| MeSH term | MeSH ID | Detail |
|---|---|---|
| Radiation Injuries | D011832 | 14 associated lipids |
| Urticaria | D014581 | 13 associated lipids |
| Rosacea | D012393 | 13 associated lipids |
| Leishmaniasis, Visceral | D007898 | 13 associated lipids |
| Bradycardia | D001919 | 13 associated lipids |
| Abscess | D000038 | 13 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Skin Neoplasms | D012878 | 12 associated lipids |
| Abortion, Spontaneous | D000022 | 12 associated lipids |
| Endophthalmitis | D009877 | 12 associated lipids |
| Liver Failure, Acute | D017114 | 11 associated lipids |
| Shock, Septic | D012772 | 11 associated lipids |
| Influenza, Human | D007251 | 11 associated lipids |
| Uveitis, Anterior | D014606 | 11 associated lipids |
| Urinary Tract Infections | D014552 | 11 associated lipids |
| Exanthema | D005076 | 11 associated lipids |
| Ureteral Obstruction | D014517 | 10 associated lipids |
| Abnormalities, Drug-Induced | D000014 | 10 associated lipids |
| Lung Diseases, Obstructive | D008173 | 10 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Humphreys JE et al. | A clarithromycin sensitivity survey in the United Kingdom using Stokes' method. | 1993 | J. Antimicrob. Chemother. | pmid:8226438 |
| Scaglione F et al. | Immunostimulation by clarithromycin in healthy volunteers and chronic bronchitis patients. | 1993 | J Chemother | pmid:8229150 |
| Andrews J and Wise R | Disk susceptibility testing for clarithromycin. | 1993 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8187799 |
| Dautzenberg B et al. | Clarithromycin and other antimicrobial agents in the treatment of disseminated Mycobacterium avium infections in patients with acquired immunodeficiency syndrome. | 1993 | Arch. Intern. Med. | pmid:8427539 |
| Ji B et al. | Powerful bactericidal activities of clarithromycin and minocycline against Mycobacterium leprae in lepromatous leprosy. | 1993 | J. Infect. Dis. | pmid:8257487 |
| Scaglione F et al. | The postantibiotic effect of clarithromycin and its major human metabolite, 14-hydroxy clarithromycin. | 1993 | J. Antimicrob. Chemother. | pmid:8262876 |
| Guay DR and Craft JC | Overview of the pharmacology of clarithromycin suspension in children and a comparison with that in adults. | 1993 | Pediatr. Infect. Dis. J. | pmid:8295810 |
| Hebert AA et al. | Comparative safety and efficacy of clarithromycin and cefadroxil suspensions in the treatment of mild to moderate skin and skin structure infections in children. | 1993 | Pediatr. Infect. Dis. J. | pmid:8295811 |
| Pukander JS et al. | Clarithromycin vs. amoxicillin suspensions in the treatment of pediatric patients with acute otitis media. | 1993 | Pediatr. Infect. Dis. J. | pmid:8295812 |
| McCarty JM et al. | Comparative safety and efficacy of clarithromycin and amoxicillin/clavulanate in the treatment of acute otitis media in children. | 1993 | Pediatr. Infect. Dis. J. | pmid:8295813 |
| Gooch WM et al. | Clarithromycin and cefaclor suspensions in the treatment of acute otitis media in children. | 1993 | Pediatr. Infect. Dis. J. | pmid:8295814 |
| Klopman G et al. | Anti-Mycobacterium avium activity of quinolones: in vitro activities. | 1993 | Antimicrob. Agents Chemother. | pmid:8239587 |
| Graham DY et al. | Clarithromycin for the eradication of Helicobacter pylori. | 1993 | J. Clin. Gastroenterol. | pmid:8331260 |
| Esvant H et al. | [Primary prophylaxis of cerebral toxoplasmosis in AIDS with clarithromycin]. | 1993 | Presse Med | pmid:8337221 |
| Lederer J et al. | Clarithromycin treatment of posttraumatic Mycobacterium fortuitum wound infection. | 1993 | Pediatr. Infect. Dis. J. | pmid:8414785 |
| de Vega T et al. | Clarithromycin-induced leukocytoclastic vasculitis. | 1993 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8404922 |
| Chu S et al. | Single- and multiple-dose pharmacokinetics of clarithromycin, a new macrolide antimicrobial. | 1993 | J Clin Pharmacol | pmid:8408732 |
| Barradell LB et al. | Clarithromycin. A review of its pharmacological properties and therapeutic use in Mycobacterium avium-intracellulare complex infection in patients with acquired immune deficiency syndrome. | 1993 | Drugs | pmid:7691518 |
| Lazard T et al. | Efficacy of granulocyte colony-stimulating factor and RU-40555 in combination with clarithromycin against Mycobacterium avium complex infection in C57BL/6 mice. | 1993 | Antimicrob. Agents Chemother. | pmid:7684213 |
| Emori M et al. | Therapeutic efficacy of the benzoxazinorifamycin KRM-1648 against experimental Mycobacterium avium infection induced in rabbits. | 1993 | Antimicrob. Agents Chemother. | pmid:7684214 |
| Heifets L et al. | Mycobacterium avium strains resistant to clarithromycin and azithromycin. | 1993 | Antimicrob. Agents Chemother. | pmid:8031351 |
| Ruf B et al. | Effectiveness of the macrolide clarithromycin in the treatment of Mycobacterium avium complex infection in HIV-infected patients. | 1992 Sep-Oct | Infection | pmid:1428183 |
