| MeSH term | MeSH ID | Detail |
|---|---|---|
| Proteinuria | D011507 | 30 associated lipids |
| Endometriosis | D004715 | 29 associated lipids |
| Angina Pectoris | D000787 | 27 associated lipids |
| Gastritis | D005756 | 27 associated lipids |
| Gastrointestinal Hemorrhage | D006471 | 27 associated lipids |
| Nasal Polyps | D009298 | 26 associated lipids |
| Pseudomonas Infections | D011552 | 25 associated lipids |
| Genetic Predisposition to Disease | D020022 | 24 associated lipids |
| Cardiovascular Diseases | D002318 | 24 associated lipids |
| Stomach Neoplasms | D013274 | 24 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- Clin. Infect. Dis. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jaup BH and Norrby A | Low dose, short-term triple therapy for cure of Helicobacter pylori infection and healing of peptic ulcers. | 1995 | Am. J. Gastroenterol. | pmid:7771426 |
| Musher DM | Clarithromycin therapy for Mycobacterium avium complex bacteremia. | 1995 | Ann. Intern. Med. | pmid:7778830 |
| van der Meer JT and Danner SA | Clarithromycin therapy for Mycobacterium avium complex bacteremia. | 1995 | Ann. Intern. Med. | pmid:7778831 |
| Burette A and Glupczynski Y | Helicobacter pylori: the place of the new macrolides in the eradication of the bacteria in peptic ulcer disease. | 1995 | Infection | pmid:7782116 |
| Odenholt-Tornqvist I et al. | Postantibiotic effects and postantibiotic sub-MIC effects of roxithromycin, clarithromycin, and azithromycin on respiratory tract pathogens. | 1995 | Antimicrob. Agents Chemother. | pmid:7695310 |
| Ives DV et al. | Impact of clarithromycin and azithromycin on patterns of treatment and survival among AIDS patients with disseminated Mycobacterium avium complex. | 1995 | AIDS | pmid:7755914 |
| Klapper SR et al. | Atypical mycobacterial infection of the orbit. | 1995 | Ophthalmology | pmid:9097803 |
| Odagiri S | Levofloxacin in patients with severe respiratory tract infection. | 1995 | Drugs | pmid:8549387 |
| Logan RP et al. | Eradication of Helicobacter pylori and prevention of recurrence of duodenal ulcer: a randomized, double-blind, multi-centre trial of omeprazole with or without clarithromycin. | 1995 | Aliment. Pharmacol. Ther. | pmid:8527618 |
| Gill CJ et al. | In vivo evaluation of three acid-stable azalide compounds, L-701,677, L-708,299 and L-708,365 compared to erythromycin, azithromycin and clarithromycin. | 1995 | J. Antibiot. | pmid:7490222 |
| Adamek RJ et al. | [Short-term triple therapy with pantoprazole, clarithromycin and metronidazole for the healing of Helicobacter pylori infection]. | 1995 | Dtsch. Med. Wochenschr. | pmid:7889816 |
| Spangler SK et al. | Susceptibilities of 201 anaerobes to erythromycin, azithromycin, clarithromycin, and roxithromycin by oxyrase agar dilution and E test methodologies. | 1995 | J. Clin. Microbiol. | pmid:7615756 |
| Colizza DF | Pertussis update. | 1995 | J Sch Health | pmid:7637337 |
| de Boer WA and Tytgat GN | The best therapy for Helicobacter pylori infection: should efficacy or side-effect profile determine our choice? | 1995 | Scand. J. Gastroenterol. | pmid:7638563 |
| Takimoto T et al. | Efficacy of lansoprazole in eradication of Helicobacter pylori. | 1995 | J. Clin. Gastroenterol. | pmid:7594327 |
| Shimoyama T et al. | Eradication of Helicobacter pylori with lansoprazole and clarithromycin in gastric ulcer patients. | 1995 | J. Clin. Gastroenterol. | pmid:7594328 |
| Fukuda Y et al. | Combination therapies with a proton pump inhibitor for Helicobacter pylori-infected gastric ulcer patients. | 1995 | J. Clin. Gastroenterol. | pmid:7594330 |
