| MeSH term | MeSH ID | Detail |
|---|---|---|
| Whooping Cough | D014917 | 6 associated lipids |
| Uveitis, Anterior | D014606 | 11 associated lipids |
| Urticaria | D014581 | 13 associated lipids |
| Urination Disorders | D014555 | 9 associated lipids |
| Urinary Tract Infections | D014552 | 11 associated lipids |
| Urethritis | D014526 | 9 associated lipids |
| Ureteral Obstruction | D014517 | 10 associated lipids |
| Ureteral Diseases | D014515 | 3 associated lipids |
| Typhoid Fever | D014435 | 2 associated lipids |
| Tuberculosis, Spinal | D014399 | 1 associated lipids |
| Tuberculosis, Pulmonary | D014397 | 18 associated lipids |
| Tuberculosis, Ocular | D014392 | 1 associated lipids |
| Tuberculosis, Avian | D014379 | 2 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Tenosynovitis | D013717 | 3 associated lipids |
| Syphilis | D013587 | 6 associated lipids |
| Synovitis | D013585 | 15 associated lipids |
| Surgical Wound Infection | D013530 | 7 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- J. Antimicrob. Chemother. (1)
- Clin. Diagn. Lab. Immunol. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Braden B | The best and worst treatments for Helicobacter pylori. | 2015 | BMJ | pmid:26290321 |
| Li BZ et al. | Comparative effectiveness and tolerance of treatments for Helicobacter pylori: systematic review and network meta-analysis. | 2015 | BMJ | pmid:26290044 |
| Haider RB et al. | A randomized-controlled study to compare the efficacy of sequential therapy with standard triple therapy for Helicobacter pylori eradication in an Irish population. | 2015 | Eur J Gastroenterol Hepatol | pmid:26287955 |
| Shallom SJ et al. | New Real-Time PCR Assays for Detection of Inducible and Acquired Clarithromycin Resistance in the Mycobacterium abscessus Group. | 2015 | J. Clin. Microbiol. | pmid:26269619 |
| Zagari RM et al. | Guidelines for the management of Helicobacter pylori infection in Italy: The III Working Group Consensus Report 2015. | 2015 | Dig Liver Dis | pmid:26253555 |
| Sprague J et al. | Cutaneous infection with Mycobacterium kansasii in a patient with myelodysplastic syndrome and Sweet syndrome. | 2015 | Cutis | pmid:26244358 |
| Sharara AI et al. | Letter: clarithromycin dose for H. pylori therapy remains unresolved--authors' reply. | 2015 | Aliment. Pharmacol. Ther. | pmid:26238584 |
| Graham DY and Gisbert JP | Letter: clarithromycin dose for H. pylori therapy remains unresolved. | 2015 | Aliment. Pharmacol. Ther. | pmid:26238583 |
| Navarro-Jarabo JM et al. | Prevalence of Primary Resistance of Helicobacter pylori to Clarithromycin and Levofloxacin in Southern Spain. | 2015 | Digestion | pmid:26227669 |
| Ufuk A et al. | In Vitro Assessment of Uptake and Lysosomal Sequestration of Respiratory Drugs in Alveolar Macrophage Cell Line NR8383. | 2015 | Pharm. Res. | pmid:26224396 |
| Zhang T | Physiologically based pharmacokinetic modeling of disposition and drug-drug interactions for atorvastatin and its metabolites. | 2015 | Eur J Pharm Sci | pmid:26116278 |
| Fraser LA et al. | Calcium channel blocker-clarithromycin drug interaction did not increase the risk of nonvertebral fracture: a population-based study. | 2015 | Ann Pharmacother | pmid:25429094 |
| Lee SJ et al. | Clarithromycin Attenuates Radiation-Induced Lung Injury in Mice. | 2015 | PLoS ONE | pmid:26114656 |
| Dimer F et al. | Inhalable Clarithromycin Microparticles for Treatment of Respiratory Infections. | 2015 | Pharm. Res. | pmid:26113237 |
| Kasai A et al. | Prevalence and molecular analysis of macrolide-resistant Moraxella catarrhalis clinical isolates in Japan, following emergence of the highly macrolide-resistant strain NSH1 in 2011. | 2015 | J. Med. Microbiol. | pmid:25934551 |
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| Jeong BH et al. | Intermittent antibiotic therapy for nodular bronchiectatic Mycobacterium avium complex lung disease. | 2015 | Am. J. Respir. Crit. Care Med. | pmid:25393520 |
| Hill FJ et al. | From a fish tank injury to hospital haemodialysis: the serious consequences of drug interactions. | 2015 | BMJ Case Rep | pmid:26106178 |
| Yu T et al. | Study on clarithromycin lactobionate based dual selector systems for the enantioseparation of basic drugs in capillary electrophoresis. | 2015 | J Sep Sci | pmid:26097042 |
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| Takahashi C et al. | Observation of antibacterial effect of biodegradable polymeric nanoparticles on Staphylococcus epidermidis biofilm using FE-SEM with an ionic liquid. | 2015 | Microscopy (Oxf) | pmid:25757698 |
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| Essilfie AT et al. | Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma. | 2015 | Thorax | pmid:25746630 |
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| Brown-Elliott BA et al. | Absence of a functional erm gene in isolates of Mycobacterium immunogenum and the Mycobacterium mucogenicum group, based on in vitro clarithromycin susceptibility. | 2015 | J. Clin. Microbiol. | pmid:25568437 |
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| Park JB et al. | Modulation of microenvironmental pH and utilization of alkalizers in crystalline solid dispersion for enhanced solubility and stability of clarithromicin. | 2015 | Arch. Pharm. Res. | pmid:25213008 |
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| Pea F et al. | Everolimus overexposure in a heart transplant patient receiving clarithromycin for the treatment of pneumonia. | 2015 | Transpl Infect Dis | pmid:26296391 |
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| Fan Y et al. | High and low doses of clarithromycin treatment are associated with different clinical efficacies and immunomodulatory properties in chronic rhinosinusitis. | 2014 | J Laryngol Otol | pmid:24555753 |
| Hanson KE et al. | Rapid molecular detection of inducible macrolide resistance in Mycobacterium chelonae and M. abscessus strains: a replacement for 14-day susceptibility testing? | 2014 | J. Clin. Microbiol. | pmid:24554745 |
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| Pathak V et al. | Macrolide use leads to clinical and radiological improvement in patients with cryptogenic organizing pneumonia. | 2014 | Ann Am Thorac Soc | pmid:24460438 |
| Jesus FP et al. | In vitro synergism observed with azithromycin, clarithromycin, minocycline, or tigecycline in association with antifungal agents against Pythium insidiosum. | 2014 | Antimicrob. Agents Chemother. | pmid:25001300 |
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| Higashi F et al. | Additional treatment with clarithromycin reduces fever duration in patients with influenza. | 2014 | Respir Investig | pmid:25169846 |
| Lyons J et al. | An unusual lung mass post stem cell transplantation. | 2014 | Transpl Infect Dis | pmid:24995624 |
| Togami K et al. | Involvement of intestinal permeability in the oral absorption of clarithromycin and telithromycin. | 2014 | Biopharm Drug Dispos | pmid:24801141 |
| Bernut A et al. | In vivo assessment of drug efficacy against Mycobacterium abscessus using the embryonic zebrafish test system. | 2014 | Antimicrob. Agents Chemother. | pmid:24798271 |
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