| MeSH term | MeSH ID | Detail |
|---|---|---|
| Fibrosis | D005355 | 23 associated lipids |
| Fistula | D005402 | 8 associated lipids |
| Foot Diseases | D005534 | 4 associated lipids |
| Fractures, Open | D005597 | 3 associated lipids |
| Fusobacterium Infections | D005674 | 3 associated lipids |
| Gastritis | D005756 | 27 associated lipids |
| Gastritis, Atrophic | D005757 | 4 associated lipids |
| Gastritis, Hypertrophic | D005758 | 1 associated lipids |
| Gastroesophageal Reflux | D005764 | 10 associated lipids |
| Gastrointestinal Diseases | D005767 | 20 associated lipids |
| Giardiasis | D005873 | 3 associated lipids |
| Glossitis, Benign Migratory | D005929 | 1 associated lipids |
| Granuloma, Plasma Cell | D006104 | 1 associated lipids |
| Hand Dermatoses | D006229 | 5 associated lipids |
| Hearing Disorders | D006311 | 10 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Hemophilia A | D006467 | 10 associated lipids |
| Gastrointestinal Hemorrhage | D006471 | 27 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- FEMS Immunol. Med. Microbiol. (1)
- J. Antimicrob. Chemother. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ji B et al. | How effective is KRM-1648 in treatment of disseminated Mycobacterium avium complex infections in beige mice? | 1996 | Antimicrob. Agents Chemother. | pmid:8834894 |
| Dattwyler RJ et al. | Clarithromycin in treatment of early Lyme disease: a pilot study. | 1996 | Antimicrob. Agents Chemother. | pmid:8834900 |
| Versalovic J et al. | Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori. | 1996 | Antimicrob. Agents Chemother. | pmid:8834903 |
| Yousfi MM et al. | Resolution of a metaplastic duodenal polyp after cure of Helicobacter pylori infection. | 1996 | J. Clin. Gastroenterol. | pmid:8835902 |
| Heifets L | Susceptibility testing of Mycobacterium avium complex isolates. | 1996 | Antimicrob. Agents Chemother. | pmid:8843278 |
| Alper CM et al. | Efficacy of clarithromycin treatment of acute otitis media caused by infection with penicillin-susceptible, -intermediate, and -resistant Streptococcus pneumoniae in the chinchilla. | 1996 | Antimicrob. Agents Chemother. | pmid:8843299 |
| Rana KZ et al. | Clarithromycin does not affect phosphorylation of zidovudine in vitro. | 1996 | Antimicrob. Agents Chemother. | pmid:8843311 |
| Ednie LM et al. | Comparative activities of clarithromycin, erythromycin, and azithromycin against penicillin-susceptible and penicillin-resistant pneumococci. | 1996 | Antimicrob. Agents Chemother. | pmid:8843313 |
| Liviu L et al. | Pancreatitis induced by clarithromycin. | 1996 | Ann. Intern. Med. | pmid:8849171 |
| O'Hara K and Yamamoto K | Reaction of roxithromycin and clarithromycin with macrolide-inactivating enzymes from highly erythromycin-resistant Escherichia coli. | 1996 | Antimicrob. Agents Chemother. | pmid:8849224 |
| Amsden GW | Erythromycin, clarithromycin, and azithromycin: are the differences real? | 1996 Jan-Feb | Clin Ther | pmid:8851453 |
| Vermot D et al. | Efficacy of clarithromycin versus that of clindamycin for single-dose prophylaxis of experimental streptococcal endocarditis. | 1996 | Antimicrob. Agents Chemother. | pmid:8851620 |
| Dammann HG | [Helicobacter pylori eradication: triple therapy versus dual therapy]. | 1996 | Fortschr. Med. | pmid:8852685 |
| Cone LA et al. | Mania due to clarithromycin therapy in a patient who was not infected with human immunodeficiency virus. | 1996 | Clin. Infect. Dis. | pmid:8853002 |
| Yousfi MM et al. | One-week triple therapy with omeprazole, amoxycillin and clarithromycin for treatment of Helicobacter pylori infection. | 1996 | Aliment. Pharmacol. Ther. | pmid:8853767 |
| Schimkat M et al. | Rifabutin-associated anterior uveitis in patients infected with human immunodeficiency virus. | 1996 | Ger J Ophthalmol | pmid:8854102 |
| Chiba N | Omeprazole and clarithromycin with and without metronidazole for the eradication of Helicobacter pylori. | 1996 | Am. J. Gastroenterol. | pmid:8855737 |
| Hackelsberger A and Malfertheiner P | A risk-benefit assessment of drugs used in the eradication of Helicobacter pylori infection. | 1996 | Drug Saf | pmid:8862962 |
| Xu G et al. | Effect of macrolide antibiotics on macrophage functions. | 1996 | Microbiol. Immunol. | pmid:8865152 |
| Ferguson PJ and Saulsbury FT | Successful treatment of chronic Mycobacterium abscessus otitis media with clarithromycin. | 1996 | Pediatr. Infect. Dis. J. | pmid:8866816 |
| Yousfi MM et al. | Metronidazole, ranitidine and clarithromycin combination for treatment of Helicobacter pylori infection (modified Bazzoli's triple therapy). | 1996 | Aliment. Pharmacol. Ther. | pmid:8871452 |
| Fisher M et al. | The management of mycobacterial infections in HIV seropositive individuals. Jefferiss Wing Therapeutics and Protocols Group. | 1996 | Int J STD AIDS | pmid:8876354 |
| Dhaenens L et al. | In-vitro activities of clarithromycin and other antimicrobial agents against Helicobacter pylori isolated from children. | 1996 | J. Antimicrob. Chemother. | pmid:8877551 |