| Xu G et al. | [Effect of clarithromycin on macrophage functions]. | 1995 | Kansenshogaku Zasshi | pmid:7594777 |
| Gelber RH et al. | Activity of combinations of dapsone, rifampin, minocycline, clarithromycin, and sparfloxacin against M. leprae-infected mice. | 1995 | Int. J. Lepr. Other Mycobact. Dis. | pmid:7602221 |
| Milde P et al. | Cutaneous bacillary angiomatosis in a patient with chronic lymphocytic leukemia. | 1995 | Arch Dermatol | pmid:7543264 |
| Nightingale SD et al. | Clarithromycin-induced mania in two patients with AIDS. | 1995 | Clin. Infect. Dis. | pmid:7548513 |
| Matsiota-Bernard P et al. | Mycobacterium genavense infection in a patient with AIDS who was successfully treated with clarithromycin. | 1995 | Clin. Infect. Dis. | pmid:7548515 |
| Citron DM et al. | Activity of ampicillin/sulbactam, ticarcillin/clavulanate, clarithromycin, and eleven other antimicrobial agents against anaerobic bacteria isolated from infections in children. | 1995 | Clin. Infect. Dis. | pmid:7548597 |
| Tamaoki J et al. | Effects of macrolide antibiotics on neurally mediated contraction of human isolated bronchus. | 1995 | J. Allergy Clin. Immunol. | pmid:7722166 |
| Conte JE et al. | Intrapulmonary pharmacokinetics of clarithromycin and of erythromycin. | 1995 | Antimicrob. Agents Chemother. | pmid:7726492 |
| Pollak PT et al. | Delirium probably induced by clarithromycin in a patient receiving fluoxetine. | 1995 | Ann Pharmacother | pmid:7655131 |
| Ozmen MM and Johnson CD | Is short-term triple therapy with lansoprazole, clarithromycin, and metronidazole a definitive answer for Helicobacter pylori eradication? | 1995 | Am. J. Gastroenterol. | pmid:7661197 |
| Savarino V et al. | New insight in the mechanism of omeprazole antimicrobial combinations to eradicate Helicobacter pylori. | 1995 | Am. J. Gastroenterol. | pmid:7717343 |
| Saito H et al. | Therapeutic effect of KRM-1648 with various antimicrobials against Mycobacterium avium complex infection in mice. | 1995 | Tuber. Lung Dis. | pmid:7718848 |
| Hedenmo M and Eriksson BM | Liquid chromatographic determination of the macrolide antibiotics roxithromycin and clarithromycin in plasma by automated solid-phase extraction and electrochemical detection. | 1995 | J Chromatogr A | pmid:7719451 |
| Schlossberg D | Azithromycin and clarithromycin. | 1995 | Med. Clin. North Am. | pmid:7791424 |
| Frotz H et al. | [Ranitidine and clarithromycin for eradication of Helicobacter pylori in patients with duodenal ulcer]. | 1995 | Arzneimittelforschung | pmid:7710445 |
| Luna-Herrera J et al. | Antituberculosis activity of clarithromycin. | 1995 | Antimicrob. Agents Chemother. | pmid:8593004 |
| Ellis LC et al. | Postantibiotic effect of clarithromycin alone and combined with ethambutol against Mycobacterium avium complex. | 1995 | Antimicrob. Agents Chemother. | pmid:8593025 |
| Truffot-Pernot C et al. | Clarithromycin is inactive against Mycobacterium tuberculosis. | 1995 | Antimicrob. Agents Chemother. | pmid:8593032 |
| Schütze K and Hentschel E | Duodenal ulcer healing after 7-day treatment: a pilot study with lansoprazole, amoxicillin and clarithromycin. | 1995 | Z Gastroenterol | pmid:8600661 |
| Tseng AL and Walmsley SL | Rifabutin-associated uveitis. | 1995 | Ann Pharmacother | pmid:8573961 |
| Rizzato G et al. | Efficacy of a three day course of azithromycin in moderately severe community-acquired pneumonia. | 1995 | Eur. Respir. J. | pmid:7789484 |
| Stafstrom CE et al. | Erythromycin-induced carbamazepine toxicity: a continuing problem. | 1995 | Arch Pediatr Adolesc Med | pmid:7827672 |
