes to Biofilm Formation, Structural Integrity, and Tolerance to Antibiotics. | 2015 | PLoS ONE | pmid:26010725 |
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| Cowan R et al. | Mycobacterium ulcerans treatment--can antibiotic duration be reduced in selected patients? | 2015 | PLoS Negl Trop Dis | pmid:25658304 |
| Brown-Elliott BA et al. | Utility of sequencing the erm(41) gene in isolates of Mycobacterium abscessus subsp. abscessus with low and intermediate clarithromycin MICs. | 2015 | J. Clin. Microbiol. | pmid:25653399 |
| Iino Y et al. | Clinical effects of clarithromycin on persistent inflammation following Haemophilus influenzae-positive acute otitis media. | 2015 | Acta Otolaryngol. | pmid:25649881 |
| Streetman DS and Stout SM | Is there a clinically relevant interaction between clarithromycin and statins not metabolized by cytochrome P450 3A4? | 2015 | CMAJ | pmid:25646282 |
| Ang TL et al. | Ten-day triple therapy versus sequential therapy versus concomitant therapy as first-line treatment for Helicobacter pylori infection. | 2015 | J. Gastroenterol. Hepatol. | pmid:25639278 |
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| Kam Y et al. | Sweat but no gain: inhibiting proliferation of multidrug resistant cancer cells with "ersatzdroges". | 2015 | Int. J. Cancer | pmid:25156304 |
| Yildizoglu U et al. | Effect of antibiotic use on bacterial flora of tonsil core in patients with recurrent tonsillitis. | 2015 | Eur Arch Otorhinolaryngol | pmid:25510984 |
| Jiang F et al. | The influences of CYP2D6 genotypes and drug interactions on the pharmacokinetics of venlafaxine: exploring predictive biomarkers for treatment outcomes. | 2015 | Psychopharmacology (Berl.) | pmid:25510856 |
| Kim H et al. | Efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenia patients with moderate thrombocytopenia. | 2015 | Ann. Hematol. | pmid:25501820 |
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| Bang CS et al. | Additive Effect of Pronase on the Eradication Rate of First-Line Therapy for Helicobacter pylori Infection. | 2015 | Gut Liver | pmid:25167799 |
| Keshavarz Azizi Raftar S et al. | The Helicobacter pylori resistance rate to clarithromycin in Iran. | 2015 | Microb. Drug Resist. | pmid:25144338 |
| Stepney R et al. | Case report: Improved gum health. | 2015 | Br Dent J | pmid:26657423 |
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| Hsu PI et al. | A Randomized Controlled Study Comparing Reverse Hybrid Therapy and Standard Triple Therapy for Helicobacter pylori Infection. | 2015 | Medicine (Baltimore) | pmid:26632893 |
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| Mesgarpour B et al. | A population-based analysis of the risk of drug interaction between clarithromycin and statins for hospitalisation or death. | 2015 | Lipids Health Dis | pmid:26497728 |
| Namkoong H et al. | Successful resumption of tocilizumab for rheumatoid arthritis after resection of a pulmonary Mycobacterium avium complex lesion: a case report. | 2015 | BMC Pulm Med | pmid:26496968 |
| Wang CH et al. | Effects of daily telephone-based re-education before taking medicine on Helicobacter pylori eradication: A prospective single-center study from China. | 2015 | World J. Gastroenterol. | pmid:26494972 |
| Buch T and Andersen SE | [Combination therapy with fluconazole and other QTc-prolonging drugs increase the QTc interval]. | 2015 | Ugeskr. Laeg. | pmid:26471025 |
| Kiesewetter B et al. | Clarithromycin Leading to Complete Remission in the First-Line Treatment of Ocular Adnexal Mucosa-Associated Lymphoid Tissue Lymphoma. | 2015 | J. Clin. Oncol. | pmid:24778391 |
| Yin SM et al. | Disseminated Mycobacterium kansasii disease in complete DiGeorge syndrome. | 2015 | J. Clin. Immunol. | pmid:26048260 |
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| Nakamura M et al. | Clarithromycin ameliorates pulmonary inflammation induced by short term cigarette smoke exposure in mice. | 2015 | Pulm Pharmacol Ther | pmid:26363279 |
| Zhang W et al. | Bismuth, lansoprazole, amoxicillin and metronidazole or clarithromycin as first-line Helicobacter pylori therapy. | 2015 | Gut | pmid:26338726 |
| Fasciana T et al. | Resistance to clarithromycin and genotypes in Helicobacter pylori strains isolated in Sicily. | 2015 | J. Med. Microbiol. | pmid:26338221 |
| Curth HM et al. | Effects of Helicobacter pylori Eradication in Chronic Spontaneous Urticaria: Results from a Retrospective Cohort Study. | 2015 | Am J Clin Dermatol | pmid:26334425 |
| Brusselle GG | Are the antimicrobial properties of macrolides required for their therapeutic efficacy in chronic neutrophilic airway diseases? | 2015 | Thorax | pmid:25870311 |
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| Velu PP et al. | Pulmonary Mycobacterium marinum infection: 'fish tank granuloma' of the lung. | 2016 | Scott Med J | pmid:27872397 |
