| MeSH term | MeSH ID | Detail |
|---|---|---|
| Conjunctival Neoplasms | D003230 | 3 associated lipids |
| Conjunctivitis, Bacterial | D003234 | 3 associated lipids |
| Cross Infection | D003428 | 9 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Cysts | D003560 | 4 associated lipids |
| Dermatitis, Exfoliative | D003873 | 10 associated lipids |
| Drug Eruptions | D003875 | 30 associated lipids |
| Dermatomycoses | D003881 | 17 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- J. Antimicrob. Chemother. (1)
- Clin. Diagn. Lab. Immunol. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Losurdo G et al. | Sequential vs. prolonged 14-day triple therapy for Helicobacter pylori eradication: the meta-analysis may be influenced by 'geographical weighting'. | 2015 | Int. J. Clin. Pract. | pmid:26138290 |
| Tsunemine H et al. | [Successful treatment of relapsed and refractory multiple myeloma by using clarithromycin-lenalidomide, low-dose dexamethasone(BiRd), and melphalan-prednisolone(MP)]. | 2015 | Gan To Kagaku Ryoho | pmid:25981655 |
| Andrianov M et al. | A 15-year-old boy with abdominal pain, growth retardation, and anemia secondary to Helicobacter pylori-associated peptic ulcer. | 2015 | Pediatr Ann | pmid:25806733 |
| Zhao C et al. | [Resistance surveillance of major pathogens for adult community-acquired respiratory tract infections in China: a multicenter study 2012]. | 2015 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:25791651 |
| Trespalacios AA et al. | Improved allele-specific PCR assays for detection of clarithromycin and fluoroquinolone resistant of Helicobacter pylori in gastric biopsies: identification of N87I mutation in GyrA. | 2015 | Diagn. Microbiol. Infect. Dis. | pmid:25600075 |
| Lee H et al. | Comparison of efficacy and safety of levofloxacin-containing versus standard sequential therapy in eradication of Helicobacter pylori infection in Korea. | 2015 | Dig Liver Dis | pmid:25467826 |
| Dierig A et al. | Antibiotic treatment of pertussis: are 7 days really sufficient? | 2015 | Pediatr. Infect. Dis. J. | pmid:25247586 |
| Mailleux M et al. | Unusual pulmonary toxicity of ipilimumab treated by macrolides. | 2015 | Acta Clin Belg | pmid:26790556 |
| Desai S et al. | The Epidemiology of Invasive Haemophilus influenzae Non-Serotype B Disease in Ontario, Canada from 2004 to 2013. | 2015 | PLoS ONE | pmid:26569613 |
| Nishizawa T et al. | Clarithromycin Versus Metronidazole as First-line Helicobacter pylori Eradication: A Multicenter, Prospective, Randomized Controlled Study in Japan. | 2015 | J. Clin. Gastroenterol. | pmid:24921211 |
| Rubio M et al. | Inducible and Acquired Clarithromycin Resistance in the Mycobacterium abscessus Complex. | 2015 | PLoS ONE | pmid:26448181 |
| Renvoisé A et al. | Assessing primary and secondary resistance to clarithromycin and amikacin in infections due to Mycobacterium avium complex. | 2015 | Antimicrob. Agents Chemother. | pmid:26324275 |
| Dingemanse C et al. | Akkermansia muciniphila and Helicobacter typhlonius modulate intestinal tumor development in mice. | 2015 | Carcinogenesis | pmid:26320104 |
| Fan W et al. | An unusual case of folliculitis spinulosa decalvans. | 2016 | Cutis | pmid:27814407 |
| Miftahussurur M et al. | Emerging Helicobacter pylori levofloxacin resistance and novel genetic mutation in Nepal. | 2016 | BMC Microbiol. | pmid:27809767 |
| Sancak S et al. | Intestinal blood flow by Doppler ultrasound: the impact of clarithromycin treatment for feeding intolerance in preterm neonates. | 2016 | J. Matern. Fetal. Neonatal. Med. | pmid:26135789 |
| Uehara H et al. | Comparison of the Anti-angiogenic and Anti-inflammatory Effects of Two Antibiotics: Clarithromycin Versus Moxifloxacin. | 2016 | Curr. Eye Res. | pmid:26125497 |
| Phaw NA and Tsai HH | Eosinophilic gastroenteritis: a challenge to diagnose and treat. | 2016 | BMJ Case Rep | pmid:27613263 |
| Plate A | [Not Available]. | 2016 | Praxis (Bern 1994) | pmid:27606919 |
| Huh CW et al. | Early Attempts to Eradicate Helicobacter pylori after Endoscopic Resection of Gastric Neoplasm Significantly Improve Eradication Success Rates. | 2016 | PLoS ONE | pmid:27588679 |
| Watanabe M et al. | Saturated fatty acids and fatty acid esters promote the polymorphic transition of clarithromycin metastable form I crystal. | 2016 | Int J Pharm | pmid:27553780 |
| Khashei R et al. | High rate of A2142G point mutation associated with clarithromycin resistance among Iranian Helicobacter pylori clinical isolates. | 2016 | APMIS | pmid:27357065 |
| Alarcón-Millán J et al. | Clarithromycin resistance and prevalence of Helicobacter pylori virulent genotypes in patients from Southern México with chronic gastritis. | 2016 | Infect. Genet. Evol. | pmid:27355861 |