| Reid R et al. | Pneumococcal meningitis during therapy of otitis media with clarithromycin. | 1995 | Pediatr. Infect. Dis. J. | pmid:8786899 |
| Van Asselt GJ et al. | Susceptibility of Streptococcus pyogenes to azithromycin, clarithromycin, erythromycin and roxithromycin in vitro. | 1995 | J. Med. Microbiol. | pmid:7563004 |
| Cheng B | Preventing opportunistic infections. | 1995 | PI Perspect | pmid:11362422 |
| Abbott files SNDA for MAC prophylaxis. | 1995 | J Int Assoc Physicians AIDS Care | pmid:11362606 | |
| Pierce M | Another perspective on MAC prophylaxis. Interview by Gordon Nary. | 1995 | J Int Assoc Physicians AIDS Care | pmid:11362746 |
| Archange YR et al. | Clarithromycin prophylaxis against disseminated Mycobacterium avium complex in patients with AIDS. | 1995 | J Int Assoc Physicians AIDS Care | pmid:11362747 |
| Physician's aggressive preventive therapy differs. | 1995 | AIDS Alert | pmid:11362774 | |
| New drug applications sought. | 1995 | AIDS Alert | pmid:11362777 | |
| Smart T | Cryptosporidiosis at ICAAC. | 1995 | GMHC Treat Issues | pmid:11362913 |
| Claussen DW | The most commonly prescribed medications in the United States: Part 3. | 1995 Jul-Aug | Gastroenterol Nurs | pmid:7654815 |
| Hashisaki GT | Update on macrolide antibiotics. | 1995 May-Jun | Am J Otolaryngol | pmid:7661309 |
| Kees F et al. | Serum and cellular pharmacokinetics of clarithromycin 500 mg q.d. and 250 mg b.i.d. in volunteers. | 1995 May-Jun | Infection | pmid:7499006 |
| Sternon J et al. | Azithromycin compared with clarithromycin in the treatment of adult patients with acute purulent tracheobronchitis: a cost of illness study. | 1995 Nov-Dec | J. Int. Med. Res. | pmid:8746608 |
| Stein GE et al. | A preliminary study of clarithromycin versus doxycycline in the treatment of nongonococcal urethritis and mucopurulent cervicitis. | 1995 Nov-Dec | Pharmacotherapy | pmid:8602379 |
| Dalston MO et al. | [Clarithromycin combined with pyrimethamine in cerebral toxoplasmosis--a report of 2 cases]. | 1995 Oct-Dec | Rev. Soc. Bras. Med. Trop. | pmid:8668843 |
| Pinzani V et al. | [Occurrence of anterior uveitis in a HIV patient treated with rifabutin, ethambutol, clarithromycin]. | 1995 Sep-Oct | Therapie | pmid:8571297 |
| Young A | Hold the big MAC. | 1996 | Notes Undergr | pmid:11363450 |
| High-dose clarithromycin should be avoided. | 1996 | AIDS Alert | pmid:11363723 | |
| Pot shots. | 1996 | Notes Undergr | pmid:11363915 | |
| Bowersox J | CPCRA researchers present OI studies at Vancouver. | 1996 | NIAID AIDS Agenda | pmid:11363924 |
| MAC management. | 1996 | PI Perspect | pmid:11363967 | |
| Gillum JG et al. | Effect of clarithromycin on the pharmacokinetics of 2',3'-dideoxyinosine in patients who are seropositive for human immunodeficiency virus. | 1996 | Clin. Infect. Dis. | pmid:8729217 |
| Segreti J et al. | In vitro activity of macrolides against intracellular Legionella pneumophila. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8902407 |
| Dalla Libera M et al. | High effectiveness and safety of one-week antibiotic regimen in Helicobacter pylori eradication. | 1996 | Aliment. Pharmacol. Ther. | pmid:8730251 |
| Labenz J et al. | One-week triple therapy with omeprazole, amoxycillin and either clarithromycin or metronidazole for cure of Helicobacter pylori infection. | 1996 | Aliment. Pharmacol. Ther. | pmid:8730252 |
| Apseloff G et al. | Severe neutropenia caused by recommended prophylactic doses of rifabutin. | 1996 | Lancet | pmid:8782773 |