| Noh HM et al. | Eradication Rate by Duration of Third-line Rescue Therapy with Levofloxacin after Helicobacter pylori Treatment Failure in Clinical Practice. | 2016 | Korean J Gastroenterol | pmid:27871162 |
| Yazdanbakhsh AR et al. | Reduction of non-Betalactam Antibiotics COD by Combined Coagulation and Advanced Oxidation Processes. | 2016 | Water Environ. Res. | pmid:28661328 |
| Sancak S et al. | Intestinal blood flow by Doppler ultrasound: the impact of clarithromycin treatment for feeding intolerance in preterm neonates. | 2016 | J. Matern. Fetal. Neonatal. Med. | pmid:26135789 |
| Ohe M et al. | A case of lupus nephritis treated with clarithromycin, tacrolimus, and glucocorticoids. | 2016 | Kaohsiung J. Med. Sci. | pmid:27638410 |
| Cosme A et al. | Antimicrobial Susceptibility-Guided Therapy Versus Empirical Concomitant Therapy for Eradication of Helicobacter pylori in a Region with High Rate of Clarithromycin Resistance. | 2016 | Helicobacter | pmid:25982426 |
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| Furuta K et al. | 18 Cases of pulmonary Mycobacterium abscessus: Clinical difference depending on the presence or absence of Mycobacterium avium complex. | 2016 | J. Infect. Chemother. | pmid:27430867 |
| Zemali N et al. | Helicobacter pylori resistance to clarithromycin in Reunion Island. | 2016 | Med Mal Infect | pmid:27427280 |
| Ozeki K et al. | Association of Hay Fever with the Failure of Helicobacter pylori Primary Eradication. | 2016 | Intern. Med. | pmid:27374672 |
| Campillo A et al. | [Cuadruple concomitant non-bismuth therapy vs. classical triple therapy as first line therapy for Helicobacter pylori infection]. | 2016 | Med Clin (Barc) | pmid:27374029 |
| Garcia de Carvalho NF et al. | Resazurin Microtiter Assay for Clarithromycin Susceptibility Testing of Clinical Isolates of Mycobacterium abscessus Group. | 2016 | J. Clin. Lab. Anal. | pmid:27169515 |
| Schuster S et al. | Evidence of a Substrate-Discriminating Entrance Channel in the Lower Porter Domain of the Multidrug Resistance Efflux Pump AcrB. | 2016 | Antimicrob. Agents Chemother. | pmid:27161641 |
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| Mayor S | Short term increase in neuropsychiatric events is seen with H pylori treatment containing clarithromycin. | 2016 | BMJ | pmid:27143325 |
| Li M et al. | Inducible Expression of both ermB and ermT Conferred High Macrolide Resistance in Streptococcus gallolyticus subsp. pasteurianus Isolates in China. | 2016 | Int J Mol Sci | pmid:27669217 |
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| Radzikowska E et al. | Cryptogenic Organizing Pneumonia: IL-1β, IL-6, IL-8, and TGF- β1 Serum Concentrations and Response to Clarithromycin Treatment. | 2016 | Adv. Exp. Med. Biol. | pmid:26987326 |
| Wu DC et al. | A Pilot Randomized Controlled Study of Dexlansoprazole MR-Based Triple Therapy for Helicobacter Pylori Infection. | 2016 | Medicine (Baltimore) | pmid:26986096 |
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| Todo K et al. | Severe Helicobacter pylori gastritis-related thrombocytopenia and iron deficiency anemia in an adolescent female. | 2016 | Ann. Hematol. | pmid:26957356 |
| Kadota T et al. | Analysis of drug treatment outcome in clarithromycin-resistant Mycobacterium avium complex lung disease. | 2016 | BMC Infect. Dis. | pmid:26818764 |
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| Fralick M et al. | Bleeding associated with coadministration of rivaroxaban and clarithromycin. | 2016 | CMAJ | pmid:26811362 |
| Berlin S et al. | Pharmacokinetics and Pulmonary Distribution of Clarithromycin and Rifampicin after Concomitant and Consecutive Administration in Foals. | 2016 | Mol. Pharm. | pmid:26808255 |
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| Geng S et al. | Clarithromycin ion pair in a liposomal membrane to improve its stability and reduce its irritation caused by intravenous administration. | 2016 | Expert Opin Drug Deliv | pmid:26588710 |
| Eszik I et al. | High dynamic range detection of Chlamydia trachomatis growth by direct quantitative PCR of the infected cells. | 2016 | J. Microbiol. Methods | pmid:26578244 |
| Jain SK et al. | Lectin-Conjugated Clarithromycin and Acetohydroxamic Acid-Loaded PLGA Nanoparticles: a Novel Approach for Effective Treatment of H. pylori. | 2016 | AAPS PharmSciTech | pmid:26566630 |
| Chen CH et al. | Mycobacterium abscessus complex bacteremia due to prostatitis after prostate biopsy. | 2016 | Indian J Tuberc | pmid:27998503 |
| Gehlot V et al. | Low prevalence of clarithromycin-resistant Helicobacter pylori isolates with A2143G point mutation in the 23S rRNA gene in North India. | 2016 | J Glob Antimicrob Resist | pmid:27530837 |
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