| Tursi A et al. | Helicobacter pylori eradication helps resolve pyloric and duodenal stenosis. | 1996 | J. Clin. Gastroenterol. | pmid:8877648 |
| Thor P et al. | Dysfunction in gastric myoelectric and motor activity in Helicobacter pylori positive gastritis patients with non-ulcer dyspesia. | 1996 | J. Physiol. Pharmacol. | pmid:8877902 |
| McLinn S and Williams D | Incidence of antibiotic-resistant Streptococcus pneumoniae and beta-lactamase-positive Haemophilus influenzae in clinical isolates from patients with otitis media. | 1996 | Pediatr. Infect. Dis. J. | pmid:8878239 |
| Wenisch C et al. | Effect of single oral dose of azithromycin, clarithromycin, and roxithromycin on polymorphonuclear leukocyte function assessed ex vivo by flow cytometry. | 1996 | Antimicrob. Agents Chemother. | pmid:8878577 |
| Pankuch GA et al. | MIC and time-kill study of antipneumococcal activities of RPR 106972 (a new oral streptogramin), RP 59500 (quinupristin-dalfopristin), pyostacine (RP 7293), penicillin G, cefotaxime, erythromycin, and clarithromycin against 10 penicillin-susceptible and -resistant pneumococci. | 1996 | Antimicrob. Agents Chemother. | pmid:8878583 |
| Ji B et al. | Bactericidal activity of single dose of clarithromycin plus minocycline, with or without ofloxacin, against Mycobacterium leprae in patients. | 1996 | Antimicrob. Agents Chemother. | pmid:8878595 |
| Tursi A et al. | One-week low-dose triple therapy vs. two-week medium-dose double therapy for H.pylori infection. | 1996 Jul-Aug | Hepatogastroenterology | pmid:8884304 |
| Giacometti A et al. | In-vitro activity of macrolides alone and in combination with artemisin, atovaquone, dapsone, minocycline or pyrimethamine against Cryptosporidium parvum. | 1996 | J. Antimicrob. Chemother. | pmid:8889715 |
| Tateda K et al. | Direct evidence for antipseudomonal activity of macrolides: exposure-dependent bactericidal activity and inhibition of protein synthesis by erythromycin, clarithromycin, and azithromycin. | 1996 | Antimicrob. Agents Chemother. | pmid:8891128 |
| Patel KB et al. | Comparison of bronchopulmonary pharmacokinetics of clarithromycin and azithromycin. | 1996 | Antimicrob. Agents Chemother. | pmid:8891147 |
| Hunt Gerardo S et al. | Comparison of Etest to broth microdilution method for testing Streptococcus pneumoniae susceptibility to levofloxacin and three macrolides. | 1996 | Antimicrob. Agents Chemother. | pmid:8891154 |
| Wintermeyer SM et al. | Dirithromycin: a new macrolide. | 1996 | Ann Pharmacother | pmid:8893122 |
| Tracy TS and Johns M | Comment: delirium probably induced by clarithromycin in a patient receiving fluoxetine. | 1996 | Ann Pharmacother | pmid:8893135 |
| Ghebremichael S et al. | Antimycobacterial synergism of clarithromycin and rifabutin. | 1996 | Scand. J. Infect. Dis. | pmid:8893404 |
| Spadaccini A et al. | Omeprazole versus ranitidine: short-term triple-therapy in patients with Helicobacter pylori-positive duodenal ulcers. | 1996 | Aliment. Pharmacol. Ther. | pmid:8899094 |
| Three new studies expand understanding of MAC therapy. | 1996 | Am J Health Syst Pharm | pmid:8899122 | |
| Schütze K et al. | Clarithromycin or amoxycillin plus high-dose ranitidine in the treatment of Helicobacter pylori-positive functional dyspepsia. | 1996 | Eur J Gastroenterol Hepatol | pmid:8900907 |
| Flurer CL | Analysis of macrolide antibiotics by capillary electrophoresis. | 1996 | Electrophoresis | pmid:8900943 |
| Segreti J et al. | In vitro activity of macrolides against intracellular Legionella pneumophila. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8902407 |
| Pavlopoulou J et al. | Randomized controlled study of clarithromycin versus cefaclor suspensions in the treatment of acute otitis media in children. | 1995 | J Chemother | pmid:8904139 |
| Kondoh K et al. | Inhibitory activity of clarithromycin on biofilm synthesis with Pseudomonas aeruginosa. | 1996 | Acta Otolaryngol Suppl | pmid:8908271 |
| Koeck JL et al. | Disseminated Mycobacterium simiae infection in a patient with AIDS: clinical features and treatment. | 1996 | Clin. Infect. Dis. | pmid:8909856 |
| Kuo CC et al. | In vitro activities of azithromycin, clarithromycin, and other antibiotics against Chlamydia pneumoniae. | 1996 | Antimicrob. Agents Chemother. | pmid:8913488 |
| Aoyama T et al. | Efficacy of short-term treatment of pertussis with clarithromycin and azithromycin. | 1996 | J. Pediatr. | pmid:8917247 |
| Muñoz N et al. | Chemoprevention trial on precancerous lesions of the stomach in Venezuela: summary of study design and baseline data. | 1996 | IARC Sci. Publ. | pmid:8923024 |
| van der Hulst RW et al. | Therapeutic options after failed Helicobacter pylori eradication therapy. | 1996 | Am. J. Gastroenterol. | pmid:8931413 |
| Alder JD et al. | Relevance of the ferret model of Helicobacter-induced gastritis to evaluation of antibacterial therapies. | 1996 | Am. J. Gastroenterol. | pmid:8931416 |