| Pankuch GA et al. | MIC and time-kill study of antipneumococcal activities of RPR 106972 (a new oral streptogramin), RP 59500 (quinupristin-dalfopristin), pyostacine (RP 7293), penicillin G, cefotaxime, erythromycin, and clarithromycin against 10 penicillin-susceptible and -resistant pneumococci. | 1996 | Antimicrob. Agents Chemother. | pmid:8878583 |
| Cadranel JF et al. | [Acute symptomatic cytolytic hepatitis probably related to clarithromycin]. | 1996 | Gastroenterol. Clin. Biol. | pmid:9119179 |
| Ednie LM et al. | Comparative activities of clarithromycin, erythromycin, and azithromycin against penicillin-susceptible and penicillin-resistant pneumococci. | 1996 | Antimicrob. Agents Chemother. | pmid:8843313 |
| Labenz J | [Helicobacter pylori eradication: finally clarity]. | 1996 | Leber Magen Darm | pmid:9082109 |
| Conte JE et al. | Single-dose intrapulmonary pharmacokinetics of azithromycin, clarithromycin, ciprofloxacin, and cefuroxime in volunteer subjects. | 1996 | Antimicrob. Agents Chemother. | pmid:8807050 |
| Nash KA and Inderlied CB | Rapid detection of mutations associated with macrolide resistance in Mycobacterium avium complex. | 1996 | Antimicrob. Agents Chemother. | pmid:8807078 |
| Hachem CY et al. | Antimicrobial susceptibility testing of Helicobacter pylori. Comparison of E-test, broth microdilution, and disk diffusion for ampicillin, clarithromycin, and metronidazole. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8988762 |
| Flisch CW et al. | [A case of arthritis of the wrist caused by Mycobacterium marinum. Review of the literature]. | 1996 | Ann Chir Main Memb Super | pmid:9026056 |
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| Kondoh K et al. | Inhibitory activity of clarithromycin on biofilm synthesis with Pseudomonas aeruginosa. | 1996 | Acta Otolaryngol Suppl | pmid:8908271 |
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| Santander C et al. | Antimicrobial therapy for Helicobacter pylori infection versus long-term maintenance antisecretion treatment in the prevention of recurrent hemorrhage from peptic ulcer: prospective nonrandomized trial on 125 patients. | 1996 | Am. J. Gastroenterol. | pmid:8759659 |
| Tursi A et al. | Short-term low-dose triple therapy with lansoprazole plus amoxycillin and clarithromycin for Helicobacter pylori eradication. | 1996 | Am. J. Gastroenterol. | pmid:8759696 |
| Debets-Ossenkopp YJ et al. | Mechanism of clarithromycin resistance in clinical isolates of Helicobacter pylori. | 1996 | FEMS Microbiol. Lett. | pmid:8759787 |
| Géhanno P et al. | [Clarithromycin versus amoxicillin-clavulanic acid in the treatment of acute maxillary sinusitis in adults]. | 1996 | Pathol. Biol. | pmid:8763594 |
| Jordan WC | Clarithromycin prophylaxis against Cryptosporidium enteritis in patients with AIDS. | 1996 | J Natl Med Assoc | pmid:8764523 |
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| McLinn S and Williams D | Incidence of antibiotic-resistant Streptococcus pneumoniae and beta-lactamase-positive Haemophilus influenzae in clinical isolates from patients with otitis media. | 1996 | Pediatr. Infect. Dis. J. | pmid:8878239 |
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| Heifets LB | Clarithromycin against Mycobacterium avium complex infections. | 1996 | Tuber. Lung Dis. | pmid:8733409 |
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| Markham A and McTavish D | Clarithromycin and omeprazole as helicobacter pylori eradication therapy in patients with H. pylori-associated gastric disorders. | 1996 | Drugs | pmid:8741237 |
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