| Khonche A et al. | Adjunctive Therapy with Curcumin for Peptic Ulcer: a Randomized Controlled Trial. | 2016 | Drug Res (Stuttg) | pmid:27351245 |
| Büchsel M et al. | A case of septic arthritis caused by a Mycoplasma salivarium strain resistant towards Ciprofloxacin and Clarithromycin in a patient with chronic lymphatic leukemia. | 2016 | Diagn. Microbiol. Infect. Dis. | pmid:27342785 |
| Lin LC et al. | Nonbismuth concomitant quadruple therapy for Helicobacter pylori eradication in Chinese regions: A meta-analysis of randomized controlled trials. | 2016 | World J. Gastroenterol. | pmid:27340362 |
| Mayor S | Short term increase in neuropsychiatric events is seen with H pylori treatment containing clarithromycin. | 2016 | BMJ | pmid:27143325 |
| Shokri-Shirvani J et al. | Letter: global emergence of Helicobacter pylori antibiotic resistance - unanswered questions. | 2016 | Aliment. Pharmacol. Ther. | pmid:27137738 |
| Wong AY et al. | Association Between Acute Neuropsychiatric Events and Helicobacter pylori Therapy Containing Clarithromycin. | 2016 | JAMA Intern Med | pmid:27136661 |
| Zollner-Schwetz I et al. | Primary resistance of Helicobacter pylori is still low in Southern Austria. | 2016 | Int. J. Med. Microbiol. | pmid:27134190 |
| Georgopoulos SD et al. | Randomized clinical trial comparing ten day concomitant and sequential therapies for Helicobacter pylori eradication in a high clarithromycin resistance area. | 2016 | Eur. J. Intern. Med. | pmid:27134145 |
| Todo K et al. | Severe Helicobacter pylori gastritis-related thrombocytopenia and iron deficiency anemia in an adolescent female. | 2016 | Ann. Hematol. | pmid:26957356 |
| Iyer G and Alexander GC | Editorialists' reply to Blake. | 2016 | BMJ | pmid:26957321 |
| Blake Z | Study provides insufficient evidence of a link between clarithromycin and myocardial infarction. | 2016 | BMJ | pmid:26955978 |
| Seyama S et al. | Clarithromycin Resistance Mechanisms of Epidemic β-Lactamase-Nonproducing Ampicillin-Resistant Haemophilus influenzae Strains in Japan. | 2016 | Antimicrob. Agents Chemother. | pmid:26953210 |
| Ji Z et al. | The Association of Age and Antibiotic Resistance of Helicobacter Pylori: A Study in Jiaxing City, Zhejiang Province, China. | 2016 | Medicine (Baltimore) | pmid:26937912 |
| Miglietta F et al. | A rare case of Saprochaete capitata fungemia in a critical ill patient without hematologic and oncological disorders. | 2016 | Rev Esp Quimioter | pmid:26785226 |
| Raymond J et al. | Diagnosis of Helicobacter pylori recurrence: relapse or reinfection? Usefulness of molecular tools. | 2016 | Scand. J. Gastroenterol. | pmid:26784882 |
| Kefeli A et al. | Comparison of three different regimens against Helicobacter pylori as a first-line treatment: A randomized clinical trial. | 2016 | Bosn J Basic Med Sci | pmid:26773183 |
| Iyer G and Alexander GC | Cardiovascular risks associated with clarithromycin. | 2016 | BMJ | pmid:26769796 |
| Wong AY et al. | Cardiovascular outcomes associated with use of clarithromycin: population based study. | 2016 | BMJ | pmid:26768836 |
| Jain SK et al. | Lectin-Conjugated Clarithromycin and Acetohydroxamic Acid-Loaded PLGA Nanoparticles: a Novel Approach for Effective Treatment of H. pylori. | 2016 | AAPS PharmSciTech | pmid:26566630 |
| Di Giulio M et al. | In vitro antimicrobial susceptibility of Helicobacter pylori to nine antibiotics currently used in Central Italy. | 2016 | Scand. J. Gastroenterol. | pmid:26554617 |
| Djennane-Hadibi F et al. | High-Level Primary Clarithromycin Resistance of Helicobacter pylori in Algiers, Algeria: A Prospective Multicenter Molecular Study. | 2016 | Microb. Drug Resist. | pmid:26554340 |
| Gehlot V et al. | Low prevalence of clarithromycin-resistant Helicobacter pylori isolates with A2143G point mutation in the 23S rRNA gene in North India. | 2016 | J Glob Antimicrob Resist | pmid:27530837 |
| Xuan SH et al. | Detection of clarithromycin-resistant Helicobacter pylori in clinical specimens by molecular methods: A review. | 2016 | J Glob Antimicrob Resist | pmid:27436390 |
| Siddiqui TR et al. | Emerging trends of antimicrobial resistance in Helicobacter pylori isolates obtained from Pakistani patients: The need for consideration of amoxicillin and clarithromycin. | 2016 | J Pak Med Assoc | pmid:27339574 |
| Lee J et al. | A new antibiotic regimen treats and prevents intra-amniotic inflammation/infection in patients with preterm PROM. | 2016 | J. Matern. Fetal. Neonatal. Med. | pmid:26441216 |
| Shimizu T and Suzaki H | Past, present and future of macrolide therapy for chronic rhinosinusitis in Japan. | 2016 | Auris Nasus Larynx | pmid:26441370 |
| Apostolopoulos P et al. | Concomitant versus sequential therapy for the treatment of Helicobacter pylori infection: a Greek randomized prospective study. | 2016 | Scand. J. Gastroenterol. | pmid:26435055 |