| Friend DR | Polyacrylate resin microcapsules for taste masking of antibiotics. | 1992 Oct-Dec | J Microencapsul | pmid:1403495 |
| de Campora E et al. | Comparative efficacy and safety of roxithromycin and clarithromycin in upper respiratory tract infections. | 1992 May-Jun | Diagn. Microbiol. Infect. Dis. | pmid:1535578 |
| Nilsen OG et al. | Macrolide pharmacokinetics and dose scheduling of roxithromycin. | 1992 May-Jun | Diagn. Microbiol. Infect. Dis. | pmid:1535579 |
| Hoover WW et al. | Clarithromycin in vitro activity enhanced by its major metabolite, 14-hydroxyclarithromycin. | 1992 Mar-Apr | Diagn. Microbiol. Infect. Dis. | pmid:1533827 |
| Chapelsky MC et al. | Renal tubular enzyme effects of clarithromycin in comparison with gentamicin and placebo in volunteers. | 1992 Jul-Aug | Drug Saf | pmid:1355971 |
| Logan RP et al. | Clarithromycin and omeprazole for Helicobacter pylori. | 1992 | Lancet | pmid:1353155 |
| Hammerschlag MR et al. | In vitro activities of azithromycin, clarithromycin, L-ofloxacin, and other antibiotics against Chlamydia pneumoniae. | 1992 | Antimicrob. Agents Chemother. | pmid:1324650 |
| Paulsen P et al. | Influence of azithromycin and other macrolides on the intracellular killing of Staphylococcus aureus by human polymorphonuclear leucocytes of healthy donors and a patient with Chédiak-Higashi syndrome. | 1992 | Chemotherapy | pmid:1324831 |
| Ruf B et al. | Acquired resistance of MAI to clarithromycin. | 1992 | Am. Rev. Respir. Dis. | pmid:1533999 |
| Knothe H | [Short-term therapy of acute respiratory and ORL infections with Clarithromycin]. | 1992 | Z Gesamte Inn Med | pmid:9022402 |
| Berk SL | New macrolide antibiotics. | 1992 | Ann. Intern. Med. | pmid:1386966 |
| Yajko DM et al. | Comparison of the intracellular activities of clarithromycin and erythromycin against Mycobacterium avium complex strains in J774 cells and in alveolar macrophages from human immunodeficiency virus type 1-infected individuals. | 1992 | Antimicrob. Agents Chemother. | pmid:1387302 |
| de Lalla F et al. | Clarithromycin-ciprofloxacin-amikacin for therapy of Mycobacterium avium-Mycobacterium intracellulare bacteremia in patients with AIDS. | 1992 | Antimicrob. Agents Chemother. | pmid:1387303 |
| Cohen Y et al. | Activities of WIN-57273, minocycline, clarithromycin, and 14-hydroxy-clarithromycin against Mycobacterium avium complex in human macrophages. | 1992 | Antimicrob. Agents Chemother. | pmid:1332586 |
| Sifrim D et al. | Comparison of the effects of midecamycin acetate and clarithromycin on gastrointestinal motility in man. | 1992 | Drugs Exp Clin Res | pmid:1292916 |
| Dautzenberg B | [Treatment of atypical mycobacterium infections: current state and therapeutic perspectives]. | 1992 | Rev Pneumol Clin | pmid:1296257 |
| Calzolari E et al. | The efficacy of clarythromycin (A-56268, TE-031) in the treatment of genital chlamydial infection. | 1992 | Drugs Exp Clin Res | pmid:1306155 |
| Klemens SP et al. | Activity of clarithromycin against Mycobacterium avium complex infection in beige mice. | 1992 | Antimicrob. Agents Chemother. | pmid:1336945 |
| Ji B et al. | Bactericidal activities of single or multiple doses of various combinations of new antileprosy drugs and/or rifampin against M. leprae in mice. | 1992 | Int. J. Lepr. Other Mycobact. Dis. | pmid:1338596 |
| Yajko DM | In vitro activity of antimicrobial agents against the Mycobacterium avium complex inside macrophages from HIV1-infected individuals: the link to clinical response to treatment? | 1992 | Res. Microbiol. | pmid:1455069 |
| Sturgill MG and Rapp RP | Clarithromycin: review of a new macrolide antibiotic with improved microbiologic spectrum and favorable pharmacokinetic and adverse effect profiles. | 1992 | Ann Pharmacother | pmid:1421677 |
| Schrock CG | Clarithromycin vs penicillin in the treatment of streptococcal pharyngitis. | 1992 | J Fam Pract | pmid:1453146 |
| Chaisson R | Clarithromycin is effective against M. avium complex in AIDS. | 1992 | Am Fam Physician | pmid:1456199 |
| Ji B et al. | Selection of resistant mutants of Mycobacterium avium in beige mice by clarithromycin monotherapy. | 1992 | Antimicrob. Agents Chemother. | pmid:1482155 |
| Rastogi N and Goh KS | Effect of pH on radiometric MICs of clarithromycin against 18 species of mycobacteria. | 1992 | Antimicrob. Agents Chemother. | pmid:1482156 |
| Rastogi N et al. | Activity of clarithromycin compared with those of other drugs against Mycobacterium paratuberculosis and further enhancement of its extracellular and intracellular activities by ethambutol. | 1992 | Antimicrob. Agents Chemother. | pmid:1482157 |
| Derouin F et al. | Synergistic activity of clarithromycin and minocycline in an animal model of acute experimental toxoplasmosis. | 1992 | Antimicrob. Agents Chemother. | pmid:1482160 |
| Takeda H et al. | [A study to clarify the mechanism of the usefulness of the macrolides--the influence of clarithromycin to biofilm with P. aeruginosa]. | 1992 | Kansenshogaku Zasshi | pmid:1363435 |